-
1
-
-
0036312080
-
Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter
-
BAN, N., YAMADA, Y., SOMEYA, Y., MIYAWAKI, K., IHARA, Y., HOSOKAWA, M., TOYOKUNI, S., TSUDA, K., and SEINO, Y. (2002). Hepatocyte nuclear factor-1alpha recruits the transcriptional co-activator p300 on the GLUT2 gene promoter. Diabetes 51, 1409-1418.
-
(2002)
Diabetes
, vol.51
, pp. 1409-1418
-
-
Ban, N.1
Yamada, Y.2
Someya, Y.3
Miyawaki, K.4
Ihara, Y.5
Hosokawa, M.6
Toyokuni, S.7
Tsuda, K.8
Seino, Y.9
-
2
-
-
0034731286
-
MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X)
-
BJØRKHAUG, L., YE, H., HORIKAWA, Y., SØVIK, O., MOLVEN, A., and NJØLSTAD, P.R. (2000). MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X). Biochem. Biophys. Res. Commun. 279, 792-798.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.279
, pp. 792-798
-
-
Bjørkhaug, L.1
Ye, H.2
Horikawa, Y.3
Søvik, O.4
Molven, A.5
Njølstad, P.R.6
-
3
-
-
0037323369
-
Hepatocyte nuclear factor-1 alpha gene mutations and diabetes in Norway
-
BJØRKHAUG, L., SAGEN, J.V., THORSBY, P., SØVIK, O., MOLVEN, A., and NJØLSTAD, P.R. (2003). Hepatocyte nuclear factor-1 alpha gene mutations and diabetes in Norway. J. Clin. Endocrinol. Metab. 88, 920-931.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 920-931
-
-
Bjørkhaug, L.1
Sagen, J.V.2
Thorsby, P.3
Søvik, O.4
Molven, A.5
Njølstad, P.R.6
-
4
-
-
0035807902
-
A transcription factor regulatory circuit in differentiated pancreatic cells
-
BOJ, S.F., PARRIZAS, M., MAESTRO, M.A., and FERRER, J. (2001). A transcription factor regulatory circuit in differentiated pancreatic cells. Proc. Natl. Acad. Sci. USA 98, 14481-14486.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14481-14486
-
-
Boj, S.F.1
Parrizas, M.2
Maestro, M.A.3
Ferrer, J.4
-
5
-
-
0028287515
-
Putative nuclear localization signals (NLS) in protein transcription factors
-
BOULIKAS, T. (1994). Putative nuclear localization signals (NLS) in protein transcription factors. J. Cell. Biochem. 55, 32-58.
-
(1994)
J. Cell. Biochem.
, vol.55
, pp. 32-58
-
-
Boulikas, T.1
-
6
-
-
0033782013
-
To be or not to be in the nucleolus
-
CARMO-FONSECA, M., MENDES-SOARES, L., and CAMPOS, I. (2000). To be or not to be in the nucleolus. Nat. Cell Biol. 2, E107-E112.
-
(2000)
Nat. Cell Biol.
, vol.2
-
-
Carmo-Fonseca, M.1
Mendes-Soares, L.2
Campos, I.3
-
7
-
-
0028839631
-
Nuclear localization signals, DNA binding, and transactivation properties of quail Pax-6 (Pax-QNR) isoforms
-
CARRIERE, C., PLAZA, S., CABOCHE, J., DOZIER, C., BAILLY, M., MARTIN, P., and SAULE, S. (1995). Nuclear localization signals, DNA binding, and transactivation properties of quail Pax-6 (Pax-QNR) isoforms. Cell Growth Differ. 6, 1531-1540.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 1531-1540
-
-
Carriere, C.1
Plaza, S.2
Caboche, J.3
Dozier, C.4
Bailly, M.5
Martin, P.6
Saule, S.7
-
8
-
-
0029962261
-
Liver-enriched transcription factors and hepatocyte differentiation
-
CEREGHINI, S. (1996). Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10, 267-282.
-
(1996)
FASEB J.
, vol.10
, pp. 267-282
-
-
Cereghini, S.1
-
9
-
-
0036862511
-
Diabetes mutations delineate an atypical POU domain in HNF-1alpha
-
CHI, Y.I., FRANTZ, J.D., OH, B.C., HANSEN, L., DHE-PAGANON, S., and SHOELSON, S.E. (2002). Diabetes mutations delineate an atypical POU domain in HNF-1alpha. Mol. Cell. 10, 1129-1137.
-
(2002)
Mol. Cell.
, vol.10
, pp. 1129-1137
-
-
Chi, Y.I.1
Frantz, J.D.2
Oh, B.C.3
Hansen, L.4
Dhe-Paganon, S.5
Shoelson, S.E.6
-
10
-
-
0025949412
-
Nuclear targeting sequences - A consensus?
-
DINGWALL, C., and LASKEY, R.A. (1991). Nuclear targeting sequences-A consensus? Trends Biochem. Sci. 16, 478-481.
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 478-481
-
-
Dingwall, C.1
Laskey, R.A.2
-
11
-
-
0024077328
-
The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen
-
DINGWALL, C., ROBBINS, J., DILWORTH, S.M., ROBERTS, B., and RICHARDSON, W.D. (1988). The nucleoplasmin nuclear location sequence is larger and more complex than that of SV-40 large T antigen. J. Cell Biol. 107, 841-849.
-
(1988)
J. Cell Biol.
, vol.107
, pp. 841-849
-
-
Dingwall, C.1
Robbins, J.2
Dilworth, S.M.3
Roberts, B.4
Richardson, W.D.5
-
12
-
-
0024094917
-
The effects of variations in the number and sequence of targeting signals on nuclear uptake
-
DWORETZKY, S.I, LANFORD, R.E., and FELDHERR, C.M. (1988). The effects of variations in the number and sequence of targeting signals on nuclear uptake. J. Cell Biol. 107, 1279-1287.
-
(1988)
J. Cell Biol.
, vol.107
, pp. 1279-1287
-
-
Dworetzky, S.I.1
Lanford, R.E.2
Feldherr, C.M.3
-
13
-
-
0037025334
-
The nucleolar localization domain of the catalytic subunit of human telomerase
-
ETHERIDGE, K.T., BANIK, S.S., ARMBRUSTER, B.N., ZHU, Y., TERNS, R.M., TERNS, M.P., and COUNTER, C.M. (2002). The nucleolar localization domain of the catalytic subunit of human telomerase. J. Biol. Chem. 277, 24764-24770.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24764-24770
-
-
Etheridge, K.T.1
Banik, S.S.2
Armbruster, B.N.3
Zhu, Y.4
Terns, R.M.5
Terns, M.P.6
Counter, C.M.7
-
14
-
-
0035122282
-
Beta-cell genes and diabetes: Molecular and clinical characterization of mutations in transcription factors
-
FRAYLING, T.M., EVANS, J.C., BULMAN, M.P., PEARSON, E., ALLEN, L., OWEN, K., BINGHAM, C., HANNEMANN, M., SHEPHERD, M., ELLARD, S., et al. (2001). Beta-cell genes and diabetes: Molecular and clinical characterization of mutations in transcription factors. Diabetes 50(Suppl 1), S94-100.
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Frayling, T.M.1
Evans, J.C.2
Bulman, M.P.3
Pearson, E.4
Allen, L.5
Owen, K.6
Bingham, C.7
Hannemann, M.8
Shepherd, M.9
Ellard, S.10
-
15
-
-
0025092335
-
Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal
-
HALL, M.N., CRAIK, C., and HIRAOKA, Y. (1990). Homeodomain of yeast repressor alpha 2 contains a nuclear localization signal. Proc. Natl. Acad. Sci. USA 87, 6954-6958.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6954-6958
-
-
Hall, M.N.1
Craik, C.2
Hiraoka, Y.3
-
16
-
-
0033168391
-
The nuclear localization signal (NLS) of PDX-1 is part of the homeodomain and represents a novel type of NLS
-
HESSABI, B., ZIEGLER, P., SCHMIDT, I., HESSABI, C., and WALTHER, R. (1999). The nuclear localization signal (NLS) of PDX-1 is part of the homeodomain and represents a novel type of NLS. Eur. J. Biochem. 263, 170-177.
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 170-177
-
-
Hessabi, B.1
Ziegler, P.2
Schmidt, I.3
Hessabi, C.4
Walther, R.5
-
17
-
-
0030221192
-
Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids
-
MAKKERH, J.P., DINGWALL, C., and LASKEY, R.A. (1996). Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids. Curr Biol. 6, 1025-1027.
-
(1996)
Curr Biol.
, vol.6
, pp. 1025-1027
-
-
Makkerh, J.P.1
Dingwall, C.2
Laskey, R.A.3
-
18
-
-
0030062570
-
The conserved ELK-homeodomain of KNOTTED-I contains two regions that signal nuclear localization
-
MEISEL, L., and LAM, E. (1996). The conserved ELK-homeodomain of KNOTTED-I contains two regions that signal nuclear localization. Plant Mol. Biol. 30, 1-14.
-
(1996)
Plant Mol. Biol.
, vol.30
, pp. 1-14
-
-
Meisel, L.1
Lam, E.2
-
19
-
-
0025281219
-
A myosin-like dimerization helix and an extra-large homeodomain are essential elements of the tripartite DNA binding structure of LFB1
-
NICOSIA, A., MONACI, P., TOMEI, L., DE FRANCESCO, R., NUZZO, M., STUNNENBERG, H., and CORTESE, R. (1990). A myosin-like dimerization helix and an extra-large homeodomain are essential elements of the tripartite DNA binding structure of LFB1. Cell 61, 1225-1236.
-
(1990)
Cell
, vol.61
, pp. 1225-1236
-
-
Nicosia, A.1
Monaci, P.2
Tomei, L.3
De Francesco, R.4
Nuzzo, M.5
Stunnenberg, H.6
Cortese, R.7
-
20
-
-
1842581694
-
Subcellular distribution of ADAR1 isoforms is synergistically determined by three nuclear discrimination signals and a regulatory motif
-
NIE, Y., ZHAO, Q., SU, Y., and YANG, J.H. (2004). Subcellular distribution of ADAR1 isoforms is synergistically determined by three nuclear discrimination signals and a regulatory motif. J. Biol. Chem. 279, 13249-13255.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13249-13255
-
-
Nie, Y.1
Zhao, Q.2
Su, Y.3
Yang, J.H.4
-
21
-
-
0030746904
-
Determination of functional domains of the human transcription factor PAX8 responsible for its nuclear localization and transactivating potential
-
POLEEV, A., OKLADNOVA, O., MUSTI, A.M., SCHNEIDER, S., ROYER-POKORA, B., and PLACHOV, D. (1997). Determination of functional domains of the human transcription factor PAX8 responsible for its nuclear localization and transactivating potential. Eur. J. Biochem. 247, 860-869.
-
(1997)
Eur. J. Biochem.
, vol.247
, pp. 860-869
-
-
Poleev, A.1
Okladnova, O.2
Musti, A.M.3
Schneider, S.4
Royer-Pokora, B.5
Plachov, D.6
-
22
-
-
0035803467
-
Hepatocyte nuclear factor 1alpha controls the expression of terminal complement genes
-
PONTOGLIO, M., PAUSA, M., DOYEN, A., VIOLLET, B., YANIV, M., and TEDESCO, F. (2001). Hepatocyte nuclear factor 1alpha controls the expression of terminal complement genes. J. Exp. Med. 194, 1683-1689.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1683-1689
-
-
Pontoglio, M.1
Pausa, M.2
Doyen, A.3
Viollet, B.4
Yaniv, M.5
Tedesco, F.6
-
23
-
-
0026039369
-
Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1
-
RANEY, A.K., EASTON, A.J., MILICH, D.R., and MCLACHLAN, A. (1991). Promoter-specific transactivation of hepatitis B virus transcription by a glutamine- and proline-rich domain of hepatocyte nuclear factor 1. J. Virol. 65, 5774-5781.
-
(1991)
J. Virol.
, vol.65
, pp. 5774-5781
-
-
Raney, A.K.1
Easton, A.J.2
Milich, D.R.3
McLachlan, A.4
-
24
-
-
0026078249
-
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
-
ROBBINS, J., DILWORTH, S.M., LASKEY, R.A., and DINGWALL, C. (1991). Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623.
-
(1991)
Cell
, vol.64
, pp. 615-623
-
-
Robbins, J.1
Dilworth, S.M.2
Laskey, R.A.3
Dingwall, C.4
-
25
-
-
0034892164
-
Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: Functional and pathological consequences
-
RYFFEL, G.U. (2001). Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: Functional and pathological consequences. J. Mol. Endocrinol. 27, 11-29.
-
(2001)
J. Mol. Endocrinol.
, vol.27
, pp. 11-29
-
-
Ryffel, G.U.1
-
26
-
-
0035512077
-
Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism
-
SHIH, D.Q., SCREENAN, S., MUNOZ, K.N., PHILIPSON, L., PONTOGLIO, M., YANIV, M., POLONSKY, K.S., and STOFFEL, M. (2001). Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes 50, 2472-2480.
-
(2001)
Diabetes
, vol.50
, pp. 2472-2480
-
-
Shih, D.Q.1
Screenan, S.2
Munoz, K.N.3
Philipson, L.4
Pontoglio, M.5
Yaniv, M.6
Polonsky, K.S.7
Stoffel, M.8
-
27
-
-
0030054402
-
Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6
-
SOCK, E., ENDERICH, J., ROSENFELD, M.G., and WEGNER, M. (1996). Identification of the nuclear localization signal of the POU domain protein Tst-1/Oct6. J. Biol. Chem. 271, 17512-17518.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17512-17518
-
-
Sock, E.1
Enderich, J.2
Rosenfeld, M.G.3
Wegner, M.4
-
28
-
-
0027309392
-
The HNF1 C-terminal domain contributes to transcriptional activity and modulates nuclear localisation
-
SOURDIVE, D.J., CHOUARD, T., and YANIV, M. (1993). The HNF1 C-terminal domain contributes to transcriptional activity and modulates nuclear localisation. C R Acad Sci III 316, 385-394.
-
(1993)
C. R. Acad. Sci. III
, vol.316
, pp. 385-394
-
-
Sourdive, D.J.1
Chouard, T.2
Yaniv, M.3
-
29
-
-
12244287057
-
Evidence for haploinsufficiency of the human HNF1 alpha gene revealed by functional characterization of MODY3-associated mutations
-
THOMAS, H., BADENBERG, B., BULMAN, M., LEMM, L, LAUSEN, J., KIND, L., ROOSEN, S., ELLARD, S., HATTERSLEY, A.T. and RYFFEL, G.U. (2002). Evidence for haploinsufficiency of the human HNF1 alpha gene revealed by functional characterization of MODY3-associated mutations. Biol. Chem. 383, 1691-1700.
-
(2002)
Biol. Chem.
, vol.383
, pp. 1691-1700
-
-
Thomas, H.1
Badenberg, B.2
Bulman, M.3
Lemm, L.4
Lausen, J.5
Kind, L.6
Roosen, S.7
Ellard, S.8
Hattersley, A.T.9
Ryffel, G.U.10
-
30
-
-
0025718822
-
Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4
-
TIAN, J.M., and SCHIBLER, U. (1991). Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4. Genes Dev. 5, 2225-2234.
-
(1991)
Genes Dev.
, vol.5
, pp. 2225-2234
-
-
Tian, J.M.1
Schibler, U.2
-
31
-
-
0033531957
-
Loss-of-function and dominant-negative mechanisms associated with hepatocyte nuclear factor-1beta mutations in familial type 2 diabetes mellitus
-
TOMURA, H., NISHIGORI, H., SHO, K., YAMAGATA, K., INOUE, I., and TAKEDA, J. (1999). Loss-of-function and dominant-negative mechanisms associated with hepatocyte nuclear factor-1beta mutations in familial type 2 diabetes mellitus. J. Biol. Chem. 274, 12975-12978.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12975-12978
-
-
Tomura, H.1
Nishigori, H.2
Sho, K.3
Yamagata, K.4
Inoue, I.5
Takeda, J.6
-
32
-
-
0033544962
-
Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations
-
VAXILLAIRE, M., ABDERRAHMANI, A., BOUTIN, P., BAILLEUL, B., FROGUEL, P., YANIV, M., and PONTOGLIO, M. (1999). Anatomy of a homeoprotein revealed by the analysis of human MODY3 mutations. J. Biol. Chem. 274, 35639-35646.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 35639-35646
-
-
Vaxillaire, M.1
Abderrahmani, A.2
Boutin, P.3
Bailleul, B.4
Froguel, P.5
Yaniv, M.6
Pontoglio, M.7
-
33
-
-
4544275385
-
The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformations
-
WU, G., BOHN, S., and RYFFEL, G.U. (2004). The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformations. Eur. J. Biochem. 271, 3715-3728.
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 3715-3728
-
-
Wu, G.1
Bohn, S.2
Ryffel, G.U.3
-
34
-
-
0028012070
-
The transcription factor HNF1 acts with C/EBP alpha to synergistically activate the human albumin promoter through a novel domain
-
WU, K.J., WILSON, D.R., SHIH, C., and DARLINGTON, GJ. (1994). The transcription factor HNF1 acts with C/EBP alpha to synergistically activate the human albumin promoter through a novel domain. J. Biol. Chem. 269, 1177-1182.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1177-1182
-
-
Wu, K.J.1
Wilson, D.R.2
Shih, C.3
Darlington, G.J.4
-
35
-
-
0032766428
-
Nucleolar localization of the UL3 protein of herpes simplex virus type 2
-
YAMADA, H., JIANG, Y.M., ZHU, H.Y., INAGAKI-OHARA, K., and NISHIYAMA, Y. (1999a). Nucleolar localization of the UL3 protein of herpes simplex virus type 2. J. Gen. Virol. 80(Pt 8), 2157-2164.
-
(1999)
J. Gen. Virol.
, vol.80
, Issue.PART 8
, pp. 2157-2164
-
-
Yamada, H.1
Jiang, Y.M.2
Zhu, H.Y.3
Inagaki-Ohara, K.4
Nishiyama, Y.5
-
36
-
-
0033048609
-
Identification of mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with early-onset NIDDM and functional analysis of the mutant proteins
-
YAMADA, S., TOMURA, H., NISHIGORI, H., SHO, K., MABE, H., IWATANI, N., TAKUMI, T., KITO, Y., MORIYA, N., MUROYA, K., et al. (1999b). Identification of mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with early-onset NIDDM and functional analysis of the mutant proteins. Diabetes 48, 645-648.
-
(1999)
Diabetes
, vol.48
, pp. 645-648
-
-
Yamada, S.1
Tomura, H.2
Nishigori, H.3
Sho, K.4
Mabe, H.5
Iwatani, N.6
Takumi, T.7
Kito, Y.8
Moriya, N.9
Muroya, K.10
-
37
-
-
0031848797
-
Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative
-
YAMAGATA, K., YANG, Q., YAMAMOTO, K., IWAHASHI, H., MIYAGAWA, J., OKITA, K., YOSHIUCHI, I., MIYAZAKI, J., NOGUCHI, T., NAKAJIMA, H., et al. (1998). Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative. Diabetes. 47, 1231-1235.
-
(1998)
Diabetes
, vol.47
, pp. 1231-1235
-
-
Yamagata, K.1
Yang, Q.2
Yamamoto, K.3
Iwahashi, H.4
Miyagawa, J.5
Okita, K.6
Yoshiuchi, I.7
Miyazaki, J.8
Noguchi, T.9
Nakajima, H.10
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