메뉴 건너뛰기




Volumn 86, Issue 11, 2001, Pages 1124-1157

Myelodysplastic syndromes: Recent advances

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AMIFOSTINE; BENZENE DERIVATIVE; CALICHEAMICIN; CYCLOSPORIN A; CYTARABINE; DAUNORUBICIN; DOXORUBICIN; EPIPODOPHYLLOTOXIN; ETOPOSIDE; FLUDARABINE; GEMTUZUMAB OZOGAMICIN; GENE PRODUCT; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IDARUBICIN; INTERLEUKIN 3; MELPHALAN; ORGANIC SOLVENT; PROTEIN NF1; RAS PROTEIN; RECOMBINANT ERYTHROPOIETIN; THYMOCYTE ANTIBODY; TIOGUANINE; TOPOTECAN; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

EID: 0035164689     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (34)

References (260)
  • 2
    • 0033967640 scopus 로고    scopus 로고
    • A hypothesis for the pathogenesis of myelodysplastic syndromes: Implications for new therapies
    • (2000) Leukemia , vol.14 , pp. 2-8
    • Rosenfeld, C.1    List, A.2
  • 13
    • 0034243037 scopus 로고    scopus 로고
    • Alternative to conventional or myeloablative chemotherapy in myelodysplastic syndrome
    • (2000) Int J Hematol , vol.72 , pp. 134-138
    • Cazzola, M.1
  • 16
    • 0003345327 scopus 로고    scopus 로고
    • Depletion of lymphocytes increases the in vitro hemopoiesis in long-term bone marrow cultures (LTBMC) from patients with myelodysplastic syndrome (MDS): Implications for the immunosuppressive therapy
    • (1999) Blood , vol.94
    • Scheid, C.1    Baumann, I.2    Santibanef Koref, F.3
  • 19
    • 0032171391 scopus 로고    scopus 로고
    • Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: Relation to disease progression
    • (1998) Leuk Res , vol.22 , pp. 767-777
    • Davis, R.E.1    Greenberg, P.L.2
  • 26
    • 0031464758 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor (TNF)-α and interferon (IFN)-γ by bone marrow cells from patients with myelodysplastic syndromes
    • (1997) Leukemia , vol.11 , pp. 2049-2054
    • Kitagawa, M.1    Saito, I.2    Kuwata, T.3
  • 36
  • 39
    • 0032784783 scopus 로고    scopus 로고
    • World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: Report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997
    • (1999) J Clin Oncol , vol.17 , pp. 3835-3849
    • Harris, N.L.1    Jaffe, E.S.2    Diebold, J.3
  • 46
    • 0024402407 scopus 로고
    • Two regression models and a scoring system for predicting survival and planning treatment in myelodysplastic syndromes: A multivariate analysis of prognostic factors in 370 patients
    • (1989) Blood , vol.74 , pp. 395-408
    • Sanz, G.F.1    Sanz, M.A.2    Vallespi, T.3
  • 48
    • 0027372507 scopus 로고
    • Cytogenetic analysis has strong independent prognostic value in de novo myelodysplastic syndromes and can be incorporated in a new scoring system: A report on 408 cases
    • (1993) Leukemia , vol.7 , pp. 1315-1323
    • Morel, P.1    Hebbar, M.2    Lai, J.L.3
  • 49
  • 56
    • 0021854535 scopus 로고
    • Prognostic factors in the myelodysplastic syndromes: Importance of initial data on peripheral blood counts, bone marrow cytology, trephine biopsy and chromosomal analysis
    • (1985) Br J Haematol , vol.60 , pp. 19-32
    • Tricot, G.1    Vlietinck, R.2    Boogaerts, M.A.3
  • 63
    • 0029268168 scopus 로고
    • FISH (fluorescent in situ hybridization): The second youth of cytogenetics
    • (1995) Haematologica , vol.80 , pp. 95-97
    • Mecucci, C.1
  • 65
    • 0034665776 scopus 로고    scopus 로고
    • Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: Evidence for involvement at the hematopoietic stem cell level
    • (2000) Blood , vol.96 , pp. 2012-2021
    • Nilsson, L.1    Astrand-Grundstrom, I.2    Arvidsson, I.3
  • 67
    • 0023269281 scopus 로고
    • Cytogenetic characteristics of therapy-related acute nonlymphocytic leukaemia, preleukaemia and acute myeloproliferative syndrome: Correlation with clinical data for 61 consecutive cases
    • (1987) Br J Haematol , vol.66 , pp. 199-207
    • Pedersen-Bjergaard, J.1    Philip, P.2
  • 68
    • 0027413016 scopus 로고
    • Interphase cytogenetics by fluorescent in situ hybridization (FISH) for characterization of monosomy-7-associated myeloid disorders
    • (1993) Leukemia , vol.7 , pp. 384-391
    • Baurmann, H.1    Cherif, D.2    Berger, R.3
  • 74
    • 1842295700 scopus 로고    scopus 로고
    • Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias
    • (1997) Blood , vol.89 , pp. 2036-2041
    • Fisher, K.1    Frohling, S.2    Scherer, S.W.3
  • 76
    • 0032402187 scopus 로고    scopus 로고
    • Molecular cytogenetic characterization of a critical region in bands 7q35-q36 commonly deleted in malignant myeloid disorders
    • (1998) Blood , vol.92 , pp. 4031-4035
    • Dohner, K.1    Brown, J.2    Hehmann, U.3
  • 84
    • 0034177514 scopus 로고    scopus 로고
    • Delineation of a minimal interval and identification of 9 candidates for a tumor suppressor gene in malignant myeloid disorders on 5q31
    • (2000) Blood , vol.95 , pp. 2372-2377
    • Horrigan, S.K.1    Arbieva, Z.H.2    Xie, H.Y.3
  • 85
    • 0032868343 scopus 로고    scopus 로고
    • Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype
    • (1999) Leukemia , vol.3 , pp. 1235-1242
    • Horiike, S.1    Misawa, S.2    Kaneko, H.3
  • 88
    • 0028928283 scopus 로고
    • Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoiesis and a high incidence of p53 mutations
    • (1995) Leukemia , vol.9 , pp. 370-381
    • Lai, J.L.1    Preudhomme, C.2    Zandecki, M.3
  • 90
    • 0028065441 scopus 로고
    • Expression of EVI1 in myelodysplastic syndromes and other hematologic malignancies without 3q26 translocations
    • (1994) Blood , vol.84 , pp. 1243-1248
    • Russell, M.1    List, A.2    Greenberg, P.3
  • 92
    • 0030041634 scopus 로고    scopus 로고
    • Correlation of MLL breakpoints in 11q23 rearrangements with topoisomerase II consensus binding sites, Alu sequences and scaffold attachment regions
    • (1996) Blood , vol.87 , pp. 1912-1922
    • Broeker, P.1    Super, H.G.2    Thirman, M.3
  • 99
    • 0029033747 scopus 로고
    • TEL gene is involved in myelodysplastic syndromes with either the typical t(5;12)(q33;p13) translocation or its variant t(l0,12)(q24;pl3)
    • (1995) Blood , vol.85 , pp. 2848-2852
    • Wlodarska, I.1    Mecucci, C.2    Marynen, P.3
  • 100
    • 4243767542 scopus 로고    scopus 로고
    • H4(D10S170) a gene frequently rearranged in papillary thyroid carcinoma is fused to the platelet-derived growth factor receptor β (PDGFBR) gene in atypical chronic myeloid leukemia with a t(5;10) (q33,q22)
    • (1999) Blood , vol.94 , Issue.SUPPL.1
    • Anastasiadou, E.1    Schwaller, J.2    Sternberg, D.W.3
  • 102
    • 9044251606 scopus 로고    scopus 로고
    • Loss of NF1 results in activation of the Ras signalling pathway and leads to aberrant growth in haematopoietic cells
    • (1996) Nat Genet , vol.12 , pp. 144-148
    • Bollag, G.1    Clapp, D.W.2    Shih, S.3
  • 108
    • 0034654269 scopus 로고    scopus 로고
    • Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: Potential prognostic implications
    • (2000) Blood , vol.95 , pp. 1942-1949
    • Wong, I.H.1    Ng, M.H.2    Huang, D.P.3    Lee, J.C.4
  • 112
    • 85084726874 scopus 로고
    • Subcutaneous erythropoietin for treatment of refractory anemia in hematologic disorders
    • (1992) Blood , vol.80 , pp. 841-843
    • Cazzola, M.1    Ponchio, L.2
  • 117
    • 0027304592 scopus 로고
    • Treatment of the anaemia of myelodysplastic syndromes using human granulocyte-CSF in combination with erythropoietin
    • (1993) Blood , vol.82 , pp. 737-743
    • Negrin, R.S.1    Stein, R.2    Doherty, K.3
  • 119
    • 0029940725 scopus 로고    scopus 로고
    • Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: Evidence for in vivo synergy
    • (1996) Blood , vol.87 , pp. 4076-4081
    • Negrin, R.S.1    Stein, R.2    Doherty, K.3
  • 121
    • 0028050695 scopus 로고
    • Trilineage recovery by combination therapy with recombinant human granulocyte colony-stimulating factor and erythropoietin in patients with aplastic anemia and refractory anemia
    • (1994) Stem Cells , vol.12 , pp. 604-615
    • Bessho, M.1    Jinnai, I.2    Hirashima, K.3
  • 125
    • 0001204341 scopus 로고
    • Combined treatment of myelodysplastic syndromes (MDS) with recombinant human Interleukin 3 and erythropoietin (EPO)
    • (1994) Blood , vol.84 , Issue.SUPPL. 1
    • List, A.L.1    Noyes, W.2    Power, J.3
  • 136
    • 0030729822 scopus 로고    scopus 로고
    • Autologous bone marrow transplantation for patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia following MDS
    • Chronic and Acute Leukemia Working Parties of the European Group for Blood and Marrow Transplantation
    • (1997) Blood , vol.90 , pp. 3853-3857
    • De Witte, T.1    Van Biezen, A.2    Hermans, J.3
  • 137
    • 0028861053 scopus 로고
    • Intensive chemotherapy for poor prognosis myelodysplasia (MDS) and secondary acute myeloid leukemia (sAML) following MDS of more than 6 months duration. A pilot study by the Leukemia Cooperative Group of the European Organisation for Research and Treatment in Cancer (EORTC-LCG)
    • (1995) Leukemia , vol.9 , pp. 1805-1811
    • De Witte, T.1    Suciu, S.2    Peetermans, M.3
  • 138
    • 0028805708 scopus 로고
    • Polyclonal primitive hematopoietic progenitors can be detected in mobilized peripheral blood from patients with high-risk myelodysplastic syndromes
    • (1995) Blood , vol.86 , pp. 3660-3667
    • Delforge, M.1    Demuynck, H.2    Vandenberghe, P.3
  • 139
    • 10244260460 scopus 로고    scopus 로고
    • In vivo mobilization of karyotypically normal peripheral blood progenitor cells in high-risk MDS, secondary or therapy-related acute myelogenous leukemia
    • (1996) Br J Haematol , vol.95 , pp. 127-130
    • Carella, A.M.1    Dejana, A.2    Lerma, E.3
  • 140
    • 0023352145 scopus 로고
    • Low-dose ARA-C in acute nonlymphocytic leukemia and myelodysplastic syndromes: A review of 20 years experience
    • (1987) Semin Oncol , vol.14 , pp. 126-133
    • Cheson, B.D.1    Simon, R.2
  • 146
    • 10144234806 scopus 로고    scopus 로고
    • Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia
    • (1996) Blood , vol.88 , pp. 2473-2479
    • Beran, M.1    Kantarjian, H.2    O'Brien, S.3
  • 150
  • 151
    • 0029743347 scopus 로고    scopus 로고
    • Intensive chemotherapy in childhood myelodysplastic syndrome: A comparison with results in acute myeloid leukemia
    • (1996) Leukemia , vol.10 , pp. 1269-1273
    • Hasle, H.1    Kerndrup, G.2    Yssing, M.3
  • 152
    • 0029737359 scopus 로고    scopus 로고
    • Acute myeloid leukemia-type chemotherapy for newly diagnosed patients without antecedent cytopenias having myelodysplastic syndrome as defined by French-American-British criteria: A Cancer and Leukemia Group B study
    • (1996) J Clin Oncol , vol.14 , pp. 2486-2494
    • Bernstein, S.H.1    Brunetto, V.L.2    Davey, F.R.3
  • 158
    • 0032884937 scopus 로고    scopus 로고
    • Topotecan and cytarabine is an active combination regimen in myelodysplastic syndromes and chronic myelomonocytic leukemia
    • (1999) J Clin Oncol , vol.17 , pp. 2819-2830
    • Beran, M.1    Estey, E.2    O'Brien, S.3
  • 160
    • 7344227279 scopus 로고    scopus 로고
    • Quinine improves the results of intensive chemotherapy in myelodysplastic syndromes expressing P-glycoprotein: Results of a randomized study
    • (1998) Br J Haematol , vol.102 , pp. 1015-1024
    • Wattel, E.1    Solary, E.2    Hecquet, B.3
  • 163
    • 0028344644 scopus 로고
    • Use of granulocyte colony-stimulating factor before, during, and after fludarabine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes: Comparison with fludarabine plus cytarabine without granulocyte colony-stimulating factor
    • (1994) J Clin Oncol , vol.12 , pp. 671-678
    • Estey, E.1    Thall, P.2    Andreeff, M.3
  • 167
    • 0033776686 scopus 로고    scopus 로고
    • Haemopoietic stem cell transplantation for patients with myelodysplastic syndromes and secondary acute leukaemias: A report on behalf of the Chronic Leukaemia Working Party of the European Groups for Blood and Marrow Transplantation
    • (2000) Br J Haematol , vol.110 , pp. 620-630
    • De Witte, T.1    Hermans, J.2    Vossen, J.3
  • 168
  • 170
    • 0031961981 scopus 로고    scopus 로고
    • Bone marrrow transplantation from HLA identical siblings as first line treatment in patients with myelodysplastic syndromes: Early transplantation is associated with improved outcome
    • The Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)
    • (1998) Bone Marrow Transplant , vol.21 , pp. 255-261
    • Runde, V.1    De Witte, T.2    Arnold, R.3
  • 171
    • 18844465770 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation for chronic myelomonocytic leukemia in chidhood: A report from the European Working Group on Myelodysplastic Syndrome in Childhood
    • (1997) J Clin Oncol , vol.15 , pp. 566
    • Locatelli, F.1    Niemeyner, C.2    Angelucci, E.3
  • 175
    • 0025073138 scopus 로고
    • Allogeneic bone marrow transplantation for secondary leukaemia and myelodysplastic syndrome: A survey by the Leukaemia Working Party of the European Bone Marrow Transplantation Group (EBMTG)
    • (1990) Br J Haematol , vol.74 , pp. 151-155
    • De Witte, T.1    Zwaan, F.2    Hermans, J.3
  • 182
  • 185
    • 0030069853 scopus 로고    scopus 로고
    • Allogeneic marrow transplantation for myelodysplastic syndrome with advanced disease morphology: A phase II study of busulfan, cyclophosphamide, and total-body irradiation and analysis of prognostic factors
    • (1996) J Clin Oncol , vol.14 , pp. 220-226
    • Anderson, J.E.1    Appelbaum, F.R.2    Schoch, G.3
  • 189
    • 0030945938 scopus 로고    scopus 로고
    • Stem cell transplantation for secondary acute myeloid leukemia: Evaluation of transplantation as initial therapy or following induction chemotherapy
    • (1997) Blood , vol.89 , pp. 2578-2585
    • Anderson, J.E.1    Gooley, T.A.2    Schoch, G.3
  • 191
    • 0032531067 scopus 로고    scopus 로고
    • Cytogenetic abnormalities in primary myelodysplastic syndromes are highly predictive of outcome after allogeneic bone marrow transplantation
    • (1998) Blood , vol.92 , pp. 1910-1917
    • Nevill, T.J.1    Fung, H.C.2    Sheperd, J.D.3
  • 192
    • 8944243549 scopus 로고    scopus 로고
    • Factors influencing outcome in de novo myelodysplastic syndromes treated by allogeneic bone marrow transplantation: A long term study of 71 patients
    • Societè Française de Greffe de Moelle
    • (1996) Blood , vol.88 , pp. 358-365
    • Sutton, L.1    Chastang, C.2    Ribaud, P.3
  • 193
    • 0032006125 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and non malignant hematologic disease
    • (1998) Blood , vol.91 , pp. 756-763
    • Slavin, S.1    Nagler, A.2    Naparstek, E.3
  • 206
    • 8944224533 scopus 로고    scopus 로고
    • Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2
    • (1996) Blood , vol.87 , pp. 5218-5224
    • Ho, C.Y.1    Otterud, B.2    Legare, R.D.3
  • 210
    • 0030977399 scopus 로고    scopus 로고
    • Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases
    • European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS)
    • (1997) Blood , vol.89 , pp. 3534-3543
    • Niemeyer, C.M.1    Aricò, M.2    Basso, G.3
  • 212
    • 0021233189 scopus 로고
    • Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors
    • (1984) Cancer , vol.54 , pp. 675-686
    • Castro-Malaspina, H.1    Schaison, G.2    Passe, S.3
  • 221
    • 0032400865 scopus 로고    scopus 로고
    • Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia
    • (1998) Blood , vol.92 , pp. 4279-4286
    • Frankel, A.E.1    Lilly, M.2    Kreitman, R.3
  • 222
    • 0032402145 scopus 로고    scopus 로고
    • Modulation of granulocyte-macrophage colony-stimulating factor gene expression by a tumor necrosis factor specific ribozyme in juvenile myelomonocytic leukemic cells
    • (1998) Blood , vol.92 , pp. 4263-4268
    • Iversen, P.O.1    Sioud, M.2
  • 223
    • 0025244911 scopus 로고
    • The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae
    • (1990) Cell , vol.63 , pp. 835-841
    • Xu, G.F.1    Lin, B.2    Tanaka, K.3
  • 224
    • 0028069689 scopus 로고
    • The NF1 gene in myelopoiesis and childhood myelodysplastic syndromes
    • (1994) N Engl J Med , vol.330 , pp. 637-639
    • Brodeur, G.M.1
  • 226
    • 0032125716 scopus 로고    scopus 로고
    • Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1
    • (1998) Blood , vol.92 , pp. 267-272
    • Side, L.E.1    Emanuel, P.D.2    Taylor, B.3
  • 229
    • 0023888449 scopus 로고
    • Recommendations for a morphologic, immunologic, and cytogenetic (MIC) working classification of the primary and therapy-related myelodysplastic disorders. Report of the workshop held in Scottsdale, Arizona, USA, on February 23-25, 1987
    • Third MIC Cooperative Study Group
    • (1988) Cancer Genet Cytogenet , vol.32 , pp. 1-10
  • 231
    • 0038592646 scopus 로고    scopus 로고
    • AML-type intensive chemotherapy prior to stem cell transplantation (SCT) does not improve survival in children and adolescents with primary myelodysplastic syndromes (MDS)
    • (2000) Blood , vol.96 , Issue.SUPPL. 1
    • Niemeyer, C.1    Duffner, U.2    Bender-Gotze, C.3
  • 232
    • 0027218793 scopus 로고
    • Intensively timed induction therapy followed by autologous or allogeneic bone marrow transplantation for children with acute myeloid leukemia or myelodysplastic syndrome: A Childrens' Cancer Group pilot study
    • (1993) J Clin Oncol , vol.11 , pp. 1448-1457
    • Woods, W.G.1    Kobrinsky, N.2    Buckley, J.3
  • 237
    • 9044245304 scopus 로고    scopus 로고
    • Role of allogeneic bone marrow transplantation from HLA-identical sibling or a matched unrelated donor in the treatment of children with juvenile chronic myeloid leukaemia
    • (1996) Br J Haematol , vol.92 , pp. 49-54
    • Locatelli, F.1    Pession, A.2    Comoli, P.3
  • 238
    • 0029073949 scopus 로고
    • Role of busulfan and total body irradiation on growth of prepubertal children receiving bone marrow transplantation and results of treatment with recombinant human growth hormone
    • (1995) Blood , vol.86 , pp. 825-831
    • Giorgiani, G.1    Bozzola, M.2    Locatelli, F.3
  • 239
    • 0032858568 scopus 로고    scopus 로고
    • Beyond the FAB classification for myelodysplastic syndromes
    • (1999) Haematologica , vol.84 , pp. 1-2
  • 242
    • 0033139799 scopus 로고    scopus 로고
    • The pathogenesis and management of essential thrombocythaemia
    • EHA4 Educational Book
    • (1999) Haematologica , vol.84 , pp. 36-39
    • Green, A.R.1
  • 244
    • 0032737477 scopus 로고    scopus 로고
    • Treatment of myelodysplastic syndromes
    • (1999) Haematologica , vol.84 , pp. 962
  • 246
    • 0033390226 scopus 로고    scopus 로고
    • Combined use of erythropoietin and G-CSF in the treatment of myelodysplastic syndromes
    • (1999) Haematologica , vol.84 , pp. 1057
  • 247
    • 17544392895 scopus 로고    scopus 로고
    • Erythropoietin plus granulocyte colony-stimulating factor in the treatment of myelodysplastic syndromes. Identification of a subgroup of responders
    • The Spanish Erythropathology Group
    • (1999) Haematologica , vol.84 , pp. 1058-1064
    • Remacha, A.F.1    Arrizabalaga, B.2    Villegas, A.3
  • 248
    • 0033974579 scopus 로고    scopus 로고
    • The molecular basis of paroxysmal nocturnal hemoglobinuria
    • (2000) Haematologica , vol.85 , pp. 82-87
    • Rosti, V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.