-
1
-
-
0024361278
-
Disomic homozygosity in 21-trisomic cells: A mechanism responsible for transient myeloproliferative syndrome
-
Abe K. Kajii T. Niikawa N. ( 1989) Disomic homozygosity in 21-trisomic cells: a mechanism responsible for transient myeloproliferative syndrome. Human Genetics, 82, 313 316.
-
(1989)
Human Genetics
, vol.82
, pp. 313-316
-
-
Abe, K.1
Kajii, T.2
Niikawa, N.3
-
2
-
-
12144287045
-
Natural history of GATA-1 mutations in Down syndrome
-
Ahmed M. Sterberg A. Hall G. Thomas A. Smith O. O'Marcaigh A. Wynn R. Stevens R. Addison M. King D. Stewart B. Gibson B. Roberts I. Vyas P. ( 2004) Natural history of GATA-1 mutations in Down syndrome. Blood, 105, 2480 2486.
-
(2004)
Blood
, vol.105
, pp. 2480-2486
-
-
Ahmed, M.1
Sterberg, A.2
Hall, G.3
Thomas, A.4
Smith, O.5
O'Marcaigh, A.6
Wynn, R.7
Stevens, R.8
Addison, M.9
King, D.10
Stewart, B.11
Gibson, B.12
Roberts, I.13
Vyas, P.14
-
4
-
-
0345291171
-
Reduced folate carrier expression in acute lymphoblastic leukemia: A mechanism for ploidy but not lineage differences in methotrexate accumulation
-
Belkov V.M. Krynetski E.Y. Schuetz J.D. Yanishevski Y. Masson E. Mathew S. Raimondi S. Pui C.H. Relling M.V. Evans W.E. ( 1999) Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation. Blood, 93, 1643 1650.
-
(1999)
Blood
, vol.93
, pp. 1643-1650
-
-
Belkov, V.M.1
Krynetski, E.Y.2
Schuetz, J.D.3
Yanishevski, Y.4
Masson, E.5
Mathew, S.6
Raimondi, S.7
Pui, C.H.8
Relling, M.V.9
Evans, W.E.10
-
6
-
-
0029838764
-
Myelodysplasia and acute myelogenous leukemia in Down's syndrome. a report of 40 children of the AML-BFM Study Group
-
Creutzig U. Ritter J. Vormoor J. Ludwig W.D. Niemeyer C. Reinisch I. Stollmann-Gibbels B. Zimmermann M. Harbott J. ( 1996) Myelodysplasia and acute myelogenous leukemia in Down's syndrome. A report of 40 children of the AML-BFM Study Group. Leukemia, 10, 1677 1686.
-
(1996)
Leukemia
, vol.10
, pp. 1677-1686
-
-
Creutzig, U.1
Ritter, J.2
Vormoor, J.3
Ludwig, W.D.4
Niemeyer, C.5
Reinisch, I.6
Stollmann-Gibbels, B.7
Zimmermann, M.8
Harbott, J.9
-
7
-
-
16544385748
-
Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukaemia: Analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98
-
Creutzig U. Zimmermann M. Reinhardt D. Dworzak M. Stary J. Lehrnbecher T. ( 2004) Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukaemia: analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98. Journal of Clinical Oncology, 22, 4384 4393.
-
(2004)
Journal of Clinical Oncology
, vol.22
, pp. 4384-4393
-
-
Creutzig, U.1
Zimmermann, M.2
Reinhardt, D.3
Dworzak, M.4
Stary, J.5
Lehrnbecher, T.6
-
8
-
-
18944404989
-
AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity
-
2005 May 26 (epub ahead of print). doi 10.1038/sj.leu.2403814-44
-
Creutzig U. Reinhardt D. Diekamp S. Dworzak M. Stary J. Zimmermann M. ( 2005) AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity. Leukemia, 2005 May 26 (epub ahead of print). doi 10.1038/sj.leu.2403814 44.
-
(2005)
Leukemia
-
-
Creutzig, U.1
Reinhardt, D.2
Diekamp, S.3
Dworzak, M.4
Stary, J.5
Zimmermann, M.6
-
9
-
-
0142089730
-
Increased age at diagnosis has a significantly negative effect on outcome in children with Down syndrome and acute myeloid leukemia: A report from the Children's Cancer Group Study 2891
-
Gamis A.S. Woods W.G. Alonzo T.A. Buxton A. Lange B. Barnard D.R. Gold S. Smith F.O. ( 2003) Increased age at diagnosis has a significantly negative effect on outcome in children with Down syndrome and acute myeloid leukemia: a report from the Children's Cancer Group Study 2891. Journal of Clinical Oncology, 21, 3415 3422.
-
(2003)
Journal of Clinical Oncology
, vol.21
, pp. 3415-3422
-
-
Gamis, A.S.1
Woods, W.G.2
Alonzo, T.A.3
Buxton, A.4
Lange, B.5
Barnard, D.R.6
Gold, S.7
Smith, F.O.8
-
10
-
-
0942287758
-
Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome
-
Gurbuxani S. Vyas P. Crispino J.D. ( 2004) Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. Blood, 103, 399 406.
-
(2004)
Blood
, vol.103
, pp. 399-406
-
-
Gurbuxani, S.1
Vyas, P.2
Crispino, J.D.3
-
11
-
-
0342905433
-
Risks of leukaemia and solid tumours in individuals with Down's syndrome
-
Hasle H. Clemmensen I.H. Mikkelsen M. ( 2000) Risks of leukaemia and solid tumours in individuals with Down's syndrome. Lancet, 355, 165 169.
-
(2000)
Lancet
, vol.355
, pp. 165-169
-
-
Hasle, H.1
Clemmensen, I.H.2
Mikkelsen, M.3
-
12
-
-
0037325661
-
A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases
-
Hasle H. Niemeyer C.M. Chessells J.M. Baumann I. Bennett J.M. Kerndrup G. Head D.R. ( 2003) A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases. Leukemia, 17, 277 282.
-
(2003)
Leukemia
, vol.17
, pp. 277-282
-
-
Hasle, H.1
Niemeyer, C.M.2
Chessells, J.M.3
Baumann, I.4
Bennett, J.M.5
Kerndrup, G.6
Head, D.R.7
-
13
-
-
0035726555
-
High expression of platelet-derived growth factor and transforming growth factor-beta 1 in blast cells from patients with Down Syndrome suffering from transient myeloproliferative disorder and organ fibrosis
-
Hattori H. Matsuzaki A. Suminoe A. Ihara K. Nakayama H. Hara T. ( 2001) High expression of platelet-derived growth factor and transforming growth factor-beta 1 in blast cells from patients with Down Syndrome suffering from transient myeloproliferative disorder and organ fibrosis. British Journal of Haematology, 115, 472 475.
-
(2001)
British Journal of Haematology
, vol.115
, pp. 472-475
-
-
Hattori, H.1
Matsuzaki, A.2
Suminoe, A.3
Ihara, K.4
Nakayama, H.5
Hara, T.6
-
14
-
-
0001441065
-
Serial cytogenetic and hematologic studies on a Mongol with trisomy-21 and acute congenital leukemia
-
Honda F. Punnett H.H. Charney E. Miller G. Thiede H.A. ( 1964) Serial cytogenetic and hematologic studies on a Mongol with trisomy-21 and acute congenital leukemia. Journal of Pediatrics, 65, 880 887.
-
(1964)
Journal of Pediatrics
, vol.65
, pp. 880-887
-
-
Honda, F.1
Punnett, H.H.2
Charney, E.3
Miller, G.4
Thiede, H.A.5
-
15
-
-
0030932694
-
Chromosome 21 and platelets: A gene dosage effect
-
Huret J.L. Leonard C. ( 1997) Chromosome 21 and platelets: a gene dosage effect Clinical Genetics, 51, 140 141.
-
(1997)
Clinical Genetics
, vol.51
, pp. 140-141
-
-
Huret, J.L.1
Leonard, C.2
-
16
-
-
0025201044
-
Down's syndrome and acute leukemia in children: An analysis of phenotype by use of monoclonal antibodies and electron microscopic platelet peroxidase reaction
-
Kojima S. Matsuyama T. Sato T. Horibe K. Konishi S. Tsuchida M. Hayashi Y. Kigasawa H. Akiyama Y. Okamura J. Nakahata T. Bessho E. Eguchi M. Nakazawa S. Ueda R. ( 1990) Down's syndrome and acute leukemia in children: an analysis of phenotype by use of monoclonal antibodies and electron microscopic platelet peroxidase reaction. Blood, 76, 2348 2353.
-
(1990)
Blood
, vol.76
, pp. 2348-2353
-
-
Kojima, S.1
Matsuyama, T.2
Sato, T.3
Horibe, K.4
Konishi, S.5
Tsuchida, M.6
Hayashi, Y.7
Kigasawa, H.8
Akiyama, Y.9
Okamura, J.10
Nakahata, T.11
Bessho, E.12
Eguchi, M.13
Nakazawa, S.14
Ueda, R.15
-
17
-
-
0027258566
-
Favourable treatment outcome in children with acute myeloid leukemia and Down syndrome
-
Kojima S. Kato K. Matsuyama T. Yoshikawa T. Horibe K. ( 1993) Favourable treatment outcome in children with acute myeloid leukemia and Down syndrome. Blood, 81, 3164 3165.
-
(1993)
Blood
, vol.81
, pp. 3164-3165
-
-
Kojima, S.1
Kato, K.2
Matsuyama, T.3
Yoshikawa, T.4
Horibe, K.5
-
18
-
-
0030743029
-
Additional chromosome abnormalities in transient abnormal myelopoiesis in Down's syndrome patients
-
Kounami S. Aoyagi N. Tsuno H. Suzuki H. Kitano N. Koike M. ( 1997) Additional chromosome abnormalities in transient abnormal myelopoiesis in Down's syndrome patients. Acta Haematologica, 98, 109 112.
-
(1997)
Acta Haematologica
, vol.98
, pp. 109-112
-
-
Kounami, S.1
Aoyagi, N.2
Tsuno, H.3
Suzuki, H.4
Kitano, N.5
Koike, M.6
-
19
-
-
0000638625
-
Simultaneous occurrence of mongolism and leukemia; Report of a nationwide survey
-
Krivit W. Good R.A. ( 1957) Simultaneous occurrence of mongolism and leukemia; report of a nationwide survey. American Journal of Disease in Childhood, 94, 289 293.
-
(1957)
American Journal of Disease in Childhood
, vol.94
, pp. 289-293
-
-
Krivit, W.1
Good, R.A.2
-
20
-
-
16744366910
-
Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891
-
Lange B.J. Kobrinsky N. Barnard D.R. Arthur D.C. Buckley J.D. Howells W.B. Gold S. Sanders J. Neudorf S. Smith F.O. Woods W.G. ( 1998) Distinctive demography, biology, and outcome of acute myeloid leukemia and myelodysplastic syndrome in children with Down syndrome: Children's Cancer Group Studies 2861 and 2891. Blood, 91, 608 615.
-
(1998)
Blood
, vol.91
, pp. 608-615
-
-
Lange, B.J.1
Kobrinsky, N.2
Barnard, D.R.3
Arthur, D.C.4
Buckley, J.D.5
Howells, W.B.6
Gold, S.7
Sanders, J.8
Neudorf, S.9
Smith, F.O.10
Woods, W.G.11
-
22
-
-
0030035997
-
A population-based study of 272 children with acute myeloid leukaemia treated on two consecutive protocols with different intensity: Best outcome in girls, infants, and children with Down's syndrome. Nordic Society of Paediatric Haematology and Oncology (NOPHO)
-
Lie S.O. Jonmundsson G. Mellander L. Siimes M.A. Yssing M. Gustafsson G. ( 1996) A population-based study of 272 children with acute myeloid leukaemia treated on two consecutive protocols with different intensity: best outcome in girls, infants, and children with Down's syndrome. Nordic Society of Paediatric Haematology and Oncology (NOPHO). British Journal of Haematology, 94, 82 88.
-
(1996)
British Journal of Haematology
, vol.94
, pp. 82-88
-
-
Lie, S.O.1
Jonmundsson, G.2
Mellander, L.3
Siimes, M.A.4
Yssing, M.5
Gustafsson, G.6
-
23
-
-
0026808789
-
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: Experience on Pediatric Oncology Group AML Study 8498
-
Ravindranath Y. Abella E. Krischer J.P. Wiley J. Inoue S. Harris M. Chauvenet A. Alvarado C.S. Dubowy R. Ritchey A.K. Land V. Steuber C.P. Weinstein H. ( 1992) Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498. Blood, 80, 2210 2214.
-
(1992)
Blood
, vol.80
, pp. 2210-2214
-
-
Ravindranath, Y.1
Abella, E.2
Krischer, J.P.3
Wiley, J.4
Inoue, S.5
Harris, M.6
Chauvenet, A.7
Alvarado, C.S.8
Dubowy, R.9
Ritchey, A.K.10
Land, V.11
Steuber, C.P.12
Weinstein, H.13
-
25
-
-
0029820354
-
Bone marrow transplantation for the treatment of haematological disorders in Down's syndrome: Toxicity and outcome
-
Rubin C.M. Mick R. Johnson F.L. ( 1996) Bone marrow transplantation for the treatment of haematological disorders in Down's syndrome: toxicity and outcome. Bone Marrow Transplantation, 18, 533 540.
-
(1996)
Bone Marrow Transplantation
, vol.18
, pp. 533-540
-
-
Rubin, C.M.1
Mick, R.2
Johnson, F.L.3
-
26
-
-
0032830638
-
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
-
Song W.J. Sullivan M.G. Legare R.D. Hutchings S. Tan X. Kufrin D. Ratajczak J. Resende I.C. Haworth C. Hock R. Loh M. Felix C. Roy D.C. Busque L. Kurnit D. Willman C. Gewirtz A.M. Speck N.A. Bushweller J.H. Li F.P. Gardiner K. Poncz M. Maris J.M. Gilliland D.G. ( 1999) Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Naure Genetics, 23, 166 175.
-
(1999)
Naure Genetics
, vol.23
, pp. 166-175
-
-
Song, W.J.1
Sullivan, M.G.2
Legare, R.D.3
Hutchings, S.4
Tan, X.5
Kufrin, D.6
Ratajczak, J.7
Resende, I.C.8
Haworth, C.9
Hock, R.10
Loh, M.11
Felix, C.12
Roy, D.C.13
Busque, L.14
Kurnit, D.15
Willman, C.16
Gewirtz, A.M.17
Speck, N.A.18
Bushweller, J.H.19
Li, F.P.20
Gardiner, K.21
Poncz, M.22
Maris, J.M.23
Gilliland, D.G.24
more..
-
27
-
-
10044264623
-
Down syndrome, drug metabolism and chromosome 21
-
Taub J.W. Ge Y. ( 2005) Down syndrome, drug metabolism and chromosome 21. Pediatric Blood and Cancer, 44, 33 39.
-
(2005)
Pediatric Blood and Cancer
, vol.44
, pp. 33-39
-
-
Taub, J.W.1
Ge, Y.2
-
28
-
-
0029939156
-
Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: A contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia
-
Taub J.W. Matherly L.H. Stout M.L. Buck S.A. Gurney J.G. Ravindranath Y. ( 1996) Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia. Blood, 87, 3395 3403.
-
(1996)
Blood
, vol.87
, pp. 3395-3403
-
-
Taub, J.W.1
Matherly, L.H.2
Stout, M.L.3
Buck, S.A.4
Gurney, J.G.5
Ravindranath, Y.6
-
29
-
-
0033566994
-
Expression of chromosome 21-localized genes in acute myeloid leukemia: Differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin
-
Taub J.W. Huang X. Matherly L.H. Stout M.L. Buck S.A. Massey G.V. Becton D.L. Chang M.N. Weinstein H.J. Ravindranath Y. ( 1999) Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin. Blood, 94, 1393 1400.
-
(1999)
Blood
, vol.94
, pp. 1393-1400
-
-
Taub, J.W.1
Huang, X.2
Matherly, L.H.3
Stout, M.L.4
Buck, S.A.5
Massey, G.V.6
Becton, D.L.7
Chang, M.N.8
Weinstein, H.J.9
Ravindranath, Y.10
-
30
-
-
0030031345
-
Erythroblastic and/or megakaryoblastic leukemia in Down syndrome: Treatment with low dose arabinosyl cytosine
-
Tschernia G. Lejeune F. Bocacara J.F. Denavit M.F. Dommergues J.P. Bernaudin F. ( 1996) Erythroblastic and/or megakaryoblastic leukemia in Down syndrome: treatment with low dose arabinosyl cytosine. Journal of Pediatric Hematology and Oncology, 18, 59 62.
-
(1996)
Journal of Pediatric Hematology and Oncology
, vol.18
, pp. 59-62
-
-
Tschernia, G.1
Lejeune, F.2
Bocacara, J.F.3
Denavit, M.F.4
Dommergues, J.P.5
Bernaudin, F.6
-
31
-
-
0035885943
-
Relationships between age at diagnosis, clinical features, and outcome of therapy in children treated in the Medical Research Council AML 10 and 12 trials for acute myeloid leukemia
-
Webb D.K. Harrison G. Stevens R.F. Gibson B.G. Hann I.M. Wheatley K. ( 2001) Relationships between age at diagnosis, clinical features, and outcome of therapy in children treated in the Medical Research Council AML 10 and 12 trials for acute myeloid leukemia. Blood, 98, 1714 1720.
-
(2001)
Blood
, vol.98
, pp. 1714-1720
-
-
Webb, D.K.1
Harrison, G.2
Stevens, R.F.3
Gibson, B.G.4
Hann, I.M.5
Wheatley, K.6
-
32
-
-
0036727413
-
Acquired mutations in GATA 1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J. Greene M. McDevitt M. Anastasi J. Karp J.E. LeBeau M.M. Crispino J.D. ( 2002). Acquired mutations in GATA 1 in the megakaryoblastic leukemia of Down syndrome. Nature Genetics, 32, 148 152.
-
(2002)
Nature Genetics
, vol.32
, pp. 148-152
-
-
Wechsler, J.1
Greene, M.2
McDevitt, M.3
Anastasi, J.4
Karp, J.E.5
Lebeau, M.M.6
Crispino, J.D.7
-
33
-
-
20144388603
-
Acute leukaemia in children with Down syndrome: A population-based Nordic study
-
Zeller B. Gustafsson G. Forestier E. Abrahamsson J. Clausen N. Heldrup J. Hovi L. Jonmundsson G. Lie S.O. Glomstein A. Hasle H. ( 2005) Acute leukaemia in children with Down syndrome: a population-based Nordic study. British Journal of Haematology, 128, 797 804.
-
(2005)
British Journal of Haematology
, vol.128
, pp. 797-804
-
-
Zeller, B.1
Gustafsson, G.2
Forestier, E.3
Abrahamsson, J.4
Clausen, N.5
Heldrup, J.6
Hovi, L.7
Jonmundsson, G.8
Lie, S.O.9
Glomstein, A.10
Hasle, H.11
-
34
-
-
0030076607
-
The treatment of children with acute megakaryoblastic leukemia who have Down's syndrome
-
Zipursky A. ( 1996) The treatment of children with acute megakaryoblastic leukemia who have Down's syndrome. Journal of Pediatric Hematology and Oncology, 18, 10 12.
-
(1996)
Journal of Pediatric Hematology and Oncology
, vol.18
, pp. 10-12
-
-
Zipursky, A.1
-
39
-
-
0032941980
-
Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome
-
Zipursky A. Brown E.J. Christensen H. Doyle J. ( 1999) Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome. Clinical and Laboratory Medicine, 19, 157 167.
-
(1999)
Clinical and Laboratory Medicine
, vol.19
, pp. 157-167
-
-
Zipursky, A.1
Brown, E.J.2
Christensen, H.3
Doyle, J.4
-
40
-
-
0032078283
-
Acute myelogenous leukemia in Down's syndrome: Report of a single pediatric institution using a BFM treatment strategy
-
Zubizarreta P. Felice M.S. Alfaro E. Fraquelli L. Casak S. Quinteros R. Cygler A. Gallego M. Perez L.E. Sackmann-Muriel F. ( 1998) Acute myelogenous leukemia in Down's syndrome: report of a single pediatric institution using a BFM treatment strategy. Leukemia Research, 22, 465 472.
-
(1998)
Leukemia Research
, vol.22
, pp. 465-472
-
-
Zubizarreta, P.1
Felice, M.S.2
Alfaro, E.3
Fraquelli, L.4
Casak, S.5
Quinteros, R.6
Cygler, A.7
Gallego, M.8
Perez, L.E.9
Sackmann-Muriel, F.10
-
41
-
-
0036098159
-
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome
-
Zwaan C.M. Kaspers G.J. Pieters R. Hahlen K. Janka-Schaub G.E. van Zantwijk C.H. Huismans D.R. de Vries E. Rots M.G. Peters G.J. Jansen G. Creutzig U. Veerman A.J. ( 2002) Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome. Blood, 99, 245 251.
-
(2002)
Blood
, vol.99
, pp. 245-251
-
-
Zwaan, C.M.1
Kaspers, G.J.2
Pieters, R.3
Hahlen, K.4
Janka-Schaub, G.E.5
Van Zantwijk, C.H.6
Huismans, D.R.7
De Vries, E.8
Rots, M.G.9
Peters, G.J.10
Jansen, G.11
Creutzig, U.12
Veerman, A.J.13
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