The lipolytic proteome of mouse adipose tissue

Molecular and Cellular Proteomics

Volumn 4, Issue 11, 2005, Pages 1710-1717

  Birner Gruenberger, Ruth ^a   Susani Etzerodt, Heidrun ^a   Waldhubert, Markus ^a   Riesenhubert, Gernot ^a   Schmidinger, Hannes ^a   Rechberger, Gerald ^b   Kollroser, Manfred ^c   Strauss, Juliane G ^b   Lass, Achim ^b   Zimmermann, Robert ^b   Haemmerle, Guenter ^b   Zechner, Rudolf ^b   Hermetter, Albin ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b UNIVERSITY OF GRAZ   (Austria)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

TRIACYLGLYCEROL LIPASE;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; LIPOLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

4-CHLORO-7-NITROBENZOFURAZAN; ADIPOSE TISSUE; ANIMALS; CHOLESTEROL ESTERASE; LIPASE; LIPOLYSIS; MICE; MICE, KNOCKOUT; PROTEOME;

ANIMALIA;

EID: 28644432203     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.M500062-MCP200     Document Type: Article

References (50)

1. Bergman, R. N., Van Citters, G. W., Mittelman, S. D., Dea, M. K., Hamilton-Wessler, M., Kim, S. P., and Ellmerer, M. (2001) Central role of the adipocyte in the metabolic syndrome. J. Investig. Med. 49, 119-126
2. Arner, P. (2002) Insulin resistance in type 2 diabetes: role of fatty acids. Diabetes Metab. Res. Rev. 18, Suppl. 2, S5-S9
3. Boden, G., and Shulman, G. I. (2002) Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur. J. Clin. Investig. 32, Suppl. 3, 14-23
4. Blaak, E. E. (2003) Fatty acid metabolism in obesity and type 2 diabetes mellitus. Proc. Nutr. Soc. 62, 753-760
5. Semeriva, M., and Desnuelle, P. (1979) Pancreatic lipase and colipase. An example of heterogeneous biocatalysis. Adv. Enzymol. Relat. Areas Mol. Biol. 48, 319-370
6. Preiss-Landl, K., Zimmermann, R., Hammerle, G., and Zechner, R. (2002) Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism. Curr. Opin. Lipidol. 13, 471-481
7. Thuren, T. (2000) Hepatic lipase and HDL metabolism. Curr. Opin. Lipidol. 11, 277-283
8. McCoy, M. G., Sun, G. S., Marchadier, D., Maugeais, C., Glick, J. M., and Rader, D. J. (2002) Characterization of the lipolytic activity of endothelial lipase. J. Lipid Res. 43, 921-929
9. Kraemer, F. B., and Shen, W. J. (2002) Hormone-sensitive lipase: control of intracellular tri-(di-)acylglycerol and cholesteryl ester hydrolysis. J. Lipid Res. 43, 1585-1594
10. Karlsson, M., Contreras, J. A., Hellman, U., Tornqvist, H., and Holm, C. (1997) cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases. J. Biol. Chem. 272, 27218-27223
11. Dolinsky, V. W., Sipione, S., Lehner, R., and Vance, D. E. (2001) The cloning and expression of a murine triacylglycerol hydrolase cDNA and the structure of its corresponding gene. Biochim. Biophys. Acta 1532, 162-172
12. Gilham, D., Alam, M., Gao, W., Vance, D. E., and Lehner, R. (2005) Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates. Mol. Biol. Cell 16, 984-996
13. Cravatt, B. F., and Sorensen, E. J. (2000) Chemical strategies for the global analysis of protein function. Curr. Opin. Chem. Biol. 4, 663-668
14. Adam, G. C., Sorensen, E. J., and Cravatt, B. F. (2002) Chemical strategies for functional proteomics. Mol. Cell. Proteomics 1, 781-790
15. Campbell, D. A., and Szardenings, A. K. (2003) Functional profiling of the proteome with affinity labels. Curr. Opin. Chem. Biol. 7, 296-303
16. Speers, A. E., and Cravatt, B. F. (2004) Chemical strategies for activity-based proteomics. ChemBioChem 5, 41-47
17. Cygler, M., Grochulski, P., Kazlauskas, R. J., Schrag, J. D., Bouthillier, F., Rubin, B., Serreqi, A. N., and Gupta, A. K. (2004) A structural basis for the chiral preferences of lipases. J. Am. Chem. Soc. 116, 3180-3186
18. Ollis, D. L., Cheah, E., Cygler, M., Dijkstra, B., Frolow, F., Franken, S. M., Harel, M., Remington, S. J., Silman, I., and Schrag, J. (1992) The α/β hydrolase fold. Protein Eng. 5, 197-211
19. Schrag, J. D., and Cygler, M. (1997) Lipases and α/β hydrolase fold. Methods Enzymol. 284, 85-107
20. Patricelli, M. P., Giang, D. K., Stamp, L. M., and Burbaum, J. J. (2001) Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes. Proteomics 1, 1067-1071
21. Jessani, N., Liu, Y., Humphrey, M., and Cravatt, B. F. (2002) Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness. Proc. Natl. Acad. Sci. U. S. A. 99, 10335-10340
22. Baxter, S. M., Rosenblum, J. S., Knutson, S., Nelson, M. R., Montimurro, J. S., Di Gennaro, J. A., Speir, J. A., Burbaum, J. J., and Fetrow, J. S. (2004) Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol. Cell. Proteomics 3, 209-225
23. Oskolkova, O. V., Saf, R., Zenzmaier, E., and Hermetter, A. (2003) Fluorescent organophosphonates as inhibitors of microbial lipases. Chem. Phys. Lipids 125, 103-114
24. Scholze, H., Stutz, H., Paltauf, F., and Hermetter, A. (1999) Fluorescent inhibitors for the qualitative and quantitative analysis of lipolytic enzymes. Anal. Biochem. 276, 72-80
25. Birner-Grunberger, R., Scholze, H., Faber, K., and Hermetter, A. (2004) Identification of various lipolytic enzymes in crude porcine pancreatic lipase preparations using covalent fluorescent inhibitors. Biotechnol. Bioeng. 85, 147-154
26. Haemmerle, G., Zimmermann, R., Hayn, M., Theussl, C., Waeg, G., Wagner, E., Sattler, W., Magin, T. M., Wagner, E. F., and Zechner, R. (2002) Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis. J. Biol. Chem. 277, 4806-4815
27. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
28. Fling, S. P., and Gregerson, D. S. (1986) Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea. Anal. Biochem. 155, 83-88
29. Gorg, A., Postel, W., Gunther, S., and Weser J. (1985) Improved horizontal two-dimensional electrophoresis with hybrid isoelectric-focusing in immobilized pH gradients in the 1st-dimension and laying-on transfer to the 2nd-dimension. Electrophoresis 6, 599-604
30. Gorg, A., Postel, W., and Gunther, S. (1988) The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 9, 531-546
31. Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. (1996) Mass spectrometric sequencing of proteins from silver stained polyacrylamide gels. Anal. Chem. 68, 850-858
32. Carr, S., Aebersold, R., Baldwin, M., Burlingame, A., Clauser, K., and Nesvizhskii, A. (2004) The need for guidelines in publication of peptide and protein identification data. Working Group on Publication Guidelines for Peptide and Protein Identification Data. Mol. Cell. Proteomics 3, 531-533
33. Zimmermann, R., Strauss, J. G., Haemmerle, G., Schoiswohl, G., Birner-Gruenberger, R., Riederer, M., Lass, A., Neuberger, G., Eisenhaber, F., Hermetter, A., and Zechner, R. (2004) Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 306, 1383-1386
34. Lehner, R., and Verger, R. (1997) Purification and characterization of a porcine liver microsomal triacylglycerol hydrolase. Biochemistry (Mosc.) 36, 1861-1868
35. Shirai, K., and Jackson, R. L. (1982) Lipoprotein lipase-catalyzed hydrolysis of p-nitrophenyl butyrate. Interfacial activation by phospholipid vesicles. J. Biol. Chem. 257, 1253-1258
36. Holm, C., Olivecrona, G., and Ottosson, M. (2001) Assays of lipolytic enzymes. Methods Mol. Biol. 155, 97-119
37. Wang, A., Deems, R. A., and Dennis, E. A. (1997) Cloning, expression, and catalytic mechanism of murine lysophospholipase I. J. Biol. Chem. 272, 12723-12729
38. Zhang, Y. Y., and Dennis, E. A. (1988) Purification and characterization of a lysophospholipase from a macrophage-like cell line P388D1. J. Biol. Chem. 263, 9965-9972
39. Leung, D., Hardouin, C., Boger, D. L., and Cravatt, B. F. (2003) Discovering potent and selective reversible inhibitors of enzymes in complex proteomes. Nat. Biotechnol. 21, 687-691
40. Nagamine, K., Kudoh, J., Minoshima, S., Kawasaki, K., Asakawa, S., Ito, F., and Shimizu, N. (1996) Isolation of cDNA for a novel human protein KNP-I that is homologous to the E. coli SCRP-27A protein from the autoimmune polyglandular disease type I (APECED) region of chromosome 21q22.3. Biochem. Biophys. Res. Commun. 225, 608-616
41. Lee, W. H., Wheatley, W., Benedict, W. F., Huang, C. M., and Lee, E. Y. (1986) Purification, biochemical characterization, and biological function of human esterase D. Proc. Natl. Acad. Sci. U. S. A. 83, 6790-6794
42. Lee, E. Y., and Lee, W. H. (1986) Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma. Proc. Natl. Acad. Sci. U. S. A. 83, 6337-6341
43. Merla, G., Ucla, C., Guipponi, M., and Reymond, A. (2002) Identification of additional transcripts in the Williams-Beuren syndrome critical region. Hum. Genet. 110, 429-438
44. Lefevre, C., Jobard, F., Caux, F., Bouadjar, B., Karaduman, A., Heilig, R., Lakhdar, H., Wollenberg, A., Verret, J. L., Weissenbach, J., Ozguc, M., Lathrop, M., Prud'homme, J. F., and Fischer J. (2001) Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome. Am. J. Hum. Genet. 69, 1002-1012
45. Ogris, E., Du, X., Nelson, K. C., Mak, E. K., Yu, X. X., Lane, W. S., and Pallas, D. C. (1999) A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A. J. Biol. Chem. 274, 14382-14391
46. Jones, W. M., Scaloni, A., Bossa, F., Popowicz, A. M., Schneewind, O., and Manning, J. M. (1991) Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities. Proc. Natl. Acad. Sci. U. S. A. 88, 2194-2198
47. Kobayashi, K., Lin, L. W., Yeadon, J. E., Klickstein, L. B., and Smith, J. A. (1989) Cloning and sequence analysis of a rat liver cDNA encoding acyl-peptide hydrolase. J. Biol. Chem. 264, 8892-8899
48. Sakurai, Y., Ma, S. F., Watanabe, H., Yamaotsu, N., Hirono, S., Kurono, Y., Kragh-Hansen, U., and Otagiri, M. (2004) Esterase-like activity of serum albumin: characterization of its structural chemistry using p-nitrophenyl esters as substrates. Pharm. Res. 21, 285-292
49. Laurin, N. N., Wang, S. P., and Mitchell, G. A. (2000) The hormone-sensitive lipase gene is transcribed from at least five alternative first exons in mouse adipose tissue. Mamm. Genome 11, 972-978
50. Schmidinger, H., Birner-Gruenberger, R., Riesenhuber, G., Susani-Etzerodt, H., Saf, R., and Hermetter, A. (2005) Novel fluorescent phosphonic acid esters for discrimination of lipases and esterases. ChemBioChem, in press