Total synthesis of callystatin A, a potent cytotoxic polyketide from the marine sponge, Callyspongia truncata

Tetrahedron Letters

Volumn 39, Issue 16, 1998, Pages 2349-2352

  Murakami, Nobutoshi ^a   Wang, Weiqi ^a   Aoki, Masashi ^a   Tsutsui, Yasuhiro ^a   Sugimoto, Masanori ^a   Kobayashi, Motomasa ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALLYSTATIN A; CYTOTOXIC AGENT; POLYKETIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ISOLATION; DRUG SYNTHESIS; POLYMERIZATION; SPONGE (PORIFERA); STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 0032537206     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00151-8     Document Type: Article

References (10)

1. 1. Kobayashi, M.; Higuchi, K.; Murakami, N.; Tajima, H.; Aoki, S. Tetrahedron Lett., 1997, 38, 2859-2862.
2. 2. Murakami, N.; Wang, W.; Aoki, M.; Tsutsui, Y.; Higuchi, K.; Aoki, S.; Kobayashi, M. Tetrahedron Lett., 1997, 38, 5533-5536.
3. 3. Tamura, R.; Saegusa, K.; Kakihana M.; Oda, D. J. Org. Chem., 1988, 53, 2723-2728.
4. 4. Evans, D. A.; Bartroli, J.; Shih, T. L. J. Am. Chem. Soc., 1981, 103, 2127-2129.
5. 5. Tsubuki, M.; Kanai, K.; Honda, T. Heterocycles, 1993, 35, 281-288.
6. 6. Boger, D. L.; Hikota, M.; Lewis, B. M. J. Org. Chem., 1997, 62, 1748-1753.
7. 7. Carretero, J. C.; Ghosez, L. Tetrahedron Lett., 1988, 29, 2059-2062.
8. 8. Numbering of each intermediate is in accordance with that of callystatin A (1) to avoid confusion.
9. 9. a) Basha, A.; Lipton, M.; Weinreb, S. M. Tetrahedron Lett., 1977, 4171-4174;
10. b) Evans, D. A.; Bender, S. L.; Morris, J. J. Am. Chem. Soc., 1988, 110, 2506-2526.