Comparison of covalent with reversible inhibitor binding sites of the gastric H,K-ATPase by site-directed mutagenesis

Journal of Biological Chemistry

Volumn 275, Issue 6, 2000, Pages 4041-4048

  Lambrecht, Nils ^b   Munson, Keith ^b   Vagin, Olga ^b   Sachs, George ^a,b  

^a Vet Aff Gtr Los Angeles Hlth C ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; OMEPRAZOLE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; KIDNEY CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTON TRANSPORT; RABBIT; SITE DIRECTED MUTAGENESIS;

ANTI-ULCER AGENTS; BINDING SITES; CELL LINE; ENZYME INHIBITORS; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; HUMANS; IMIDAZOLES; KINETICS; MICROSCOPY, CONFOCAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; MUTATION; OMEPRAZOLE; PROTEIN STRUCTURE, SECONDARY; QUATERNARY AMMONIUM COMPOUNDS;

ORYCTOLAGUS CUNICULUS;

EID: 0034635518     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.6.4041     Document Type: Article

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