Leptostatin: A synthetic hybrid of the cytotoxic polyketides callystatin A and leptomycin B

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 2, 2006, Pages 320-323

  Marshall, James A ^a   Mikowski, Ann M ^a   Bourbeau, Matthew P ^a   Schaaf, Gregory M ^a   Valeriote, Frederick ^b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b Josephine Ford Cancer Center   (United States)

Author keywords

Chiral allenylstannane; Colon cancer; Cytotoxic compounds; Diastereoselective additions; Lactone; Polyketide

Indexed keywords

ARTICLE; SYNTHESIS;

CELL LINE, TUMOR; CELL SURVIVAL; DRUG EVALUATION, PRECLINICAL; FATTY ACIDS, UNSATURATED; HUMANS; MOLECULAR CONFORMATION; STEREOISOMERISM;

EID: 27944453856     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.084     Document Type: Article

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