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Volumn 50, Issue 1, 2005, Pages 156-168

Pathophysiological basis of drug-induced dyskinesias in Parkinson's disease

Author keywords

Basal ganglia; Dyskinesia; Levodopa; MPTP; Parkinson's disease

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; AMANTADINE; BROMOCRIPTINE; DEXTROMETHORPHAN; DOPAMINE RECEPTOR; ETIRACETAM; LEVODOPA; MIRTAZAPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPEPTIDE; PRAMIPEXOLE; RISPERIDONE; RITANSERIN; ROPINIROLE; SELEGILINE; TERGURIDE; TRANSCRIPTION FACTOR FRA 1; TRANSCRIPTION FACTOR FRA 2;

EID: 27744564201     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresrev.2005.05.005     Document Type: Review
Times cited : (20)

References (149)
  • 1
    • 0027494446 scopus 로고
    • Changes in brain dopamine receptors in MPTP parkinsonian monkeys following l-dopa treatment
    • G.M. Alexander, R.J. Schwartzman, J.R. Grothusen, L. Brainard, and S.W. Gordon Changes in brain dopamine receptors in MPTP parkinsonian monkeys following l-dopa treatment Brain Res. 625 1993 276 282
    • (1993) Brain Res. , vol.625 , pp. 276-282
    • Alexander, G.M.1    Schwartzman, R.J.2    Grothusen, J.R.3    Brainard, L.4    Gordon, S.W.5
  • 2
    • 0033428178 scopus 로고    scopus 로고
    • Striatal fosB expression is causally linked with l-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease
    • M. Andersson, A. Hilbertson, and M.A. Cenci Striatal fosB expression is causally linked with l-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease Neurobiol. Dis. 6 1999 461 474
    • (1999) Neurobiol. Dis. , vol.6 , pp. 461-474
    • Andersson, M.1    Hilbertson, A.2    Cenci, M.A.3
  • 5
    • 0034028679 scopus 로고    scopus 로고
    • Treatment of advanced Parkinson's disease by unilateral posterior GPi pallidotomy: 4-year results of a pilot study
    • M.S. Baron, J.L. Vitek, R.A. Bakay, J. Green, W.M. McDonald, S.A. Cole, and M.R. DeLong Treatment of advanced Parkinson's disease by unilateral posterior GPi pallidotomy: 4-year results of a pilot study Mov. Disord. 15 2000 230 237
    • (2000) Mov. Disord. , vol.15 , pp. 230-237
    • Baron, M.S.1    Vitek, J.L.2    Bakay, R.A.3    Green, J.4    McDonald, W.M.5    Cole, S.A.6    Delong, M.R.7
  • 7
    • 0022492455 scopus 로고
    • Chronic treatment with l-DOPA, but not bromocriptine induces dyskinesia in MPTP-parkinsonian monkeys. Correlation with [3H]spiperone binding
    • P.J. Bedard, T. Di Paolo, P. Falardeau, and R. Boucher Chronic treatment with l-DOPA, but not bromocriptine induces dyskinesia in MPTP-parkinsonian monkeys. Correlation with [3H]spiperone binding Brain Res. 379 1986 294 299
    • (1986) Brain Res. , vol.379 , pp. 294-299
    • Bedard, P.J.1    Di Paolo, T.2    Falardeau, P.3    Boucher, R.4
  • 10
    • 0034799117 scopus 로고    scopus 로고
    • Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson's disease. Extension to new indications such as dystonia and epilepsy
    • A.L. Benabid, A. Koudsie, A. Benazzouz, L. Vercueil, V. Fraix, S. Chabardes, J.F. Lebas, and P. Pollak Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson's disease. Extension to new indications such as dystonia and epilepsy J. Neurol. 248 Suppl. 3 2001 III37 III47
    • (2001) J. Neurol. , vol.248 , Issue.3 SUPPL.
    • Benabid, A.L.1    Koudsie, A.2    Benazzouz, A.3    Vercueil, L.4    Fraix, V.5    Chabardes, S.6    Lebas, J.F.7    Pollak, P.8
  • 11
    • 0025169590 scopus 로고
    • Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
    • H. Bergman, T. Wichmann, and M.R. DeLong Reversal of experimental parkinsonism by lesions of the subthalamic nucleus Science 249 1990 1436 1438
    • (1990) Science , vol.249 , pp. 1436-1438
    • Bergman, H.1    Wichmann, T.2    Delong, M.R.3
  • 12
    • 0035961219 scopus 로고    scopus 로고
    • Pallidal border cells: An anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey
    • E. Bezard, T. Boraud, S. Chalon, J.M. Brotchie, D. Guilloteau, and C.E. Gross Pallidal border cells: an anatomical and electrophysiological study in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey Neuroscience 103 2001 117 123
    • (2001) Neuroscience , vol.103 , pp. 117-123
    • Bezard, E.1    Boraud, T.2    Chalon, S.3    Brotchie, J.M.4    Guilloteau, D.5    Gross, C.E.6
  • 13
    • 0030908103 scopus 로고    scopus 로고
    • Modulation of levodopa-induced motor response complications by NMDA antagonists in Parkinson's disease
    • P.J. Blanchet, S.M. Papa, L.V. Metman, M.M. Mouradian, and T.N. Chase Modulation of levodopa-induced motor response complications by NMDA antagonists in Parkinson's disease Neurosci. Biobehav. Rev. 21 1997 447 453
    • (1997) Neurosci. Biobehav. Rev. , vol.21 , pp. 447-453
    • Blanchet, P.J.1    Papa, S.M.2    Metman, L.V.3    Mouradian, M.M.4    Chase, T.N.5
  • 14
    • 0031689728 scopus 로고    scopus 로고
    • Amantadine reduces levodopa-induced dyskinesias in parkinsonian monkeys
    • P.J. Blanchet, S. Konitsiotis, and T.N. Chase Amantadine reduces levodopa-induced dyskinesias in parkinsonian monkeys Mov. Disord. 13 1998 798 802
    • (1998) Mov. Disord. , vol.13 , pp. 798-802
    • Blanchet, P.J.1    Konitsiotis, S.2    Chase, T.N.3
  • 15
    • 0032797570 scopus 로고    scopus 로고
    • Differing effects of N-methyl-d-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl- tetrahydropyridine monkeys
    • P.J. Blanchet, S. Konitsiotis, E.R. Whittemore, Z.L. Zhou, R.M. Woodward, and T.N. Chase Differing effects of N-methyl-d-aspartate receptor subtype selective antagonists on dyskinesias in levodopa-treated 1-methyl-4-phenyl- tetrahydropyridine monkeys J. Pharmacol. Exp. Ther. 290 1999 1034 1040
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 1034-1040
    • Blanchet, P.J.1    Konitsiotis, S.2    Whittemore, E.R.3    Zhou, Z.L.4    Woodward, R.M.5    Chase, T.N.6
  • 16
    • 0037208549 scopus 로고    scopus 로고
    • Renaissance of amantadine in the treatment of Parkinson's disease
    • P.J. Blanchet, L.V. Metman, and T.N. Chase Renaissance of amantadine in the treatment of Parkinson's disease Adv. Neurol. 91 2003 251 257
    • (2003) Adv. Neurol. , vol.91 , pp. 251-257
    • Blanchet, P.J.1    Metman, L.V.2    Chase, T.N.3
  • 18
    • 8044229410 scopus 로고    scopus 로고
    • Comparison of immediate-release and controlled release carbidopa/levodopa in Parkinson's disease. a multicenter 5-year study. the CR First Study Group
    • G. Block, C. Liss, S. Reines, J. Irr, and D. Nibbelink Comparison of immediate-release and controlled release carbidopa/levodopa in Parkinson's disease. A multicenter 5-year study. The CR First Study Group Eur. Neurol. 37 1997 23 27
    • (1997) Eur. Neurol. , vol.37 , pp. 23-27
    • Block, G.1    Liss, C.2    Reines, S.3    Irr, J.4    Nibbelink, D.5
  • 19
    • 0032536767 scopus 로고    scopus 로고
    • Effects of l-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey
    • T. Boraud, E. Bezard, D. Guehl, B. Bioulac, and C. Gross Effects of l-DOPA on neuronal activity of the globus pallidus externalis (GPe) and globus pallidus internalis (GPi) in the MPTP-treated monkey Brain Res. 787 1998 157 160
    • (1998) Brain Res. , vol.787 , pp. 157-160
    • Boraud, T.1    Bezard, E.2    Guehl, D.3    Bioulac, B.4    Gross, C.5
  • 21
    • 0036662945 scopus 로고    scopus 로고
    • Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism
    • N. Breysse, C. Baunez, W. Spooren, F. Gasparini, and M. Amalric Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism J. Neurosci. 22 2002 5669 5678
    • (2002) J. Neurosci. , vol.22 , pp. 5669-5678
    • Breysse, N.1    Baunez, C.2    Spooren, W.3    Gasparini, F.4    Amalric, M.5
  • 22
    • 0032736127 scopus 로고    scopus 로고
    • Quantitative assessment of dyskinesias in subhuman primates
    • J.M. Brotchie, and S.H. Fox Quantitative assessment of dyskinesias in subhuman primates Mov. Disord. 14 Suppl. 1 1999 40 47
    • (1999) Mov. Disord. , vol.14 , Issue.1 SUPPL. , pp. 40-47
    • Brotchie, J.M.1    Fox, S.H.2
  • 23
    • 0036767998 scopus 로고    scopus 로고
    • Levodopa response motor complications-GABA receptors and preproenkephalin expression in human brain
    • F. Calon, and T. Di Paolo Levodopa response motor complications-GABA receptors and preproenkephalin expression in human brain Parkinsonism Relat. Disord. 8 2002 449 454
    • (2002) Parkinsonism Relat. Disord. , vol.8 , pp. 449-454
    • Calon, F.1    Di Paolo, T.2
  • 24
    • 0033009422 scopus 로고    scopus 로고
    • Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: Effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content
    • F. Calon, M. Morissette, M. Goulet, R. Grondin, P.J. Blanchet, P.J. Bedard, and T. Di Paolo Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: effects on basal ganglia GABA(A)/benzodiazepine receptor complex and GABA content Neurochem. Int. 35 1999 81 91
    • (1999) Neurochem. Int. , vol.35 , pp. 81-91
    • Calon, F.1    Morissette, M.2    Goulet, M.3    Grondin, R.4    Blanchet, P.J.5    Bedard, P.J.6    Di Paolo, T.7
  • 26
    • 0036159502 scopus 로고    scopus 로고
    • Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias
    • F. Calon, S. Birdi, A.H. Rajput, O. Hornykiewicz, P.J. Bedard, and P.T. Di Increase of preproenkephalin mRNA levels in the putamen of Parkinson disease patients with levodopa-induced dyskinesias J. Neuropathol. Exp. Neurol. 61 2002 186 196
    • (2002) J. Neuropathol. Exp. Neurol. , vol.61 , pp. 186-196
    • Calon, F.1    Birdi, S.2    Rajput, A.H.3    Hornykiewicz, O.4    Bedard, P.J.5    Di, P.T.6
  • 27
    • 0346218258 scopus 로고    scopus 로고
    • Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease
    • F. Calon, A.H. Rajput, O. Hornykiewicz, P.J. Bedard, and T. Di Paolo Levodopa-induced motor complications are associated with alterations of glutamate receptors in Parkinson's disease Neurobiol. Dis. 14 2003 404 416
    • (2003) Neurobiol. Dis. , vol.14 , pp. 404-416
    • Calon, F.1    Rajput, A.H.2    Hornykiewicz, O.3    Bedard, P.J.4    Di Paolo, T.5
  • 28
    • 2442595210 scopus 로고    scopus 로고
    • Increased adenosine A2A receptors in the brain of Parkinson's disease patients with dyskinesias
    • F. Calon, M. Dridi, O. Hornykiewicz, P.J. Bedard, A.H. Rajput, and T. Di Paolo Increased adenosine A2A receptors in the brain of Parkinson's disease patients with dyskinesias Brain 127 2004 1075 1084
    • (2004) Brain , vol.127 , pp. 1075-1084
    • Calon, F.1    Dridi, M.2    Hornykiewicz, O.3    Bedard, P.J.4    Rajput, A.H.5    Di Paolo, T.6
  • 29
    • 0036389371 scopus 로고    scopus 로고
    • Transcription factors involved in the pathogenesis of l-DOPA-induced dyskinesia in a rat model of Parkinson's disease
    • M.A. Cenci Transcription factors involved in the pathogenesis of l-DOPA-induced dyskinesia in a rat model of Parkinson's disease Amino Acids 23 2002 105 109
    • (2002) Amino Acids , vol.23 , pp. 105-109
    • Cenci, M.A.1
  • 30
    • 0031925945 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA
    • M.A. Cenci, C.S. Lee, and A. Bjorklund l-DOPA-induced dyskinesia in the rat is associated with striatal overexpression of prodynorphin- and glutamic acid decarboxylase mRNA Eur. J. Neurosci. 10 1998 2694 2706
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2694-2706
    • Cenci, M.A.1    Lee, C.S.2    Bjorklund, A.3
  • 31
    • 0036637271 scopus 로고    scopus 로고
    • Animal models of neurological deficits: How relevant is the rat?
    • M.A. Cenci, I.Q. Whishaw, and T. Schallert Animal models of neurological deficits: how relevant is the rat? Nat. Rev. Neurosci. 3 2002 574 579
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 574-579
    • Cenci, M.A.1    Whishaw, I.Q.2    Schallert, T.3
  • 32
    • 0015712601 scopus 로고
    • Levodopa-induced dyskinesias. Comparison in Parkinsonism-dementia and amyotrophic lateral sclerosis
    • T.N. Chase, E.M. Holden, and J.A. Brody Levodopa-induced dyskinesias. Comparison in Parkinsonism-dementia and amyotrophic lateral sclerosis Arch. Neurol. 29 1973 328 333
    • (1973) Arch. Neurol. , vol.29 , pp. 328-333
    • Chase, T.N.1    Holden, E.M.2    Brody, J.A.3
  • 34
    • 0027347992 scopus 로고
    • Striatal dopaminoceptive system changes and motor response complications in l-dopa-treated patients with advanced Parkinson's disease
    • T.N. Chase, T.M. Engber, and M.M. Mouradian Striatal dopaminoceptive system changes and motor response complications in l-dopa-treated patients with advanced Parkinson's disease Adv. Neurol. 60 1993 181 185
    • (1993) Adv. Neurol. , vol.60 , pp. 181-185
    • Chase, T.N.1    Engber, T.M.2    Mouradian, M.M.3
  • 35
    • 0027725064 scopus 로고
    • Motor response complications and the function of striatal efferent systems
    • T.N. Chase, M.M. Mouradian, and T.M. Engber Motor response complications and the function of striatal efferent systems Neurology 43 1993 S23 S27
    • (1993) Neurology , vol.43
    • Chase, T.N.1    Mouradian, M.M.2    Engber, T.M.3
  • 37
    • 0042866020 scopus 로고    scopus 로고
    • Parkinson's transplant therapy faces setback
    • E. Check Parkinson's transplant therapy faces setback Nature 424 2003 987
    • (2003) Nature , vol.424 , pp. 987
    • Check, E.1
  • 38
    • 0347719298 scopus 로고    scopus 로고
    • The adenosine A(2A) receptor as an attractive target for Parkinson's disease treatment
    • J.F. Chen The adenosine A(2A) receptor as an attractive target for Parkinson's disease treatment Drug News & Perspect. 16 2003 597 604
    • (2003) Drug News & Perspect. , vol.16 , pp. 597-604
    • Chen, J.F.1
  • 39
    • 0345168894 scopus 로고    scopus 로고
    • Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: Implications for the treatment of dyskinesias in Parkinson's disease
    • J.F. Chen, S. Fredduzzi, E. Bastia, L. Yu, R. Moratalla, E. Ongini, and M.A. Schwarzschild Adenosine A2A receptors in neuroadaptation to repeated dopaminergic stimulation: implications for the treatment of dyskinesias in Parkinson's disease Neurology 61 2003 S74 S81
    • (2003) Neurology , vol.61
    • Chen, J.F.1    Fredduzzi, S.2    Bastia, E.3    Yu, L.4    Moratalla, R.5    Ongini, E.6    Schwarzschild, M.A.7
  • 40
    • 0014673226 scopus 로고
    • Modification of Parkinsonism-Chronic treatment with l-dopa
    • G.C. Cotzias, P.S. Papavasiliou, and R. Gellene Modification of Parkinsonism-Chronic treatment with l-dopa N. Engl. J. Med. 280 1969 337 345
    • (1969) N. Engl. J. Med. , vol.280 , pp. 337-345
    • Cotzias, G.C.1    Papavasiliou, P.S.2    Gellene, R.3
  • 42
    • 0344731304 scopus 로고    scopus 로고
    • Subgroups of parkinsonian patients differentiated by peptidergic immunostaining of caudate nucleus biopsies
    • M.L. De Ceballos, and J.J. Lopez-Lozano Subgroups of parkinsonian patients differentiated by peptidergic immunostaining of caudate nucleus biopsies Peptides 20 1999 249 257
    • (1999) Peptides , vol.20 , pp. 249-257
    • De Ceballos, M.L.1    Lopez-Lozano, J.J.2
  • 43
    • 27744583011 scopus 로고    scopus 로고
    • Effect of l-dopa on neuronal activity of subthalamic nucleus and substantia nigra in hemiparkinsonian monkeys
    • M. Deogaonkar, B. Piallat, and T. Subramanian Effect of l-dopa on neuronal activity of subthalamic nucleus and substantia nigra in hemiparkinsonian monkeys Mov. Disord. 20 2005 S75
    • (2005) Mov. Disord. , vol.20 , pp. 75
    • Deogaonkar, M.1    Piallat, B.2    Subramanian, T.3
  • 44
    • 0142103732 scopus 로고    scopus 로고
    • Off-period dystonia in Parkinson's disease but not generalized dystonia is improved by high-frequency stimulation of the subthalamic nucleus
    • O. Detante, L. Vercueil, P. Krack, S. Chabardes, A.L. Benabid, and P. Pollak Off-period dystonia in Parkinson's disease but not generalized dystonia is improved by high-frequency stimulation of the subthalamic nucleus Adv. Neurol. 94 2004 309 314
    • (2004) Adv. Neurol. , vol.94 , pp. 309-314
    • Detante, O.1    Vercueil, L.2    Krack, P.3    Chabardes, S.4    Benabid, A.L.5    Pollak, P.6
  • 45
    • 0034114557 scopus 로고    scopus 로고
    • Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model
    • D.A. Di Monte, A. McCormack, G. Petzinger, A.M. Janson, M. Quik, and W.J. Langston Relationship among nigrostriatal denervation, parkinsonism, and dyskinesias in the MPTP primate model Mov. Disord. 15 2000 459 466
    • (2000) Mov. Disord. , vol.15 , pp. 459-466
    • Di Monte, D.A.1    McCormack, A.2    Petzinger, G.3    Janson, A.M.4    Quik, M.5    Langston, W.J.6
  • 46
  • 47
    • 0029994850 scopus 로고    scopus 로고
    • Alterations in peptide levels in Parkinson's disease and incidental Lewy body disease
    • A. Fernandez, M.L. de Ceballos, S. Rose, P. Jenner, and C.D. Marsden Alterations in peptide levels in Parkinson's disease and incidental Lewy body disease Brain 119 Pt. 3 1996 823 830
    • (1996) Brain , vol.119 , Issue.3 PART , pp. 823-830
    • Fernandez, A.1    De Ceballos, M.L.2    Rose, S.3    Jenner, P.4    Marsden, C.D.5
  • 48
    • 0025818631 scopus 로고
    • Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism
    • M. Filion, L. Tremblay, and P.J. Bedard Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism Brain Res. 547 1991 152 161
    • (1991) Brain Res. , vol.547 , pp. 152-161
    • Filion, M.1    Tremblay, L.2    Bedard, P.J.3
  • 49
    • 4544255049 scopus 로고    scopus 로고
    • Non-subtype-selective opioid receptor antagonism in treatment of levodopa-induced motor complications in Parkinson's disease
    • S. Fox, M. Silverdale, M. Kellett, R. Davies, M. Steiger, N. Fletcher, A. Crossman, and J. Brotchie Non-subtype-selective opioid receptor antagonism in treatment of levodopa-induced motor complications in Parkinson's disease Mov. Disord. 19 2004 554 560
    • (2004) Mov. Disord. , vol.19 , pp. 554-560
    • Fox, S.1    Silverdale, M.2    Kellett, M.3    Davies, R.4    Steiger, M.5    Fletcher, N.6    Crossman, A.7    Brotchie, J.8
  • 50
    • 0037628004 scopus 로고    scopus 로고
    • Expression of neurotransmitter genes in motor regions of the dyskinetic rat after iminodipropionitrile
    • J.A. Fritschi, T. Lauterburg, and J.M. Burgunder Expression of neurotransmitter genes in motor regions of the dyskinetic rat after iminodipropionitrile Neurosci. Lett. 347 2003 45 48
    • (2003) Neurosci. Lett. , vol.347 , pp. 45-48
    • Fritschi, J.A.1    Lauterburg, T.2    Burgunder, J.M.3
  • 52
    • 1542360582 scopus 로고    scopus 로고
    • Effect of a selective glutamate antagonist on l-dopa-induced dyskinesias in drug-naive parkinsonian monkeys
    • A. Hadj Tahar, L. Gregoire, A. Darre, N. Belanger, L. Meltzer, and P.J. Bedard Effect of a selective glutamate antagonist on l-dopa-induced dyskinesias in drug-naive parkinsonian monkeys Neurobiol. Dis. 15 2004 171 176
    • (2004) Neurobiol. Dis. , vol.15 , pp. 171-176
    • Hadj Tahar, A.1    Gregoire, L.2    Darre, A.3    Belanger, N.4    Meltzer, L.5    Bedard, P.J.6
  • 53
    • 0026498026 scopus 로고
    • Excitotoxic acid lesions of the primate subthalamic nucleus result in transient dyskinesias of the contralateral limbs
    • I. Hamada, and M.R. DeLong Excitotoxic acid lesions of the primate subthalamic nucleus result in transient dyskinesias of the contralateral limbs J. Neurophysiol. 68 1992 1850 1858
    • (1992) J. Neurophysiol. , vol.68 , pp. 1850-1858
    • Hamada, I.1    Delong, M.R.2
  • 54
    • 0029762313 scopus 로고    scopus 로고
    • Potential of opioid antagonists in the treatment of levodopa-induced dyskinesias in Parkinson's disease
    • B. Henry, and J.M. Brotchie Potential of opioid antagonists in the treatment of levodopa-induced dyskinesias in Parkinson's disease Drugs Aging 9 1996 149 158
    • (1996) Drugs Aging , vol.9 , pp. 149-158
    • Henry, B.1    Brotchie, J.M.2
  • 55
    • 1342326299 scopus 로고    scopus 로고
    • Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by l-dopa and ropinirole in the MPTP-lesioned marmoset
    • M.P. Hill, E. Bezard, S.G. McGuire, A.R. Crossman, J.M. Brotchie, A. Michel, R. Grimee, and H. Klitgaard Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by l-dopa and ropinirole in the MPTP-lesioned marmoset Mov. Disord. 18 2003 1301 1305
    • (2003) Mov. Disord. , vol.18 , pp. 1301-1305
    • Hill, M.P.1    Bezard, E.2    McGuire, S.G.3    Crossman, A.R.4    Brotchie, J.M.5    Michel, A.6    Grimee, R.7    Klitgaard, H.8
  • 56
    • 3042637096 scopus 로고    scopus 로고
    • Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease
    • M.P. Hill, P. Ravenscroft, E. Bezard, A.R. Crossman, J.M. Brotchie, A. Michel, R. Grimee, and H. Klitgaard Levetiracetam potentiates the antidyskinetic action of amantadine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's disease J. Pharmacol. Exp. Ther. 310 2004 386 394
    • (2004) J. Pharmacol. Exp. Ther. , vol.310 , pp. 386-394
    • Hill, M.P.1    Ravenscroft, P.2    Bezard, E.3    Crossman, A.R.4    Brotchie, J.M.5    Michel, A.6    Grimee, R.7    Klitgaard, H.8
  • 58
    • 0141649537 scopus 로고    scopus 로고
    • Cabergoline, pramipexole and ropinirole used as monotherapy in early Parkinson's disease: An evidence-based comparison
    • R. Inzelberg, E. Schechtman, and P. Nisipeanu Cabergoline, pramipexole and ropinirole used as monotherapy in early Parkinson's disease: an evidence-based comparison Drugs Aging 20 2003 847 855
    • (2003) Drugs Aging , vol.20 , pp. 847-855
    • Inzelberg, R.1    Schechtman, E.2    Nisipeanu, P.3
  • 59
    • 0347031394 scopus 로고    scopus 로고
    • Parkinson's disease, subthalamic stimulation, and selection of candidates: A pathological study
    • B. Jarraya, A.M. Bonnet, C. Duyckaerts, J.L. Houeto, P. Cornu, J.J. Hauw, and Y. Agid Parkinson's disease, subthalamic stimulation, and selection of candidates: a pathological study Mov. Disord. 18 2003 1517 1520
    • (2003) Mov. Disord. , vol.18 , pp. 1517-1520
    • Jarraya, B.1    Bonnet, A.M.2    Duyckaerts, C.3    Houeto, J.L.4    Cornu, P.5    Hauw, J.J.6    Agid, Y.7
  • 60
    • 0345600914 scopus 로고    scopus 로고
    • A2A antagonists as novel non-dopaminergic therapy for motor dysfunction in PD
    • P. Jenner A2A antagonists as novel non-dopaminergic therapy for motor dysfunction in PD Neurology 61 2003 S32 S38
    • (2003) Neurology , vol.61
    • Jenner, P.1
  • 61
    • 0141856260 scopus 로고    scopus 로고
    • The MPTP-treated primate as a model of motor complications in PD: Primate model of motor complications
    • P. Jenner The MPTP-treated primate as a model of motor complications in PD: primate model of motor complications Neurology 61 2003 S4 S11
    • (2003) Neurology , vol.61
    • Jenner, P.1
  • 63
    • 0034298044 scopus 로고    scopus 로고
    • Deep brain stimulation (DBS) therapy for parkinson's disease
    • Y. Katayama Deep brain stimulation (DBS) therapy for parkinson's disease Nippon Rinsho 58 2000 2078 2083
    • (2000) Nippon Rinsho , vol.58 , pp. 2078-2083
    • Katayama, Y.1
  • 64
    • 0033795877 scopus 로고    scopus 로고
    • Double blinded evaluation of the effects of pallidal and subthalamic nucleus stimulation on daytime activity in advanced Parkinson's disease
    • Y. Katayama, M. Kasai, H. Oshima, C. Fukaya, T. Yamamoto, and T. Mizutani Double blinded evaluation of the effects of pallidal and subthalamic nucleus stimulation on daytime activity in advanced Parkinson's disease Parkinsonism Relat. Disord. 7 2000 35 40
    • (2000) Parkinsonism Relat. Disord. , vol.7 , pp. 35-40
    • Katayama, Y.1    Kasai, M.2    Oshima, H.3    Fukaya, C.4    Yamamoto, T.5    Mizutani, T.6
  • 65
    • 0034860332 scopus 로고    scopus 로고
    • Subthalamic nucleus stimulation for Parkinson disease: Benefits observed in levodopa-intolerant patients
    • Y. Katayama, M. Kasai, H. Oshima, C. Fukaya, T. Yamamoto, K. Ogawa, and T. Mizutani Subthalamic nucleus stimulation for Parkinson disease: benefits observed in levodopa-intolerant patients J. Neurosurg. 95 2001 213 221
    • (2001) J. Neurosurg. , vol.95 , pp. 213-221
    • Katayama, Y.1    Kasai, M.2    Oshima, H.3    Fukaya, C.4    Yamamoto, T.5    Ogawa, K.6    Mizutani, T.7
  • 66
    • 0036387577 scopus 로고    scopus 로고
    • Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism
    • R. Klintenberg, P. Svenningsson, L. Gunne, and P.E. Andren Naloxone reduces levodopa-induced dyskinesias and apomorphine-induced rotations in primate models of parkinsonism J. Neural. Transm. 109 2002 1295 1307
    • (2002) J. Neural. Transm. , vol.109 , pp. 1295-1307
    • Klintenberg, R.1    Svenningsson, P.2    Gunne, L.3    Andren, P.E.4
  • 67
    • 0034090891 scopus 로고    scopus 로고
    • AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys
    • S. Konitsiotis, P.J. Blanchet, L. Verhagen, E. Lamers, and T.N. Chase AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys Neurology 54 2000 1589 1595
    • (2000) Neurology , vol.54 , pp. 1589-1595
    • Konitsiotis, S.1    Blanchet, P.J.2    Verhagen, L.3    Lamers, E.4    Chase, T.N.5
  • 69
    • 0034028006 scopus 로고    scopus 로고
    • Surgery for levodopa-induced dyskinesias
    • A.E. Lang Surgery for levodopa-induced dyskinesias Ann. Neurol. 47 2000 S193 S199 (discussion S199-S202)
    • (2000) Ann. Neurol. , vol.47
    • Lang, A.E.1
  • 72
    • 0017796919 scopus 로고
    • Receptor basis for dopaminergic supersensitivity in Parkinson's disease
    • T. Lee, P. Seeman, A. Rajput, I.J. Farley, and O. Hornykiewicz Receptor basis for dopaminergic supersensitivity in Parkinson's disease Nature 273 1978 59 61
    • (1978) Nature , vol.273 , pp. 59-61
    • Lee, T.1    Seeman, P.2    Rajput, A.3    Farley, I.J.4    Hornykiewicz, O.5
  • 73
    • 0030899734 scopus 로고    scopus 로고
    • The need for levodopa as an end point of Parkinson's disease progression in a clinical trial of selegiline and alpha-tocopherol. Parkinson Study Group
    • P. LeWitt, D. Oakes, and L. Cui The need for levodopa as an end point of Parkinson's disease progression in a clinical trial of selegiline and alpha-tocopherol. Parkinson Study Group Mov. Disord. 12 1997 183 189
    • (1997) Mov. Disord. , vol.12 , pp. 183-189
    • Lewitt, P.1    Oakes, D.2    Cui, L.3
  • 75
    • 0034027547 scopus 로고    scopus 로고
    • Neuronal recordings in Parkinson's disease patients with dyskinesias induced by apomorphine
    • A.M. Lozano, A.E. Lang, R. Levy, W. Hutchison, and J. Dostrovsky Neuronal recordings in Parkinson's disease patients with dyskinesias induced by apomorphine Ann. Neurol. 47 2000 S141 S146
    • (2000) Ann. Neurol. , vol.47
    • Lozano, A.M.1    Lang, A.E.2    Levy, R.3    Hutchison, W.4    Dostrovsky, J.5
  • 76
    • 2342459797 scopus 로고    scopus 로고
    • A model of l-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: Relation to motor and cellular parameters of nigrostriatal function
    • M. Lundblad, B. Picconi, H. Lindgren, and M.A. Cenci A model of l-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function Neurobiol. Dis. 16 2004 110 123
    • (2004) Neurobiol. Dis. , vol.16 , pp. 110-123
    • Lundblad, M.1    Picconi, B.2    Lindgren, H.3    Cenci, M.A.4
  • 78
    • 0028297885 scopus 로고
    • Striatal G-proteins: Effects of unilateral 6-hydroxydopamine lesions
    • E.R. Marcotte, R.M. Sullivan, and R.K. Mishra Striatal G-proteins: effects of unilateral 6-hydroxydopamine lesions Neurosci. Lett. 169 1994 195 198
    • (1994) Neurosci. Lett. , vol.169 , pp. 195-198
    • Marcotte, E.R.1    Sullivan, R.M.2    Mishra, R.K.3
  • 79
    • 0347862712 scopus 로고    scopus 로고
    • Bilateral subthalamic nucleus lesion reverses l-dopa-induced motor fluctuations and facilitates dyskinetic movements in hemiparkinsonian rats
    • C. Marin, A. Jimenez, E. Tolosa, M. Bonastre, and J. Bove Bilateral subthalamic nucleus lesion reverses l-dopa-induced motor fluctuations and facilitates dyskinetic movements in hemiparkinsonian rats Synapse 51 2004 140 150
    • (2004) Synapse , vol.51 , pp. 140-150
    • Marin, C.1    Jimenez, A.2    Tolosa, E.3    Bonastre, M.4    Bove, J.5
  • 81
    • 0001925175 scopus 로고
    • Fluctuations of disability in Parkinson's disease: Clinical aspects
    • C.D. Marsden S. Fahn Butterworth London
    • C.D.P. Marsden, J.D. Quinn, and N. Fluctuations of disability in Parkinson's disease: clinical aspects C.D. Marsden S. Fahn Movement Disorders 1981 Butterworth London 96 122
    • (1981) Movement Disorders , pp. 96-122
    • Marsden, C.D.P.1    Quinn, J.D.2
  • 84
    • 0034030456 scopus 로고    scopus 로고
    • Simultaneous intrastriatal and intranigral grafting (double grafts) in the rat model of Parkinson's disease
    • I. Mendez, K.A. Baker, and M. Hong Simultaneous intrastriatal and intranigral grafting (double grafts) in the rat model of Parkinson's disease Brain Res. Brain Res. Rev. 32 2000 328 339
    • (2000) Brain Res. Brain Res. Rev. , vol.32 , pp. 328-339
    • Mendez, I.1    Baker, K.A.2    Hong, M.3
  • 87
    • 0028630805 scopus 로고
    • A randomised controlled study comparing bromocriptine to which levodopa was later added, with levodopa alone in previously untreated patients with Parkinson's disease: A five year follow up
    • J.L. Montastruc, O. Rascol, J.M. Senard, and A. Rascol A randomised controlled study comparing bromocriptine to which levodopa was later added, with levodopa alone in previously untreated patients with Parkinson's disease: a five year follow up J. Neurol., Neurosurg. Psychiatry 57 1994 1034 1038
    • (1994) J. Neurol., Neurosurg. Psychiatry , vol.57 , pp. 1034-1038
    • Montastruc, J.L.1    Rascol, O.2    Senard, J.M.3    Rascol, A.4
  • 88
    • 0029661854 scopus 로고    scopus 로고
    • Changes of D1 and D2 dopamine receptor mRNA in the brains of monkeys lesioned with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Correction with chronic administration of l-3,4-dihydroxyphenylalanine
    • M. Morissette, M. Goulet, F. Calon, P. Falardeau, P.J. Blanchet, P.J. Bedard, and T. Di Paolo Changes of D1 and D2 dopamine receptor mRNA in the brains of monkeys lesioned with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: correction with chronic administration of l-3,4-dihydroxyphenylalanine Mol. Pharmacol. 50 1996 1073 1079
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1073-1079
    • Morissette, M.1    Goulet, M.2    Calon, F.3    Falardeau, P.4    Blanchet, P.J.5    Bedard, P.J.6    Di Paolo, T.7
  • 89
    • 0036845961 scopus 로고    scopus 로고
    • Response to levodopa in parkinsonian patients with bilateral subthalamic nucleus stimulation
    • E. Moro, R.J. Esselink, A.L. Benabid, and P. Pollak Response to levodopa in parkinsonian patients with bilateral subthalamic nucleus stimulation Brain 125 2002 2408 2417
    • (2002) Brain , vol.125 , pp. 2408-2417
    • Moro, E.1    Esselink, R.J.2    Benabid, A.L.3    Pollak, P.4
  • 90
    • 0023627787 scopus 로고
    • Motor fluctuations in Parkinson's disease: Pathogenetic and therapeutic studies
    • M.M. Mouradian, J.L. Juncos, G. Fabbrini, and T.N. Chase Motor fluctuations in Parkinson's disease: pathogenetic and therapeutic studies Ann. Neurol. 22 1987 475 479
    • (1987) Ann. Neurol. , vol.22 , pp. 475-479
    • Mouradian, M.M.1    Juncos, J.L.2    Fabbrini, G.3    Chase, T.N.4
  • 91
    • 0025129116 scopus 로고
    • Modification of central dopaminergic mechanisms by continuous levodopa therapy for advanced Parkinson's disease
    • M.M. Mouradian, I.J. Heuser, F. Baronti, and T.N. Chase Modification of central dopaminergic mechanisms by continuous levodopa therapy for advanced Parkinson's disease Ann. Neurol. 27 1990 18 23
    • (1990) Ann. Neurol. , vol.27 , pp. 18-23
    • Mouradian, M.M.1    Heuser, I.J.2    Baronti, F.3    Chase, T.N.4
  • 93
    • 4644271500 scopus 로고    scopus 로고
    • Discharge rate of substantia nigra pars reticulata neurons is reduced in non-parkinsonian monkeys with apomorphine-induced orofacial dyskinesia
    • A. Nevet, G. Morris, G. Saban, N. Fainstein, and H. Bergman Discharge rate of substantia nigra pars reticulata neurons is reduced in non-parkinsonian monkeys with apomorphine-induced orofacial dyskinesia J. Neurophysiol. 92 2004 1973 1981
    • (2004) J. Neurophysiol. , vol.92 , pp. 1973-1981
    • Nevet, A.1    Morris, G.2    Saban, G.3    Fainstein, N.4    Bergman, H.5
  • 94
    • 0034027839 scopus 로고    scopus 로고
    • Clinical pharmacology of levodopa-induced dyskinesia
    • J.G. Nutt Clinical pharmacology of levodopa-induced dyskinesia Ann. Neurol. 47 2000 S160 S164 (discussion S164-S166)
    • (2000) Ann. Neurol. , vol.47
    • Nutt, J.G.1
  • 95
    • 0022443805 scopus 로고
    • Levodopa pharmacokinetics and pharmacodynamics in fluctuating parkinsonian patients
    • J.G. Nutt, and W.R. Woodward Levodopa pharmacokinetics and pharmacodynamics in fluctuating parkinsonian patients Neurology 36 1986 739 744
    • (1986) Neurology , vol.36 , pp. 739-744
    • Nutt, J.G.1    Woodward, W.R.2
  • 96
    • 0026480977 scopus 로고
    • Effect of long-term therapy on the pharmacodynamics of levodopa. Relation to on-off phenomenon
    • J.G. Nutt, W.R. Woodward, J.H. Carter, and S.T. Gancher Effect of long-term therapy on the pharmacodynamics of levodopa. Relation to on-off phenomenon Arch. Neurol. 49 1992 1123 1130
    • (1992) Arch. Neurol. , vol.49 , pp. 1123-1130
    • Nutt, J.G.1    Woodward, W.R.2    Carter, J.H.3    Gancher, S.T.4
  • 97
    • 0036264465 scopus 로고    scopus 로고
    • Evolution of the response to levodopa during the first 4 years of therapy
    • J.G. Nutt, J.H. Carter, E.S. Lea, and G.J. Sexton Evolution of the response to levodopa during the first 4 years of therapy Ann. Neurol. 51 2002 686 693
    • (2002) Ann. Neurol. , vol.51 , pp. 686-693
    • Nutt, J.G.1    Carter, J.H.2    Lea, E.S.3    Sexton, G.J.4
  • 98
    • 0042572484 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice
    • M.F. O'Neill, C. Heron-Maxwell, M.W. Conway, J.A. Monn, and P. Ornstein Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice Neuropharmacology 45 2003 565 574
    • (2003) Neuropharmacology , vol.45 , pp. 565-574
    • O'Neill, M.F.1    Heron-Maxwell, C.2    Conway, M.W.3    Monn, J.A.4    Ornstein, P.5
  • 99
    • 0028337689 scopus 로고
    • The role of pulsatile versus continuous dopamine receptor stimulation for functional recovery in Parkinson's disease
    • J.A. Obeso, F. Grandas, M.T. Herrero, and R. Horowski The role of pulsatile versus continuous dopamine receptor stimulation for functional recovery in Parkinson's disease Eur. J. Neurosci. 6 1994 889 897
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 889-897
    • Obeso, J.A.1    Grandas, F.2    Herrero, M.T.3    Horowski, R.4
  • 100
    • 0033695441 scopus 로고    scopus 로고
    • Levodopa motor complications in Parkinson's disease
    • J.A. Obeso, C.W. Olanow, and J.G. Nutt Levodopa motor complications in Parkinson's disease Trends Neurosci. 23 2000 S2 S7
    • (2000) Trends Neurosci. , vol.23
    • Obeso, J.A.1    Olanow, C.W.2    Nutt, J.G.3
  • 101
    • 0034109592 scopus 로고    scopus 로고
    • Pathophysiology of levodopa-induced dyskinesias in Parkinson's disease: Problems with the current model
    • J.A. Obeso, M.C. Rodriguez-Oroz, M. Rodriguez, M.R. DeLong, and C.W. Olanow Pathophysiology of levodopa-induced dyskinesias in Parkinson's disease: problems with the current model Ann. Neurol. 47 2000 S22 S32 (discussion S32-S24)
    • (2000) Ann. Neurol. , vol.47
    • Obeso, J.A.1    Rodriguez-Oroz, M.C.2    Rodriguez, M.3    Delong, M.R.4    Olanow, C.W.5
  • 103
    • 0034557973 scopus 로고    scopus 로고
    • Use of selective thalamotomy for various kinds of movement disorder, based on basic studies
    • C. Ohye Use of selective thalamotomy for various kinds of movement disorder, based on basic studies Stereotact. Funct. Neurosurg. 75 2000 54 65
    • (2000) Stereotact. Funct. Neurosurg. , vol.75 , pp. 54-65
    • Ohye, C.1
  • 105
    • 4043111360 scopus 로고    scopus 로고
    • Overlesioned hemiparkinsonian non human primate model: Correlation between clinical, neurochemical and histochemical changes
    • Y. Oiwa, J.L. Eberling, D. Nagy, P. Pivirotto, M.E. Emborg, and K.S. Bankiewicz Overlesioned hemiparkinsonian non human primate model: correlation between clinical, neurochemical and histochemical changes Front. Biosci. 8 2003 a155 a166
    • (2003) Front. Biosci. , vol.8
    • Oiwa, Y.1    Eberling, J.L.2    Nagy, D.3    Pivirotto, P.4    Emborg, M.E.5    Bankiewicz, K.S.6
  • 106
    • 0031946558 scopus 로고    scopus 로고
    • Current status of selegiline as a neuroprotective agent in Parkinson's disease
    • C.W. Olanow, C. Mytilineou, and W. Tatton Current status of selegiline as a neuroprotective agent in Parkinson's disease Mov. Disord. 1 Suppl. 1 1998 55 58
    • (1998) Mov. Disord. , vol.1 , Issue.1 SUPPL. , pp. 55-58
    • Olanow, C.W.1    Mytilineou, C.2    Tatton, W.3
  • 108
    • 0344738699 scopus 로고    scopus 로고
    • Adenosine A(2A) receptors in nonlocomotor features of Parkinson's disease: Introduction
    • E. Ongini Adenosine A(2A) receptors in nonlocomotor features of Parkinson's disease: introduction Neurology 61 2003 S72 S73
    • (2003) Neurology , vol.61
    • Ongini, E.1
  • 109
    • 0026571476 scopus 로고
    • The use of thalamotomy in the treatment of levodopa-induced dyskinesia
    • R.D. Page The use of thalamotomy in the treatment of levodopa-induced dyskinesia Acta Neurochir. (Wien) 114 1992 77 117
    • (1992) Acta Neurochir. (Wien) , vol.114 , pp. 77-117
    • Page, R.D.1
  • 110
    • 0027286045 scopus 로고
    • Thalamotomy for the alleviation of levodopa-induced dyskinesia: Experimental studies in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkey
    • R.D. Page, M.A. Sambrook, and A.R. Crossman Thalamotomy for the alleviation of levodopa-induced dyskinesia: experimental studies in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkey Neuroscience 55 1993 147 165
    • (1993) Neuroscience , vol.55 , pp. 147-165
    • Page, R.D.1    Sambrook, M.A.2    Crossman, A.R.3
  • 111
    • 0029665122 scopus 로고    scopus 로고
    • Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys
    • S.M. Papa, and T.N. Chase Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys Ann. Neurol. 39 1996 574 578
    • (1996) Ann. Neurol. , vol.39 , pp. 574-578
    • Papa, S.M.1    Chase, T.N.2
  • 112
    • 0029665122 scopus 로고    scopus 로고
    • Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys
    • S.M. Papa, and T.N. Chase Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys Ann. Neurol. 39 1996 574 578 (see comment)
    • (1996) Ann. Neurol. , vol.39 , pp. 574-578
    • Papa, S.M.1    Chase, T.N.2
  • 113
    • 0032722841 scopus 로고    scopus 로고
    • Internal globus pallidus discharge is nearly suppressed during levodopa-induced dyskinesias
    • S.M. Papa, R. Desimone, M. Fiorani, and E.H. Oldfield Internal globus pallidus discharge is nearly suppressed during levodopa-induced dyskinesias Ann. Neurol. 46 1999 732 738
    • (1999) Ann. Neurol. , vol.46 , pp. 732-738
    • Papa, S.M.1    Desimone, R.2    Fiorani, M.3    Oldfield, E.H.4
  • 115
    • 9044226896 scopus 로고    scopus 로고
    • Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa
    • Parkinson Study Group
    • Parkinson Study Group Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa Ann. Neurol. 39 1996 37 45
    • (1996) Ann. Neurol. , vol.39 , pp. 37-45
  • 116
    • 0031893241 scopus 로고    scopus 로고
    • Mortality in DATATOP: A multicenter trial in early Parkinson's disease
    • Parkinson Study Group
    • Parkinson Study Group Mortality in DATATOP: a multicenter trial in early Parkinson's disease Ann. Neurol. 43 1998 318 325
    • (1998) Ann. Neurol. , vol.43 , pp. 318-325
  • 117
    • 0033960907 scopus 로고    scopus 로고
    • A randomized controlled trial comparing pramipexole with levodopa in early Parkinson's disease: Design and methods of the CALM-PD Study
    • Parkinson Study Group
    • Parkinson Study Group A randomized controlled trial comparing pramipexole with levodopa in early Parkinson's disease: design and methods of the CALM-PD Study Clin. Neuropharmacol. 23 2000 34 44
    • (2000) Clin. Neuropharmacol. , vol.23 , pp. 34-44
  • 118
  • 119
    • 0034935182 scopus 로고    scopus 로고
    • L-dopa induces dyskinesia in normal monkeys: Behavioural and pharmacokinetic observations
    • R.K. Pearce, M. Heikkila, I.B. Linden, and P. Jenner l-dopa induces dyskinesia in normal monkeys: behavioural and pharmacokinetic observations Psychopharmacology 156 2001 402 409
    • (2001) Psychopharmacology , vol.156 , pp. 402-409
    • Pearce, R.K.1    Heikkila, M.2    Linden, I.B.3    Jenner, P.4
  • 120
    • 0027354227 scopus 로고
    • Risk factors for motor response complications in l-dopa-treated parkinsonian patients
    • A. Peppe, J.M. Dambrosia, and T.N. Chase Risk factors for motor response complications in l-dopa-treated parkinsonian patients Adv. Neurol. 60 1993 698 702
    • (1993) Adv. Neurol. , vol.60 , pp. 698-702
    • Peppe, A.1    Dambrosia, J.M.2    Chase, T.N.3
  • 121
    • 0041386058 scopus 로고    scopus 로고
    • Dyskinesias after transplantation in Parkinson's disease
    • P. Piccini Dyskinesias after transplantation in Parkinson's disease Lancet Neurol. 1 2002 472
    • (2002) Lancet Neurol. , vol.1 , pp. 472
    • Piccini, P.1
  • 123
    • 0037008416 scopus 로고    scopus 로고
    • Increases in striatal preproenkephalin gene expression are associated with nigrostriatal damage but not l-DOPA-induced dyskinesias in the squirrel monkey
    • M. Quik, S. Police, J.W. Langston, and D.A. Di Monte Increases in striatal preproenkephalin gene expression are associated with nigrostriatal damage but not l-DOPA-induced dyskinesias in the squirrel monkey Neuroscience 113 2002 213 220
    • (2002) Neuroscience , vol.113 , pp. 213-220
    • Quik, M.1    Police, S.2    Langston, J.W.3    Di Monte, D.A.4
  • 125
    • 0034126269 scopus 로고    scopus 로고
    • Medical treatment of levodopa-induced dyskinesias
    • O. Rascol Medical treatment of levodopa-induced dyskinesias Ann. Neurol. 47 2000 S179 S188
    • (2000) Ann. Neurol. , vol.47
    • Rascol, O.1
  • 126
    • 0034050670 scopus 로고    scopus 로고
    • The pharmacological therapeutic management of levodopa-induced dyskinesias in patients with Parkinson's disease
    • O. Rascol The pharmacological therapeutic management of levodopa-induced dyskinesias in patients with Parkinson's disease J. Neurol. 2 2000 II51 II57
    • (2000) J. Neurol. , vol.2
    • Rascol, O.1
  • 128
    • 0034682308 scopus 로고    scopus 로고
    • A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group
    • O. Rascol, D.J. Brooks, A.D. Korczyn, P.P. De Deyn, C.E. Clarke, and A.E. Lang A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group N. Engl. J. Med. 342 2000 1484 1491
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1484-1491
    • Rascol, O.1    Brooks, D.J.2    Korczyn, A.D.3    De Deyn, P.P.4    Clarke, C.E.5    Lang, A.E.6
  • 130
    • 0031985731 scopus 로고    scopus 로고
    • Early treatment of Parkinson's disease with cabergoline delays the onset of motor complications. Results of a double-blind levodopa controlled trial. the PKDS009 Study Group
    • U.K. Rinne, F. Bracco, C. Chouza, E. Dupont, O. Gershanik, J.F. Marti Masso, J.L. Montastruc, and C.D. Marsden Early treatment of Parkinson's disease with cabergoline delays the onset of motor complications. Results of a double-blind levodopa controlled trial. The PKDS009 Study Group Drugs 55 Suppl. 1 1998 23 30
    • (1998) Drugs , vol.55 , Issue.1 SUPPL. , pp. 23-30
    • Rinne, U.K.1    Bracco, F.2    Chouza, C.3    Dupont, E.4    Gershanik, O.5    Marti Masso, J.F.6    Montastruc, J.L.7    Marsden, C.D.8
  • 131
    • 0016421061 scopus 로고
    • Drug-induced dyskinesia in monkeys
    • J.F. Sassin Drug-induced dyskinesia in monkeys Adv. Neurol. 10 1975 47 54
    • (1975) Adv. Neurol. , vol.10 , pp. 47-54
    • Sassin, J.F.1
  • 132
    • 0031711714 scopus 로고    scopus 로고
    • DATATOP: A decade of neuroprotective inquiry. Parkinson Study Group. Deprenyl and tocopherol antioxidative therapy of parkinsonism
    • I. Shoulson DATATOP: a decade of neuroprotective inquiry. Parkinson Study Group. Deprenyl and tocopherol antioxidative therapy of parkinsonism Ann. Neurol. 44 1998 S160 S166
    • (1998) Ann. Neurol. , vol.44
    • Shoulson, I.1
  • 133
    • 0036118681 scopus 로고    scopus 로고
    • Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia
    • M.A. Silverdale, A.R. Crossman, and J.M. Brotchie Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia Exp. Neurol. 174 2002 21 28
    • (2002) Exp. Neurol. , vol.174 , pp. 21-28
    • Silverdale, M.A.1    Crossman, A.R.2    Brotchie, J.M.3
  • 135
    • 0037809608 scopus 로고    scopus 로고
    • Treatment of advanced Parkinson's disease by subthalamotomy: One-year results
    • P.C. Su, H.M. Tseng, H.M. Liu, R.F. Yen, and H.H. Liou Treatment of advanced Parkinson's disease by subthalamotomy: one-year results Mov. Disord. 18 2003 531 538
    • (2003) Mov. Disord. , vol.18 , pp. 531-538
    • Su, P.C.1    Tseng, H.M.2    Liu, H.M.3    Yen, R.F.4    Liou, H.H.5
  • 136
    • 27744480730 scopus 로고    scopus 로고
    • Cell transplantation and gene therapy for the treatment of Parkinson's disease
    • N. Galvez-Jimenez Taylor and Francis London
    • T. Subramanian, and M. Deogaonkar Cell transplantation and gene therapy for the treatment of Parkinson's disease N. Galvez-Jimenez Scientific Basis for the Treatment of Parkinson's Disease 2005 Taylor and Francis London 233 250
    • (2005) Scientific Basis for the Treatment of Parkinson's Disease , pp. 233-250
    • Subramanian, T.1    Deogaonkar, M.2
  • 137
    • 2342581472 scopus 로고    scopus 로고
    • Upregulation of striatal adenosine A2A receptor mRNA in 6-hydroxydopamine-lesioned rats intermittently treated with l-DOPA
    • M. Tomiyama, T. Kimura, T. Maeda, H. Tanaka, K. Kannari, and M. Baba Upregulation of striatal adenosine A2A receptor mRNA in 6-hydroxydopamine- lesioned rats intermittently treated with l-DOPA Synapse 52 2004 218 222
    • (2004) Synapse , vol.52 , pp. 218-222
    • Tomiyama, M.1    Kimura, T.2    Maeda, T.3    Tanaka, H.4    Kannari, K.5    Baba, M.6
  • 138
    • 22144443869 scopus 로고    scopus 로고
    • The effect of levetiracetam on levodopa induced dyskinesias in patients with Parkinson's disease
    • (in press).
    • Tousi B., Subramanian, T., The effect of levetiracetam on levodopa induced dyskinesias in patients with Parkinson's disease, Parkinsonism Relat. Disord. (in press).
    • Parkinsonism Relat. Disord.
    • Tousi, B.1    Subramanian, T.2
  • 139
    • 0031574371 scopus 로고    scopus 로고
    • Behavioural sensitization in 6-hydroxydopamine-lesioned rats is related to compositional changes of the AP-1 transcription factor: Evidence for induction of FosB- and JunD-related proteins
    • D. Vallone, M.T. Pellecchia, M. Morelli, P. Verde, G. DiChiara, and P. Barone Behavioural sensitization in 6-hydroxydopamine-lesioned rats is related to compositional changes of the AP-1 transcription factor: evidence for induction of FosB- and JunD-related proteins Brain Res. Mol. Brain Res. 52 1997 307 317
    • (1997) Brain Res. Mol. Brain Res. , vol.52 , pp. 307-317
    • Vallone, D.1    Pellecchia, M.T.2    Morelli, M.3    Verde, P.4    Dichiara, G.5    Barone, P.6
  • 141
    • 0032708888 scopus 로고    scopus 로고
    • The phenomenology of l-dopa-induced dyskinesias in Parkinson's disease
    • M. Vidailhet, A.M. Bonnet, R. Marconi, F. Durif, and Y. Agid The phenomenology of l-dopa-induced dyskinesias in Parkinson's disease Mov. Disord. 1 1999 13 18
    • (1999) Mov. Disord. , vol.1 , pp. 13-18
    • Vidailhet, M.1    Bonnet, A.M.2    Marconi, R.3    Durif, F.4    Agid, Y.5
  • 143
    • 0030463523 scopus 로고    scopus 로고
    • Functional and pathophysiological models of the basal ganglia
    • T. Wichmann, and M.R. DeLong Functional and pathophysiological models of the basal ganglia Curr. Opin. Neurobiol. 6 1996 751 758
    • (1996) Curr. Opin. Neurobiol. , vol.6 , pp. 751-758
    • Wichmann, T.1    Delong, M.R.2
  • 144
    • 0037208608 scopus 로고    scopus 로고
    • Functional neuroanatomy of the basal ganglia in Parkinson's disease
    • T. Wichmann, and M.R. DeLong Functional neuroanatomy of the basal ganglia in Parkinson's disease Adv. Neurol. 91 2003 9 18
    • (2003) Adv. Neurol. , vol.91 , pp. 9-18
    • Wichmann, T.1    Delong, M.R.2
  • 145
    • 0036070538 scopus 로고    scopus 로고
    • L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: Relation to motor and cellular parameters of nigrostriatal function
    • C. Winkler, D. Kirik, A. Bjorklund, and M.A. Cenci l-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function Neurobiol. Dis. 10 2002 165 186
    • (2002) Neurobiol. Dis. , vol.10 , pp. 165-186
    • Winkler, C.1    Kirik, D.2    Bjorklund, A.3    Cenci, M.A.4
  • 146
    • 0027945523 scopus 로고
    • Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses
    • M. Xu, R. Moratalla, L.H. Gold, N. Hiroi, G.F. Koob, A.M. Graybiel, and S. Tonegawa Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses Cell 79 1994 729 742
    • (1994) Cell , vol.79 , pp. 729-742
    • Xu, M.1    Moratalla, R.2    Gold, L.H.3    Hiroi, N.4    Koob, G.F.5    Graybiel, A.M.6    Tonegawa, S.7
  • 148
    • 0034103771 scopus 로고    scopus 로고
    • Alterations in preproenkephalin and adenosine-2a receptor mRNA, but not preprotachykinin mRNA correlate with occurrence of dyskinesia in normal monkeys chronically treated with l-DOPA
    • B.Y. Zeng, R.K. Pearce, G.M. MacKenzie, and P. Jenner Alterations in preproenkephalin and adenosine-2a receptor mRNA, but not preprotachykinin mRNA correlate with occurrence of dyskinesia in normal monkeys chronically treated with l-DOPA Eur. J. Neurosci. 12 2000 1096 1104
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 1096-1104
    • Zeng, B.Y.1    Pearce, R.K.2    MacKenzie, G.M.3    Jenner, P.4
  • 149
    • 0346155930 scopus 로고    scopus 로고
    • Modafinil prevents the MPTP-induced increase in GABAA receptor binding in the internal globus pallidus of MPTP-treated common marmosets
    • B.Y. Zeng, L.A. Smith, R.K. Pearce, B. Tel, L. Chancharme, G. Moachon, and P. Jenner Modafinil prevents the MPTP-induced increase in GABAA receptor binding in the internal globus pallidus of MPTP-treated common marmosets Neurosci. Lett. 354 2004 6 9
    • (2004) Neurosci. Lett. , vol.354 , pp. 6-9
    • Zeng, B.Y.1    Smith, L.A.2    Pearce, R.K.3    Tel, B.4    Chancharme, L.5    Moachon, G.6    Jenner, P.7


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