A prostanoid receptor EP4 agonist enhances ectopic bone formation induced by recombinant human bone morphogenetic protein-2

Biochemical and Biophysical Research Communications

Volumn 318, Issue 3, 2004, Pages 704-709

  Sasaoka, Ryuichi ^a   Terai, Hidetomi ^a   Toyoda, Hiromitsu ^a   Imai, Yuuki ^a   Sugama, Ryo ^a   Takaoka, Kunio ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

BMP; Bone formation; Bone morphogenetic protein; EP4 agonist; Mesenchymal cell; Osteoblast; Prostaglandins

Indexed keywords

7 [3 HYDROXY 2 [3 HYDROXY 4 (3 METHOXYMETHYLPHENYL) 1 BUTENYL] 5 OXOCYCLOPENTYL] 5 THIAHEPTANOIC ACID METHYL ESTER; BONE MORPHOGENETIC PROTEIN 2; HEPTANOIC ACID DERIVATIVE; PROSTANOID; PROSTANOID RECEPTOR; RECOMBINANT HUMAN BONE MORPHOGENIC PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE DENSITY; BONE MINERAL; CONTROLLED STUDY; DRUG EFFECT; DRUG SELECTIVITY; HUMAN; MALE; MESENCHYME; MOUSE; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL;

ABSORBABLE IMPLANTS; ALKALINE PHOSPHATASE; ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE MORPHOGENETIC PROTEINS; COLLAGEN; DENSITOMETRY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; HEPTANOATES; HUMANS; MALE; MICE; MICE, INBRED ICR; OSTEOCALCIN; OSTEOGENESIS; RECEPTORS, PROSTAGLANDIN E; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 2442537090     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.04.080     Document Type: Article

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