Prostaglandin E2 induces cyclooxygenase-2 expression in human non-pigmented ciliary epithelial cells through activation of p38 and p42/44 mitogen-activated protein kinases

Biochemical and Biophysical Research Communications

Volumn 338, Issue 2, 2005, Pages 1171-1178

  Rösch, Susanne ^a   Ramer, Robert ^a   Brune, Kay ^a   Hinz, Burkhard ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Cyclooxygenase 2; EP receptors; Mitogen activated protein kinases; Non pigmented ciliary epithelial cells; Positive feedback regulation; Prostaglandin E2

Indexed keywords

6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; BISINDOLYLMALEIMIDE 2; BUTAPROST; CALCIUM CHELATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; ONO AE3 208; PROSTAGLANDIN E1; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; PROTEIN KINASE C INHIBITOR; SULPROSTONE; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; PTGS2 PROTEIN, HUMAN;

ARTICLE; CILIARY BODY EPITHELIUM; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTRAOCULAR PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; CILIARY BODY; CORNEA EPITHELIUM; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CILIARY BODY; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 27744460428     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.051     Document Type: Article

References (44)

1. R.N. Weinreb, C.B. Toris, B.T. Gabelt, J.D. Lindsey, and P.L. Kaufman Effects of prostaglandins on the aqueous humor outflow pathways Surv. Ophthalmol. 47 Suppl. 1 2002 S53 S54
2. 2α and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species Exp. Eye Res. 63 1996 305 310
3. 2 induction, affinity to prostaglandin transporter, and intraocular metabolism Exp. Eye Res. 74 2002 41 49
4. K. Kashiwagi, and S. Tsukahara Effect of non-steroidal anti-inflammatory ophthalmic solution on intraocular pressure reduction by latanoprost Br. J. Ophthalmol. 87 2003 297 301
5. B. Hinz, S. Rösch, R. Ramer, E.R. Tamm, and K. Brune Latanoprost induces matrix metalloproteinase-1 expression in human non-pigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism FASEB J. 2005 10.1096/fj.04-3626fje. [Epub ahead of print]
6. W.E. Sponsel, G. Paris, Y. Trigo, M. Pena, A. Weber, K. Sanford, and S. McKinnon Latanoprost and brimonidine: therapeutic and physiologic assessment before and after oral nonsteroidal anti-inflammatory therapy Am. J. Ophthalmol. 133 2002 11 18
7. 2 in the human and rabbit eye Eur. J. Ophthalmol. 13 2003 18 23
8. P. Bhattacherjee, and B.R. Hammond Effect of indomethacin on the ocular hypotensive action of adrenaline in the rabbit Exp. Eye Res. 24 1977 307 313
9. C.B. Camras, S.G. Feldman, S.M. Podos, R.E. Christensen, S.K. Gardner, and D.T. Fazio Inhibition of the epinephrine-induced reduction of intraocular pressure by systemic indomethacin in humans Am. J. Ophthalmol. 100 1985 169 175
10. D.W. Pate, K. Jarvinen, A. Urtti, P. Jarho, M. Fich, V. Mahadevan, and T. Jarvinen Effects of topical anandamides on intraocular pressure in normotensive rabbits Life Sci. 58 1996 1849 1860
11. 9-tetrahydrocannabinol and indomethacin Ophthalmic Res. 33 2001 217 220
12. C. Maihöfner, U. Schlötzer-Schrehardt, H. Gühring, H.U. Zeilhofer, G.O. Naumann, A. Pahl, C. Mardin, E.R. Tamm, and K. Brune Expression of cyclooxygenase-1 and -2 in normal and glaucomatous human eyes Invest. Ophthalmol. Vis. Sci. 42 2001 2616 2624
13. 3 subtype. Different COOH-terminal domains determine sensitivity to agonist-induced desensitization J. Biol. Chem. 268 1993 9517 9521
14. R.A. Coleman, S.P. Grix, S.A. Head, J.B. Louttit, A. Mallett, and R.L. Sheldrick A novel inhibitory prostanoid receptor in piglet saphenous vein Prostaglandins 47 1994 151 168
15. 2 analogue (U46619) and basic fibroblast growth factor in porcine aortic smooth-muscle cells Biochem. J. 326 1997 593 599
16. 2 and other cyclic AMP stimulants in J774 macrophages Biochem. Pharmacol. 53 1997 493 500
17. 2 through cAMP Mediators Inflamm. 8 1999 287 294
18. 2 on the induction of nitric oxide- and prostanoid-forming pathways in cultured rat mesangial cells Biochem. J. 313 1996 617 623
19. 2, cyclic AMP and non-steroidal anti-inflammatory drugs Eur. J. Neurosci. 9 1997 934 940
20. 2, and nonsteroidal anti-inflammatory drugs Biochem. Biophys. Res. Commun. 278 2000 790 796
21. 2 upregulates cyclooxygenase-2 expression in lipopolysaccharide-stimulated RAW 264.7 macrophages Biochem. Biophys. Res. Commun. 272 2000 744 748
22. 2 regulation of cyclooxygenase expression in keratinocytes is mediated via cyclic nucleotide-linked prostaglandin receptors J. Lipid Res. 41 2000 873 881
23. 1 subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells Calcif. Tissue Int. 62 1998 327 331
24. B.L. Diaz, H. Fujishima, Y. Kanaoka, Y. Urade, and J.P. Arm Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids J. Immunol. 168 2002 1397 1404
25. J.L. Dean, M. Brook, A.R. Clark, and J. Saklatvala p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes J. Biol. Chem. 274 1999 264 269
26. R. Ramer, K. Brune, A. Pahl, and B. Hinz R(+)-methanandamide induces cyclooxygenase-2 expression in human neuroglioma cells via a non-cannabinoid receptor-mediated mechanism Biochem. Biophys. Res. Commun. 286 2001 1144 1152
27. R. Ramer, U. Weinzierl, B. Schwind, K. Brune, and B. Hinz Ceramide is involved in R(+)-methanandamide-induced cyclooxygenase-2 expression in human neuroglioma cells Mol. Pharmacol. 64 2003 1189 1198
28. B. Hinz, R. Ramer, K. Eichele, U. Weinzierl, and K. Brune Upregulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells Mol. Pharmacol. 66 2004 1643 1651
29. 2 induces proliferation of glandular epithelial cells of the human endometrium via extracellular regulated kinase 1/2-mediated pathway J. Clin. Endocrinol. Metab. 88 2003 4481 4487
30. 4 receptor-evoked ERK activation J. Biol. Chem. 279 2004 29797 29804
31. 4 receptor-dependent activation of p42/44 MAPK and EGFR transactivation Am. J. Physiol. Heart Circ. Physiol. 288 2005 H2111 H2117
32. 2 induces interleukin-8 gene transcription by activating C/EBP homologous protein in human T lymphocytes J. Biol. Chem. 280 2005 14433 14442
33. 2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1β-treated human synovial fibroblasts J. Biol. Chem. 276 2001 31720 31731
34. 4-like receptors, p38 mitogen-activated protein kinase and protein kinase C J. Neurochem. 79 2001 950 958
35. W. Ma, and R. Quirion Up-regulation of interleukin-6 induced by prostaglandin E from invading macrophages following nerve injury: an in vivo and in vitro study J. Neurochem. 93 2005 664 673
36. 2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases J. Biol. Chem. 278 2003 12151 12156
37. 2 receptor in endometrial adenocarcinoma cells promotes vascular endothelial growth factor expression via cyclic 3′,5′-adenosine monophosphate-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase 1/2 signaling pathways Mol. Endocrinol. 18 2004 1533 1545
38. 2 receptor Mol. Cell. Endocrinol. 203 2003 77 90
39. 2 Cell Signal. 9 1997 531 537
40. 2 receptor activated Nur77 gene transcription Br. J. Pharmacol. 142 2004 737 748
41. D.F. Woodward, J.W. Regan, S. Lake, and A. Ocklind The molecular biology and ocular distribution of prostanoid receptors Surv. Ophthalmol. 41 Suppl. 2 1997 S15 S21
42. U. Schlötzer-Schrehardt, M. Zenkel, and R.M. Nusing Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues Invest. Ophthalmol. Vis. Sci. 43 2002 1475 1487
43. M. Richter, A.H. Krauss, D.F. Woodward, and E. Lütjen-Drecoll Morphological changes in the anterior eye segment after long-term treatment with different receptor selective prostaglandin agonists and a prostamide Invest. Ophthalmol. Vis. Sci. 44 2003 4419 4426
44. 2 receptor J. Ocul. Pharmacol. Ther. 11 1995 447 454