Molecular basis for nucleotide-binding specificity: Role of the exocyclic amino group "N2" in recognition by a guanylyl-ribonuclease

Journal of Molecular Biology

Volumn 355, Issue 1, 2006, Pages 72-84

  Schrift, Greta L ^a,b   Waldron, Travis T ^a,c   Timmons, Mitchell A ^a   Ramaswamy, S ^a   Kearney, William R ^a   Murphy, Kenneth P ^a  

^a UNIVERSITY OF IOWA   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calorimetry; Guanosine; Heat capacity; Inosine; Nucleotide binding

Indexed keywords

GLUTAMIC ACID; GUANINE NUCLEOTIDE; GUANOSINE 3' PHOSPHATE; INOSINE 3' MONOPHOSPHATE; INOSINE PHOSPHATE; PHOSPHATE; RIBONUCLEASE; RIBONUCLEASE T1; SUGAR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; CRYSTAL STRUCTURE; ENTHALPY; ENZYME STRUCTURE; HEAT; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; RIBONUCLEASE SA; SIMULATION; STREPTOMYCES AUREOFACIENS; X RAY CRYSTALLOGRAPHY;

STREPTOMYCES AUREOFACIENS;

EID: 28844491827     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.10.019     Document Type: Article

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