Scutellariae radix extracts suppress ethanol-induced caspase-11 expression and cell death in N2a cells

Molecular Brain Research

Volumn 142, Issue 2, 2005, Pages 139-145

  Kang, Kyounglan ^a   Oh, Yeo Kyoung ^b   Choue, Ryowon ^a   Kang, Shin Jung ^b  

^a Kyung Hee University   (South Korea)

^b Sejong University   (South Korea)

Author keywords

Apoptosis; Caspase 11; Ethanol; N2a neuroblastoma; Scutellariae radix

Indexed keywords

CASPASE 11; SCUTELLARIAE RADIX;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; DRUG EFFECT; DRUG MECHANISM; EMBRYO CELL; ENZYME ACTIVATION; FIBROBLAST; MOUSE; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, WESTERN; CASPASES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; EMBRYO; ENZYME INDUCTION; ENZYME INHIBITORS; ETHANOL; FIBROBLASTS; GENE EXPRESSION REGULATION; IN SITU NICK-END LABELING; MICE; NEUROBLASTOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SCUTELLARIA BAICALENSIS;

ANIMALIA; SCUTELLARIAE RADIX;

EID: 27944446104     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2005.09.006     Document Type: Article

References (25)

1. Z.F. Cheema, J.R. West, and R.C. Miranda Ethanol induces Fas/Apo [apoptosis]-1 mRNA and cell suicide in the developing cerebral cortex Alcohol.: Clin. Exp. Res. 24 2000 535 543
2. J. Choi, C.C. Conrad, C.A. Malakowsky, J.M. Talent, C.S. Yuan, and R.W. Gracy Flavones from Scutellaria baicalensis Georgi attenuate apoptosis and protein oxidation in neuronal cell lines Biochim. Biophys. Acta 1571 2002 201 210
3. S.M. de la Monte, T.R. Neely, J. Cannon, and J.R. Wands Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons Cell. Mol. Life Sci. 58 2001 1950 1960
4. Z. Gao, K. Huang, X. Yang, and H. Xu Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi Biochim. Biophys. Acta 1472 1999 643 650
5. X. Gong, and N.J. Sucher Stroke therapy in traditional Chinese medicine (TCM): prospects for drug discovery and development Trends Pharmacol. Sci. 20 1999 191 196
6. S.J. Kang, S. Wang, H. Hara, E.P. Peterson, S. Namura, S. Amin-Hanjani, Z. Huang, A. Srinivasan, K.J. Tomaselli, N.A. Thornberry, M.A. Moskowitz, and J. Yuan Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions J. Cell Biol. 149 2000 613 622
7. S.J. Kang, S. Wang, K. Kuida, and J. Yuan Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response Cell Death Differ. 9 2002 1115 1125
8. S. Kamada, M. Washida, J. Hasegawa, H. Kusano, Y. Funahashi, and Y. Tsujimoto Involvement of caspase-4 (-like) protease in Fas-mediated apoptotic pathway Oncogene 15 1997 285 290
9. Y.O. Kim, K. Leem, J. Park, P. Lee, D.K. Ahn, B.C. Lee, H.K. Park, K. Suk, S.Y. Kim, and H. Kim Cytoprotective effect of Scutellaria baicalensis in CA1 hippocampal neurons of rats after global cerebral ischemia J. Ethnopharmacol. 77 2001 183 188
10. M. Kobori, Z. Yang, D. Gong, V. Heissmeyer, H. Zhu, Y.K. Jung, M.A. Gakidis, A. Rao, T. Sekine, F. Ikegami, C. Yuan, and J. Yuan Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex Cell Death Differ. 11 2004 123 130
11. H. Lee, Y.O. Kim, H. Kim, S.Y. Kim, H.S. Noh, S.S. Kang, G.J. Cho, W.S. Choi, and K. Suk Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia FASEB J. 17 2003 1943 1944
12. X.Y. Lin, M.S. Choi, and A.G. Porter Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma J. Biol. Chem. 275 2000 39920 39926
13. F. Martinon, K. Burns, and J. Tschopp The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-1beta Mol. Cell 10 2002 417 426
14. P.A. Melo, M.C. do Nascimento, W.B. Mors, and G. Suarez-Kurtz Inhibition of the myotoxic and hemorrhagic activities of crotalid venoms by Eclipta prostrata (Asteraceae) extracts and constituents Toxicon 32 1994 595 603
15. J.W. Olney, D.F. Wozniak, N.B. Farber, V. Jevtovic-Todorovic, P. Bittigau, and C. Ikonomidou The enigma of fetal alcohol neurotoxicity Ann. Med. 34 2002 109 119
16. M. Pascual, S.L. Valles, J. Renau-Piqueras, and C. Guerri Ceramide pathways modulate ethanol-induced cell death in astrocytes J. Neurochem. 87 2003 1535 1545
17. V. Ramachandran, A. Perez, J. Chen, D. Senthil, S. Schenker, and G.I. Henderson In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain: a potential role for 4-hydroxynonenal Alcohol.: Clin. Exp. Res. 25 2001 862 871
18. V. Ramachandran, L.T. Watts, S.K. Maffi, J. Chen, S. Schenker, and G. Henderson Ethanol-induced oxidative stress precedes mitochondrially mediated apoptotic death of cultured fetal cortical neurons J. Neurosci. Res. 74 2003 577 588
19. R. Schauvliege, J. Vanrobaeys, P. Schotte, and R. Beyaert Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-kappa B and signal transducer and activator of transcription (STAT) J. Biol. Chem. 277 2002 41624 41630
20. D.E. Shieh, L.T. Liu, and C.C. Lin Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin Anticancer Res. 20 2000 2861 2865
21. K. Suk, H. Lee, S.S. Kang, G.J. Cho, and W.S. Choi Flavonoid baicalein attenuates activation-induced cell death of brain microglia J. Pharmacol. Exp. Ther. 305 2003 638 645
22. M. Van Die, K. Takahashi, M.M. Mu, N. Koide, T. Sugiyama, I. Mori, T. Yoshida, and T. Yokochi Protective effect of wogonin on endotoxin-induced lethal shock in D-galactosamine-sensitized mice Microbiol. Immunol. 45 2001 751 756
23. H. Wagner, B. Geyer, Y. Kiso, H. Hikino, and G.S. Rao Coumestans as the main active principles of the liver drugs Eclipta alba and Wedelia calendulacea Planta Med. 52 1986 370 374
24. S.S. Wang, M. Miura, Y. Jung, H. Zhu, V. Gagliardini, L. Shi, A.H. Greenberg, and J. Yuan Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE J. Biol. Chem. 271 1996 20580 20587
25. S. Wang, M. Miura, Y.K. Jung, H. Zhu, E. Li, and J. Yuan Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE Cell 92 1998 501 509