Burst bicycle exercise facilitates diagnosis of latent long QT syndrome

American Heart Journal

Volumn 150, Issue 5, 2005, Pages 1059-1063

  Walker, Bruce D ^a   Krahn, Andrew D ^a,b   Klein, George J ^a   Skanes, Allan C ^a   Yee, Raymond ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BICYCLE ERGOMETRY; CLINICAL ARTICLE; CLINICAL PROTOCOL; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIGITALIZATION; ELECTROCARDIOGRAM; FEMALE; GENOTYPE; HUMAN; LONG QT SYNDROME; MALE; PRIORITY JOURNAL; QT PROLONGATION; SENSITIVITY AND SPECIFICITY; WORKLOAD;

ADULT; EXERCISE TEST; FEMALE; HUMANS; LONG QT SYNDROME; MALE;

EID: 27744551049     PISSN: 00028703     EISSN: 10976744     Source Type: Journal    
DOI: 10.1016/j.ahj.2005.02.041     Document Type: Article

References (23)

1. S.G. Priori, C. Napolitano, and P.J. Schwartz Low penetrance of the long-QT syndrome: clinical impact Circulation 99 1999 529 533
2. P.J. Schwartz, S.G. Priori, and C. Spazzolini Genotype-phenotype correlation in the long QT syndrome. Gene specific triggers for life-threatening arrhythmias Circulation 103 2001 89 95
3. A.D. Krahn, J. Wang, and B. Spindler A novel mutation in KVLQT1, L122P, found in a family with autosomal dominant long QT syndrome Am Heart J 140 2000 146 149
4. P.J. Schwartz, A.J. Moss, and G.M. Vincent Diagnostic criteria for the long QT syndrome Circulation 88 1993 782 784
5. L. Arnold, J. Page, and D. Attwell The dependence on heart rate of the human ventricular action potential duration Cardiovasc Res 16 1982 547 551
6. L. Toivonen, K. Helenius, and M. Viitasalo Electrocardiographic repolarization during stress from awakening on alarm call J Am Coll Cardiol 30 1997 774 779
7. A.D. Krahn, G.J. Klein, and R. Yee Hysteresis of the RT interval with exercise: a new marker for the long-QT syndrome? Circulation 96 1997 1551 1556
8. A.D. Krahn, R. Yee, and V. Chauhan Beta blockers normalize QT hysteresis in long QT syndrome Am Heart J 143 2002 528 534
9. T. Eggeling, M. Hoeher, and H. Osterhues Significance of non-invasive diagnostic techniques in patients with long QT syndrome Am J Cardiol 70 1992 1421 1425
10. M. Katagiri-Kawade, T. Ohe, and Y. Arakaki Abnormal response to exercise, face immersion, and isoproterenol in children with the long QT syndrome Pacing Clin Electrophysiol 18 1995 2128 2134
11. W. Shimizu, T. Ohe, and T. Kurita Differential response of QTU interval to exercise, isoproterenol and atrial pacing in patients with congenital long QT syndrome Pacing Clin Electrophysiol 14 1991 1966 1970
12. M.J. Ackerman, A. Khositseth, and D.J. Tester Epinephrine-induced QT interval prolongation: a gene specific response in congenital long QT syndrome Mayo Clin Proc 77 2002 413 421
13. A.J. Moss, W. Zareba, and E.S. Kaufman Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel Circulation 105 2002 794 799
14. A.J. Moss Long QT syndrome: more questions J Cardiovasc Electrophysiol 12 2001 462
15. G.M. Vincent, K.W. Timothy, and M. Leppert The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome N Engl J Med 327 1992 846 850
16. J. Kimbrough, A.J. Moss, and W. Zareba Clinical implications for affected parents and siblings of probands with long-QT syndrome Circulation 104 2001 557 562
17. P. Yang, H. Kanki, and B. Drolet Allelic variants in long-QT disease genes in patients with drug-associated torsade de pointes Circulation 105 2002 1943 1948
18. I. Splawski, K.W. Timothy, and G.M. Vincent Molecular basis of the long-QT syndrome associated with deafness N Engl J Med 336 1997 1562 1567
19. E.S. Kaufman, S.G. Priori, and C. Napolitano Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome J Cardiovasc Electrophysiol 4 2001 455 461
20. W. Shimizu, T. Noda, and H. Takaki Epinephrine unmasks latent mutation carriers with LQT1 form of congenital long-QT syndrome J Am Coll Cardiol 41 2003 633 642
21. J. Karjalainen, M. Viitasalo, and M. Manttari Relation between QT intervals and heart rates from 40 to 120 beats/min in rest electrocardiograms of men and a simple method to adjust QT intervals J Am Coll Cardiol 23 1994 1547 1553
22. M. Iacoviello, F. Massari, and D. De Laura Influence of hydrophilic and lipophilic beta-blockers on heart rate, ventricular repolarization and their interrelationship in normal subjects Ital Heart J 1 2000 331 335
23. F. Extramiana, P. Maison-Blanche, and R. Tavernier Cardiac effects of chronic oral beta-blockade: lack of agreement between heart rate and QT interval changes Ann Noninvasive Electrocardiol 7 2002 379 388