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Volumn 16, Issue 4, 2001, Pages 708-713

Idazoxan, an alpha-2 antagonist, and L-DOPA-induced dyskinesias in patients with Parkinson's disease

Author keywords

2 receptors; Dyskinesia; Idazoxan; L DOPA; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; AMANTADINE; APOMORPHINE; BROMOCRIPTINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CLOZAPINE; DOPAMINE RECEPTOR STIMULATING AGENT; EFAROXAN; IDAZOXAN; LEVODOPA; LISURIDE; PLACEBO; RAUWOLSCINE; SELEGILINE; YOHIMBINE;

EID: 0035412888     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/mds.1143     Document Type: Article
Times cited : (156)

References (38)
  • 1
    • 0032736042 scopus 로고    scopus 로고
    • L-dopa-induced peak-dose dyskinesias in patients with Parkinson's disease: A clinical pharmacologic approach
    • Rascol O. L-dopa-induced peak-dose dyskinesias in patients with Parkinson's disease: a clinical pharmacologic approach. Mov Disorders 1999;14:19-32.
    • (1999) Mov. Disorders , vol.14 , pp. 19-32
    • Rascol, O.1
  • 2
    • 0034126269 scopus 로고    scopus 로고
    • Medical treatment of levodopa-induced dyskinesias
    • Rascol O. Medical treatment of levodopa-induced dyskinesias. Ann Neurol 2000;47:S179-S188.
    • (2000) Ann. Neurol. , vol.47
    • Rascol, O.1
  • 4
    • 0027384928 scopus 로고
    • Effect of non dopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys
    • Gomez-Mancilla B, Bédard PJ. Effect of non dopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys. Clin Neuropharmacol 1993;16:418-427.
    • (1993) Clin. Neuropharmacol. , vol.16 , pp. 418-427
    • Gomez-Mancilla, B.1    Bédard, P.J.2
  • 5
    • 0000129986 scopus 로고    scopus 로고
    • Alpha-2-adrenergic receptor antagonists reduce symptoms in animal models of L-dopa-induced dyskinesia
    • Henry B, Plowright A, Fox SH, et al. Alpha-2-adrenergic receptor antagonists reduce symptoms in animal models of L-dopa-induced dyskinesia. Soc Neurosci Abst 1997;23:742.
    • (1997) Soc. Neurosci. Abst. , vol.23 , pp. 742
    • Henry, B.1    Plowright, A.2    Fox, S.H.3
  • 6
    • 0032588996 scopus 로고    scopus 로고
    • The α2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances antiparkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease
    • Henry B, Fox S, Peggs D, Crossman A, Brotchie J. The α2-adrenergic receptor antagonist idazoxan reduces dyskinesia and enhances antiparkinsonian actions of L-dopa in the MPTP-lesioned primate model of Parkinson's disease. Mov Disorders 1999;14: 744-753.
    • (1999) Mov. Disorders , vol.14 , pp. 744-753
    • Henry, B.1    Fox, S.2    Peggs, D.3    Crossman, A.4    Brotchie, J.5
  • 7
    • 0033967659 scopus 로고    scopus 로고
    • Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys
    • Grondin R, Hadj Tahar A, Doan VD, Ladure P, Bedard PJ. Noradrenoceptor antagonism with idazoxan improves L-dopa-induced dyskinesias in MPTP monkeys. Arch Pharmacol 2000;361:181-186.
    • (2000) Arch. Pharmacol. , vol.361 , pp. 181-186
    • Grondin, R.1    Hadj Tahar, A.2    Doan, V.D.3    Ladure, P.4    Bedard, P.J.5
  • 8
    • 0025935168 scopus 로고
    • Differential modulation of (+) amphetamine-induced rotation in unilateral substancia nigra-lesioned rats by α1 as to compared to α2 agonists and antagonists
    • Mavridis M, Colpaert FC, Millan MJ. Differential modulation of (+) amphetamine-induced rotation in unilateral substancia nigra-lesioned rats by α1 as to compared to α2 agonists and antagonists. Brain Res 1991;562:216-224.
    • (1991) Brain Res. , vol.562 , pp. 216-224
    • Mavridis, M.1    Colpaert, F.C.2    Millan, M.J.3
  • 9
    • 0033064450 scopus 로고    scopus 로고
    • Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway
    • Chopin P, Colpaert FC, Marien M. Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J Pharmacol Exp Ther 1999;288:798-804.
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 798-804
    • Chopin, P.1    Colpaert, F.C.2    Marien, M.3
  • 11
    • 0012264019 scopus 로고
    • Short term oral administration of idazoxan in mild stable parkinsonian patients treated with L-dopa
    • Peyro-Saint-Paul H, Durif F, Pollak P, Bonnet AM, et al. Short term oral administration of idazoxan in mild stable parkinsonian patients treated with L-dopa. Therapie 1995;suppl 1:172.
    • (1995) Therapie , Issue.SUPPL. 1 , pp. 172
    • Peyro-Saint-Paul, H.1    Durif, F.2    Pollak, P.3    Bonnet, A.M.4
  • 12
    • 0000621211 scopus 로고    scopus 로고
    • Efficacy and safety of efaroxan, an alpha-2 adrenoceptor antagonist, in Parkinson's disease: An oral short-term study
    • Ruzicka E, Ladure P, Roth J, Jech R, Mecin P, Peyro-Saint Paul H. Efficacy and safety of efaroxan, an alpha-2 adrenoceptor antagonist, in Parkinson's disease: an oral short-term study. Move Disord 1997;12:S123.
    • (1997) Move. Disord. , vol.12
    • Ruzicka, E.1    Ladure, P.2    Roth, J.3    Jech, R.4    Mecin, P.5    Peyro-Saint Paul, H.6
  • 13
    • 0034123913 scopus 로고    scopus 로고
    • Idazoxan is ineffective for levodopa-induced dyskinesias in Parkinson's disease
    • Manson AJ, Iakovidou E, Lees AJ. Idazoxan is ineffective for levodopa-induced dyskinesias in Parkinson's disease. Mov Disord 2000;15:336-337.
    • (2000) Mov. Disord. , vol.15 , pp. 336-337
    • Manson, A.J.1    Iakovidou, E.2    Lees, A.J.3
  • 14
    • 0023898945 scopus 로고
    • The relevance of Lewy body to the pathogenesis of idiopathic Parkinson's disease
    • Lees AJ. The relevance of Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry 1988; 51:144-147.
    • (1988) J. Neurol. Neurosurg. Psychiatry , vol.51 , pp. 144-147
    • Lees, A.J.1
  • 15
    • 0000224448 scopus 로고
    • Unified Parkinson's disease rating scale
    • and Unified Parkinson's Disease Rating Scale Development Committee. Fahn S, Marsden CD, Calne D, editors. New York: Macmillan
    • Fahn S, Elton R, and Unified Parkinson's Disease Rating Scale Development Committee. Unified Parkinson's disease rating scale. In: Fahn S, Marsden CD, Calne D, editors. Recent developments in Parkinson's disease. New York: Macmillan, 1987;2:153-163.
    • (1987) Recent Developments in Parkinson's Disease , vol.2 , pp. 153-163
    • Fahn, S.1    Elton, R.2
  • 16
    • 0014082977 scopus 로고
    • Parkinsonism: Onset, progression and mortality
    • Hoehn M, Yahr M. Parkinsonism: onset, progression and mortality. Neurology 1967;17:427-442.
    • (1967) Neurology , vol.17 , pp. 427-442
    • Hoehn, M.1    Yahr, M.2
  • 17
    • 0030941117 scopus 로고    scopus 로고
    • Low-dose clozapine improves dyskinesias in Parkinson's disease
    • Durif F, Vidhailet M, Roche C, Bonnet AM, Agid Y. Low-dose clozapine improves dyskinesias in Parkinson's disease. Neurology 1996;48:658-662.
    • (1996) Neurology , vol.48 , pp. 658-662
    • Durif, F.1    Vidhailet, M.2    Roche, C.3    Bonnet, A.M.4    Agid, Y.5
  • 18
    • 0026551551 scopus 로고
    • Levodopa-induced dyskinesias in Parkinson's disease: Clinical and pharmacological classification
    • Luquin MR, Scipioni O, Vaamonde J, Gershanik O, Obeso JA. Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification. Mov Disord 1992;7:117-124.
    • (1992) Mov. Disord. , vol.7 , pp. 117-124
    • Luquin, M.R.1    Scipioni, O.2    Vaamonde, J.3    Gershanik, O.4    Obeso, J.A.5
  • 20
    • 0032736128 scopus 로고    scopus 로고
    • Dyskinesias assessment workshop: Reports from the working groups
    • Melamed E, Olanow CW, Nutt JG, Lang AE. Dyskinesias assessment workshop: reports from the working groups. Mov Disord 1999;14:69-73.
    • (1999) Mov. Disord. , vol.14 , pp. 69-73
    • Melamed, E.1    Olanow, C.W.2    Nutt, J.G.3    Lang, A.E.4
  • 21
    • 0012219326 scopus 로고
    • A new look at geometry
    • New York: The John Day Company
    • Adler I. A new look at geometry. New York: The John Day Company; 1966.
    • (1966)
    • Adler, I.1
  • 22
    • 0026458624 scopus 로고
    • Bilateral fetal mesencephalic graphting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropiridine (MPTP)
    • Widner H, Tetrud J, Rehngrona S, et al. Bilateral fetal mesencephalic graphting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropiridine (MPTP). N Engl J Med 1992;327:1556-1563.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1556-1563
    • Widner, H.1    Tetrud, J.2    Rehngrona, S.3
  • 23
    • 4243627443 scopus 로고    scopus 로고
    • Ratings of dyskinesias in the CAPSIT-Program
    • NIPD Group
    • Widner H, Defer G, Levivier M, NIPD Group. Ratings of dyskinesias in the CAPSIT-Program. Mov Disord 1998;13:S94.
    • (1998) Mov. Disord. , vol.13
    • Widner, H.1    Defer, G.2    Levivier, M.3
  • 25
    • 0020629560 scopus 로고
    • Yohimbine induced anxiety and increased noradrenergic function in humans: Effects of diazepam and clonidine
    • Charney DS, Heninger GR, Redmond DE. Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine. Life Sci 1983;33:19-29.
    • (1983) Life Sci. , vol.33 , pp. 19-29
    • Charney, D.S.1    Heninger, G.R.2    Redmond, D.E.3
  • 26
    • 0012218526 scopus 로고
    • Emotion and movement
    • Garlick D, editor. Univ NSW, Sydney: Committee in postgraduate medical education
    • Marsden CD. Emotion and movement. In: Garlick D, editor. Proprioception, posture and emotion. Univ NSW, Sydney: Committee in postgraduate medical education; 1982. p 185-194.
    • (1982) Proprioception, Posture and Emotion , pp. 185-194
    • Marsden, C.D.1
  • 27
    • 0025911001 scopus 로고
    • Abscence of arterial hypertension despite chronic plasma noradrenaline elevation: Evidence for down-regulation of alpha-adrenoceptors. A case report
    • Senard JM, Durrieu G, Berlan M, Estan L, Valet P, Tran MA, Garrigues M, Montastruc JL. Abscence of arterial hypertension despite chronic plasma noradrenaline elevation: evidence for down-regulation of alpha-adrenoceptors. A case report. Fundam Clin Pharmacol 1991;5:291-298.
    • (1991) Fundam. Clin. Pharmacol. , vol.5 , pp. 291-298
    • Senard, J.M.1    Durrieu, G.2    Berlan, M.3    Estan, L.4    Valet, P.5    Tran, M.A.6    Garrigues, M.7    Montastruc, J.L.8
  • 28
    • 0031853557 scopus 로고    scopus 로고
    • Efaroxan, an alpha-2 antagonist, in the treatment of Progressive Supranuclear Palsy
    • Rascol O, Sieardzan K, Peyro-Saint-Paul H, et al. Efaroxan, an alpha-2 antagonist, in the treatment of Progressive Supranuclear Palsy. Mov Disord 1998;13:673-676.
    • (1998) Mov. Disord. , vol.13 , pp. 673-676
    • Rascol, O.1    Sieardzan, K.2    Peyro-Saint-Paul, H.3
  • 29
    • 0027171165 scopus 로고
    • Suppression of dyskinesias in advanced Parkinson's disease: Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease
    • Schuh LA, Bennett JP. Suppression of dyskinesias in advanced Parkinson's disease: continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease. Neurology 1993;43:1545-1550.
    • (1993) Neurology , vol.43 , pp. 1545-1550
    • Schuh, L.A.1    Bennett, J.P.2
  • 31
    • 0029591229 scopus 로고
    • Imidazoline receptors: From basic concepts to recent developments
    • Bousquet P. Imidazoline receptors: from basic concepts to recent developments. J Cardiovasc Pharmacol 1995;26 (suppl 2):S1-S6.
    • (1995) J. Cardiovasc. Pharmacol. , vol.26 , Issue.SUPPL. 2
    • Bousquet, P.1
  • 32
    • 0028986788 scopus 로고
    • Localization of I2-imidazoline binding sites on monoamine oxidases
    • Tesson F, Limon-Boulez I, Urban P, et al. Localization of I2-imidazoline binding sites on monoamine oxidases. J Biochem 1995;270:9856-9861.
    • (1995) J. Biochem. , vol.270 , pp. 9856-9861
    • Tesson, F.1    Limon-Boulez, I.2    Urban, P.3
  • 34
    • 0024964228 scopus 로고
    • Catecholamine innervation of the human cerbral cortex as revealed by comparative immunohistochemistry of tyrosine hydroxylase and dopamine-beta-hydroxylase
    • Gaspar P, Berger B, Febvret A, Vigny A, Henry JP. Catecholamine innervation of the human cerbral cortex as revealed by comparative immunohistochemistry of tyrosine hydroxylase and dopamine-beta-hydroxylase. J Comp Neurol 1989;279:249-271.
    • (1989) J. Comp. Neurol. , vol.279 , pp. 249-271
    • Gaspar, P.1    Berger, B.2    Febvret, A.3    Vigny, A.4    Henry, J.P.5
  • 35
    • 0026046072 scopus 로고
    • Alterations of dopaminergic and noradrenergic innervations in motor cortex in Parkinson's disease
    • Gaspar P, Duyackaerts C, Alvarez C, Javoy-Agid F, Berger B. Alterations of dopaminergic and noradrenergic innervations in motor cortex in Parkinson's disease. Ann Neurol 1991;30:365-374.
    • (1991) Ann. Neurol. , vol.30 , pp. 365-374
    • Gaspar, P.1    Duyackaerts, C.2    Alvarez, C.3    Javoy-Agid, F.4    Berger, B.5
  • 36
    • 0017189213 scopus 로고
    • The roles of noradrenaline and dopamine in contraversive circling behaviour seen after unilateral electrolytic lesions of the locus coeruleus
    • Donaldson I, Dolphin A, Jenner P, Marsden CD, Pycock C. The roles of noradrenaline and dopamine in contraversive circling behaviour seen after unilateral electrolytic lesions of the locus coeruleus. Eur J Pharmacol 1976;39:179-191.
    • (1976) Eur. J. Pharmacol. , vol.39 , pp. 179-191
    • Donaldson, I.1    Dolphin, A.2    Jenner, P.3    Marsden, C.D.4    Pycock, C.5
  • 38
    • 0022631277 scopus 로고
    • The effects of yohimbine on exploratory and locomotor behavior are attributable to its effects at noradrenaline and not at benzodiazepine receptors
    • Chopin P, Pellow S, File SE. The effects of yohimbine on exploratory and locomotor behavior are attributable to its effects at noradrenaline and not at benzodiazepine receptors. Neuropharmacology 1986;25:53-57.
    • (1986) Neuropharmacology , vol.25 , pp. 53-57
    • Chopin, P.1    Pellow, S.2    File, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.