Rapid, transient phosphatidylserine externalization induced in host cells by infection with Chlamydia spp.

Infection and Immunity

Volumn 69, Issue 2, 2001, Pages 1109-1119

  Goth, S R ^a   Stephens, R S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLSERINE;

ARTICLE; ATHEROSCLEROSIS; BLOOD CLOTTING; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; EPITHELIUM CELL; GENITAL TRACT INFECTION; GRANULOCYTE; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PATHOGENESIS; PHAGOCYTOSIS; PRIORITY JOURNAL; TRACHOMA;

APOPTOSIS; BACTERIAL ADHESION; BLOOD COAGULATION; CELL LINE; CHLAMYDIA INFECTIONS; ENDOTHELIUM, VASCULAR; HUMANS; MACROPHAGES; MONOCYTES; NEUTROPHILS; PHOSPHATIDYLSERINES;

EID: 0035145512     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.2.1109-1119.2001     Document Type: Article

References (70)

1. Thrombin activates nuclear factor kB and potentiates endothelial cell activation by TNF
2. Oxysterols induce membrane procoagulant activity in monocytic THP1 cells
3. The significance of shed membrane particles during programmed cell death in vitro, and in vivo, in HIV-1 infection
4. Role of neutrophils in controlling early stages of a Chlamydia trachornatis infection
5. Fibrinogen in human atherosclerosis
6. Chlamydia trachomatis serovar L2 induces protein tyrosine phosphorylation during uptake by HeLa cells
7. Apoptotic vascular endothelial cells become procoagulant
8. Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by the loss of the aminophospholipid translocase
9. Phagocytosis triggers macrophage release of Fas ligand and induces apoptosis of bystander leukocytes
10. Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in systemic lupus erythematosus
11. Chlamydia trachomatis genital infections - United States, 1995
12. Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin
13. Inflammation and repair
14. Physiopathological significance of catalytic phospholipids in the generation of thrombin
15. Role of translocases in the generation of phosphatidylserine asymmetry
16. Preparation and characterization of an endogenously fluorescent annexin for detection of apoptotic cells
17. 2, and PAF
18. CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha V beta3)
19. Inhibition of apoptosis in Chlamydia-infected cells: Blockade of mitochondrial cytochrome c release and caspase activation
20. Infection with Chlamydia trachomatis alters the tyrosine phosphorylation and/or localization of several host cell proteins including cortactin
21. Chlamydia species infect human vascular endothelial cells and induce procoagulant activity
22. Co-expression of Fas and Fas-ligand on the surface of influenza virus-infected cells
23. Apoptosis in macrophages and alveolar epithelial cells during early stages of infection by Legionella pneumophilia and its role in cytopathogenicity
24. Replication of Chlamydia pneumoniae in vitro in human macrophages, endothelial cells, and aortic smooth muscle cells
25. Induction of apoptosis by Chlamydia psittaci and Chlamydia trachomatis infection in tissue culture cells
26. Other functions, other genes: Alternative activation of antigen-presenting cells
27. New knowledge of chlamydiae and the diseases they cause
28. Chlamydiae pneumoniae, strain TWAR pneumoniae
29. Granulocyte apoptosis and inflammatory disease
30. Staining of nonviable cells with 7-aminoactinomycin for dead-cell discrimination
31. Thrombosis and atherosclerosis
32. Platelet adhesion to aortic endothelial cells in vitro after thrombin treatment: Observation with video-enhanced contrast microscopy
33. Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106)
34. Relationship between tissue factor expression and deposition of fibrin, platelets, and leukocytes on cultured endothelial cells under venous flow condions
35. Host response
36. Endovascular presence of viable Chlamydia pneumoniae is a common phenomenon in coronary artery disease
37. 2+ and F-actin in intracellular aggregation of Chlamydia trachomatis in eucaryotic cells
38. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of BCL-2 and Abl
39. Complement-dependent clearance of apoptotic cells by human macrophages
40. Interaction of Chlamydia and host cells in vitro
41. Retinoic acid inhibits lipopolysaccharide induction of tissue factor gene expression in human monocytes
42. Apoptosis of epithelial cells and macrophages due to infection with the obligate intracellular pathogen Chlamydia psittaci
43. In vivo uptake of Chlamydia trachomatis by Fallopian tube epithelial cells is rapid
44. Effects of the serine analogues isoserine and serinol on interleukin-2 synthesis and phospholipid metabolism in a human T cell line Jurkat
45. CD47 signals T cell death
46. Phosphatidylserine-mediated adhesion of T-cells to endothelial cells
47. Isolation of Chlamydia pneumoniae from the coronary artery of a patient with coronary atherosclerosis
48. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis
49. Interaction between Chlamydia spp. and human polymorphonuclear leukocytes in vitro
50. Endotoxin enhances the expression of monocyte prothrombinase activity
51. Immunogenicity of apoptotic cells in vivo: Role of antigen load, antigen-presenting cells, and cytokine
52. Atherosclerosis - An inflammatory disease
53. Structural biology of tissue factor, the initiator of thrombogenesis in vivo
54. Serological evidence of an association of a novel Chlamydia, TWAR, with chronic heart disease and acute myocardial infarction
55. Macrophage phagocytosis of aging neutrophils in inflammation
56. Recognition and phagocytosis of cells undergoing apoptosis
57. Chlamydial infections
58. Dead cell discrimination with 7-aminoactinomycin D in combination with dual color immunofluorescence in single laser flow cytometry
59. The effect of ions on the adhesion and internalization of Chlamydia trachomatis by HeLa cells
60. Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: A mechanism for stabilizing neutrophil adhesion
61. Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis
62. Annexin V-affinity assay: A review of an apoptosis detection system based on phosphatidylserine exposure
63. Chlamydia trachomatis infection of human mesothelial cells alters proinflammatory, procoagulant, and fibrinolytic responses
64. Immunosuppressive effects of apoptotic cells
65. Activation of the alternative complement pathway by exposure of phosphatidylethanolamine and phosphatidylserine on erythrocytes from sickle cell disease patients
66. Apoptosis: An overview
67. Toxic effect of human polymorphonuclear leukocytes on Chlamydia trachomatis
68. Mechanism of C. trachomatis attachment to eukaryotic host cells
69. Dissociation of phagocyte recognition of cells undergoing apoptosis from other features of the apoptotic program
70. Pathophysiological implications of membrane phospholipid asymmetry in blood cells