Genotoxicity evaluation of kaurenoic acid, a bioactive diterpenoid present in Copaiba oil

Food and Chemical Toxicology

Volumn 44, Issue 3, 2006, Pages 388-392

  Cavalcanti, B C ^a   Costa Lotufo, L V ^a   Moraes, M O ^a   Burbano, R R ^b   Silveira, E R ^a   Cunha, K M A ^a   Rao, V S N ^a   Moura, D J ^c   Rosa, R M ^c   Henriques, J A P ^c   Pessoa, C ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF PARÁ   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Comet assay; In vitro genotoxicity; Kaurenoic acid; Micronucleus test; Plant diterpene

Indexed keywords

DITERPENOID; KAURENOIC ACID; MESYLIC ACID METHYL ESTER; VEGETABLE OIL;

ANIMAL CELL; ARTICLE; CELL DAMAGE; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COPAIFERA LANGSDORFFII; CYTOTOXICITY; GENOTOXICITY; HAMSTER; LUNG FIBROBLAST; MEDICINAL PLANT; MICRONUCLEUS TEST; NONHUMAN; TOXICITY TESTING;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; COMET ASSAY; CRICETINAE; CRICETULUS; DITERPENES; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FABACEAE; LUNG NEOPLASMS; METHYL METHANESULFONATE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; PHYTOTHERAPY; PLANT EXTRACTS; TUMOR CELLS, CULTURED;

ANIMALIA; COPAIFERA LANGSDORFFII; COPAIFERA OFFICINALIS; CRICETINAE; CRICETULUS GRISEUS;

EID: 28844441957     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.08.011     Document Type: Article

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