Human growth hormone 1 (GH1) gene expression: Complex haplotype-dependent influence of polymorphic variation in the proximal promoter and locus control region

Human Mutation

Volumn 21, Issue 4, 2003, Pages 408-423

  Horan, Martin ^a   Millar, David S ^a   Hedderich, Jürgen ^b   Lewis, Geraint ^a   Newsway, Vicky ^a   Mo, Neil ^a   Fryklund, Linda ^c   Procter, Annie M ^a   Krawczak, Michael ^b   Cooper, David N ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF KIEL   (Germany)

^c PFIZER INC   (United States)

Author keywords

Evolution; Expression; GH1; Growth hormone; Haplotype partitioning; Haplotypes; Linkage disequilibrium; Locus control region; Polymorphism; Promoter; Short stature; SNP; Transcription factor binding

Indexed keywords

HUMAN GROWTH HORMONE;

ARTICLE; BODY HEIGHT; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE; GENE ACTIVITY; GENE EXPRESSION; GENETIC VARIABILITY; GROWTH HORMONE 1 GENE; HAPLOTYPE; HUMAN; HUMAN CELL; MALE; NUCLEOTIDE SEQUENCE; POPULATION GENETICS; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REGULATOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; BODY HEIGHT; CHROMOSOME MAPPING; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EUROPEAN CONTINENTAL ANCESTRY GROUP; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE FREQUENCY; GREAT BRITAIN; GROWTH DISORDERS; HAPLOTYPES; HUMAN GROWTH HORMONE; HUMANS; LINKAGE DISEQUILIBRIUM; LOCUS CONTROL REGION; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; PROMOTER REGIONS (GENETICS); VARIATION (GENETICS);

EID: 0037240296     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.10167     Document Type: Article

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