메뉴 건너뛰기




Volumn 591, Issue 1-2, 2005, Pages 187-197

The role of human adult stem cells and cell-cell communication in cancer chemoprevention and chemotherapy strategies

Author keywords

Adult human stem cells; Cancer stem cells; Chemoprevention; Chemotherapy; Gap junctional intercellular communication; Oct 4 gene

Indexed keywords

CAFFEIC ACID; ESTER DERIVATIVE; PROTEIN INHIBITOR; RESVERATROL;

EID: 27844610799     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2005.01.034     Document Type: Article
Times cited : (19)

References (58)
  • 2
    • 0025892213 scopus 로고
    • Facts and theories concerning the mechanisms of carcinogenesis
    • H.C. Pitot, and Y.P. Dragan Facts and theories concerning the mechanisms of carcinogenesis FASEB J. 5 1991 2280 2286
    • (1991) FASEB J. , vol.5 , pp. 2280-2286
    • Pitot, H.C.1    Dragan, Y.P.2
  • 3
    • 0002179233 scopus 로고    scopus 로고
    • Intercellular communication: A paradigm for the interpretation of the initiation/promotion/progress model of carcinogenesis
    • J.C. Arcos Birkkhauser Boston, MA
    • J.E. Trosko, C.C. Chang, B.V. Madhukar, and E. Dupont Intercellular communication: a paradigm for the interpretation of the initiation/promotion/ progress model of carcinogenesis J.C. Arcos Chemical Induction of Cancer: Modulation and Combination Effects 1996 Birkkhauser Boston, MA 205 225
    • (1996) Chemical Induction of Cancer: Modulation and Combination Effects , pp. 205-225
    • Trosko, J.E.1    Chang, C.C.2    Madhukar, B.V.3    Dupont, E.4
  • 4
    • 1942471702 scopus 로고    scopus 로고
    • Epigenetics and cancer: Implications for drug discovery and safety assessment
    • J.G. Moggs, J.I. Goodman, J.E. Trosko, and R.A. Roberts Epigenetics and cancer: implications for drug discovery and safety assessment Toxicol. Appl. Pharmacol. 196 2004 422 430
    • (2004) Toxicol. Appl. Pharmacol. , vol.196 , pp. 422-430
    • Moggs, J.G.1    Goodman, J.I.2    Trosko, J.E.3    Roberts, R.A.4
  • 5
    • 0000299698 scopus 로고    scopus 로고
    • Cell-cell communication in carcinogenesis
    • J.E. Trosko, and R.J. Ruch. Cell-cell communication in carcinogenesis Front. Biosci. 3 1998 208 236
    • (1998) Front. Biosci. , vol.3 , pp. 208-236
    • Trosko, J.E.1    Ruch., R.J.2
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 0018149578 scopus 로고
    • Phenotypic diversity in experimental hepatomas: The concept of partially blocked ontogeny
    • V.R. Potter Phenotypic diversity in experimental hepatomas: the concept of partially blocked ontogeny Br. J. Cancer 38 1978 1 23
    • (1978) Br. J. Cancer , vol.38 , pp. 1-23
    • Potter, V.R.1
  • 9
    • 0014014672 scopus 로고
    • Permeability of membrane junctions
    • W.R. Loewenstein Permeability of membrane junctions Ann. N. Y. Acad. Sci. 137 1966 441 472
    • (1966) Ann. N. Y. Acad. Sci. , vol.137 , pp. 441-472
    • Loewenstein, W.R.1
  • 10
    • 0037530140 scopus 로고    scopus 로고
    • The role of stem cells and gap junctional intercellular communication in carcinogenesis
    • J.E. Trosko The role of stem cells and gap junctional intercellular communication in carcinogenesis J. Biochem. Mol. Biol. 36 2003 43 48
    • (2003) J. Biochem. Mol. Biol. , vol.36 , pp. 43-48
    • Trosko, J.E.1
  • 11
    • 0019792243 scopus 로고
    • The natural history of carcinogenesis: Implications of experimental carcinogenesis in the genesis of human cancer
    • H.C. Pitot, T.L. Goldsworthy, and S. Moran The natural history of carcinogenesis: implications of experimental carcinogenesis in the genesis of human cancer J. Supramol. Struct. Cell Biochem. 17 1981 133 146
    • (1981) J. Supramol. Struct. Cell Biochem. , vol.17 , pp. 133-146
    • Pitot, H.C.1    Goldsworthy, T.L.2    Moran, S.3
  • 12
    • 0000179727 scopus 로고
    • Carcinogens as mutagens: A simple test combining liver homogenates for activation and bacteria for detection
    • B.N. Ames, W.E. Durston, E. Yamasaki, and F.D. Lee Carcinogens as mutagens: a simple test combining liver homogenates for activation and bacteria for detection Proc. Natl. Acad. Sci. U.S.A. 70 1973 2281 2285
    • (1973) Proc. Natl. Acad. Sci. U.S.A. , vol.70 , pp. 2281-2285
    • Ames, B.N.1    Durston, W.E.2    Yamasaki, E.3    Lee, F.D.4
  • 13
    • 0030701583 scopus 로고    scopus 로고
    • Challenge to the simple paradigm that "carcinogens" are "mutagens" and to the in vitro and in vivo assays used to test the paragdigm
    • J.E. Trosko Challenge to the simple paradigm that "carcinogens" are "mutagens" and to the in vitro and in vivo assays used to test the paragdigm Mutat. Res. 373 1997 245 249
    • (1997) Mutat. Res. , vol.373 , pp. 245-249
    • Trosko, J.E.1
  • 14
    • 0037716639 scopus 로고    scopus 로고
    • Have environmental mutagens caused oncomutations in people?
    • W.G. Thilly Have environmental mutagens caused oncomutations in people? Nat. Genet. 34 2003 255 259
    • (2003) Nat. Genet. , vol.34 , pp. 255-259
    • Thilly, W.G.1
  • 15
    • 0035061652 scopus 로고    scopus 로고
    • Commentary: Is the concept of "tumor promotion" a useful paradigm?
    • J.E. Trosko Commentary: is the concept of "tumor promotion" a useful paradigm? Mol. Carcinog. 30 2001 131 137
    • (2001) Mol. Carcinog. , vol.30 , pp. 131-137
    • Trosko, J.E.1
  • 18
    • 0031935856 scopus 로고    scopus 로고
    • Bay and baylike regions of polycyclic aromatic hydrocarbons were potent inhibitors of gap junctional of gap junctional intercellular communication
    • L.M. Weis, A.M. Rummel, S.J. Masten, J.E. Trosko, and B.L. Upham Bay and baylike regions of polycyclic aromatic hydrocarbons were potent inhibitors of gap junctional of gap junctional intercellular communication Environ. Health Perspect. 106 1998 17 22
    • (1998) Environ. Health Perspect. , vol.106 , pp. 17-22
    • Weis, L.M.1    Rummel, A.M.2    Masten, S.J.3    Trosko, J.E.4    Upham, B.L.5
  • 19
    • 0031686703 scopus 로고    scopus 로고
    • Modulated gap junctional intercellular communication as a biomarker of PAH epigenetic toxicity: Structure-function relationship
    • B.L. Upham, L.M. Weis, and J.E. Trosko Modulated gap junctional intercellular communication as a biomarker of PAH epigenetic toxicity: structure-function relationship Environ. Health Perspect. 106 1998 975 988
    • (1998) Environ. Health Perspect. , vol.106 , pp. 975-988
    • Upham, B.L.1    Weis, L.M.2    Trosko, J.E.3
  • 20
    • 0033001404 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons with bay-like regions inhibited gap junctional intercellular communication and stimulated MAPK activity
    • A.M. Rummel, J.E. Trosko, M.R. Wilson, and B.L. Upham Polycyclic aromatic hydrocarbons with bay-like regions inhibited gap junctional intercellular communication and stimulated MAPK activity Toxicol. Sci. 49 1999 232 240
    • (1999) Toxicol. Sci. , vol.49 , pp. 232-240
    • Rummel, A.M.1    Trosko, J.E.2    Wilson, M.R.3    Upham, B.L.4
  • 21
    • 0036890347 scopus 로고    scopus 로고
    • Gap junctions as targets for cancer chemoprevention and chemotherapy
    • J.E. Trosko, and R.J. Ruch Gap junctions as targets for cancer chemoprevention and chemotherapy Curr. Drug Targets 3 2003 465 482
    • (2003) Curr. Drug Targets , vol.3 , pp. 465-482
    • Trosko, J.E.1    Ruch, R.J.2
  • 22
    • 0018723692 scopus 로고
    • Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter
    • L.P. Yotti, C.C. Chang, and J.E. Trosko Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter Science 206 1979 1089 1091
    • (1979) Science , vol.206 , pp. 1089-1091
    • Yotti, L.P.1    Chang, C.C.2    Trosko, J.E.3
  • 23
    • 0002913402 scopus 로고
    • Oncogenes, tumor suppressor genes and intercellular communication in the 'Oncogeny as partially blocked ontogeny' hypothesis
    • O.H. Iversen Taylor & Francis Publishers Washington, DC
    • J.E. Trosko, C.C. Chang, B.V. Madhukar, and E. Dupont Oncogenes, tumor suppressor genes and intercellular communication in the 'Oncogeny as partially blocked ontogeny' hypothesis O.H. Iversen New Frontiers in Cancer Causation 1993 Taylor & Francis Publishers Washington, DC 181 197
    • (1993) New Frontiers in Cancer Causation , pp. 181-197
    • Trosko, J.E.1    Chang, C.C.2    Madhukar, B.V.3    Dupont, E.4
  • 24
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • H. Land, L.F. Parada, and R.A. Weinberg Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes Nature 304 1983 596 602
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 25
    • 0034091069 scopus 로고    scopus 로고
    • Gap junctions and the regulation of cellular function of stem cells during development and differentiation
    • J.E. Trosko, C.C. Chang, M.R. Wilson, B.L. Upham, T. Hayashi, and M. Wade Gap junctions and the regulation of cellular function of stem cells during development and differentiation Methods 20 2000 245 264
    • (2000) Methods , vol.20 , pp. 245-264
    • Trosko, J.E.1    Chang, C.C.2    Wilson, M.R.3    Upham, B.L.4    Hayashi, T.5    Wade, M.6
  • 26
    • 0029991014 scopus 로고    scopus 로고
    • Telomerase activity in human cancer
    • J.W. Shay, and W.E. Wright Telomerase activity in human cancer Curr. Opin. Oncol. 8 1996 66 71
    • (1996) Curr. Opin. Oncol. , vol.8 , pp. 66-71
    • Shay, J.W.1    Wright, W.E.2
  • 27
  • 30
    • 1642474273 scopus 로고    scopus 로고
    • Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
    • T. Kondo, T. Setoguchi, and T. Taga Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line Proc. Natl. Acad. Sci. U.S.A. 101 2004 781 786
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 781-786
    • Kondo, T.1    Setoguchi, T.2    Taga, T.3
  • 32
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myloid progenitors
    • A. Cozzio, E. Passegue, P.M. Ayton, H. Karsunky, M.L. Cleary, and I.L. Weissman Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myloid progenitors Genes Dev. 17 2003 3029 3035
    • (2003) Genes Dev. , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 33
    • 0037386583 scopus 로고    scopus 로고
    • Breast cancer stem cells revealed
    • J.E. Dick Breast cancer stem cells revealed Proc. Natl. Acad. Sci. U.S.A. 100 2003 3547 3549
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 3547-3549
    • Dick, J.E.1
  • 35
    • 0035991948 scopus 로고    scopus 로고
    • Gap junctions: Structure and function (Review)
    • W.H. Evans, and E.M. Martin-Patricia Gap junctions: structure and function (Review) Mol. Membr. Biol. 19 2002 121 136
    • (2002) Mol. Membr. Biol. , vol.19 , pp. 121-136
    • Evans, W.H.1    Martin-Patricia, E.M.2
  • 36
    • 0023142481 scopus 로고
    • Contact insensitivity of a subpopulation of normal human fetal kidney epithelial cells and of human carcinoma cell lines
    • C.C. Chang, J.E. Trosko, M.H. El-Fouly, D.R. Gibson, and S.M. D'Ambrosio Contact insensitivity of a subpopulation of normal human fetal kidney epithelial cells and of human carcinoma cell lines Cancer Res. 47 1987 1634 1645
    • (1987) Cancer Res. , vol.47 , pp. 1634-1645
    • Chang, C.C.1    Trosko, J.E.2    El-Fouly, M.H.3    Gibson, D.R.4    D'Ambrosio, S.M.5
  • 37
    • 0028951698 scopus 로고
    • Two types of normal human breast epithelial cells derived from reduction mammoplasty: Phenotypic characterization and response to SV40 transfection
    • C.Y. Kao, K. Nomata, C.S. Oakley, C.W. Welsch, and C.C. Chang Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and response to SV40 transfection Carcinogenesis 16 1995 531 538
    • (1995) Carcinogenesis , vol.16 , pp. 531-538
    • Kao, C.Y.1    Nomata, K.2    Oakley, C.S.3    Welsch, C.W.4    Chang, C.C.5
  • 38
    • 0037208677 scopus 로고    scopus 로고
    • Characterization of gap junctional intercellular communication in immortalized human ductal epithelial cells with stem cell characteristics
    • M.H. Tai, B.V. Madhukar, L.K. Olson, K.D. Linning, L. VanCamp, M.S. Tsao, and J.E. Trosko Characterization of gap junctional intercellular communication in immortalized human ductal epithelial cells with stem cell characteristics Pancreas 26 2003 e18 e26
    • (2003) Pancreas , vol.26
    • Tai, M.H.1    Madhukar, B.V.2    Olson, L.K.3    Linning, K.D.4    Vancamp, L.5    Tsao, M.S.6    Trosko, J.E.7
  • 39
    • 27844473721 scopus 로고    scopus 로고
    • personal communication.
    • C.C. Chang, personal communication.
    • Chang, C.C.1
  • 41
    • 0036272367 scopus 로고    scopus 로고
    • Human limbal progenitor cells expanded on intact amniotic membrane ex vivo
    • M. Grueterich, and S.C.G. Tseng Human limbal progenitor cells expanded on intact amniotic membrane ex vivo Arch. Ophthalmol. 120 2002 783 790
    • (2002) Arch. Ophthalmol. , vol.120 , pp. 783-790
    • Grueterich, M.1    Tseng, S.C.G.2
  • 42
    • 0036151186 scopus 로고    scopus 로고
    • Epidermal stem cells do not communicate through gap junctions
    • M. Matic, W.H. Evans, P.R. Brink, and M. Simon Epidermal stem cells do not communicate through gap junctions J. Invest. Dermatol. 118 2002 110 116
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 110-116
    • Matic, M.1    Evans, W.H.2    Brink, P.R.3    Simon, M.4
  • 43
    • 0031955441 scopus 로고    scopus 로고
    • No evidence for cell-to-cell coupling in rat colonic crypts: Studies with Lucifer Yellow and with photobleaching
    • C. Jacobi, J. Leipziger, R. Nitschke, S. Ricken, and R. Greger No evidence for cell-to-cell coupling in rat colonic crypts: studies with Lucifer Yellow and with photobleaching Pflugers Arch. Eur. J. Physiol. 436 1998 83 89
    • (1998) Pflugers Arch. Eur. J. Physiol. , vol.436 , pp. 83-89
    • Jacobi, C.1    Leipziger, J.2    Nitschke, R.3    Ricken, S.4    Greger, R.5
  • 44
    • 0041868096 scopus 로고    scopus 로고
    • Label-retaining cells (presumptive stem cells) of mice vibrissae do not express gap junction protein connexin 43
    • M. Matic, and M. Simon Label-retaining cells (presumptive stem cells) of mice vibrissae do not express gap junction protein connexin 43 J. Invest. Dermatol. Symp. Proc. 8 2003 91 95
    • (2003) J. Invest. Dermatol. Symp. Proc. , vol.8 , pp. 91-95
    • Matic, M.1    Simon, M.2
  • 45
    • 0018709823 scopus 로고
    • Gap junctional communication in the preimplantation mouse embryo
    • C.W. Lo, and N.B. Gilula Gap junctional communication in the preimplantation mouse embryo Cell 18 1979 399 409
    • (1979) Cell , vol.18 , pp. 399-409
    • Lo, C.W.1    Gilula, N.B.2
  • 46
    • 0034763554 scopus 로고    scopus 로고
    • Extracellular signaling through the microenvironment: A hypothesis relating carcinogenesis, bystander effects, and genomic instability
    • M.H. Barcellos-Hoff, and A.L. Brooks Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability Radiat. Res. 156 2001 618 627
    • (2001) Radiat. Res. , vol.156 , pp. 618-627
    • Barcellos-Hoff, M.H.1    Brooks, A.L.2
  • 47
    • 13844283358 scopus 로고    scopus 로고
    • Redox-mediated enrichment of self-renewing adult human pancreatic cells which possesses endocrine differentiation potential.
    • K.D. Linning, M.H. Tai, B.V. Madhukar, C.C. Chang, D.N. Reed, S. Ferber, J.E. Trosko, and L.K. Olson Redox-mediated enrichment of self-renewing adult human pancreatic cells which possesses endocrine differentiation potential. Pancreas 29 2004 e64 e76
    • (2004) Pancreas , vol.29
    • Linning, K.D.1    Tai, M.H.2    Madhukar, B.V.3    Chang, C.C.4    Reed, D.N.5    Ferber, S.6    Trosko, J.E.7    Olson, L.K.8
  • 48
    • 0033952366 scopus 로고    scopus 로고
    • Correlation between growth control, neoplastic potential and endogenous connexin43 expression in HeLa cell lines: Implications for tumor progression
    • T.J. King, L.H. Fukushima, T.A. Donlon, A.D. Hieber, K.A. Shimabukuro, and J.S. Bertram Correlation between growth control, neoplastic potential and endogenous connexin43 expression in HeLa cell lines: Implications for tumor progression Carcinogenesis 21 2000 311 315
    • (2000) Carcinogenesis , vol.21 , pp. 311-315
    • King, T.J.1    Fukushima, L.H.2    Donlon, T.A.3    Hieber, A.D.4    Shimabukuro, K.A.5    Bertram, J.S.6
  • 49
    • 0038301986 scopus 로고    scopus 로고
    • Connexin26-mediated gap junctional communication reverses the malignant phenotype of MCF-7 breast cancer cells
    • M. Momiyama, Y. Omori, Y. Ishizaki, Y. Nishikawa, T. Tokairin, J.-I. Ogawa, and K. Enomoto Connexin26-mediated gap junctional communication reverses the malignant phenotype of MCF-7 breast cancer cells Cancer Sci. 94 2003 501 507
    • (2003) Cancer Sci. , vol.94 , pp. 501-507
    • Momiyama, M.1    Omori, Y.2    Ishizaki, Y.3    Nishikawa, Y.4    Tokairin, T.5    Ogawa, J.-I.6    Enomoto, K.7
  • 50
    • 0031240077 scopus 로고    scopus 로고
    • High tumor incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32
    • A. Temme, A. Buchmann, H.D. Gabriel, E. Nelles, M. Schwarz, and K. Willecke High tumor incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32 Curr. Biol. 7 1997 713 716
    • (1997) Curr. Biol. , vol.7 , pp. 713-716
    • Temme, A.1    Buchmann, A.2    Gabriel, H.D.3    Nelles, E.4    Schwarz, M.5    Willecke, K.6
  • 51
    • 0043069738 scopus 로고    scopus 로고
    • Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43
    • B.L. Upham, J. Suzuki, G. Chen, Y. Wang, L.R. McCabe, C.C. Chang, V.A. Krutovskikh, H. Yamasaki, and J.E. Trosko Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43 Mol. Carcinog. 37 2003 192 201
    • (2003) Mol. Carcinog. , vol.37 , pp. 192-201
    • Upham, B.L.1    Suzuki, J.2    Chen, G.3    Wang, Y.4    McCabe, L.R.5    Chang, C.C.6    Krutovskikh, V.A.7    Yamasaki, H.8    Trosko, J.E.9
  • 52
    • 27844479110 scopus 로고    scopus 로고
    • Expression of Oct-4 and lack of gap junctional intercellular communication as "hallmarks" for adult human stem cells and cancer cells
    • Orlando, Fl., 27-31 March
    • J.E. Trosko, M.H. Tai, C.C. Chang, L.K. Olson, T.M. Lin, B.V. Madhukar, Expression of Oct-4 and lack of gap junctional intercellular communication as "hallmarks" for adult human stem cells and cancer cells, in: Proceedings of the 95th AACR Meeting, Orlando, Fl., 27-31 March, 2004.
    • (2004) Proceedings of the 95th AACR Meeting
    • Trosko, J.E.1    Tai, M.H.2    Chang, C.C.3    Olson, L.K.4    Lin, T.M.5    Madhukar, B.V.6
  • 53
    • 0035219156 scopus 로고    scopus 로고
    • A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis
    • C.C. Chang, W. Sun, A. Cruz, M. Saitoh, M.H. Tai, and J.E. Trosko A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis Radiat. Res. 155 2001 201 207
    • (2001) Radiat. Res. , vol.155 , pp. 201-207
    • Chang, C.C.1    Sun, W.2    Cruz, A.3    Saitoh, M.4    Tai, M.H.5    Trosko, J.E.6
  • 54
    • 13844280894 scopus 로고    scopus 로고
    • Oct4 expression in adult human stem cells: Evidence in support of the stem cell theory of carcinogenesis
    • M.H. Tai, C.C. Chang, M. Kiupel, J.D. Webster, L.K. Olson, and J.E. Trosko Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis Carcinogenesis 26 2005 495 502
    • (2005) Carcinogenesis , vol.26 , pp. 495-502
    • Tai, M.H.1    Chang, C.C.2    Kiupel, M.3    Webster, J.D.4    Olson, L.K.5    Trosko, J.E.6
  • 55
    • 0034117990 scopus 로고    scopus 로고
    • Paradoxical effects of phenobarbital on mouse hepatocarcinogenesis
    • G.H. Lee Paradoxical effects of phenobarbital on mouse hepatocarcinogenesis Toxicol. Pathol. 28 2000 215 225
    • (2000) Toxicol. Pathol. , vol.28 , pp. 215-225
    • Lee, G.H.1
  • 56
    • 0023183758 scopus 로고
    • Strain and species effects on the inhibition of hepatocyte intercellular communication by liver tumor promoters
    • J.E. Klaunig, and J.R. Ruch Strain and species effects on the inhibition of hepatocyte intercellular communication by liver tumor promoters Cancer Lett. 36 1987 161 168
    • (1987) Cancer Lett. , vol.36 , pp. 161-168
    • Klaunig, J.E.1    Ruch, J.R.2
  • 57
    • 0029974655 scopus 로고    scopus 로고
    • Connection with connexins: The molecular basis of direct intercellular signaling
    • R. Bruzzone, T.W. White, and E.L. Paul Connection with connexins: the molecular basis of direct intercellular signaling Eur. J. Biochem. 238 1996 1 27
    • (1996) Eur. J. Biochem. , vol.238 , pp. 1-27
    • Bruzzone, R.1    White, T.W.2    Paul, E.L.3
  • 58
    • 0027399622 scopus 로고    scopus 로고
    • Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigenesis by lovastatin
    • R.J. Ruch, B.V. Madhukar, J.E. Trosko, and J.E. Klaunig Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigenesis by lovastatin Mol. Carcinog. 7 1996 50 59
    • (1996) Mol. Carcinog. , vol.7 , pp. 50-59
    • Ruch, R.J.1    Madhukar, B.V.2    Trosko, J.E.3    Klaunig, J.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.