Structure of the human type I iodothyronine 5'-deiodinase gene and localization to chromosome 1p32-p33

Genomics

Volumn 42, Issue 2, 1997, Pages 361-363

  Jakobs, Tatjana C ^a   Koehler, Michael R ^a   Schmutzler, Cornelia ^a   Glaser, Florian ^a   Schmid, Michael ^a   Köhrle, Josef ^a,b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Klinische Forschergruppe   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIOTHYRONINE; THYROXINE DEIODINASE;

ANIMAL CELL; ARTICLE; CATALYSIS; CHROMOSOME 1P; CHROMOSOME ANALYSIS; ENZYME ACTIVITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE LOCATION; GENE STRUCTURE; HORMONAL REGULATION; NONHUMAN; PRIORITY JOURNAL; VERTEBRATE;

ANIMALIA; VERTEBRATA;

EID: 0031172520     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.4736     Document Type: Article

References (14)

1. 1. Berry, M. J., Grieco, D., Taylor, B. A., Maia, A. L., Kieffer, J. D., Beamer, W., Glover, E., Poland, A., and Larsen, P. R. (1993). Physiological and genetic analysis of inbred mouse strains with a type 1 iodothyronine 5′ deiodinase defect. J. Clin. Invest. 92: 1517-1528.
2. 2. Blank, R., Eppig, J., Fiedorek, F. T., Frankel, W. N., Friedman, J. M., Huppi, K., Jackson, I., and Mock, B. (1991). Mouse chromosome 4. Mamm. Genome 1: 51-78.
3. 3. Francke, U. (1994). Digitized and differentially shaded human chromosome idiograms for genomic applications. Cytogenet. Cell Genet. 65: 206-219.
4. 4. Jakobs, T. C., Schmutzler, C., and Köhrle, J. (1995). Identification of a T3 responsive element in the upstream regulatory region of the human type 1 5′-deiodinase gene. Thyroid 5: S130(A).
5. 5. Köhler, M. R., and Vogt, P. H. (1994). Interstitial deletions of repetitive DNA blocks in dicentric human Y chromosomes. Chromosoma 103: 324-330.
6. 6. Köhrle, J. (1996). Thyroid hormone deiodinases - A selenoenzyme family acting as gate keepers to thyroid hormone action. Acta Med. Aust. 23: 17-30.
7. 7. Lehrach, H., Drmanac, R., Hoheisel, J., Larin, Z., Lennon, G., Monaco, A. P., Nizetic, D., Zehetner, G., and Poustka, A. (1990) in "Genome Analysis," Vol. 1, "Genetic and Physical Mapping" (K. E. Davies and S. M. Tilghman, Eds.), pp. 39-81, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
8. 8. Maia, A. L., Berry, M. J., Sabbag, R., Harney, J. W., and Larsen, P. R. (1995). Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency. Mol. Endocrinol. 9: 969-980.
9. 9. Mandel, S. J., Berry, M. J., Kieffer, J. D., Harney, J. W., Warne, R. L., and Larsen, P. R. (1992). Cloning and in vitro expression of the human selenoprotein, type 1 iodothyronine deiodinase. J. Clin. Endocrinol. Metab. 75: 1133-1139.
10. 10. Maxon, H. R., Burman, K. D., Premachandra, B. N., Chen, I. W., Burger, A., Levy, P., and Georges, L. P. (1982). Familial elevations of total and free thyroxine in healthy, euthyroid subjects without detectable binding protein abnormalities. Acta Endocrinol. (Copenhagen) 100: 224-230.
11. 11. Pinkel, D., Straume, T., and Gray, J. W. (1986). Cytogenetic analysis using quantitative, high-sensitivity fluorescence hybridization. Proc. Natl. Acad. Sci. USA 83: 2934-2938.
12. 12. Salvatore, D., Bartha, T., Harney, J. W., and Larsen, P. R. (1996). Molecular biology and biochemical characterization of the human type 2 selenodeiodinase. Endocrinology 137: 3308-3315.
13. 13. Schweizer, D. (1976). Reverse fluorescent chromosome banding with chromomycin and DAPI. Chromosoma 58: 307-324.
14. 14. Toyoda, N., Kleinhaus, N., and Larsen, P. R. (1996). The structure of the coding region and 5′-flanking region of the type 1 iodothyronine deiodinase (dio1) gene is normal in a patient with suspected congenital dio1 deficiency. J. Clin. Endocrinol. Metab. 81: 2121-2124.