Development of real-time NASBA assays with molecular beacon detection to quantify mRNA coding for HHV-8 lytic and latent genes

BMC Infectious Diseases

Volumn 2, Issue , 2002, Pages

  Polstra, Abeltje M ^a   Goudsmit, J ^a   Cornelissen, M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITOR; GROWTH FACTOR; LATENCY ASSOCIATED NUCLEAR ANTIGEN; MEMBRANE RECEPTOR; MESSENGER RNA; VIRUS RNA; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BCL 2 PROTEIN, HUMAN HERPESVIRUS 8; BCL-2 PROTEIN, HUMAN HERPESVIRUS 8; CARRIER PROTEIN; INTERLEUKIN 6; K8 PROTEIN, HUMAN HERPESVIRUS 8; LATENCY-ASSOCIATED NUCLEAR ANTIGEN; NUCLEAR PROTEIN; ONCOPROTEIN; REPRESSOR PROTEIN; VIRUS ANTIGEN; VIRUS PROTEIN;

ADULT; CASE REPORT; CONTROLLED STUDY; GENE AMPLIFICATION; GENE EXPRESSION; GENE SEQUENCE; GENETIC CODE; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 8; IN VITRO STUDY; KAPOSI SARCOMA; MALE; NUCLEIC ACID SEQUENCE BASED AMPLIFICATION; OPEN READING FRAME; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; ARTICLE; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MONONUCLEAR CELL; PHYSIOLOGY; VIROLOGY; VIRUS GENE; VIRUS LATENCY;

ANTIGENS, VIRAL; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CARRIER PROTEINS; GENES, VIRAL; HERPESVIRUS 8, HUMAN; HUMANS; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; NUCLEAR PROTEINS; ONCOGENE PROTEINS; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, VIRAL; SARCOMA, KAPOSI; SELF-SUSTAINED SEQUENCE REPLICATION; SENSITIVITY AND SPECIFICITY; VIRAL PROTEINS; VIRAL STRUCTURAL PROTEINS; VIRUS LATENCY;

EID: 2942534199     PISSN: 14712334     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2334-2-18     Document Type: Review

References (62)

1. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS: Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994, 266:1865-1869
2. Cesarman E, Chang Y, Moore PS, Said JW, Knowles DM: Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. New England Journal of Medicine 1995, 332:1186-1191
3. Cesarman E, Moore PS, Rao PH, Inghirami G, Knowles DM, Chang Y: In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences. Blood 1995, 86:2708-2714
4. Soulier J, Grollet L, Oksenhendler E, Cacoub P, Cazals-Hatem D, Babinet P, D'Agay M-F, Clauvel J-P, Raphael M, Degos L, et al: Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood 1995, 86:1276-1280
5. Rettig MB, Ma HJ, Vescio RA, Pold M, Schiller G, Belson D, Savage A, Nishikubo C, Wu C, et al: Kaposi's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients. Science 1997, 276:1851-1854
6. LaDuca JR, Love JL, Abbott LZ, Dube S, Freidman-Kien AE, Poiesz BJ: Detection of human herpesvirus 8 DNA sequences in tissues and bodily fluids. Journal of Infectious Diseases 1998, 178:1610-1615
7. Stamey FR, Patel MM, Holloway BP, Pellett PE: Quantitative, fluorogenic probe pcr assay for detection of human herpesvirus 8 dna in clinical specimens. J Clin Microbiol 2001, 39:3537-3540
8. Renwick N, Halaby T, Weverling GJ, Dukers NHTM, Simpson GR, Coutinho RA, Lange LMA, Schulz TF, Goudsmit J: Seroconversion for human herpesvirus 8 during HIV infection is highly predictive of Kaposi's sarcoma. AIDS 1998, 12:2481-2488
9. Jenner RG, Alba MM, Boshoff C, Kellam P: Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays. Journal of Virology 2001, 75:891-902
10. Gao SJ, Kingsley L, Li M, Zheng W, Parravicini C, Ziegler J, Newton R, Rinaldo CR, Saah A, Phair J, et al: KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med 1996, 2:925-928
11. Kedes DH, Operskalski E, Busch M, Kohn R, Flood J, Ganem D: The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission. Nat Med 1996, 2:918-924
12. Lennette ET, Blackbourn DJ, Levy JA: Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 1996, 348:858-861
13. Koelle DM, Huang ML, Chandran B, Vieira J, Piepkorn M, Corey L: Frequent detection of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) DNA in saliva of human immunodeficiency virus-infected men: clinical and immunologic correlates. J Infect Dis 1997, 176:94-102
14. Chatlynne LG, Lapps W, Handy M, Huang YQ, Masood R, Hamilton AS, Said JW, Koeffler HP, Kaplan MH, Friedman-Kien A, et al: Detection and titration of human herpesvirus-8-specific antibodies in sera from blood donors, acquired immunodeficiency syndrome patients, and Kaposi's sarcoma patients using a whole virus enzyme-linked immunosorbent assay. Blood 1998, 92:53-58
15. Davis DA, Humphrey RW, Newcomb FM, O'Brien TR, Goedert JJ, Straus SE, Yarchoan R: Detection of serum antibodies to a Kaposi's sarcoma-associated herpesvirus-specific peptide. J Infect Dis 1997, 175:1071-1079
16. Smith MS, Bloomer C, Horvat R, Goldstein E, Casparian JM, Chandran B: Detection of human herpesvirus 8 DNA in Kaposi's sarcoma lesions and peripheral blood of human immunodeficiency virus-positive patients and correlation with serologic measurements. J Infect Dis 1997, 176:84-93
17. Spira TJ, Lam L, Dollard SC, Meng YX, Pau CP, Black JB, Burns D, Cooper B, Hamid M, Huong J, et al: Comparison of serologic assays and PCR for diagnosis of human herpesvirus 8 infection. J Clin Microbiol 2000, 38:2174-2180
18. Staskus KA, Zhong W, Gebhard K, Herndier B, Wang H, Renne R, Beneke J, Pudney J, Anderson DJ, Ganem D, et al: Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells. Journal of Virology 1997, 71:715-719
19. Decker LL, Shankar P, Khan G, Freeman RB, Dezube BJ, Lieberman J, Thorley DA-Lawson: The Kaposi sarcoma-associated herpesvirus (KSHV) is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients. Journal of Experimental Medicine 1996, 184:283-288
20. Blasig C, Zietz C, Haar B, Neipel F, Esser S, Brockmeyer NH, Tschachler E, Colombini S, Ensoli B, Sturzl M: Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8. Journal of Virology 1997, 71:7963-7968
21. Moore PS, Boshoff C, Weiss RA, Chang Y: Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 1996, 274:1739-1744
22. Orenstein JM, Alkan S, Blauvelt A, Jeang K-T, Weinstein MD, Ganem D, Herndier B: Visualization of human herpesvirus type 8 in Kaposi's sarcoma by light and transmission electron microscopy. AIDS 1997, 11:F35-F45
23. Kievits T, Van Gemen B, Van Strijp D, Schukkink R, Dircks M, Adriaanse H, Malek L, Sooknanan R, Lens P: NASBA(TM) isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection. Journal of Virological Methods 1991, 35:273-286
24. Heim A, Grumbach IM, Zeuke S, Top B: Highly sensitive detection of gene expression of an intronless gene: Amplification of mRNA, but not genomic DNA by nucleic acid sequence based amplification (NASBA). Nucleic Acids Research 1998, 26:2250-2251
25. Blok MJ, Goossens VJ, Vanherle SJV, Top B, Tacken N, Middeldorp JM, Christiaans MHL, Van Hooff JP, Bruggeman CA: Diagnostic value of monitoring human cytomegalovirus late pp67 mRNA expression in renal-allograft recipients by nucleic acid sequence-based amplification. Journal of Clinical Microbiology 1998, 36:1341-1346
26. Darke BM, Jackson SK, Hanna SM, Fox JD: Detection of human TNF-alpha mRNA by NASBA(TM). Journal of Immunological Methods 1998, 212:19-28
27. Morre SA, Sillekens P, Jacobs MV, van Aarle P, de Blok S, Van Gemen B, Walboomers JM, Meijer CJ, van den Brule AJ: RNA amplification by nucleic acid sequence-based amplification with an internal standard enables reliable detection of Chlamydia trachomatis in cervical scrapings and urine samples. J Clin Microbiol 1996, 34:3108-3114
28. Van Gemen B, Wiel VP, Van Beuningen R, Sillekens P, Jurriaans S, Dries C, Schoones R, Kievits T: The one-tube quantitative HIV-1 RNA NASBA: Precision, accuracy, and application. PCR Methods & Applications 1995, 4:S177-S184
29. Leone G, Van Schijndel H, Van Gemen B, Kramer FR, Schoen CD: Molecular beacon probes combined with amplification by NASBA enable homogeneous, real-time detection of RNA. Nucleic Acids Research 1998, 26:2150-2155
30. Ballestas ME, Chatis PA, Kaye KM: Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen. Science 1999, 284:641-644
31. Cotter MA, Robertson ES: The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells. Virology 1999, 264:254-264
32. Friborg J Jr, Kong W, Hottiger MO, Nabel GJ: p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 1999, 402:889-894
33. Arvanitakis L, Geras-Raaka E, Varma A, Gershengorn MC, Cesarman E: Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation. Nature 1997, 385:347-349
34. Kirshner JR, Staskus K, Haase A, Lagunoff M, Ganem D: Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: Implications for KS pathogenesis. Journal of Virology 1999, 73:6006-6014
35. Bais C, Santomasso B, Coso O, Arvanitakis L, Raaka EG, Gutkind JS, Asch AS, Cesarman E, Gerhengorn MC, Mesri EA: G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 1998, 391:86-89
36. Sarid R, Sato T, Bohenzky RA, Russo JJ, Chang Y: Kaposi's sarcomaassociated herpesvirus encodes a functional Bcl-2 homologue. Nature Medicine 1997, 3:293-298
37. Cheng EHY, Nicholas J, Bellows DS, Hayward GS, Guo H-G, Reitz MS, Hardwick JM: A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Proceedings of the National Academy of Sciences of the United States of America 1997, 94:690-694
38. Nicholas J, Ruvolo VR, Burns WH, Sandford G, Wan X, Ciufo D, Hendrickson SB, Guo H-G, Hayward GS, Reitz MS: Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6. Nature Medicine 1997, 3:287-292
39. Burger R, Neipel F, Fleckenstein B, Savino R, Ciliberto G, Kalden JR, Gramatzki M: Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells. Blood 1998, 91:1858-1863
40. Neipel F, Albrecht J-C, Ensser A, Huang Y-Q, Jian J, Li , Kien AE, Fleckenstein B: Human herpesvirus 8 encodes a homolog of interleukin-6. Journal of Virology 1997, 71:839-842
41. Compton J: Nucleic acid sequence-based amplification. Nature 1991, 350:91-92
42. Tyagi S, Kramer FR: Molecular beacons: Probes that fluoresce upon hybridization. Nature Biotechnology 1996, 14:303-308
43. Higuchi R, Fockler C, Dollinger G, Watson R: Kinetic PCR analysis: Real-time monitoring of DNA amplification reactions. Bio-Technology 1993, 11:1026-1030
44. De Baar MP, van Dooren MW, de Rooij E, Bakker M, Van Gemen B, Goudsmit J, De Ronde A: Single rapid real-time monitored isothermal RNA amplification assay for quantification of human immunodeficiency virus type 1 isolates from groups M, N, and O. J Clin Microbiol 2001, 39:1378-1384
45. Maniatis T, Reed R: The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature 1987, 325:673-678
46. Maxwell ES, Fournier MJ: The small nucleolar RNAs. Annu Rev Biochem 1995, 64:897-934
47. Goudsmit J, Renwick N, Dukers NHTM, Coutinho RA, Heisterkamp S, Bakker M, Schulz TF, Cornelissen M, Weverling GJ: Human herpesvirus 8 infections in the Amsterdam Cohort Studies (1984-1997): Analysis seroconversions to ORF65 and ORF73. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:4838-4843
48. Prins JM, Sol CJA, Renwick N, Goudsmit J, Veenstra J, Reiss P: Favourable effect of chemotherapy on clinical symptoms and human herpesvirus-8 DNA load in a patient with Kaposi's sarcoma presenting with fever and anemia. European Journal of Clinical Microbiology & Infectious Diseases 1999, 18:499-502
49. Wit FWN, Sol CJA, Renwick N, Roos MTL, Pals Van ST, Leeuwen R, Goudsmit J, Reiss P: Regression of AIDS-related Kaposi's sarcoma associated with clearance of human herpesvirus-8 from peripheral blood mononuclear cells following initiation of antiretroviral therapy [2]. AIDS 1998, 12:218-219
50. Campbell TB, Borok M, Gwanzura L, MaWhinney S, White IE, Ndemera B, Gudza I, Fitzpatrick L, Schooley RT: Relationship of human herpesvirus 8 peripheral blood virus load and Kaposi's sarcoma clinical stage. AIDS 2000, 14:2109-2116
51. Romano JW, Shurtliff RN, Dobratz E, Gibson A, Hickman K, Markham PD, Pal R: Quantitative evaluation of simian immunodeficiency virus infection using NASBA technology. J Virol Methods 2000, 86:61-70
52. Fiorelli V, Gendelman R, Sirianni MC, Chang HK, Colombini S, Markham PD, Monini P, Sonnabend J, Pintus A, Gallo RC, et al: gamma-Interferon produced by CD8+ T cells infiltrating Kaposi's sarcoma induces spindle cells with angiogenic phenotype and synergy with human immunodeficiency virus-1 Tat protein: an immune response to human herpesvirus-8 infection? Blood 1998, 91:956-967
53. Sirianni MC, Vincenzi L, Fiorelli V, Topino S, Scala E, Uccini S, Angeloni A, Faggioni A, Cerimele D, Cottoni F, et al: gamma-Interferon production in peripheral blood mononuclear cells and tumor infiltrating lymphocytes from Kaposi's sarcoma patients: correlation with the presence of human herpesvirus-8 in peripheral blood mononuclear cells and lesional macrophages. Blood 1998, 91:968-976
54. Mesri EA, Cesarman E, Arvanitakis L, Rafii S, Moore MA, Posnett DN, Knowles DM, Asch AS: Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells. J Exp Med 1996, 183:2385-2390
55. Sirianni MC, Vincenzi L, Topino S, Scala E, Angeloni A, Gonnella R, Uccini S, Faggioni A: Human herpesvirus 8 DNA sequences in CD8+ T cells. J Infect Dis 1997, 176:541
56. Sirianni MC, Uccini S, Angeloni A, Faggioni A, Cottoni F, Ensoli B: Circulating spindle cells: correlation with human herpesvirus-8 (HHV-8) infection and Kaposi's sarcoma. Lancet 1997, 349:255
57. Ascherl G, Hohenadl C, Monini P, Zietz C, Browning PJ, Ensoli B, Sturzl M: Expression of human herpesvirus-8 (HHV-8) encoded pathogenic genes in Kaposi's sarcoma (KS) primary lesions. Adv Enzyme Regul 1999, 39:331-339
58. Sturzl M, Blasig C, Schreier A, Neipel F, Hohenadl C, Cornali E, Ascherl G, Esser S, Brockmeyer NH, Ekman M, et al: Expression of HHV-8 latency-associated T0.7 RNA in spindle cells and endothelial cells of AIDS-associated, classical and African Kaposi's sarcoma. Int J Cancer 1997, 72:68-71
59. Huang YQ, Li JJ, Zhang WG, Feiner D, Friedman-Kien AE: Transcription of human herpesvirus-like agent (HHV-8) in Kaposi's sarcoma. J Clin Invest 1996, 97:2803-2806
60. Sturzl M, Wunderlich A, Ascherl G, Hohenadl C, Monini P, Zietz C, Browning PJ, Neipel F, Biberfeld P, Ensoli B: Human herpesvirus-8 (HHV-8) gene expression in Kaposi's sarcoma (KS) primary lesions: an in situ hybridization study. Leukemia 1999, 13(Suppl 1):S110-S112
61. Davis MA, Sturzl MA, Blasig C, Schreier A, Guo HG, Reitz M, Opalenik SR, Browning PJ: Expression of human herpesvirus 8-encoded cyclin D in Kaposi's sarcoma spindle cells. J Natl Cancer Inst 1997, 89:1868-1874
62. Luppi M, Barozzi P, Maiorana A, Trovato R, Marasca R, Morselli M, Cagossi K, Torelli G: Expression of cell-homologous genes of human herpesvirus-8 in human immunodeficiency virus-negative lymphoproliferative diseases. Blood 1999, 94:2931-2933