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Volumn 286, Issue 2, 2003, Pages 321-331

Ratjadones inhibit nuclear export by blocking CRM1/exportin 1

Author keywords

CRM1; Exportin 1; Leptomycin B; Nuclear export; Ratjadone

Indexed keywords

POLYKETIDE; RATJADONE A; RATJADONE B; RATJADONE C; RATJADONE D; UNCLASSIFIED DRUG;

EID: 18544412268     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00100-9     Document Type: Article
Times cited : (78)

References (45)
  • 1
    • 0033178866 scopus 로고    scopus 로고
    • Getting across the nuclear pore complex
    • Talcott B., Moore M.S. Getting across the nuclear pore complex. Trends Cell Biol. 9:1999;312-318.
    • (1999) Trends Cell Biol. , vol.9 , pp. 312-318
    • Talcott, B.1    Moore, M.S.2
  • 2
    • 0035831045 scopus 로고    scopus 로고
    • Protein mobility within the nucleus - What are the right moves?
    • Pederson T. Protein mobility within the nucleus - what are the right moves? Cell. 104:2001;635-638.
    • (2001) Cell , vol.104 , pp. 635-638
    • Pederson, T.1
  • 3
    • 0031707505 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: The soluble phase
    • Mattaj I.W., Englmeier L. Nucleocytoplasmic transport the soluble phase . Annu. Rev. Biochem. 67:1998;265-306.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 265-306
    • Mattaj, I.W.1    Englmeier, L.2
  • 4
    • 85047673784 scopus 로고    scopus 로고
    • Regulation of transcription factor localization: Fine-tuning of gene expression
    • Vandromme M., Gauthier-Rouviere C., Lamb N., Fernandez A. Regulation of transcription factor localization fine-tuning of gene expression . TIBS. 21:1996;59-64.
    • (1996) TIBS , vol.21 , pp. 59-64
    • Vandromme, M.1    Gauthier-Rouviere, C.2    Lamb, N.3    Fernandez, A.4
  • 7
    • 0039115156 scopus 로고    scopus 로고
    • Transport into and out of the cell nucleus
    • Görlich D. Transport into and out of the cell nucleus. EMBO J. 17:1998;2721-2727.
    • (1998) EMBO J. , vol.17 , pp. 2721-2727
    • Görlich, D.1
  • 8
    • 0032078933 scopus 로고    scopus 로고
    • Importins and exportins: How to get in and out of the nucleus
    • Weis K. Importins and exportins how to get in and out of the nucleus . TIBS. 23:1998;185-189.
    • (1998) TIBS , vol.23 , pp. 185-189
    • Weis, K.1
  • 9
    • 0024654957 scopus 로고
    • + which encodes a 115-kD protein preferentially localized in the nucleus and at its periphery
    • + which encodes a 115-kD protein preferentially localized in the nucleus and at its periphery. J. Cell Biol. 108:1989;1195-1207.
    • (1989) J. Cell Biol. , vol.108 , pp. 1195-1207
    • Adachi, Y.1    Yanagida, M.2
  • 10
    • 0034913423 scopus 로고    scopus 로고
    • Importin-beta-like nuclear transport receptors
    • reviews
    • Ström A.C., Weis K. Importin-beta-like nuclear transport receptors. Genome Biol. 2:2001;3008.1-3008.9. reviews.
    • (2001) Genome Biol. , vol.2 , pp. 30081-30089
    • Ström, A.C.1    Weis, K.2
  • 11
    • 0026419320 scopus 로고
    • Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
    • Bischoff F.R., Ponstingl H. Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature. 354:1991;80-82.
    • (1991) Nature , vol.354 , pp. 80-82
    • Bischoff, F.R.1    Ponstingl, H.2
  • 13
    • 0033577860 scopus 로고    scopus 로고
    • A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export
    • Kehlenbach R.H., Dickmanns A., Kehlenbach A., Guan T., Gerace L. A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. J. Cell Biol. 145:1999;645-657.
    • (1999) J. Cell Biol. , vol.145 , pp. 645-657
    • Kehlenbach, R.H.1    Dickmanns, A.2    Kehlenbach, A.3    Guan, T.4    Gerace, L.5
  • 15
    • 0028843898 scopus 로고
    • Ratjadon: A new antifungal compound from Sorangium cellulosum (Myxobacteria) - Production, physico-chemical and biological properties
    • Gerth K., Schummer D., Höfle G., Irschik H., Reichenbach H. Ratjadon a new antifungal compound from Sorangium cellulosum (Myxobacteria) - production, physico-chemical and biological properties . J. Antibiotics. 48:1995;973-976.
    • (1995) J. Antibiotics , vol.48 , pp. 973-976
    • Gerth, K.1    Schummer, D.2    Höfle, G.3    Irschik, H.4    Reichenbach, H.5
  • 19
    • 0020606355 scopus 로고
    • Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization
    • Hamamoto T., Gunji S., Tjuji H., Beppu T. Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization. J. Antibiot. 36:1983;639-645.
    • (1983) J. Antibiot. , vol.36 , pp. 639-645
    • Hamamoto, T.1    Gunji, S.2    Tjuji, H.3    Beppu, T.4
  • 20
    • 0020571348 scopus 로고
    • Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation
    • Hamamoto T., Seto H., Beppu T. Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation. J. Antibiot. 36:1983;646-650.
    • (1983) J. Antibiot. , vol.36 , pp. 646-650
    • Hamamoto, T.1    Seto, H.2    Beppu, T.3
  • 21
    • 0030924190 scopus 로고    scopus 로고
    • CRM1 is an export receptor for leucine-rich export signals
    • Fornerod M., Ohno M., Yoshida M., Mattaj I.W. CRM1 is an export receptor for leucine-rich export signals. Cell. 90:1997;1051-1060.
    • (1997) Cell , vol.90 , pp. 1051-1060
    • Fornerod, M.1    Ohno, M.2    Yoshida, M.3    Mattaj, I.W.4
  • 22
    • 0030831534 scopus 로고    scopus 로고
    • CRM1 is responsible for intracellular transport mediated by the nuclear export signal
    • Fukuda M., Asano S., Nakamura T., Adachi M., Yoshida M., Yanygrida M., Nishida E. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature. 390:1997;308-311.
    • (1997) Nature , vol.390 , pp. 308-311
    • Fukuda, M.1    Asano, S.2    Nakamura, T.3    Adachi, M.4    Yoshida, M.5    Yanygrida, M.6    Nishida, E.7
  • 23
    • 0030748907 scopus 로고    scopus 로고
    • Evidence for a role of CRM1 in signal-mediated nuclear protein export
    • Ossareh-Nazari B., Bachelerie F., Dargemont C. Evidence for a role of CRM1 in signal-mediated nuclear protein export. Science. 278:1997;141-144.
    • (1997) Science , vol.278 , pp. 141-144
    • Ossareh-Nazari, B.1    Bachelerie, F.2    Dargemont, C.3
  • 24
    • 0031079648 scopus 로고    scopus 로고
    • LMB is an inhibitor of nuclear export: Inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA
    • Wolff B., Sanglier J.-J., Wang Y. LMB is an inhibitor of nuclear export inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA . Chem. Biol. 4:1997;139-147.
    • (1997) Chem. Biol. , vol.4 , pp. 139-147
    • Wolff, B.1    Sanglier, J.-J.2    Wang, Y.3
  • 27
    • 0033168194 scopus 로고    scopus 로고
    • The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae
    • Neville M., Rosbash M. The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae. EMBO J. 18:1999;3747-3756.
    • (1999) EMBO J. , vol.18 , pp. 3747-3756
    • Neville, M.1    Rosbash, M.2
  • 28
    • 0028318159 scopus 로고
    • LMB targets a regulatory cascade of CRM1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
    • Nishi K., Yoshida M., Fujiwara D., Nishikawa M., Horinouchi S., Beppu T. LMB targets a regulatory cascade of CRM1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J. Biol. Chem. 269:1994;6320-6324.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6320-6324
    • Nishi, K.1    Yoshida, M.2    Fujiwara, D.3    Nishikawa, M.4    Horinouchi, S.5    Beppu, T.6
  • 29
    • 0028043504 scopus 로고
    • A multifuctional vector family for gene expression in mammalian cells
    • Dirks W., Schaper F., Kirchhoff S., Morelle C., Hauser H. A multifuctional vector family for gene expression in mammalian cells. Gene. 149:1994;387-388.
    • (1994) Gene , vol.149 , pp. 387-388
    • Dirks, W.1    Schaper, F.2    Kirchhoff, S.3    Morelle, C.4    Hauser, H.5
  • 30
    • 0033558170 scopus 로고    scopus 로고
    • Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins
    • Köster M., Hauser H. Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins. Eur. J. Biochem. 260:1999;137-144.
    • (1999) Eur. J. Biochem. , vol.260 , pp. 137-144
    • Köster, M.1    Hauser, H.2
  • 31
    • 0035847054 scopus 로고    scopus 로고
    • A role for the basic patch and the C terminus of RanGTP in regulating the dynamic interactions with importin beta, CRM1 and RanBP1
    • Nilsson J., Askjaer P., Kjems J. A role for the basic patch and the C terminus of RanGTP in regulating the dynamic interactions with importin beta, CRM1 and RanBP1. J. Mol. Biol. 305:2001;231-243.
    • (2001) J. Mol. Biol. , vol.305 , pp. 231-243
    • Nilsson, J.1    Askjaer, P.2    Kjems, J.3
  • 32
    • 0029972194 scopus 로고    scopus 로고
    • The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
    • Haspel R.L., Salditt-Georgieff M., Darnell J.E. Jr. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J. 15:1996;6262-6268.
    • (1996) EMBO J. , vol.15 , pp. 6262-6268
    • Haspel, R.L.1    Salditt-Georgieff, M.2    Darnell J.E., Jr.3
  • 33
    • 0034779253 scopus 로고    scopus 로고
    • CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain
    • Poulsen H., Nilsson J., Damgaard C.K., Egebjerg J., Kjems J. CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain. Mol. Cell. Biol. 21:2001;7862-7871.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 7862-7871
    • Poulsen, H.1    Nilsson, J.2    Damgaard, C.K.3    Egebjerg, J.4    Kjems, J.5
  • 34
    • 0038554478 scopus 로고    scopus 로고
    • New derivatives of pyrroline N-oxides as spin traps
    • Arya P. New derivatives of pyrroline N-oxides as spin traps. Heterocycles. 43:(2):1996;397-407.
    • (1996) Heterocycles , vol.43 , Issue.2 , pp. 397-407
    • Arya, P.1
  • 35
    • 0015416821 scopus 로고
    • High interferon producing line of transformed murine cells
    • Oie H.K., Gazdar A.F., Buckler C.E., Baron S. High interferon producing line of transformed murine cells. J. Gen. Virol. 17:1977;107-109.
    • (1977) J. Gen. Virol. , vol.17 , pp. 107-109
    • Oie, H.K.1    Gazdar, A.F.2    Buckler, C.E.3    Baron, S.4
  • 36
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham F.L., van der Eb A.J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:1973;456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van der Eb, A.J.2
  • 37
    • 0023945548 scopus 로고
    • Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker
    • de la Luna S., Soria I., Pulido D., Ortin J., Jiménez A. Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker. Gene. 62:1988;121-126.
    • (1988) Gene , vol.62 , pp. 121-126
    • De la Luna, S.1    Soria, I.2    Pulido, D.3    Ortin, J.4    Jiménez, A.5
  • 38
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxic assays
    • Moosmann T. Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxic assays . J. Immunol. Methods. 65:1983;55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Moosmann, T.1
  • 39
    • 0032509524 scopus 로고    scopus 로고
    • The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP
    • Askjaer P., Jensen T.H., Nilsson J., Englmeier L., Kjems J. The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP. J. Biol. Chem. 273:1998;33414-33422.
    • (1998) J. Biol. Chem. , vol.273 , pp. 33414-33422
    • Askjaer, P.1    Jensen, T.H.2    Nilsson, J.3    Englmeier, L.4    Kjems, J.5
  • 40
    • 0029130169 scopus 로고
    • The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
    • Fischer U., Huber J., Boelens W.C., Mattaj I.W., Lührmann R. The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell. 82:1995;475-483.
    • (1995) Cell , vol.82 , pp. 475-483
    • Fischer, U.1    Huber, J.2    Boelens, W.C.3    Mattaj, I.W.4    Lührmann, R.5
  • 41
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell J.E. Jr. STATs and gene regulation. Science. 277:1997;1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell J.E., Jr.1
  • 42
    • 0034887171 scopus 로고    scopus 로고
    • Polyketide biosynthesis: A millenium review
    • Staunton J., Weissmann K.J. Polyketide biosynthesis a millenium review . Natural Product Rep. 18:2001;380-416.
    • (2001) Natural Product Rep , vol.18 , pp. 380-416
    • Staunton, J.1    Weissmann, K.J.2
  • 43
    • 0035122485 scopus 로고    scopus 로고
    • Induction of apoptosis in chronic myelogenous leukemic cells through nuclear entrapment of BCR-ABL tyrosine kinase
    • Vigneri P., Wang J.Y.J. Induction of apoptosis in chronic myelogenous leukemic cells through nuclear entrapment of BCR-ABL tyrosine kinase. Nature Med. 7:2001;228-234.
    • (2001) Nature Med. , vol.7 , pp. 228-234
    • Vigneri, P.1    Wang, J.Y.J.2
  • 44
    • 0030856315 scopus 로고    scopus 로고
    • The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus
    • Izaurralde E., Kutay U., von Kobbe C., Mattaj I.W., Gorlich D. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 16:1997;6535-6547.
    • (1997) EMBO J. , vol.16 , pp. 6535-6547
    • Izaurralde, E.1    Kutay, U.2    Von Kobbe, C.3    Mattaj, I.W.4    Gorlich, D.5
  • 45
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H., Steahelin T., Gordon F. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets procedure and some applications . Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Steahelin, T.2    Gordon, F.3


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