Immunosuppressive effects of surgery assessed by flow cytometry in nonhuman primates after nephrectomy

Transplant International

Volumn 18, Issue 10, 2005, Pages 1158-1165

  Stalder, Mario ^a   Bîrsan, Tudor ^a   Hausen, Bernard ^a   Borie, Dominic C ^a   Morris, Randall E ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Cytokines; Immunosuppression; Lymphocytes; Proliferation; Surgery; T cells

Indexed keywords

CD71 ANTIGEN; CELL NUCLEUS ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MEMBRANE ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; BLOOD; BLOOD SAMPLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE PROLIFERATION; MAJOR SURGERY; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PRIMATE; PRIORITY JOURNAL; SURGICAL TECHNIQUE; T LYMPHOCYTE; UNINEPHRECTOMY;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD3; CELL PROLIFERATION; FLOW CYTOMETRY; IMMUNE TOLERANCE; IMMUNOSUPPRESSION; INTERFERON TYPE II; INTERLEUKIN-2; LIVER; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MACACA FASCICULARIS; MALE; NEPHRECTOMY; PRIMATES; RECEPTORS, INTERLEUKIN-2; RECEPTORS, TRANSFERRIN; T-LYMPHOCYTES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 28444471612     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2005.00119.x     Document Type: Article

References (34)

1. Slade MS, Simmons RL, Yunis E, Greenberg LJ. Immunodepression after major surgery in normal patients. Surgery 1975; 78: 363.
2. Ichihara F, Kono K, Sekikawa T, Matsumoto Y. Surgical stress induces decreased expression of signal-transducing zeta molecules in T cells. Eur Surg Res 1999; 31: 138.
3. Ogawa K, Hirai M, Katsube T, et al. Suppression of cellular immunity by surgical stress. Surgery 2000; 127: 329.
4. Hensler T, Hecker H, Heeg K, et al. Distinct mechanisms of immunosuppression as a consequence of major surgery. Infect Immun 1997; 65: 2283.
5. Lennard TW, Shenton BK, Borzotta A, et al. The influence of surgical operations on components of the human immune system. Br J Surg 1985; 72: 771.
6. Leung KL, Lai PB, Ho RL, et al. Systemic cytokine response after laparoscopic-assisted resection of rectosigmoid carcinoma: a prospective randomized trial. Ann Surg 2000; 231: 506.
7. Brune IB, Wilke W, Hensler T, Holzmann B, Siewert JR. Downregulation of T helper type 1 immune response and altered pro-inflammatory and anti-inflammatory T cell cytokine balance following conventional but not laparoscopic surgery. Am J Surg 1999; 177: 55.
8. Decker D, Schondorf M, Bidlingmaier F, Hirner A, von Ruecker AA. Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma. Surgery 1996; 119: 316.
9. Griffith JP, Everitt NJ, Lancaster F, et al. Influence of laparoscopic and conventional cholecystectomy upon cell-mediated immunity. Br J Surg 1995; 82: 677.
10. Little D, Regan M, Keane RM, Bouchier-Hayes D. Peri-operative immune modulation. Surgery 1993; 114: 87.
11. Allendorf JD, Bessler M, Whelan RL, et al. Postoperative immune function varies inversely with the degree of surgical trauma in a murine model. Surg Endosc 1997; 11: 427.
12. Gummert JF, Barten MJ, van Gelder T, Billingham ME, Morris RE. Pharmacodynamics of mycophenolic acid in heart allograft recipients: correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology. Transplantation 2000; 70: 1038.
13. Barten MJ, Gummert JF, van Gelder T, Shorthouse R, Morris RE. Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro. J Immunol Methods 2001; 253: 95.
14. Dambrin C, Klupp J, Morris RE. Pharmacodynamics of immunosuppressive drugs. Curr Opin Immunol 2000; 12: 557.
15. Thompson SC, Bowen KM, Burton RC. Sequential monitoring of peripheral blood lymphocyte subsets in rats. Cytometry 1986; 7: 184.
16. Oka M, Hirazawa K, Yamamoto K, et al. Induction of Fas-mediated apoptosis on circulating lymphocytes by surgical stress. Ann Surg 1996; 223: 434.
17. Delogu G, Moretti S, Antonucci A, et al. Apoptosis and surgical trauma: dysregulated expression of death and survival factors on peripheral lymphocytes. Arch Surg 2000; 135: 1141.
18. Delogu G, Moretti S, Famularo G, et al. Mitochondrial perturbations and oxidant stress in lymphocytes from patients undergoing surgery and general anesthesia. Arch Surg 2001; 136: 1190.
19. Faist E, Schinkel C, Zimmer S. Update on the mechanisms of immune suppression of injury and immune modulation. World J Surg 1996; 20: 454.
20. Horgan AF, Mendez MV, O'Riordain DS, Holzheimer RG, Mannick JA, Rodrick ML. Altered gene transcription after burn injury results in depressed T-lymphocyte activation. Ann Surg 1994; 220: 342.
21. Huebers HA, Finch CA. The physiology of transferrin and transferrin receptors. Physiol Rev 1987; 67: 520.
22. Pattanapanyasat K, Hoy TG. Expression of cell surface transferrin receptor and intracellular ferritin after in vitro stimulation of peripheral blood T lymphocytes. Eur J Haematol 1991; 47: 140.
23. Salmeron A, Borroto A, Fresno M, Crumpton MJ, Ley SC, Alarcon B. Transferrin receptor induces tyrosine phosphorylation in T cells and is physically associated with the TCR zeta-chain. J Immunol 1995; 154: 1675.
24. Truneh A, Albert F, Golstein P, Schmitt-Verhulst AM. Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester. Nature 1985; 313: 318.
25. Douziech N, Seres I, Larbi A, et al. Modulation of human lymphocyte proliferative response with aging. Exp Gerontol 2002; 37: 369.
26. Lee KY, Koh DK, Lee JS, Whang KT. Varying effects of intravenous immunoglobulin on mononuclear cell proliferation in vitro. J Korean Med Sci 2001; 16: 544.
27. Kiessling R, Wasserman K, Horiguchi S, et al. Tumor-induced immune dysfunction. Cancer Immunol Immunother 1999; 48: 353.
28. Gummert JF, Otto G, Barten MJ, Morris RE. Effect of anesthesia on a whole blood lymphocyte proliferation assay in the rat. Immunopharmacol Immunotoxicol 1999; 21: 267.
29. Thomas J, Carver M, Haisch C, Thomas F, Welch J, Carchman R. Differential effects of intravenous anaesthetic agents on cell-mediated immunity in the rhesus monkey. Clin Exp Immunol 1982; 47: 457.
30. Roy S, Loh HH. Effects of opioids on the immune system. Neurochem Res 1996; 21: 1375.
31. Eisenstein TK, Hilburger ME. Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations. J Neuroimmunol 1998; 83: 36.
32. Gomez-Flores R, Weber RJ. Inhibition of interleukin-2 production and downregulation of IL-2 and transferrin receptors on rat splenic lymphocytes following PAG morphine administration: a role in natural killer and T cell suppression. J Interferon Cytokine Res 1999; 19: 625.
33. Suzuki S, Miyagi T, Chuang TK, Chuang LF, Doi RH, Chuang RY. Morphine upregulates mu opioid receptors of human and monkey lymphocytes. Biochem Biophys Res Commun 2000; 279: 621.
34. Wang J, Charboneau R, Balasubramanian S, Barke RA, Loh HH, Roy S. Morphine modulates lymph node-derived T lymphocyte function: role of caspase-3, -8, and nitric oxide. J Leukoc Biol 2001; 70: 527.