메뉴 건너뛰기




Volumn 10, Issue 8, 2005, Pages 780-787

Multiplexed G-protein-coupled receptor Ca2+ flux assays for high-throughput screening

Author keywords

Ca2+ flux; FLIPR; GPCR; HTS; Multiplex

Indexed keywords

CALCIUM ION; G PROTEIN COUPLED RECEPTOR;

EID: 29144533396     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057105279493     Document Type: Article
Times cited : (14)

References (24)
  • 1
    • 4043111826 scopus 로고    scopus 로고
    • G-protein-coupled receptors in drug discovery
    • Nambi P, Aiyar N: G-protein-coupled receptors in drug discovery. Assay Drug Dev Technol 2003;1:305-310.
    • (2003) Assay Drug Dev Technol , vol.1 , pp. 305-310
    • Nambi, P.1    Aiyar, N.2
  • 2
    • 0036240546 scopus 로고    scopus 로고
    • Potassium channels: Gene family, therapeutic relevance, high-throughput screening technologies and drug discovery
    • Ford JW, Stevens EB, Treherne JM, Packer J, Bushfield M: Potassium channels: gene family, therapeutic relevance, high-throughput screening technologies and drug discovery. Prog Drug Res 2002;58:133-168.
    • (2002) Prog Drug Res , vol.58 , pp. 133-168
    • Ford, J.W.1    Stevens, E.B.2    Treherne, J.M.3    Packer, J.4    Bushfield, M.5
  • 3
    • 0035489204 scopus 로고    scopus 로고
    • Reporter-gene systems for the study of G-protein-coupled receptors
    • Hill SJ, Baker JG, Rees S: Reporter-gene systems for the study of G-protein-coupled receptors. Curr Opin Pharmacol 2001;1:526-532.
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 526-532
    • Hill, S.J.1    Baker, J.G.2    Rees, S.3
  • 7
    • 4043107079 scopus 로고    scopus 로고
    • Strategies tor designing GPCR-focused libraries and screening sets
    • Jimonet P, Jager R: Strategies tor designing GPCR-focused libraries and screening sets. Curr Opin Drug Discov Devel 2004;7:325-333.
    • (2004) Curr Opin Drug Discov Devel , vol.7 , pp. 325-333
    • Jimonet, P.1    Jager, R.2
  • 9
    • 0037082324 scopus 로고    scopus 로고
    • Target validation of G-protein coupled receptors
    • Wise A, Gearing K, Rees S: Target validation of G-protein coupled receptors. Drug Discov Today 2002;7:235-246.
    • (2002) Drug Discov Today , vol.7 , pp. 235-246
    • Wise, A.1    Gearing, K.2    Rees, S.3
  • 10
    • 0033151694 scopus 로고    scopus 로고
    • Chimeric G-proteins allow a high-throughput signaling assay of Gi-coupled receptors
    • Coward P, Chan SD, Wada HG, Humphries GM, Conklin BR: Chimeric G-proteins allow a high-throughput signaling assay of Gi-coupled receptors. Anal Biochem 1999;270:242-248.
    • (1999) Anal Biochem , vol.270 , pp. 242-248
    • Coward, P.1    Chan, S.D.2    Wada, H.G.3    Humphries, G.M.4    Conklin, B.R.5
  • 11
    • 0034212465 scopus 로고    scopus 로고
    • Use of a dual firefly and Renilla luciferase reporter gene assay to simultaneously determine drug selectivity at human corticotrophin releasing hormone 1 and 2 receptors
    • Parsons SJ, Rhodes SA, Connor HE, Rees S, Brown J, Giles H: Use of a dual firefly and Renilla luciferase reporter gene assay to simultaneously determine drug selectivity at human corticotrophin releasing hormone 1 and 2 receptors. Anal Biochem 2000;281:187-192.
    • (2000) Anal Biochem , vol.281 , pp. 187-192
    • Parsons, S.J.1    Rhodes, S.A.2    Connor, H.E.3    Rees, S.4    Brown, J.5    Giles, H.6
  • 12
    • 1542648927 scopus 로고    scopus 로고
    • Multiplexing nuclear receptors for agonist identification in a cell-based reporter gene high-throughput screen
    • Grover GS, Turner BA, Parker CN, Meier J, Lala DS, Lee PH: Multiplexing nuclear receptors for agonist identification in a cell-based reporter gene high-throughput screen. J Biomol Screen 2003;8:239-246.
    • (2003) J Biomol Screen , vol.8 , pp. 239-246
    • Grover, G.S.1    Turner, B.A.2    Parker, C.N.3    Meier, J.4    Lala, D.S.5    Lee, P.H.6
  • 13
    • 7044272599 scopus 로고    scopus 로고
    • A novel encoded particle technology that enables simultaneous interrogation of multiple cell types
    • Beske O, Guo J, Li J, Bassoni D, Bland K, Marciniak H, et al: A novel encoded particle technology that enables simultaneous interrogation of multiple cell types. J Biomol Screen 2004;9:173-185.
    • (2004) J Biomol Screen , vol.9 , pp. 173-185
    • Beske, O.1    Guo, J.2    Li, J.3    Bassoni, D.4    Bland, K.5    Marciniak, H.6
  • 14
    • 0041430941 scopus 로고    scopus 로고
    • G-protein-coupled receptor microarrays for drug discovery
    • Fang Y, Lahiri J, Picard L: G-protein-coupled receptor microarrays for drug discovery. Drug Discov Today 2003;8:755-761.
    • (2003) Drug Discov Today , vol.8 , pp. 755-761
    • Fang, Y.1    Lahiri, J.2    Picard, L.3
  • 15
    • 0037020278 scopus 로고    scopus 로고
    • G-protein-coupled receptor microarrays
    • Fang Y, Frutos AG, Lahiri J: G-protein-coupled receptor microarrays, Chembiochem 2002;3:987-991.
    • (2002) Chembiochem , vol.3 , pp. 987-991
    • Fang, Y.1    Frutos, A.G.2    Lahiri, J.3
  • 16
    • 0037107027 scopus 로고    scopus 로고
    • High-throughput cell analysis using multiplexed array technologies
    • Beske OE, Goldbard S: High-throughput cell analysis using multiplexed array technologies. Drug Discov Today 2002;7:S131-135.
    • (2002) Drug Discov Today , vol.7
    • Beske, O.E.1    Goldbard, S.2
  • 17
    • 3142708591 scopus 로고    scopus 로고
    • Simultaneous monitoring of multiple kinase activities by SELDI-TOF mass spectrometry
    • Thulasiramun V, Wang Z, Katrekar A, Lomas L, Yip TT: Simultaneous monitoring of multiple kinase activities by SELDI-TOF mass spectrometry. Methods Mol Biol 2004;264:205-214.
    • (2004) Methods Mol Biol , vol.264 , pp. 205-214
    • Thulasiramun, V.1    Wang, Z.2    Katrekar, A.3    Lomas, L.4    Yip, T.T.5
  • 19
    • 13844286793 scopus 로고    scopus 로고
    • Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader
    • Hodder P, Mull R, Cassaday J, Berry K, Strulovici B: Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader. J Biomol Screen 2004;9:417-426.
    • (2004) J Biomol Screen , vol.9 , pp. 417-426
    • Hodder, P.1    Mull, R.2    Cassaday, J.3    Berry, K.4    Strulovici, B.5
  • 20
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang J-H, Chung TDY, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999;4:67-73.
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.-H.1    Chung, T.D.Y.2    Oldenburg, K.R.3
  • 21
    • 0036493316 scopus 로고    scopus 로고
    • Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1-transformed T cells
    • Yoshie O, Fujisawa R, Nakayama T, Harasawa H, Tago H, Izawa D, et al: Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1-transformed T cells. Blood 2002;99:1505-1511.
    • (2002) Blood , vol.99 , pp. 1505-1511
    • Yoshie, O.1    Fujisawa, R.2    Nakayama, T.3    Harasawa, H.4    Tago, H.5    Izawa, D.6
  • 22
    • 0028015942 scopus 로고
    • Cross-desensitization of receptors for peptide chemoattractants: Characterization of a new form of leukocyte regulation
    • Tomhave ED, Richardson RM, Didsbury JR, Menard L, Snyderman R, Ali H: Cross-desensitization of receptors for peptide chemoattractants: characterization of a new form of leukocyte regulation. J Immunol 1994;153:3267-3275.
    • (1994) J Immunol , vol.153 , pp. 3267-3275
    • Tomhave, E.D.1    Richardson, R.M.2    Didsbury, J.R.3    Menard, L.4    Snyderman, R.5    Ali, H.6
  • 24
    • 0036449330 scopus 로고    scopus 로고
    • The use of biosensors to study GPCR function: Applications for high-content screening
    • Conway BR, Dentarest KT: The use of biosensors to study GPCR function: applications for high-content screening. Recept Channels 2002;8:331-341.
    • (2002) Recept Channels , vol.8 , pp. 331-341
    • Conway, B.R.1    Dentarest, K.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.