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Volumn 6, Issue 11, 2005, Pages 1986-1990

Sunflower-shaped cyclodextrin-conjugated poly(ε-lysine) polyplex as a controlled intracellular trafficking device

Author keywords

Cyclodextrins; Gene therapy; Membranes; Proton sponge effect; Supramolecular chemistry

Indexed keywords

BETA CYCLODEXTRIN; CHOLESTEROL; PLASMID DNA; POLYLYSINE; PROTON;

EID: 27744500452     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200500242     Document Type: Article
Times cited : (23)

References (33)
  • 5
    • 0026718123 scopus 로고
    • a) A. D. Miller, Nature 1992, 357, 455;
    • (1992) Nature , vol.357 , pp. 455
    • Miller, A.D.1
  • 28
    • 20144378140 scopus 로고    scopus 로고
    • To prepare a stable polyplex, β-CDPL was dissolved in PBS at pH 6.0 and mixed with pDNA solution; this mixture was then diluted tenfold in PBS at pH 7.4. We confirmed that the polyplex was stable under these condition, in spite of the deprotonation of some of the β-CDPL secondary amines (Figure 1 d). Since the DLS data for the β-CDPL polyplexes were obtained under cation-rich conditions (N/P 10) there is a surplus of cations that are not involved in polyplex formation; this results in the split peaks; see H. S. Choi, T. Ooya, K. M. Huh, N. Yui, Biomacromolecules 2005, 6, 1200.
    • (2005) Biomacromolecules , vol.6 , pp. 1200
    • Choi, H.S.1    Ooya, T.2    Huh, K.M.3    Yui, N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.