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Volumn 6, Issue 2, 2000, Pages 585-596

In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD34 ANTIGEN; DNA; IMMUNOGLOBULIN HEAVY CHAIN;

EID: 0033977906     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (31)

References (53)
  • 1
    • 0018552079 scopus 로고
    • Treatment of plasma cell myeloma
    • Bergsagel, D. E. Treatment of plasma cell myeloma. Ann. Rev. Med., 30: 431-433, 1979.
    • (1979) Ann. Rev. Med. , vol.30 , pp. 431-433
    • Bergsagel, D.E.1
  • 2
    • 0024552490 scopus 로고
    • Reassessment of the relationship between M-protein decrement and survival in multiple myeloma
    • Palmer, M., Belch, A., Hanson, J., and Brox, L. Reassessment of the relationship between M-protein decrement and survival in multiple myeloma. Br. J. Cancer, 59: 110-112, 1989.
    • (1989) Br. J. Cancer , vol.59 , pp. 110-112
    • Palmer, M.1    Belch, A.2    Hanson, J.3    Brox, L.4
  • 4
    • 0343309958 scopus 로고
    • Circulating, monoclonal, multi-drug resistant B cells may comprise the malignant stem cells population in multiple myeloma
    • F. Dammaco and B. Barlogie (eds.)
    • Pilarski, L. M., Mant, M. J., and Belch, A. R. Circulating, monoclonal, multi-drug resistant B cells may comprise the malignant stem cells population in multiple myeloma. In: F. Dammaco and B. Barlogie (eds.), Challenges in Modern Medicine, Vol. 4, pp. 31-39, 1994.
    • (1994) Challenges in Modern Medicine , vol.4 , pp. 31-39
    • Pilarski, L.M.1    Mant, M.J.2    Belch, A.R.3
  • 5
    • 0025820771 scopus 로고
    • Selective expression of CD45 isoforms defines CALLA+ monoclonal B lineage cells in peripheral blood from myeloma patients as late stage B cells
    • Jensen, G. S., Mant, M. J., Belch, A. R., Berensen, J. R., Ruether, B. A., and Pilarski, L. M. Selective expression of CD45 isoforms defines CALLA+ monoclonal B lineage cells in peripheral blood from myeloma patients as late stage B cells. Blood, 78: 711-719, 1991.
    • (1991) Blood , vol.78 , pp. 711-719
    • Jensen, G.S.1    Mant, M.J.2    Belch, A.R.3    Berensen, J.R.4    Ruether, B.A.5    Pilarski, L.M.6
  • 6
    • 0026552179 scopus 로고
    • Monoclonal circulating B cells in multiple myeloma: A continuously differentiating possibly invasive population as defined by expression of CD45 isoforms and adhesion molecules
    • Pilarski, L. M., and Jensen, G. S. Monoclonal circulating B cells in multiple myeloma: a continuously differentiating possibly invasive population as defined by expression of CD45 isoforms and adhesion molecules. Hematol. Oncol. Clin. N. Am., 6: 297-322, 1992.
    • (1992) Hematol. Oncol. Clin. N. Am. , vol.6 , pp. 297-322
    • Pilarski, L.M.1    Jensen, G.S.2
  • 7
    • 0031036891 scopus 로고    scopus 로고
    • CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ rearrangements
    • Szczepek, A. J., Bergsagel, P. L., Axelsson, L., Brown, C. B., Belch, A. R., and Pilarski, L. M. CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ rearrangements. Blood, 89: 1824-1833, 1997.
    • (1997) Blood , vol.89 , pp. 1824-1833
    • Szczepek, A.J.1    Bergsagel, P.L.2    Axelsson, L.3    Brown, C.B.4    Belch, A.R.5    Pilarski, L.M.6
  • 8
    • 0030736702 scopus 로고    scopus 로고
    • Deficient drug transporter function of bone marrow-localized and leukemic plasma cells in multiple myeloma
    • Pilarski, L. M., Szczepek, A. J., and Belch, A. R. Deficient drug transporter function of bone marrow-localized and leukemic plasma cells in multiple myeloma. Blood, 90: 3751-3759, 1997.
    • (1997) Blood , vol.90 , pp. 3751-3759
    • Pilarski, L.M.1    Szczepek, A.J.2    Belch, A.R.3
  • 9
    • 0030045099 scopus 로고    scopus 로고
    • Hyaluronan-dependent motility of B cells and leukemic plasma cells but not of bone marrow plasma cells in multiple myeloma: Alternate usage of RHAMM and CD44
    • Masellis-Smith, A., Belch, A. R., Mant, M. J., Turley, E. A., and Pilarski, L. M. Hyaluronan-dependent motility of B cells and leukemic plasma cells but not of bone marrow plasma cells in multiple myeloma: alternate usage of RHAMM and CD44. Blood, 87: 1891-1899, 1996.
    • (1996) Blood , vol.87 , pp. 1891-1899
    • Masellis-Smith, A.1    Belch, A.R.2    Mant, M.J.3    Turley, E.A.4    Pilarski, L.M.5
  • 10
    • 0032531999 scopus 로고    scopus 로고
    • A high frequency of circulating B cells share clonotypic IgH VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single cell and in situ RT-PCR
    • Szczepek, A. J., Seeberger, K., Wizniak, J., Mant, M. J., Belch, A. R., and Pilarski, L. M. A high frequency of circulating B cells share clonotypic IgH VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single cell and in situ RT-PCR. Blood, 92: 2844-2855, 1998.
    • (1998) Blood , vol.92 , pp. 2844-2855
    • Szczepek, A.J.1    Seeberger, K.2    Wizniak, J.3    Mant, M.J.4    Belch, A.R.5    Pilarski, L.M.6
  • 11
    • 0028908877 scopus 로고
    • In multiple myeloma, clonotypic B lymphocytes are detectable among CD19+ peripheral blood cells expressing CD38, CD56, and monotypic immunoglobulin light chain
    • Bergsagel, P. L., Masellis, S., Szczepek, A., Mant, M. J., Belch, A. R., and Pilarski, L. M. In multiple myeloma, clonotypic B lymphocytes are detectable among CD19+ peripheral blood cells expressing CD38, CD56, and monotypic immunoglobulin light chain. Blood, 85: 436-447, 1995.
    • (1995) Blood , vol.85 , pp. 436-447
    • Bergsagel, P.L.1    Masellis, S.2    Szczepek, A.3    Mant, M.J.4    Belch, A.R.5    Pilarski, L.M.6
  • 13
    • 24544466082 scopus 로고    scopus 로고
    • Evidence that myeloma may originate from an antigen-driven clone that persists after malignant transformation: Pre-switch B cells in the circulation of myeloma patients exhibit mutational diversity in the variable region of clonal IgM and IgD transcripts
    • Szczepek, A. J., Belch, A. R., and Pilarski, L. M. Evidence that myeloma may originate from an antigen-driven clone that persists after malignant transformation: pre-switch B cells in the circulation of myeloma patients exhibit mutational diversity in the variable region of clonal IgM and IgD transcripts. Blood, 92: 257a-257a, 1998.
    • (1998) Blood , vol.92
    • Szczepek, A.J.1    Belch, A.R.2    Pilarski, L.M.3
  • 14
    • 0028246112 scopus 로고
    • Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell
    • Bakkus, M. H. C., Van Riet, I., Van Camp, B., and Thielemann, K. Evidence that the clonogenic cell in multiple myeloma originates from a pre-switched but somatically mutated B cell. Br. J. Haematol., 87: 68-74, 1994.
    • (1994) Br. J. Haematol. , vol.87 , pp. 68-74
    • Bakkus, M.H.C.1    Van Riet, I.2    Van Camp, B.3    Thielemann, K.4
  • 15
    • 0027257608 scopus 로고
    • The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell
    • Billadeau, D., Ahmann, G., Greipp, P., and Van Ness, B. The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell. J. Exp. Med., 178: 1023-1031, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 1023-1031
    • Billadeau, D.1    Ahmann, G.2    Greipp, P.3    Van Ness, B.4
  • 16
    • 0027296754 scopus 로고
    • Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to c-mu sequence in immunoglobulin (IgG) and IgA secreting multiple myelomas
    • Corradini, P., Boccadoro, M., Voena, C., and Pilieri, A. Evidence for a bone marrow B cell transcribing malignant plasma cell VDJ joined to c-mu sequence in immunoglobulin (IgG) and IgA secreting multiple myelomas. J. Exp. Med., 178; 1091-1096, 1993.
    • (1993) J. Exp. Med. , vol.178 , pp. 1091-1096
    • Corradini, P.1    Boccadoro, M.2    Voena, C.3    Pilieri, A.4
  • 17
    • 0016192364 scopus 로고
    • Monoclonal lymphocytes in human plasma cell myeloma
    • Mellstedt, H., Hammarstrom, S., and Holm, G. Monoclonal lymphocytes in human plasma cell myeloma. Clin. Exp. Immunol., 17: 371-384, 1974.
    • (1974) Clin. Exp. Immunol. , vol.17 , pp. 371-384
    • Mellstedt, H.1    Hammarstrom, S.2    Holm, G.3
  • 18
    • 0024389383 scopus 로고
    • Tumor cell heterogeneity in multiple myeloma: Antigenic, morphologic, and functional studies of cells from blood and bone marrow
    • King, M. A., and Nelsonm, D. S. Tumor cell heterogeneity in multiple myeloma: antigenic, morphologic, and functional studies of cells from blood and bone marrow. Blood, 73: 1925-1935, 1989.
    • (1989) Blood , vol.73 , pp. 1925-1935
    • King, M.A.1    Nelsonm, D.S.2
  • 19
    • 0024243657 scopus 로고
    • Phenotypical and functional characterization of the idiotype-positive blood B cells in multiple myeloma
    • Bloem, A. C., Chand, M. A., van Camp, B., Bast, E. J., and Ballieux, R. E. Phenotypical and functional characterization of the idiotype-positive blood B cells in multiple myeloma. Scand. J. Immunol., 28: 791-799, 1988.
    • (1988) Scand. J. Immunol. , vol.28 , pp. 791-799
    • Bloem, A.C.1    Chand, M.A.2    Van Camp, B.3    Bast, E.J.4    Ballieux, R.E.5
  • 20
    • 0020093141 scopus 로고
    • Idiotype-bearing lymphoid cells in plasma cell neoplasia
    • Mellstedt, H., Holm, G., Pettersson, D., and Peest, D. Idiotype-bearing lymphoid cells in plasma cell neoplasia. Clin. Haematol., 11: 65-86, 1982.
    • (1982) Clin. Haematol. , vol.11 , pp. 65-86
    • Mellstedt, H.1    Holm, G.2    Pettersson, D.3    Peest, D.4
  • 21
    • 0025838831 scopus 로고
    • Establishment of idiotype bearing B-lymphocyte clones from a patient with monoclonal gammopathy
    • Osterborg, A., Steinitz, M., Lewin, N., Bergenbrant, S., Holm, G., Lefvert, A. K., and Mellstedt, H. Establishment of idiotype bearing B-lymphocyte clones from a patient with monoclonal gammopathy. Blood, 78: 2642-2649, 1991.
    • (1991) Blood , vol.78 , pp. 2642-2649
    • Osterborg, A.1    Steinitz, M.2    Lewin, N.3    Bergenbrant, S.4    Holm, G.5    Lefvert, A.K.6    Mellstedt, H.7
  • 22
    • 0018956010 scopus 로고
    • Monoclonal B lymphocytes in multiple myeloma
    • Pettersson, D., Mellstedt, H., and Holm, G. Monoclonal B lymphocytes in multiple myeloma. Scand. J. Immunol., 12: 375-382, 1980.
    • (1980) Scand. J. Immunol. , vol.12 , pp. 375-382
    • Pettersson, D.1    Mellstedt, H.2    Holm, G.3
  • 23
    • 0026687227 scopus 로고
    • Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients
    • Billadeau, D., Quam, L., Thomas, W., Kay, N. E., Greipp, P., Kyle, R., Oken, M. M., and Van Ness, B. Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients. Blood, 80: 1818-1824, 1992.
    • (1992) Blood , vol.80 , pp. 1818-1824
    • Billadeau, D.1    Quam, L.2    Thomas, W.3    Kay, N.E.4    Greipp, P.5    Kyle, R.6    Oken, M.M.7    Van Ness, B.8
  • 24
    • 0029957126 scopus 로고    scopus 로고
    • Clonal circulating cells are common in plasma cell proliferative disorders: A comparison of monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and active myeloma
    • Billadeau, D., Van Ness, B., Kimlinger, T., Kyle, R. A., Therneau, T. M., Greipp, P. R., and Witzig, T. E. Clonal circulating cells are common in plasma cell proliferative disorders: a comparison of monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and active myeloma. Blood, 88: 289-296, 1996.
    • (1996) Blood , vol.88 , pp. 289-296
    • Billadeau, D.1    Van Ness, B.2    Kimlinger, T.3    Kyle, R.A.4    Therneau, T.M.5    Greipp, P.R.6    Witzig, T.E.7
  • 25
    • 0029015660 scopus 로고    scopus 로고
    • Idiotypic oligonucleotide probes to detect myeloma cells by mRNA in situ hybridization
    • Brown, R., Luo, X. F., Gibson, J., Morley, A., Sykes, P., Brisco, M., and Joshua, D. Idiotypic oligonucleotide probes to detect myeloma cells by mRNA in situ hybridization. Br. J. Haematol., 90: 113-118, 1998.
    • (1998) Br. J. Haematol. , vol.90 , pp. 113-118
    • Brown, R.1    Luo, X.F.2    Gibson, J.3    Morley, A.4    Sykes, P.5    Brisco, M.6    Joshua, D.7
  • 26
    • 0030049654 scopus 로고    scopus 로고
    • Circulating clonal lymphocytes in myeloma constitute a minor population of B cells
    • Chen, B. J., and Epstein, J. Circulating clonal lymphocytes in myeloma constitute a minor population of B cells. Blood, 87: 1972-1976, 1996.
    • (1996) Blood , vol.87 , pp. 1972-1976
    • Chen, B.J.1    Epstein, J.2
  • 27
    • 84929564445 scopus 로고    scopus 로고
    • Myeloma progenitors in the blood of patients with aggressive or minimal disease: Engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice
    • in press
    • Pilarski, L. M., Hipperson, G., Seeberger, K., Pruski, E., Coupland, R. W., and Belch, A. R. Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice. Blood, in press, 1999.
    • (1999) Blood
    • Pilarski, L.M.1    Hipperson, G.2    Seeberger, K.3    Pruski, E.4    Coupland, R.W.5    Belch, A.R.6
  • 28
    • 0029946705 scopus 로고    scopus 로고
    • Tumor-specific aneuploidy not detected in CD19+ B lymphoid cells from myeloma patients in a multidimensional flow cytometry analysis
    • McSweeney, P. A., Wells, D. A., Shults, K. E., Nash, R. A., Bensinger, W. I., Buckner, C. D., and Loken, M. R. Tumor-specific aneuploidy not detected in CD19+ B lymphoid cells from myeloma patients in a multidimensional flow cytometry analysis. Blood, 88: 622-632, 1996.
    • (1996) Blood , vol.88 , pp. 622-632
    • McSweeney, P.A.1    Wells, D.A.2    Shults, K.E.3    Nash, R.A.4    Bensinger, W.I.5    Buckner, C.D.6    Loken, M.R.7
  • 30
    • 0021335916 scopus 로고
    • Plasma cell DNA content in multiple myeloma and related paraproteinemic disorders. Relationship with clinical and cytokinetic features
    • Montecucco, C., Riccardi, A., Merlini, G., Mazzini, G., Giordano, P., Danova, M., and Ascari, E. Plasma cell DNA content in multiple myeloma and related paraproteinemic disorders. Relationship with clinical and cytokinetic features. Br. J. Cancer Clin. Oncol., 20: 81-90, 1984.
    • (1984) Br. J. Cancer Clin. Oncol. , vol.20 , pp. 81-90
    • Montecucco, C.1    Riccardi, A.2    Merlini, G.3    Mazzini, G.4    Giordano, P.5    Danova, M.6    Ascari, E.7
  • 31
    • 0024551187 scopus 로고
    • Detection of hypodiploidy using multiparameter flow cytometric analysis: A prognostic indicator in multiple myeloma
    • Morgan, R. J., Jr., Gonchoroff, N. J., Katzmann, J. A., Witzig, T. E., Kyle, R. A., and Greipp, P. R. Detection of hypodiploidy using multiparameter flow cytometric analysis: a prognostic indicator in multiple myeloma. Am. J. Hematol., 30: 195-200, 1989.
    • (1989) Am. J. Hematol. , vol.30 , pp. 195-200
    • Morgan R.J., Jr.1    Gonchoroff, N.J.2    Katzmann, J.A.3    Witzig, T.E.4    Kyle, R.A.5    Greipp, P.R.6
  • 32
    • 0026572260 scopus 로고
    • Flow cytometric DNA analysis and clinical correlations in multiple myeloma
    • Tienhaara, A., and Pelliniemi, T. T. Flow cytometric DNA analysis and clinical correlations in multiple myeloma. Am. J. Clin. Pathol., 97: 322-330, 1992.
    • (1992) Am. J. Clin. Pathol. , vol.97 , pp. 322-330
    • Tienhaara, A.1    Pelliniemi, T.T.2
  • 34
    • 0025969581 scopus 로고
    • DNA and RNA flow cytometric study in multiple myeloma
    • Tafuri, A., Meyers, J., Lee, B. J., and Andreeff, M. DNA and RNA flow cytometric study in multiple myeloma. Cancer (Phila.), 67: 449-454: 1991.
    • (1991) Cancer (Phila.) , vol.67 , pp. 449-454
    • Tafuri, A.1    Meyers, J.2    Lee, B.J.3    Andreeff, M.4
  • 39
    • 0028168180 scopus 로고
    • RHAMM, a receptor for hyaluronan-mediated motility, on normal lymphocytes, thymocytes and in B cell malignancy: A mediator in B cell malignancy?
    • Pilarski, L. M., Masellis Smith, A., Belch, A. R., Yang, B., Savani, R. C., and Turley, E. A. RHAMM, a receptor for hyaluronan-mediated motility, on normal lymphocytes, thymocytes and in B cell malignancy: a mediator in B cell malignancy? Leuk. Lymphoma, 14: 363-374, 1994.
    • (1994) Leuk. Lymphoma , vol.14 , pp. 363-374
    • Pilarski, L.M.1    Masellis Smith, A.2    Belch, A.R.3    Yang, B.4    Savani, R.C.5    Turley, E.A.6
  • 40
    • 0027976530 scopus 로고
    • Circulating monoclonal B cells expressing p-glycoprotein may be a reservoir of multidrug resistant disease in multiple myeloma
    • Pilarski, L. M., and Belch, A. R. Circulating monoclonal B cells expressing p-glycoprotein may be a reservoir of multidrug resistant disease in multiple myeloma. Blood, 83: 724-736, 1994.
    • (1994) Blood , vol.83 , pp. 724-736
    • Pilarski, L.M.1    Belch, A.R.2
  • 41
    • 0019479971 scopus 로고
    • Mithramycin and 4′-6′-diamidino-2-phenylindole (DAPI)-DNA staining for fluorescence microspectrophotometric measurement of DNA in nuclei, plastids, and virus particles
    • Coleman, A. W., Maguire, M. J., and Coleman, J. R. Mithramycin and 4′-6′-diamidino-2-phenylindole (DAPI)-DNA staining for fluorescence microspectrophotometric measurement of DNA in nuclei, plastids, and virus particles. J. Histochem. Cytochem., 29: 959-968, 1981.
    • (1981) J. Histochem. Cytochem. , vol.29 , pp. 959-968
    • Coleman, A.W.1    Maguire, M.J.2    Coleman, J.R.3
  • 42
    • 0025131482 scopus 로고
    • Simultaneous measurement of DNA content and cell-surface immunofluorescence of human bone marrow cells using a single laser flow cytometer
    • Brons, P. P. T., Pennings, A. H. M., Haanen, C., Wessels, H. M. C., and Boezeman, J. B. M. Simultaneous measurement of DNA content and cell-surface immunofluorescence of human bone marrow cells using a single laser flow cytometer. Cytometry, 11: 837-844, 1990.
    • (1990) Cytometry , vol.11 , pp. 837-844
    • Brons, P.P.T.1    Pennings, A.H.M.2    Haanen, C.3    Wessels, H.M.C.4    Boezeman, J.B.M.5
  • 43
    • 0018076581 scopus 로고
    • Biology of the human myeloma cell population. II. Cytokinetic characteristics
    • Hulin, N., Conte, P. F., and Pileri, A. Biology of the human myeloma cell population. II. Cytokinetic characteristics. Clin. Lab., 8: 49-55, 1978.
    • (1978) Clin. Lab. , vol.8 , pp. 49-55
    • Hulin, N.1    Conte, P.F.2    Pileri, A.3
  • 44
    • 0028882866 scopus 로고
    • S-phase cells of the lymphoplasmocytic compartment in hyperdiploid multiple myeloma are diploid cells
    • Haraldsdottir, V., Haanen, C., Kalsbeek-Batenburg, E., and Olthuis, F. S-phase cells of the lymphoplasmocytic compartment in hyperdiploid multiple myeloma are diploid cells. Cytometry, 21: 203-210, 1995.
    • (1995) Cytometry , vol.21 , pp. 203-210
    • Haraldsdottir, V.1    Haanen, C.2    Kalsbeek-Batenburg, E.3    Olthuis, F.4
  • 46
    • 8944237001 scopus 로고    scopus 로고
    • Incidence of chromosome numerical changes in multiple myeloma Fluorescence in situ hybridization analysis using 15 chromosome-specific probes
    • Tabernero, D., San Miguel, J. F., Garcia-Sanz, R., Najera, L., Garcia-Isidoro, M., Perez-Simon, J. A., Raap, A. K., and Orfao, A. Incidence of chromosome numerical changes in multiple myeloma Fluorescence in situ hybridization analysis using 15 chromosome-specific probes. Am. J. Pathol., 149: 153-161, 1996.
    • (1996) Am. J. Pathol. , vol.149 , pp. 153-161
    • Tabernero, D.1    San Miguel, J.F.2    Garcia-Sanz, R.3    Najera, L.4    Garcia-Isidoro, M.5    Perez-Simon, J.A.6    Raap, A.K.7    Orfao, A.8
  • 47
    • 0030211192 scopus 로고    scopus 로고
    • Multiple myeloma: Almost all patients are cytogenetically abnormal
    • Zandecki, M., Lai, J. L., and Facon, T. Multiple myeloma: almost all patients are cytogenetically abnormal. Br. J. Haematol., 94: 217-227, 1996.
    • (1996) Br. J. Haematol. , vol.94 , pp. 217-227
    • Zandecki, M.1    Lai, J.L.2    Facon, T.3
  • 48
    • 0030790529 scopus 로고    scopus 로고
    • Involvement of peripheral blood cells in multiple myeloma: Chromosome changes are the rule within circulating plasma cells but not within B lymphocytes
    • Zandecki, M., Bernardi, F., Genevieve, F., Lai, J. L., Preudhomme, C., Flactif, M., Cosson, A., Bauters, F., and Facon, T. Involvement of peripheral blood cells in multiple myeloma: chromosome changes are the rule within circulating plasma cells but not within B lymphocytes. Leukemia, 11: 1034-1039, 1997.
    • (1997) Leukemia , vol.11 , pp. 1034-1039
    • Zandecki, M.1    Bernardi, F.2    Genevieve, F.3    Lai, J.L.4    Preudhomme, C.5    Flactif, M.6    Cosson, A.7    Bauters, F.8    Facon, T.9
  • 49
    • 0343309897 scopus 로고    scopus 로고
    • Cryptic expression of the CD19 epitope detected by mAb Leu12 distinguishes malignant from residual polyclonal B cells in the blood of myeloma patients
    • Pilarski, L. M., Szczepek, A. J., Mant, M. J., and Belch, A. R. Cryptic expression of the CD19 epitope detected by mAb Leu12 distinguishes malignant from residual polyclonal B cells in the blood of myeloma patients. Blood, 90: 349a-349a, 1997.
    • (1997) Blood , vol.90
    • Pilarski, L.M.1    Szczepek, A.J.2    Mant, M.J.3    Belch, A.R.4
  • 50
    • 0342440346 scopus 로고
    • Single cell IgH cdr3 and in situ RT-PCR for IgH CDR3 and Ig light chain unequivocally confirm that circulating CD19+ cells in multiple myeloma are B cells
    • Pilarski, L. M., Szczepek, A., MacDonald, H., Mant, M. J., and Belch, A. R. Single cell IgH CDR3 and in situ RT-PCR for IgH CDR3 and Ig light chain unequivocally confirm that circulating CD19+ cells in multiple myeloma are B cells. Blood, 86: 58a, 1995.
    • (1995) Blood , vol.86
    • Pilarski, L.M.1    Szczepek, A.2    MacDonald, H.3    Mant, M.J.4    Belch, A.R.5
  • 51
    • 0033104710 scopus 로고    scopus 로고
    • Overexpression of the hyaluronan receptor RHAMM characterizes the malignant clone in multiple myeloma: Identification of three distinct RHAMM isoforms
    • Crainie, M., Mant, M. J., Belch, A. R., and Pilarski, L. M. Overexpression of the hyaluronan receptor RHAMM characterizes the malignant clone in multiple myeloma: identification of three distinct RHAMM isoforms. Blood, 93: 1684-1696, 1999.
    • (1999) Blood , vol.93 , pp. 1684-1696
    • Crainie, M.1    Mant, M.J.2    Belch, A.R.3    Pilarski, L.M.4
  • 52
    • 0030890414 scopus 로고    scopus 로고
    • Expression of the hematopoietic stem cell antigen CD34 on blood and bone marrow monoclonal plasma cells from patients with multiple myeloma
    • Kimlinger, T., and Witzig, T. E. Expression of the hematopoietic stem cell antigen CD34 on blood and bone marrow monoclonal plasma cells from patients with multiple myeloma. Bone Marrow Transplant., 19: 553-556, 1997.
    • (1997) Bone Marrow Transplant. , vol.19 , pp. 553-556
    • Kimlinger, T.1    Witzig, T.E.2
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