Modular polyketide synthases: Investigating intermodular communication using 6 deoxyerythronolide B synthase module 2

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 1, 2006, Pages 213-216

  Moffet, David A ^a,c   Khosla, Chaitan ^b   Cane, David E ^a  

^a BROWN UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

^c LOYOLA MARYMOUNT UNIVERSITY   (United States)

Author keywords

Biosynthesis; Molecular recognition; Polyketides

Indexed keywords

6 DEOXYERYTHRONOLIDE B SYNTHASE; MUTANT PROTEIN; POLYKETIDE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME SPECIFICITY; INCUBATION TIME; PROTEIN PROTEIN INTERACTION;

CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LACTONES; MODELS, CHEMICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; POLYKETIDE SYNTHASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

EID: 27744582590     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.09.017     Document Type: Article

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