Up-regulation of mRNA for matrix metalloproteinases-9 and -14 in advanced lesions of demyelinating canine distemper leukoencephalitis

Acta Neuropathologica

Volumn 110, Issue 4, 2005, Pages 369-382

  Gröters, Sibylle ^a   Alldinger, Susanne ^a   Baumgärtner, Wolfgang ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

Canine distemper; Demyelinating diseases; In situ hybridization; Matrix metalloproteinases; Tissue inhibitor of metalloproteinases

Indexed keywords

GELATINASE B; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CANINE DISTEMPER MORBILLIVIRUS; CELL TYPE; CONTROLLED STUDY; DEMYELINATING DISEASE; DOG; DOG DISEASE; ENZYME LOCALIZATION; GENE EXPRESSION; GENE SEQUENCE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHOCYTIC INFILTRATION; MICROGLIA; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGODENDROGLIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RNA SYNTHESIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VIRUS ENCEPHALITIS;

ANIMALS; DISTEMPER; DISTEMPER VIRUS, CANINE; DOGS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IN SITU HYBRIDIZATION; MALE; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 9; RNA, MESSENGER;

EID: 27944511106     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-005-1055-z     Document Type: Article

References (63)

1. Alldinger S, Baumg̈rtner W, Örvell C (1993) Restricted expression of viral surface proteins in canine distemper encephalitis. Acta Neuropathol 85:635-645 10.1007/BF00334674
2. Alldinger S, Wünschmann A, Baumgärtner W, Voss C, Kremmer E (1996) Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis. Acta Neuropathol 92:273-280 10.1007/s004010050518
3. Alldinger S, Fonfara S, Kremmer E, Baumgärtner W (2000) Up-regulation of the hyaluronate receptor CD44 in canine distemper demyelinated plaques. Acta Neuropathol 99:138-146 10672320
4. Annabi B, Thibeault S, Moumdjian R, Beliveau R (2004) Hyaluronan cell surface binding is induced by type I collagen and regulated by caveolae in glioma cells. J Biol Chem 279:21888-21896 10.1074/jbc.M313694200
5. Baker AH, Edwards DR, Murphy G (2002) Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J Cell Sci 115:3719-3727 10.1242/jcs.00063
6. Bar-Or A, Nuttall RK, Duddy M, Alter A, Kim HJ, Ifergan I, Pennington CJ, Bourgin P, Edwards DR, Yong VW (2003) Analyses of all matrix metalloproteinase members in leukocytes emphasize monocytes as major inflammatory mediators in multiple sclerosis. Brain 126:2738-2749 10.1093/brain/awg285
7. Barrett T (1999) Morbillivirus infections, with special emphasis on morbillivirus of carnivores. Vet Microbiol 69:3-13 10.1016/ S0378-1135(99)00080-2
8. Black RA, Rauch CT, Kozlosky CJ, et al (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385:729-733 10.1038/385729a0
9. Brennan FR, O'Neill JK, Allen SJ, Butter C, Nuki G, Baker D (1999) CD44 is involved in selective leucocyte extravasation during inflammatory central nervous system disease. Immunology 98:427-435 10.1046/ j.1365-2567.1999.00894.x
10. Brew K, Dinakarpandian D, Nagase H (2000) Tissue inhibitors of metallo-proteinases: Evolution, structures and function. Biochim Biophys Acta 1477:267-283 10708863
11. Brinckerhoff CE, Matrisian LM (2002) Matrix metalloproteinases: A tail of a frog became a prince. Nat Rev Mol Cell Biol 3:207-214 10.1038/nrm763
12. Chandler S, Coates R, Gearing A, Lury J, Wells G, Bone E (1995) Matrix metalloproteinases degrade myelin basic protein. Neurosci Lett 201:223-226 10.1016/0304-3940(95)12173-0
13. Chandler S, Miller KM, Clements JM, Lury J, Corkill D, Anthony DC, Adams SE, Gearing AJ (1997) Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: An overview. J Neuroimmunol 72:155-161 10.1016/ S0165-5728(96)00179-8
14. Cossins JA, Clements JM, Ford J, Miller KM, Pigott R, Vos W, Walk P van der, Groot CJ de (1997) Enhanced expression of MMP-7 and MMP-9 in demyelinating multiple sclerosis lesions. Acta Neuropathol 94:590-598 10.1007/s004010050754
15. Cuzner ML, Gveric D, Strand C, Loughlin AJ, Paemen L, Opdenakker G, Newcombe J (1996) The expression of tissue-type plasminogen activator, matrix metalloproteases and endogenous inhibitors in the central nervous system in multiple sclerosis: Comparison of stages in lesion evolution. J Neuropathol Exp Neurol 55:1194-1204 8957442
16. Cuzner ML, Opdenakker G (1999) Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system. J Neuroimmunol 94:1-14 10.1016/S0165-5728(98)00241-0
17. Dal Canto MC, Rabinowitz SG (1982) Experimental models of virus-induced demyelination of the central nervous system. Ann Neurol 11:107-109 7059127
18. DeGrendele HC, Estess P, Siegelman MH (1997) Requirement for CD44 in activated T cell extravasation into an inflammatory site. Science 278:672-675 10.1126/science.278.5338.672
19. Frisk AL, Baumgärtner W, Gröne A (1999) Dominating interleukin-10 mRNA expression induction in cerebrospinal fluid cells of dogs with natural canine distemper virus induced demyelinating and non-demyelinating CNS lesions. J Neuroimmunol 97:102-109 10.1016/ S0165-5728(99)00055-7
20. Gaedke K, Zurbriggen A, Baumgärtner W (1997) In vivo and in vitro detection of canine distemper virus nucleoprotein gene with digoxigenin-labelled RNA, double-stranded DNA probes and oligonucleotides by in situ hybridization. Zentralbl Veterinärmed B 44:329-340
21. Gaedke K, Zurbriggen A, Baumgärtner W (1999) Lack of correlation between virus nucleoprotein and mRNA expression and the inflammatory response in demyelinating distemper encephalitis indicates a biphasic disease process. Eur J Vet Pathol 5:9-20
22. Gee K, Kryworuchko M, Kumar A (2004) Recent advances in the regulation of CD44 expression and its role in inflammation and autoimmune diseases. Arch Immunol Ther Exp 52:13-26
23. Gottschall PE, Yu X (1995) Cytokines regulate gelatinase A and B (matrix metalloproteinase 2 and 9) activity in cultured rat astrocytes. J Neurochem 64:1513-1520 7891077
24. Gottschall PE, Deb S (1996) Regulation of matrix metalloproteinase expression in astrocytes, microglia and neurons. Neuroimmunomodulation 3:69-75 8945720
25. Griffin DE (2003) Immune responses to RNA-virus infections of the CNS. Nat Rev Immunol 3:493-502 10.1038/nri1105
26. Gröne A, Fonfara S, Markus S, Baumgärtner W (1999) RT-PCR amplification of various canine cytokines and so-called house-keeping genes in a species-specific macrophage cell line (DH82) and canine peripheral blood leukocytes. J Vet Med B 46:301-310 10.1046/ j.1439-0442.1999.00219.x
27. Gröne A, Alldinger S, Baumgärtner W (2000) Interleukin-1beta, -6, -12 and tumor necrosis factor-alpha expression in brains of dogs with canine distemper virus infection. J Neuroimmunol 110:20-30 10.1016/ S0165-5728(00)00332-5
28. Harkness KA, Adamson P, Sussman JD, Davies-Jones GA, Greenwood J, Woodroofe MN (2000) Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium. Brain 123:698-709 10.1093/brain/ 123.4.698
29. Hartung HP, Kieseier BC (2000) The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system. J Neuroimmunol 107:140-147 10.1016/S0165-5728(00)00225-3
30. Kajita M, Itoh Y, Chiba T, Mori H, Okada A, Kinoh H, Seiki M (2001) Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol 153:893-904 10.1083/jcb.153.5.893
31. Kennedy S, Kuiken T, Jepson PD, Deaville R, Forsyth M, Barrett T, Bildt MW van de, Osterhaus AD, Eybatov T, Duck C, Kydyrmanov A, Mitrofanov I, Wilson S (2000) Mass die-off of Caspian seals caused by canine distemper virus. Emerg Infect Dis 6:637-639 11076723
32. Khuth ST, Akaoka H, Pagenstecher A, Verlaeten O, Belin MF, Giraudon P, Bernard A (2001) Morbillivirus infection of the mouse central nervous system induces region-specific upregulation of MMPs and TIMPs correlated to inflammatory cytokine expression. J Virol 75:8268-8282 10.1128/ JVI.75.17.8268-8282.2001
33. Kieseier BC, Seifert T, Giovannoni G, Hartung HP (1999) Matrix metalloproteinases in inflammatory demyelination: Targets for treatments. Neurology 53:20-25 10.1159/000006579
34. Kouwenhoven M, Özenci V, Gomes A, Yarilin D, Giedraitis V, Press R, Link H (2001) Multiple sclerosis: Elevated expression of matrix metalloproteinases in blood monocytes. J Autoimmun 16:463-470 10.1006/ jaut.2001.0505
35. Leppert D, Lindberg RL, Kappos L, Leib SL (2001) Matrix metalloproteinases: Multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis. Brain Res Brain Res Rev 36:249-257 10.1016/S0165-0173(01)00101-1
36. Lindberg RL, Groot CJ de, Montagne L, Freitag P, Valk P van der, Kappos L, Leppert D (2001) The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis. Brain 124:1743-1753 10.1093/brain/ 124.9.1743
37. Lo EH, Wang X, Cuzner ML (2002) Extracellular proteolysis in brain injury and inflammation: Role for plasminogen activators and matrix metalloproteinases. J Neurosci Res 69:1-9 10.1002/jnr.10270
38. Lukes A, Mun-Bryce S, Lukes M, Rosenberg GA (1999) Extracellular matrix degradation by metalloproteinases and central nervous system disease. Mol Neurobiol 19:267-284 10495107
39. Maeda A, Sobel RA (1996) Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions. J Neuropathol Exp Neurol 55:300-309 8786388
40. Markus S, Failing K, Baumgärtner W (2002) Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions. J Neuroimmunol 125:30-41 10.1016/S0165-5728(02)00027-9
41. Miao C, Baumgärtner W, Failing K, Alldinger S (2003) Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis. Acta Neuropathol 106:486-494 10.1007/s00401-003-0754-6
42. Mun-Bryce S, Rosenberg GA (1998) Gelatinase B modulates selective opening of the blood-brain barrier during inflammation. Am J Physiol 274:R1203-1211 9644031
43. Nagase H, Woessner JF Jr (1999) Matrix metalloproteinases. J Biol Chem 274:21491-21494 10.1074/jbc.274.31.21491
44. Nakagawa T, Kubota T, Kabuto M, Sato K, Kawano H, Hayakawa T, Okada Y (1994) Production of matrix metalloproteinases and tissue inhibitor of metalloproteinase-1 by human brain tumors. J Neurosurg 81:69-77 8207529
45. Oh J, Takahashi R, Kondo S, Mizoguchi A, Adachi E, Sasahara RM, Nishimura S, Imamura Y, Kitayama H, Alexander DB, Ide C, Horan TP, Arakawa T, Yoshida H, Nishikawa S, Itoh Y, Seiki M, Itohara S, Takahashi C, Noda M (2001) The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Cell 107:789-800 10.1016/S0092-8674(01)00597-9
46. Pagenstecher A, Stalder AK, Kincaid CL, Shapiro SD, Campbell IL (1998) Differential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states. Am J Pathol 152:729-741 9502415
47. Pringle CR (2000) Family Paramyxoviridae. In: Regenmortel MHV van, Fauquet CM, Bishop DHL (eds) Virus taxonomy: Classification and nomenclature of viruses. Seventh Report of the International Committee on Taxonomy of Viruses, 1st edn. Academic Press, San Diego, pp 549-561
48. Ries C, Petrides PE (1995) Cytokine regulation of matrix metalloproteinases activity and its regulatory dysfunction in disease. Biol Chem Hoppe Seyler 376:345-355 7576228
49. Rosenberg GA (2002) Matrix metalloproteinases in neuroinflammation. Glia 39:279-291 10.1002/glia.10108
50. Sekine-Aizawa Y, Hama E, Watanabe K, Tsubuki S, Kanai-Azuma M, Kanai Y, Arai H, Aizawa H, Iwata N, Saido TC (2001) Matrix metalloproteinase (MMP) system in brain: Identification and characterization of brain-specific MMP highly expressed in cerebellum. Eur J Neurosci 13:935-948 10.1046/j.0953-816x.2001.01462.x
51. Somerville RP, Oblander SA, Apte SS (2003) Matrix metalloproteinases: old dogs with new tricks. Genome Biol 4:216 10.1186/gb-2003-4-6-216
52. Stamenkovic I (2003) Extracellular matrix remodelling: The role of matrix metalloproteinases. J Pathol 200:448-464 10.1002/path.1400
53. Sternlicht MD, Werb Z (2001) How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17:463-516 10.1146/ annurev.cellbio.17.1.463
54. Strazielle N, Khuth ST, Murat A, Chalon A, Giraudon P, Belin MF, Ghersi-Egea JF (2003) Pro-inflammatory cytokines modulate matrix metalloproteinase secretion and organic anion transport at the blood-cerebrospinal fluid barrier. J Neuropathol Exp Neurol 62:1254-1264 14692701
55. Summers B, Appel MJG (1994) Aspects of canine distemper virus and measles encephalomyelitis. Neuropathol Appl Neurobiol 20:525-534 7898614
56. Visse R, Nagase H (2003) Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry. Circ Res 92:827-839 10.1161/01.RES.0000070112.80711.3D
57. Woessner JF Jr (2002) MMPs and TIMPs - an historical perspective. Mol Biotechnol 22:33-49 10.1385/MB:22:1:033
58. + T cell subsets and B cells in the brain of dogs with spontaneous acute, subacute and chronic-demyelinating distemper encephalitis. J Vet Immunol Immunopathol 67:101-116 10.1016/S0165-2427(98)00216-5
59. Yong VW, Krekoski CA, Forsyth PA, Bell R, Edward DR (1998) Matrix metalloproteinases and diseases of the CNS. Trends Neurosci 21:75-80 10.1016/S0166-2236(97)01169-7
60. Yong VW, Power C, Forsyth P, Edwards DR (2001) Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci 2:502-511 10.1038/35081571
61. Yu Q, Stamenkovic I (1999) Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev 13:35-48 9887098
62. Zurbriggen A, Müller C, Vandevelde M (1993) In situ hybridization of virulent canine distemper virus in brain tissue, using digoxigenin-labeled probes. Am J Vet Res 54:1457-1461 8239133
63. Zurbriggen A, Yamawaki M, Vandevelde M (1993) Restricted canine distemper virus infection of oligodendrocytes. Lab Invest 68:277-284 8450647