-
1
-
-
0035013613
-
Carcinogenesis of malignant lesions of the gallbladder. The impact of chronic inflammation and gallstones
-
Tazuma S and Kajiyama G: Carcinogenesis of malignant lesions of the gallbladder. The impact of chronic inflammation and gallstones. Langenbeck's Arch Surg 386: 224-229, 2001.
-
(2001)
Langenbeck's Arch Surg
, vol.386
, pp. 224-229
-
-
Tazuma, S.1
Kajiyama, G.2
-
2
-
-
0036256948
-
6-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMLH2 is related to poor prognosis in human biliary tract carcinoma
-
6-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMLH2 is related to poor prognosis in human biliary tract carcinoma. Ann Surg Oncol 9: 371-379, 2002.
-
(2002)
Ann Surg Oncol
, vol.9
, pp. 371-379
-
-
Kohya, N.1
Miyazaki, K.2
Matsukura, S.3
Yakushiji, Y.4
Kitajima, Y.5
Kitahara, K.6
Fukuhara, M.7
Nakabeppu, Y.8
Sekiguchi, M.9
-
3
-
-
0021740289
-
Covalent modification of DNA by antineoplastic agents
-
Hemminki K and Ludlum DB: Covalent modification of DNA by antineoplastic agents. J Natl Cancer Inst 73: 1021-1028, 1984.
-
(1984)
J Natl Cancer Inst
, vol.73
, pp. 1021-1028
-
-
Hemminki, K.1
Ludlum, D.B.2
-
4
-
-
0028690472
-
DNA adducts of N-nitrosoureas
-
Hemminki K et al. (eds.). IARC Scientific Publications no. 125. IARC, Lyon
-
Eisenbrand G, Pfeiffer C and Tang W: DNA adducts of N-nitrosoureas. In: DNA Adducts: Identification and Biological Significance, Hemminki K et al. (eds.). IARC Scientific Publications no. 125. IARC, Lyon, pp. 277-293, 1994.
-
(1994)
DNA Adducts: Identification and Biological Significance
, pp. 277-293
-
-
Eisenbrand, G.1
Pfeiffer, C.2
Tang, W.3
-
5
-
-
0028709432
-
DNA adducts of nitrogen mustards and ethylene imines
-
Hemminki K et al. (eds.). IARC Scientific Publications no. 125. IARC, Lyon
-
Hemminki K: DNA adducts of nitrogen mustards and ethylene imines. In: DNA Adducts: Identification and Biological Significance, Hemminki K et al. (eds.). IARC Scientific Publications no. 125. IARC, Lyon, pp. 313-321, 1994.
-
(1994)
DNA Adducts: Identification and Biological Significance
, pp. 313-321
-
-
Hemminki, K.1
-
6
-
-
0028694685
-
DNA alkylation by triazenes and related compounds
-
Hemminki K et al. (eds.). IARC Scientific Publications no. 125. IARC, Lyon
-
Michejda CJ, Smith RH Jr and Kroeger-Koepke MB: DNA alkylation by triazenes and related compounds. In: DNA Adducts: Identification and Biological Significance, Hemminki K et al. (eds.). IARC Scientific Publications no. 125. IARC, Lyon, pp. 323-337, 1994.
-
(1994)
DNA Adducts: Identification and Biological Significance
, pp. 323-337
-
-
Michejda, C.J.1
Smith Jr., R.H.2
Kroeger-Koepke, M.B.3
-
7
-
-
1942469956
-
MGMT: Its role in cancer aetiology and cancer therapeutics
-
Gerson SL: MGMT: Its role in cancer aetiology and cancer therapeutics. Nature Rev Cancer 4: 296-307, 2004.
-
(2004)
Nature Rev Cancer
, vol.4
, pp. 296-307
-
-
Gerson, S.L.1
-
8
-
-
0023919219
-
Regulation and expression of the adaptive response to alkylating agents
-
Lindahl T, Sedgwick B, Sekiguchi M and Nakabuppu Y: Regulation and expression of the adaptive response to alkylating agents. Annu Rev Biochem 57: 133-157, 1998.
-
(1998)
Annu Rev Biochem
, vol.57
, pp. 133-157
-
-
Lindahl, T.1
Sedgwick, B.2
Sekiguchi, M.3
Nakabuppu, Y.4
-
9
-
-
0019211791
-
6-methylguanine to a protein cysteine residue
-
6-methylguanine to a protein cysteine residue. J Biol Chem 255: 10569-10571, 1980.
-
(1980)
J Biol Chem
, vol.255
, pp. 10569-10571
-
-
Olsson, M.1
Lindahl, T.2
-
10
-
-
0002048709
-
Adaptive response: Induced synthesis of DNA repair enzymes by alkylating agents
-
Sekiguchi M and Nakabeppu Y: Adaptive response: induced synthesis of DNA repair enzymes by alkylating agents. Trends Genet 3: 51-54, 1987.
-
(1987)
Trends Genet
, vol.3
, pp. 51-54
-
-
Sekiguchi, M.1
Nakabeppu, Y.2
-
12
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V, Baylin SB and Herman JG: Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. New Engl J Med 343: 1350-1354, 2000.
-
(2000)
New Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
Baylin, S.B.7
Herman, J.G.8
-
13
-
-
0025195404
-
6-alkylguanine-DNA alkyltransferase: Regulation and importance in response to alkylating carcinogenic and therapeutic agents
-
6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 50: 6119-6129, 1990.
-
(1990)
Cancer Res
, vol.50
, pp. 6119-6129
-
-
Pegg, A.E.1
-
14
-
-
0036570062
-
Clinical relevance of MGMT in the treatment of cancer
-
Gerson SL: Clinical relevance of MGMT in the treatment of cancer. J Clin Oncol 20: 2388-2399, 2002.
-
(2002)
J Clin Oncol
, vol.20
, pp. 2388-2399
-
-
Gerson, S.L.1
-
15
-
-
0031906084
-
The role of DNA mismatch repair in drug resistance
-
Fink D, Aebi S and Howell SB: The role of DNA mismatch repair in drug resistance. Clin Cancer Res 4: 1-6, 1998.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1-6
-
-
Fink, D.1
Aebi, S.2
Howell, S.B.3
-
16
-
-
0031848832
-
Involvement of the mismatch repair system in temozolomide-induced apoptosis
-
D'atri S, Tentori L, Lacal PM, Graziani G, Pagani E, Benincasa E, Zambruno G, Bonimassar E and Jiricny J: Involvement of the mismatch repair system in temozolomide-induced apoptosis. Mol Pharmacol 54: 334-341, 1998.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 334-341
-
-
D'Atri, S.1
Tentori, L.2
Lacal, P.M.3
Graziani, G.4
Pagani, E.5
Benincasa, E.6
Zambruno, G.7
Bonimassar, E.8
Jiricny, J.9
-
17
-
-
0027292234
-
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
-
Kat A, Thilly WG, Fang WH, Longley MJ, Li GM and Modrich P: An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc Natl Acad Sci USA 90: 6424-6428, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6424-6428
-
-
Kat, A.1
Thilly, W.G.2
Fang, W.H.3
Longley, M.J.4
Li, G.M.5
Modrich, P.6
-
18
-
-
0030479125
-
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-Bis(2-chloroethyl)nitrosourea
-
Liu L, Markowitz S and Gerson SL: Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-Bis(2-chloroethyl)nitrosourea. Cancer Res 56: 5375-5379, 1996.
-
(1996)
Cancer Res
, vol.56
, pp. 5375-5379
-
-
Liu, L.1
Markowitz, S.2
Gerson, S.L.3
-
19
-
-
0002265020
-
Protocols for screening chemical agents and natural products against animal tumors and other biological systems
-
Geran RI, Greenberg NH, Macdonald MM, Schumacher AM and Abbort BJ: Protocols for screening chemical agents and natural products against animal tumors and other biological systems. Cancer Chemother Rep 3: 51-61, 1972.
-
(1972)
Cancer Chemother Rep
, vol.3
, pp. 51-61
-
-
Geran, R.I.1
Greenberg, N.H.2
Macdonald, M.M.3
Schumacher, A.M.4
Abbort, B.J.5
-
21
-
-
0033807872
-
Chemotherapy for gallbladder carcinoma - A surgeon's perspective
-
Todoroki T: Chemotherapy for gallbladder carcinoma - a surgeon's perspective. Hepato-gastroenterology 47: 948-955, 2000.
-
(2000)
Hepato-Gastroenterology
, vol.47
, pp. 948-955
-
-
Todoroki, T.1
-
22
-
-
0001471904
-
Chemotherapy for unresectable biliary cancer
-
Takada T and Uchiyama K: Chemotherapy for unresectable biliary cancer. Kan Tan Sui (In Japanese) 25: 695-699, 1992.
-
(1992)
Kan Tan Sui (In Japanese)
, vol.25
, pp. 695-699
-
-
Takada, T.1
Uchiyama, K.2
-
23
-
-
0027182199
-
Phase II trial of mitomycin(MMC) in advanced gallbladder and biliary tree carcinoma. An EORTC gastrointestinal tract cancer cooperative group study
-
Taal BG, Audisio RA, Bleiberg H, Blijham GH, Neijt JP, Veenhof CH Duez N and Sahmoud T: Phase II trial of mitomycin(MMC) in advanced gallbladder and biliary tree carcinoma. An EORTC gastrointestinal tract cancer cooperative group study. Ann Oncol 4: 607-609, 1993.
-
(1993)
Ann Oncol
, vol.4
, pp. 607-609
-
-
Taal, B.G.1
Audisio, R.A.2
Bleiberg, H.3
Blijham, G.H.4
Neijt, J.P.5
Veenhof, C.H.6
Duez, N.7
Sahmoud, T.8
-
24
-
-
0028053595
-
A phase II study of cisplatin in patients with biliary tract carcinoma
-
Okada S, Ishii H, Nose H, Yoshimori M, Okusaka T, Aoki K, Iwasaki M, Furuse J and Yoshino M: A phase II study of cisplatin in patients with biliary tract carcinoma. Oncology 57: 515-517, 1994.
-
(1994)
Oncology
, vol.57
, pp. 515-517
-
-
Okada, S.1
Ishii, H.2
Nose, H.3
Yoshimori, M.4
Okusaka, T.5
Aoki, K.6
Iwasaki, M.7
Furuse, J.8
Yoshino, M.9
-
25
-
-
0032526183
-
A phase II study of 5-fluorouracil, leucovorin, and carboplatin in patients with unresectable biliary tree carcinoma
-
Sanz-Altamira PM, Ferrante K, Jenkins RL, Lewis WD, Huberman MS and Stuart KE: A phase II study of 5-fluorouracil, leucovorin, and carboplatin in patients with unresectable biliary tree carcinoma. Cancer 82: 2321-2325, 1998.
-
(1998)
Cancer
, vol.82
, pp. 2321-2325
-
-
Sanz-Altamira, P.M.1
Ferrante, K.2
Jenkins, R.L.3
Lewis, W.D.4
Huberman, M.S.5
Stuart, K.E.6
-
26
-
-
0032574814
-
Separation killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
-
Kawate H, Sakumi K, Tsuzuki T, Nakatsuru Y, Ishikawa T, Takahashi S, Takano H, Noda T and Sekiguchi M: Separation killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc Natl Acad Sci 95: 5116-5120, 1998.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 5116-5120
-
-
Kawate, H.1
Sakumi, K.2
Tsuzuki, T.3
Nakatsuru, Y.4
Ishikawa, T.5
Takahashi, S.6
Takano, H.7
Noda, T.8
Sekiguchi, M.9
-
27
-
-
27944441868
-
Phase I and preliminary phase II study of 1-(4-amino-2-methyl-5- pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) administered by intermittent dose schedule
-
Saito T, Yokoyama M, Himori T, Ujiie S, Sugawara N, Sugiyama Z and Kitada K: Phase I and preliminary phase II study of 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU) administered by intermittent dose schedule. Jpn J Cancer Chemother 4: 991-1004, 1977.
-
(1977)
Jpn J Cancer Chemother
, vol.4
, pp. 991-1004
-
-
Saito, T.1
Yokoyama, M.2
Himori, T.3
Ujiie, S.4
Sugawara, N.5
Sugiyama, Z.6
Kitada, K.7
-
29
-
-
0036252540
-
DNA mismatch repair defects: Role in colorectal carcinogenesis
-
Jacob S and Praz F: DNA mismatch repair defects: role in colorectal carcinogenesis. Biochimie 84: 27-47, 2002.
-
(2002)
Biochimie
, vol.84
, pp. 27-47
-
-
Jacob, S.1
Praz, F.2
-
30
-
-
0032851842
-
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
-
Hickman MJ and Samson LD: Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc Natl Acad Sci USA 96: 10764-10769, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10764-10769
-
-
Hickman, M.J.1
Samson, L.D.2
-
31
-
-
0033513097
-
Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis
-
Wu J, Gu L Wang H, Geacintov NE and Li GM: Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis. Mol Cell Biol 19: 8292-8301, 1999.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8292-8301
-
-
Wu, J.1
Gu, L.2
Wang, H.3
Geacintov, N.E.4
Li, G.M.5
-
32
-
-
0023159821
-
6-alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing, 1,3-bis(2-chloro-ethyl)-1-nitrosourea - Induced precursors of interstrand cross-links
-
6- alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing, 1,3-bis(2-chloro-ethyl)-1-nitrosourea - induced precursors of interstrand cross-links. Biochem Biophys Res Commun 142: 341-347, 1987.
-
(1987)
Biochem Biophys Res Commun
, vol.142
, pp. 341-347
-
-
Brent, T.P.1
Smith, D.G.2
Remack, J.S.3
-
33
-
-
0026602568
-
Formation and disappearance of DNA interstrand cross-links in human colon tumor cell lines with different levels of resistance to chlorozotocin
-
Srivenugopal KD: Formation and disappearance of DNA interstrand cross-links in human colon tumor cell lines with different levels of resistance to chlorozotocin. Biochem Phrmacol 433: 1159-1163, 1992.
-
(1992)
Biochem Phrmacol
, vol.433
, pp. 1159-1163
-
-
Srivenugopal, K.D.1
-
34
-
-
0024478011
-
6-alkylguanine-DNA alkyltransferase in limiting nitrosourea induced sister chromatid exchanges in proliferating human lymphocytes
-
6-alkylguanine-DNA alkyltransferase in limiting nitrosourea induced sister chromatid exchanges in proliferating human lymphocytes. Cancer Res 49: 1899-1903, 1989.
-
(1989)
Cancer Res
, vol.49
, pp. 1899-1903
-
-
Trey, J.E.1
Gerson, S.L.2
|