Dual effects of histone deacetylase inhibition by trichostatin A on endothelial nitric oxide synthase expression in endothelial cells

Biochemical and Biophysical Research Communications

Volumn 340, Issue 1, 2006, Pages 29-34

  Gan, Yehua ^a,b   Shen, Ying H ^b   Utama, Budi ^b   Wang, Jian ^b   Coselli, Joseph ^b   Wang, Xing Li ^b  

^a PEKING UNIVERSITY SCHOOL AND HOSPITAL OF STOMATOLOGY   (China)

^b ST LUKE S EPISCOPAL HOSPITAL   (United States)

Author keywords

eNOS; Gene expression; Histone deacetylase; Sp1; TSA

Indexed keywords

COMPACTIN; CYCLOHEXIMIDE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MESSENGER RNA; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; TRICHOSTATIN A;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ENDOTHELIUM CELL; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN MODIFICATION; UPREGULATION;

CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; NITRIC OXIDE SYNTHASE TYPE III;

EID: 29244442918     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.11.151     Document Type: Article

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