메뉴 건너뛰기




Volumn 319, Issue 3, 2004, Pages 847-853

An anti-inflammatory role for N-acetyl aspartate in stimulated human astroglial cells

Author keywords

Astrocyte astroglia ; Cyclooxygenase; Inhibition; Intracellular calcium; N Acetyl aspartate; NF B; Prostaglandin

Indexed keywords

CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; IONOMYCIN; N ACETYLASPARTIC ACID;

EID: 2942567955     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.200     Document Type: Article
Times cited : (33)

References (46)
  • 1
    • 0030901106 scopus 로고    scopus 로고
    • A review of phylogenetic and metabolic relationships between the acylamino acids, N-acetyl-L-aspartic acid and N-acetyl-L-histidine, in the vertebrate nervous system
    • Baslow M.H. A review of phylogenetic and metabolic relationships between the acylamino acids, N-acetyl-L-aspartic acid and N-acetyl-L-histidine, in the vertebrate nervous system. J. Neurochem. 68:1997;1335-1344
    • (1997) J. Neurochem. , vol.68 , pp. 1335-1344
    • Baslow, M.H.1
  • 2
    • 0031731910 scopus 로고    scopus 로고
    • N-Acetyl aspartate: A marker for neuronal loss or mitochondrial dysfunction
    • Clark J.B. N-Acetyl aspartate: a marker for neuronal loss or mitochondrial dysfunction. Dev. Neurosci. 20:1998;271-276
    • (1998) Dev. Neurosci. , vol.20 , pp. 271-276
    • Clark, J.B.1
  • 3
    • 0028978925 scopus 로고
    • N-Acetylaspartate in neuropsychiatric disorders
    • Tsai G., Coyle J.T. N-Acetylaspartate in neuropsychiatric disorders. Prog. Neurobiol. 46:1995;531-540
    • (1995) Prog. Neurobiol. , vol.46 , pp. 531-540
    • Tsai, G.1    Coyle, J.T.2
  • 4
    • 0034799866 scopus 로고    scopus 로고
    • Quantitative proton MR spectroscopic imaging of normal human cerebellum and brain stem
    • Jacobs M.A., Horska A., van Zijl P.C., Barker P.B. Quantitative proton MR spectroscopic imaging of normal human cerebellum and brain stem. Magn. Reson. Med. 46:2001;699-705
    • (2001) Magn. Reson. Med. , vol.46 , pp. 699-705
    • Jacobs, M.A.1    Horska, A.2    Van Zijl, P.C.3    Barker, P.B.4
  • 5
    • 0031964205 scopus 로고    scopus 로고
    • 1H magnetic resonance spectroscopy
    • 1H magnetic resonance spectroscopy. Magn. Reson. Med. 39:1998;28-33
    • (1998) Magn. Reson. Med. , vol.39 , pp. 28-33
    • Wang, Y.1    Li, S.J.2
  • 6
    • 0030846501 scopus 로고    scopus 로고
    • Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS
    • Pouwels P.J., Frahm J. Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS. NMR Biomed. 10:1997;73-78
    • (1997) NMR Biomed. , vol.10 , pp. 73-78
    • Pouwels, P.J.1    Frahm, J.2
  • 7
  • 8
    • 0032470844 scopus 로고    scopus 로고
    • Proton MR spectroscopic findings correspond to neuropsychological function in traumatic brain injury
    • Friedman S.D., Brooks W.M., Jung R.E., Hart B.L., Yeo R.A. Proton MR spectroscopic findings correspond to neuropsychological function in traumatic brain injury. AJNR Am. J. Neuroradiol. 19:1998;1879-1885
    • (1998) AJNR Am. J. Neuroradiol. , vol.19 , pp. 1879-1885
    • Friedman, S.D.1    Brooks, W.M.2    Jung, R.E.3    Hart, B.L.4    Yeo, R.A.5
  • 9
    • 0037409849 scopus 로고    scopus 로고
    • N-Acetylaspartate in the vertebrate brain: Metabolism and function
    • Baslow M.H. N-Acetylaspartate in the vertebrate brain: metabolism and function. Neurochem. Res. 28:2003;941-953
    • (2003) Neurochem. Res. , vol.28 , pp. 941-953
    • Baslow, M.H.1
  • 10
    • 0034006477 scopus 로고    scopus 로고
    • Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose transgenic Huntington's disease mice
    • Jenkins B.G., Klivenyi P., Kustermann E., Andreassen O.A., Ferrante R.J., Rosen B.R., Beal M.F. Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose transgenic Huntington's disease mice. J. Neurochem. 74:2000;2108-2119
    • (2000) J. Neurochem. , vol.74 , pp. 2108-2119
    • Jenkins, B.G.1    Klivenyi, P.2    Kustermann, E.3    Andreassen, O.A.4    Ferrante, R.J.5    Rosen, B.R.6    Beal, M.F.7
  • 13
    • 0038458827 scopus 로고    scopus 로고
    • N-Acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: Influence of neuronal elements, reactive gliosis, and tissue atrophy
    • Konaka K., Ueda H., Li J.Y., Matsumoto M., Sakoda S., Yanagihara T. N-Acetylaspartate to total creatine ratio in the hippocampal CA1 sector after transient cerebral ischemia in gerbils: influence of neuronal elements, reactive gliosis, and tissue atrophy. J. Cereb. Blood Flow Metab. 23:2003;700-708
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 700-708
    • Konaka, K.1    Ueda, H.2    Li, J.Y.3    Matsumoto, M.4    Sakoda, S.5    Yanagihara, T.6
  • 17
    • 0031031171 scopus 로고    scopus 로고
    • Transient elevation of interstitial N-acetylaspartate in reversible global brain ischemia
    • Sager T.N., Fink-Jensen A., Hansen A.J. Transient elevation of interstitial N-acetylaspartate in reversible global brain ischemia. J. Neurochem. 68:1997;675-682
    • (1997) J. Neurochem. , vol.68 , pp. 675-682
    • Sager, T.N.1    Fink-Jensen, A.2    Hansen, A.J.3
  • 18
  • 19
    • 0033798624 scopus 로고    scopus 로고
    • Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain
    • Huang W., Wang H., Kekuda R., Fei Y.J., Friedrich A., Wang J., Conway S.J., Cameron R.S., Leibach F.H., Ganapathy V. Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain. J. Pharmacol. Exp. Ther. 295:2000;392-403
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 392-403
    • Huang, W.1    Wang, H.2    Kekuda, R.3    Fei, Y.J.4    Friedrich, A.5    Wang, J.6    Conway, S.J.7    Cameron, R.S.8    Leibach, F.H.9    Ganapathy, V.10
  • 20
    • 0034890751 scopus 로고    scopus 로고
    • Intraneuronal N-acetylaspartate supplies acetyl groups for myelin lipid synthesis: Evidence for myelin-associated aspartoacylase
    • Chakraborty G., Mekala P., Yahya D., Wu G., Ledeen R.W. Intraneuronal N-acetylaspartate supplies acetyl groups for myelin lipid synthesis: evidence for myelin-associated aspartoacylase. J. Neurochem. 78:2001;736-745
    • (2001) J. Neurochem. , vol.78 , pp. 736-745
    • Chakraborty, G.1    Mekala, P.2    Yahya, D.3    Wu, G.4    Ledeen, R.W.5
  • 21
    • 0036162622 scopus 로고    scopus 로고
    • Evidence supporting a role for N-acetyl-L-aspartate as a molecular water pump in myelinated neurons in the central nervous system. An analytical review
    • Baslow M.H. Evidence supporting a role for N-acetyl-L-aspartate as a molecular water pump in myelinated neurons in the central nervous system. An analytical review. Neurochem. Int. 40:2002;295-300
    • (2002) Neurochem. Int. , vol.40 , pp. 295-300
    • Baslow, M.H.1
  • 22
    • 0035807799 scopus 로고    scopus 로고
    • A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin
    • Ouellet M., Riendeau D., Percival M.D. A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin. Proc. Natl. Acad. Sci. USA. 98:2001;14583-14588
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14583-14588
    • Ouellet, M.1    Riendeau, D.2    Percival, M.D.3
  • 23
    • 0030821471 scopus 로고    scopus 로고
    • Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes
    • Wang Z., Tymianski M., Jones O.T., Nedergaard M. Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes. J. Neurosci. 17:1997;7359-7371
    • (1997) J. Neurosci. , vol.17 , pp. 7359-7371
    • Wang, Z.1    Tymianski, M.2    Jones, O.T.3    Nedergaard, M.4
  • 24
    • 0034816925 scopus 로고    scopus 로고
    • Cyclooxygenase-independent actions of cyclooxygenase inhibitors
    • Tegeder I., Pfeilschifter J., Geisslinger G. Cyclooxygenase-independent actions of cyclooxygenase inhibitors. FASEB J. 15:2001;2057-2072
    • (2001) FASEB J. , vol.15 , pp. 2057-2072
    • Tegeder, I.1    Pfeilschifter, J.2    Geisslinger, G.3
  • 25
    • 0028339780 scopus 로고
    • Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
    • Lecomte M., Laneuville O., Ji C., DeWitt D.L., Smith W.L. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. J. Biol. Chem. 269:1994;13207-13215
    • (1994) J. Biol. Chem. , vol.269 , pp. 13207-13215
    • Lecomte, M.1    Laneuville, O.2    Ji, C.3    Dewitt, D.L.4    Smith, W.L.5
  • 26
    • 0038309422 scopus 로고    scopus 로고
    • Enhancement of colon carcinogenesis by prostaglandin E2 administration
    • Kawamori T., Uchiya N., Sugimura T., Wakabayashi K. Enhancement of colon carcinogenesis by prostaglandin E2 administration. Carcinogenesis. 24:2003;985-990
    • (2003) Carcinogenesis , vol.24 , pp. 985-990
    • Kawamori, T.1    Uchiya, N.2    Sugimura, T.3    Wakabayashi, K.4
  • 27
    • 1842841557 scopus 로고    scopus 로고
    • Role of COX-2, VEGF and cyclin D1 in mammary infiltrating duct carcinoma
    • Lim S.C. Role of COX-2, VEGF and cyclin D1 in mammary infiltrating duct carcinoma. Oncol. Rep. 10:2003;1241-1249
    • (2003) Oncol. Rep. , vol.10 , pp. 1241-1249
    • Lim, S.C.1
  • 29
    • 0037512474 scopus 로고    scopus 로고
    • Low-dose prostacyclin improves cortical perfusion following experimental brain injury in the rat
    • Bentzer P., Venturoli D., Carlsson O., Grande P.O. Low-dose prostacyclin improves cortical perfusion following experimental brain injury in the rat. J. Neurotrauma. 20:2003;447-461
    • (2003) J. Neurotrauma , vol.20 , pp. 447-461
    • Bentzer, P.1    Venturoli, D.2    Carlsson, O.3    Grande, P.O.4
  • 30
    • 16944362194 scopus 로고    scopus 로고
    • Estradiol enhances prostaglandin E2 receptor gene expression in luteinizing hormone-releasing hormone (LHRH) neurons and facilitates the LHRH response to PGE2 by activating a glia-to-neuron signaling pathway
    • Rage F., Lee B.J., Ma Y.J., Ojeda S.R. Estradiol enhances prostaglandin E2 receptor gene expression in luteinizing hormone-releasing hormone (LHRH) neurons and facilitates the LHRH response to PGE2 by activating a glia-to-neuron signaling pathway. J. Neurosci. 17:1997;9145-9156
    • (1997) J. Neurosci. , vol.17 , pp. 9145-9156
    • Rage, F.1    Lee, B.J.2    Ma, Y.J.3    Ojeda, S.R.4
  • 31
    • 0034145774 scopus 로고    scopus 로고
    • Spongy degeneration of the brain, Canavan disease: Biochemical and molecular findings
    • Matalon R.M., Michals-Matalon K. Spongy degeneration of the brain, Canavan disease: biochemical and molecular findings. Front. Biosci. 5:2000;D307-D311
    • (2000) Front. Biosci. , vol.5 , pp. 307-D311
    • Matalon, R.M.1    Michals-Matalon, K.2
  • 32
    • 0031243417 scopus 로고    scopus 로고
    • Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms
    • Baslow M.H., Resnik T.R. Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms. J. Mol. Neurosci. 9:1997;109-125
    • (1997) J. Mol. Neurosci. , vol.9 , pp. 109-125
    • Baslow, M.H.1    Resnik, T.R.2
  • 33
    • 0033612963 scopus 로고    scopus 로고
    • IL-1beta differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels
    • John G.R., Scemes E., Suadicani S.O., Liu J.S., Charles P.C., Lee S.C., Spray D.C., Brosnan C.F. IL-1beta differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels. Proc. Natl. Acad. Sci. USA. 96:1999;11613-11618
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11613-11618
    • John, G.R.1    Scemes, E.2    Suadicani, S.O.3    Liu, J.S.4    Charles, P.C.5    Lee, S.C.6    Spray, D.C.7    Brosnan, C.F.8
  • 34
    • 0034682506 scopus 로고    scopus 로고
    • Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons
    • Parpura V., Haydon P.G. Physiological astrocytic calcium levels stimulate glutamate release to modulate adjacent neurons. Proc. Natl. Acad. Sci. USA. 97:2000;8629-8634
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8629-8634
    • Parpura, V.1    Haydon, P.G.2
  • 35
    • 0030452386 scopus 로고    scopus 로고
    • Intracellular chelation of calcium prevents cell damage following severe hypoxia in the rat cerebral cortex as studied by NMR spectroscopy ex vivo
    • Grohn O., Kauppinen R. Intracellular chelation of calcium prevents cell damage following severe hypoxia in the rat cerebral cortex as studied by NMR spectroscopy ex vivo. Cell Calcium. 20:1996;509-514
    • (1996) Cell Calcium , vol.20 , pp. 509-514
    • Grohn, O.1    Kauppinen, R.2
  • 36
    • 0029121127 scopus 로고
    • N-Acetylaspartate complexes with calcium and lanthanide ions
    • Rubin Y., Connelly G.P., Lenkinski R.E. N-Acetylaspartate complexes with calcium and lanthanide ions. J. Inorg. Biochem. 60:1995;31-43
    • (1995) J. Inorg. Biochem. , vol.60 , pp. 31-43
    • Rubin, Y.1    Connelly, G.P.2    Lenkinski, R.E.3
  • 37
    • 0031030073 scopus 로고    scopus 로고
    • Mechanism involved in initiation and propagation of receptor-induced intercellular calcium signaling in cultured rat astrocytes
    • Venance L., Stella N., Glowinski J., Giaume C. Mechanism involved in initiation and propagation of receptor-induced intercellular calcium signaling in cultured rat astrocytes. J. Neurosci. 17:1997;1981-1992
    • (1997) J. Neurosci. , vol.17 , pp. 1981-1992
    • Venance, L.1    Stella, N.2    Glowinski, J.3    Giaume, C.4
  • 39
    • 0032742779 scopus 로고    scopus 로고
    • Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells
    • Sanzgiri R.P., Araque A., Haydon P.G. Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. J. Neurobiol. 41:1999;221-229
    • (1999) J. Neurobiol. , vol.41 , pp. 221-229
    • Sanzgiri, R.P.1    Araque, A.2    Haydon, P.G.3
  • 40
    • 0031982964 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation
    • Schwenger P., Alpert D., Skolnik E.Y., Vilcek J. Activation of p38 mitogen-activated protein kinase by sodium salicylate leads to inhibition of tumor necrosis factor-induced IkappaB alpha phosphorylation and degradation. Mol. Cell. Biol. 18:1998;78-84
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 78-84
    • Schwenger, P.1    Alpert, D.2    Skolnik, E.Y.3    Vilcek, J.4
  • 41
    • 0034192392 scopus 로고    scopus 로고
    • Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression
    • Murono S., Yoshizaki T., Sato H., Takeshita H., Furukawa M., Pagano J.S. Aspirin inhibits tumor cell invasiveness induced by Epstein-Barr virus latent membrane protein 1 through suppression of matrix metalloproteinase-9 expression. Cancer Res. 60:2000;2555-2561
    • (2000) Cancer Res. , vol.60 , pp. 2555-2561
    • Murono, S.1    Yoshizaki, T.2    Sato, H.3    Takeshita, H.4    Furukawa, M.5    Pagano, J.S.6
  • 43
    • 0029162193 scopus 로고
    • Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid
    • Camacho M., Godessart N., Anton R., Garcia M., Vila L. Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. J. Biol. Chem. 270:1995;17279-17286
    • (1995) J. Biol. Chem. , vol.270 , pp. 17279-17286
    • Camacho, M.1    Godessart, N.2    Anton, R.3    Garcia, M.4    Vila, L.5
  • 44
    • 0029906617 scopus 로고    scopus 로고
    • Regulation of nerve growth factor mRNA by interleukin-1 in rat hippocampal astrocytes is mediated by NFkappaB
    • Friedman W.J., Thakur S., Seidman L., Rabson A.B. Regulation of nerve growth factor mRNA by interleukin-1 in rat hippocampal astrocytes is mediated by NFkappaB. J. Biol. Chem. 271:1996;31115-31120
    • (1996) J. Biol. Chem. , vol.271 , pp. 31115-31120
    • Friedman, W.J.1    Thakur, S.2    Seidman, L.3    Rabson, A.B.4
  • 45
    • 0035153052 scopus 로고    scopus 로고
    • Expression of nuclear factor kappaB and tumor necrosis factor alpha in the mouse brain after experimental thermal ablation injury
    • Nomoto Y., Yamamoto M., Fukushima T., Kimura H., Ohshima K., Tomonaga M. Expression of nuclear factor kappaB and tumor necrosis factor alpha in the mouse brain after experimental thermal ablation injury. Neurosurgery. 48:2001;158-166
    • (2001) Neurosurgery , vol.48 , pp. 158-166
    • Nomoto, Y.1    Yamamoto, M.2    Fukushima, T.3    Kimura, H.4    Ohshima, K.5    Tomonaga, M.6
  • 46
    • 0036273683 scopus 로고    scopus 로고
    • IL-1 beta signaling in glial cells in wildtype and IL-1RI deficient mice
    • Parker L.C., Luheshi G.N., Rothwell N.J., Pinteaux E. IL-1 beta signaling in glial cells in wildtype and IL-1RI deficient mice. Br. J. Pharmacol. 136:2002;312-320
    • (2002) Br. J. Pharmacol. , vol.136 , pp. 312-320
    • Parker, L.C.1    Luheshi, G.N.2    Rothwell, N.J.3    Pinteaux, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.