Telomere erosion triggers growth arrest but not cell death in human cancer cells retaining wild-type p53: Implications for antitelomerase therapy

Oncogene

Volumn 23, Issue 23, 2004, Pages 4136-4145

  Preto, Ana ^a   Singhrao, Sim K ^b   Haughton, Michele F ^b   Kipling, David ^b   Wynford Thomas, David ^b   Jones, Christopher J ^b  

^a UNIVERSITY OF PORTO   (Portugal)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Cancer; p53; Senescence; Telomerase; Therapy

Indexed keywords

BETA GALACTOSIDASE; BROXURIDINE; ENZYME INHIBITOR; NEUTRALIZING ANTIBODY; PROTEIN P21; PROTEIN P53; TELOMERASE INHIBITOR; TELOMERASE REVERSE TRANSCRIPTASE; DNA BINDING PROTEIN; TELOMERASE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL GROWTH; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; SENESCENCE; TELOMERE; THYROID CANCER; GENETICS; METABOLISM; PHYSIOLOGY; THYROID TUMOR;

APOPTOSIS; DNA-BINDING PROTEINS; HUMANS; TELOMERASE; TELOMERE; THYROID NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 2942537690     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207564     Document Type: Article

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