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Volumn 33, Issue , 2005, Pages 103-120

Consequences of growth hormone deficiency for intermediary metabolism and effects of replacement

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HUMAN GROWTH HORMONE; HYPERGLYCEMIC AGENT; MUSCLE PROTEIN; PROTEIN; UREA;

EID: 27744451188     PISSN: 03013073     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (7)

References (104)
  • 1
    • 0015612877 scopus 로고
    • Body composition changes in children receiving growth hormone
    • Collip PJ, Curti V, Thomason M: Body composition changes in children receiving growth hormone. Metabolism, 1973;22:589-595.
    • (1973) Metabolism , vol.22 , pp. 589-595
    • Collip, P.J.1    Curti, V.2    Thomason, M.3
  • 2
    • 0027398458 scopus 로고
    • Increased body fat mass and decreased extracellular fluid volume in adults with growth hormone deficiency
    • Oxf
    • Rosen T, Bosaeus I, Tolli J, Lindstedt G, Bengtsson BA: Increased body fat mass and decreased extracellular fluid volume in adults with growth hormone deficiency. Clin Endocrinol (Oxf) 1993;38:63-71.
    • (1993) Clin Endocrinol , vol.38 , pp. 63-71
    • Rosen, T.1    Bosaeus, I.2    Tolli, J.3    Lindstedt, G.4    Bengtsson, B.A.5
  • 3
    • 0027429860 scopus 로고
    • Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency
    • Fowelin J, Attwall S, Lager I, Bengtsson BA: Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency. Metabolism 1993;42:1443-1447.
    • (1993) Metabolism , vol.42 , pp. 1443-1447
    • Fowelin, J.1    Attwall, S.2    Lager, I.3    Bengtsson, B.A.4
  • 5
    • 0020283613 scopus 로고
    • The effect of growth hormone on glucose metabolism and insulin secretion in man
    • Bratusch-Marrain PR, Smith D, De Fronzo RA: The effect of growth hormone on glucose metabolism and insulin secretion in man. J Clin Endocrinol Metab 1982;55:973-982.
    • (1982) J Clin Endocrinol Metab , vol.55 , pp. 973-982
    • Bratusch-Marrain, P.R.1    Smith, D.2    De Fronzo, R.A.3
  • 6
    • 0019970112 scopus 로고
    • Effects of growth hormone on insulin action in man: Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization
    • Rizza RA, Mandarino LJ, Gerich JE: Effects of growth hormone on insulin action in man: Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization. Diabetes 1982;31:663-669.
    • (1982) Diabetes , vol.31 , pp. 663-669
    • Rizza, R.A.1    Mandarino, L.J.2    Gerich, J.E.3
  • 7
    • 0028206903 scopus 로고
    • Acute growth hormone effects on amino acid and lipid metabolism
    • Copeland KC, Nair KS: Acute growth hormone effects on amino acid and lipid metabolism. J Clin Endocrinol Metab 1994;78:1040-1047.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1040-1047
    • Copeland, K.C.1    Nair, K.S.2
  • 8
    • 0035043918 scopus 로고    scopus 로고
    • Control of growth by the somatropic axis: Growth hormone and the insulin-like growth factors have related and independent roles
    • Butler AA, Le Roith D: Control of growth by the somatropic axis: Growth hormone and the insulin-like growth factors have related and independent roles. Annu Rev Physiol 2001;63:141-164.
    • (2001) Annu Rev Physiol , vol.63 , pp. 141-164
    • Butler, A.A.1    Le Roith, D.2
  • 9
    • 0038121116 scopus 로고    scopus 로고
    • Growth hormone therapy in adults
    • Cummings DE, Merriam GR: Growth hormone therapy in adults. Annu Rev Med 2003;54:513-533.
    • (2003) Annu Rev Med , vol.54 , pp. 513-533
    • Cummings, D.E.1    Merriam, G.R.2
  • 10
    • 0026529796 scopus 로고
    • Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men
    • Hartman ML, Veldhuis JD, Johnson ML, Lee MM, Alberti KG, Samojlik E, Thorner MO: Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men. J Clin Endocrinol Metab 1992;74:757-765.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 757-765
    • Hartman, M.L.1    Veldhuis, J.D.2    Johnson, M.L.3    Lee, M.M.4    Alberti, K.G.5    Samojlik, E.6    Thorner, M.O.7
  • 11
    • 0025973802 scopus 로고
    • Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man
    • Veldhuis JD, Iranmanesh A, Ho KY: Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man. J Clin Endocrinol Metab 1991;72:51-59.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 51-59
    • Veldhuis, J.D.1    Iranmanesh, A.2    Ho, K.Y.3
  • 12
    • 0025330710 scopus 로고
    • Human growth hormone prevents the protein catabolic side effects of prednisone in humans
    • Horber FF, Haymond MW: Human growth hormone prevents the protein catabolic side effects of prednisone in humans. J Clin Invest 1990;86:265-272.
    • (1990) J Clin Invest , vol.86 , pp. 265-272
    • Horber, F.F.1    Haymond, M.W.2
  • 14
    • 0025818655 scopus 로고
    • Growth hormone acutely stimulates forearm muscle protein synthesis in normal humans
    • Fryburg DA, Gelfand RA, Barrett EJ: Growth hormone acutely stimulates forearm muscle protein synthesis in normal humans. Am J Physiol 1991;260:E499-E504.
    • (1991) Am J Physiol , vol.260
    • Fryburg, D.A.1    Gelfand, R.A.2    Barrett, E.J.3
  • 15
    • 0026654408 scopus 로고
    • Growth hormone stimulates skeletal muscle protein synthesis and antagonizes insulin's antiproteolytic action in humans
    • Fryburg DA, Louard RJ, Gerow KE, Gelfand RA, Barrett EJ: Growth hormone stimulates skeletal muscle protein synthesis and antagonizes insulin's antiproteolytic action in humans. Diabetes 1992;41:424-429.
    • (1992) Diabetes , vol.41 , pp. 424-429
    • Fryburg, D.A.1    Louard, R.J.2    Gerow, K.E.3    Gelfand, R.A.4    Barrett, E.J.5
  • 17
    • 0028241267 scopus 로고
    • Growth hormone administration in older adults: Effects on albumin synthesis
    • Zachwieja JJ, Bier DM, Yarasheski KE: Growth hormone administration in older adults: Effects on albumin synthesis. Am J Physiol 1994;266:E840-E844.
    • (1994) Am J Physiol , vol.266
    • Zachwieja, J.J.1    Bier, D.M.2    Yarasheski, K.E.3
  • 24
    • 0022456080 scopus 로고
    • Positive nitrogen balance with human growth hormone and hypocaloric intravenous feeding
    • Manson JM, Wilmore DW: Positive nitrogen balance with human growth hormone and hypocaloric intravenous feeding. Surgery 1986;100:188-197.
    • (1986) Surgery , vol.100 , pp. 188-197
    • Manson, J.M.1    Wilmore, D.W.2
  • 25
    • 0025971718 scopus 로고
    • Growth hormone improves muscle protein metabolism and whole body nitrogen economy in man during a hyponitrogenous diet
    • Lundeberg S, Belfrage M, Wernerman J, von der Decken A, Thunell S, Vinnars E: Growth hormone improves muscle protein metabolism and whole body nitrogen economy in man during a hyponitrogenous diet. Metabolism 1991;40:315-322.
    • (1991) Metabolism , vol.40 , pp. 315-322
    • Lundeberg, S.1    Belfrage, M.2    Wernerman, J.3    Von Der Decken, A.4    Thunell, S.5    Vinnars, E.6
  • 26
    • 0035156823 scopus 로고    scopus 로고
    • The protein-retaining effects of growth hormone during fasting involve inhibition of muscle-protein breakdown
    • Nørrelund H, Nair KS, Jørgensen JOL, Christiansen JS, Møller N: The protein-retaining effects of growth hormone during fasting involve inhibition of muscle-protein breakdown. Diabetes 2001;50:96-104.
    • (2001) Diabetes , vol.50 , pp. 96-104
    • Nørrelund, H.1    Nair, K.S.2    Jørgensen, J.O.L.3    Christiansen, J.S.4    Møller, N.5
  • 27
    • 17844367322 scopus 로고    scopus 로고
    • Continuation of growth hormone (GH) substitution during fasting in GH-deficient patients decreases urea excretion and conserves protein synthesis
    • Nørrelund H, Møller N, Nair KS, Christiansen JS, Jørgensen JOL: Continuation of growth hormone (GH) substitution during fasting in GH-deficient patients decreases urea excretion and conserves protein synthesis. J Clin Endocrinol Metab 2001;86:3120-3129.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3120-3129
    • Nørrelund, H.1    Møller, N.2    Nair, K.S.3    Christiansen, J.S.4    Jørgensen, J.O.L.5
  • 29
    • 0015013919 scopus 로고
    • Metabolic response to human growth hormone during prolonged starvation
    • Felig P, Marliss EB, Cahill GF Jr: Metabolic response to human growth hormone during prolonged starvation. J Clin Invest 1971;50:411-421.
    • (1971) J Clin Invest , vol.50 , pp. 411-421
    • Felig, P.1    Marliss, E.B.2    Cahill Jr., G.F.3
  • 30
    • 0023721904 scopus 로고
    • Treatment of obese, diet-restricted subjects with growth hormone for 11 weeks: Effects on anabolism, lipolysis, and body composition
    • Snyder DK, Clemmons DR, Underwood LE: Treatment of obese, diet-restricted subjects with growth hormone for 11 weeks: Effects on anabolism, lipolysis, and body composition. J Clin Endocrinol Metab 1988;67:54-61.
    • (1988) J Clin Endocrinol Metab , vol.67 , pp. 54-61
    • Snyder, D.K.1    Clemmons, D.R.2    Underwood, L.E.3
  • 31
    • 0023251828 scopus 로고
    • Growth hormone administration conserves lean body mass during dietary restriction in obese subjects
    • Clemmons DR, Snyder DK, Williams R, Underwood LE: Growth hormone administration conserves lean body mass during dietary restriction in obese subjects. J Clin Endocrinol Metab 1987;64:878-883.
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 878-883
    • Clemmons, D.R.1    Snyder, D.K.2    Williams, R.3    Underwood, L.E.4
  • 32
    • 0031825711 scopus 로고    scopus 로고
    • Metabolic effects of biosynthetic growth hormone treatment in severely energy-restricted obese women
    • Tagliaferri M, Scacchi M, Pincelli AI: Metabolic effects of biosynthetic growth hormone treatment in severely energy-restricted obese women. Int J Obes 1998;22:836-841.
    • (1998) Int J Obes , vol.22 , pp. 836-841
    • Tagliaferri, M.1    Scacchi, M.2    Pincelli, A.I.3
  • 33
    • 0034105340 scopus 로고    scopus 로고
    • Effects of growth hormone administration on protein dynamics and substrate metabolism during 4 weeks of dietary restriction in obese women
    • Nørrelund H, Børglum J, Jørgensen JOL, Richelsen B, Møller N, Nair KS, Christiansen JS: Effects of growth hormone administration on protein dynamics and substrate metabolism during 4 weeks of dietary restriction in obese women. Clin Endocrinol 2000;52:305-312.
    • (2000) Clin Endocrinol , vol.52 , pp. 305-312
    • Nørrelund, H.1    Børglum, J.2    Jørgensen, J.O.L.3    Richelsen, B.4    Møller, N.5    Nair, K.S.6    Christiansen, J.S.7
  • 34
    • 0019332540 scopus 로고
    • Substrate activation of phenylalanine hydroxylase
    • Shiman R, Gray DW: Substrate activation of phenylalanine hydroxylase. J Biol Chem 1980;255:4793-4800.
    • (1980) J Biol Chem , vol.255 , pp. 4793-4800
    • Shiman, R.1    Gray, D.W.2
  • 35
    • 0030680947 scopus 로고    scopus 로고
    • Growth hormone prevents prednisolone-induced increase in functional hepatic nitrogen clearance in normal man
    • Wolthers T, Grøfte T, Jørgensen JOL, Vilstrup H: Growth hormone prevents prednisolone-induced increase in functional hepatic nitrogen clearance in normal man. J Hepatol 1997;27:789-795.
    • (1997) J Hepatol , vol.27 , pp. 789-795
    • Wolthers, T.1    Grøfte, T.2    Jørgensen, J.O.L.3    Vilstrup, H.4
  • 37
    • 0037147210 scopus 로고    scopus 로고
    • Myostatin inhibits myoblast differentiation by down-regulating MyoD expression
    • Langley B, Thomas M, Bishop A, Sharma M, Gilmour S, Kambadur R: Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J Biol Chem 2002;277:49831-49840.
    • (2002) J Biol Chem , vol.277 , pp. 49831-49840
    • Langley, B.1    Thomas, M.2    Bishop, A.3    Sharma, M.4    Gilmour, S.5    Kambadur, R.6
  • 39
    • 0016583661 scopus 로고
    • Effect of ketone infusions on amino acid and nitrogen metabolism in man
    • Sherwin RS, Hendler RG, Felig P: Effect of ketone infusions on amino acid and nitrogen metabolism in man. J Clin Invest 1975;55:1382-1390.
    • (1975) J Clin Invest , vol.55 , pp. 1382-1390
    • Sherwin, R.S.1    Hendler, R.G.2    Felig, P.3
  • 40
    • 0023722892 scopus 로고
    • Effect of beta-hydroxybutyrate on whole-body leucine kinetics and fractional mixed skeletal muscle protein synthesis in humans
    • Nair KS, Welle SL, Halliday D, Campbell RG: Effect of beta-hydroxybutyrate on whole-body leucine kinetics and fractional mixed skeletal muscle protein synthesis in humans. J Clin Invest 1988;82:198-205.
    • (1988) J Clin Invest , vol.82 , pp. 198-205
    • Nair, K.S.1    Welle, S.L.2    Halliday, D.3    Campbell, R.G.4
  • 42
    • 0023268159 scopus 로고
    • Inhibition of muscular amino acid release by lipid infusion in man
    • Wicklmayr M, Rett K, Schwiegelsohn B: Inhibition of muscular amino acid release by lipid infusion in man. Eur J Clin Invest 1987;17:301-305.
    • (1987) Eur J Clin Invest , vol.17 , pp. 301-305
    • Wicklmayr, M.1    Rett, K.2    Schwiegelsohn, B.3
  • 43
    • 0022549437 scopus 로고
    • Inverse relationship of leucine flux and oxidation to free fatty acid availability in vivo
    • Tessari P, Nissen SL, Miles JM, Haymond MW: Inverse relationship of leucine flux and oxidation to free fatty acid availability in vivo. J Clin Invest 1986;77:575-581.
    • (1986) J Clin Invest , vol.77 , pp. 575-581
    • Tessari, P.1    Nissen, S.L.2    Miles, J.M.3    Haymond, M.W.4
  • 44
    • 0031034019 scopus 로고    scopus 로고
    • Inhibition of lipolysis stimulates whole body glucose production and disposal in normal postabsorptive subjects
    • Fery F, Plat L, Baleriaux M, Balasse EO: Inhibition of lipolysis stimulates whole body glucose production and disposal in normal postabsorptive subjects. J Clin Endocrinol Metab 1997;82:825-830.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 825-830
    • Fery, F.1    Plat, L.2    Baleriaux, M.3    Balasse, E.O.4
  • 45
    • 0029897538 scopus 로고    scopus 로고
    • Role of fat-derived substrates in the regulation of gluconeogenesis during fasting
    • Fery F, Plat L, Melot C, Balasse EO: Role of fat-derived substrates in the regulation of gluconeogenesis during fasting. Am J Physiol 1996;270:E822-E830.
    • (1996) Am J Physiol , vol.270
    • Fery, F.1    Plat, L.2    Melot, C.3    Balasse, E.O.4
  • 47
    • 0025778606 scopus 로고
    • Mechanism of growth hormone-induced post-prandial carbohydrate intolerance in humans
    • Butler P, Kryshak E, Rizza RA: Mechanism of growth hormone-induced post-prandial carbohydrate intolerance in humans. Am J Physiol 1991;260:E513-E520.
    • (1991) Am J Physiol , vol.260
    • Butler, P.1    Kryshak, E.2    Rizza, R.A.3
  • 49
    • 0028067276 scopus 로고
    • Glucose and fat metabolism in adults with growth hormone deficiency
    • Oxf
    • Salomon F, Cuneo RC, Umpleby AM, Sonksen PH: Glucose and fat metabolism in adults with growth hormone deficiency. Clin Endocrinol (Oxf) 1994;41:315-322.
    • (1994) Clin Endocrinol , vol.41 , pp. 315-322
    • Salomon, F.1    Cuneo, R.C.2    Umpleby, A.M.3    Sonksen, P.H.4
  • 50
    • 0026767143 scopus 로고
    • The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition
    • Oxf
    • Binnerts A, Swart GR, Wilson JH, Hoogerbrugge N, Pols HA, Birkenhager JC, Lamberts SW: The effect of growth hormone administration in growth hormone deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition. Clin Endocrinol (Oxf) 1992;37:79-87.
    • (1992) Clin Endocrinol , vol.37 , pp. 79-87
    • Binnerts, A.1    Swart, G.R.2    Wilson, J.H.3    Hoogerbrugge, N.4    Pols, H.A.5    Birkenhager, J.C.6    Lamberts, S.W.7
  • 51
    • 0026724687 scopus 로고
    • Potent effect of recombinant growth hormone on bone mineral density and body composition in adults with panhypopituitarism
    • Degerblad M, Elgindy N, Hall K, Sjoberg HE, Thoren M: Potent effect of recombinant growth hormone on bone mineral density and body composition in adults with panhypopituitarism. Acta Endocrinol 1992;126:387-393.
    • (1992) Acta Endocrinol , vol.126 , pp. 387-393
    • Degerblad, M.1    Elgindy, N.2    Hall, K.3    Sjoberg, H.E.4    Thoren, M.5
  • 52
    • 0001769251 scopus 로고
    • Beneficial effects of 12 months replacement therapy with recombinant human growth hormone to growth hormone deficient adults
    • Rosen T, Johannsson G, Hallgren P, Caidahl K, Bosaeus I, Bengtsson BA: Beneficial effects of 12 months replacement therapy with recombinant human growth hormone to growth hormone deficient adults. Endocrinol Metab 1994;1:55-66.
    • (1994) Endocrinol Metab , vol.1 , pp. 55-66
    • Rosen, T.1    Johannsson, G.2    Hallgren, P.3    Caidahl, K.4    Bosaeus, I.5    Bengtsson, B.A.6
  • 54
    • 17744365203 scopus 로고    scopus 로고
    • Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: Impact on insulin sensitivity and substrate metabolism
    • Nørrelund H, Vahl N, Juul A, Møller N, Alberti KGMM, Skakkebæk NE, Christiansen JS, Jørgensen JO L: Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: Impact on insulin sensitivity and substrate metabolism. J Clin Endocrinol Metab 2000;85:1912-1917.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1912-1917
    • Nørrelund, H.1    Vahl, N.2    Juul, A.3    Møller, N.4    Alberti, K.5    Skakkebæk, N.E.6    Christiansen, J.S.7    Jørgensen, J.O.L.8
  • 55
    • 0028233730 scopus 로고
    • Fuel metabolism, energy expenditure, and thyroid function in growth hormone-treated obese women: A double-blind placebo-controlled study
    • Jørgensen JOL, Pedersen SB, Børglum J, Møller N, Schmitz O, Christiansen JS, Richelsen B: Fuel metabolism, energy expenditure, and thyroid function in growth hormone-treated obese women: A double-blind placebo-controlled study. Metabolism 1994;43:872-877.
    • (1994) Metabolism , vol.43 , pp. 872-877
    • Jørgensen, J.O.L.1    Pedersen, S.B.2    Børglum, J.3    Møller, N.4    Schmitz, O.5    Christiansen, J.S.6    Richelsen, B.7
  • 56
    • 0031057076 scopus 로고    scopus 로고
    • Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure
    • Johannsson G, Marin P, Lonn L, Ottoson M, Stenlof K, Bjorntop P, Sjostrom L, Bengtsson BA: Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure. J Clin Endocrinol Metab 1997;82:727-734.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 727-734
    • Johannsson, G.1    Marin, P.2    Lonn, L.3    Ottoson, M.4    Stenlof, K.5    Bjorntop, P.6    Sjostrom, L.7    Bengtsson, B.A.8
  • 57
    • 15644364105 scopus 로고    scopus 로고
    • Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure
    • Svensson J, Lonn L, Jansson JO: Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure. J Clin Endocrinol Metab 1998;83:362-369.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 362-369
    • Svensson, J.1    Lonn, L.2    Jansson, J.O.3
  • 58
    • 0017156234 scopus 로고
    • The role of growth hormone and cortisone on glucose and gluconeogenic substrate regulation in fasted hypopituitary children
    • Haymond MW, Karl I, Weldon VV, Pagliari AS: The role of growth hormone and cortisone on glucose and gluconeogenic substrate regulation in fasted hypopituitary children. J Clin Endocrinol Metab 1976;42:846-856.
    • (1976) J Clin Endocrinol Metab , vol.42 , pp. 846-856
    • Haymond, M.W.1    Karl, I.2    Weldon, V.V.3    Pagliari, A.S.4
  • 59
    • 0022389332 scopus 로고
    • Effects of hypopituitarism and growth hormone replacement therapy on the production and utilization of glucose in childhood
    • Bougneres PF, Artavia-Loria E, Ferre P, Chaussain JL, Job JC: Effects of hypopituitarism and growth hormone replacement therapy on the production and utilization of glucose in childhood. J Clin Endocrinol Metab 1985;61:1152-1157.
    • (1985) J Clin Endocrinol Metab , vol.61 , pp. 1152-1157
    • Bougneres, P.F.1    Artavia-Loria, E.2    Ferre, P.3    Chaussain, J.L.4    Job, J.C.5
  • 60
    • 0027143634 scopus 로고
    • Marked effects of sustained low growth hormone (GH) levels on day-to-day fuel metabolism: Studies in GH-deficient patients and healthy untreated subjects
    • Jørgensen JOL, Møller J, Alberti KG, Schmitz O, Christiansen JS, Ørskov H, Møller N: Marked effects of sustained low growth hormone (GH) levels on day-to-day fuel metabolism: Studies in GH-deficient patients and healthy untreated subjects. J Clin Endocrinol Metab 1993;77:1589-1596.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1589-1596
    • Jørgensen, J.O.L.1    Møller, J.2    Alberti, K.G.3    Schmitz, O.4    Christiansen, J.S.5    Ørskov, H.6    Møller, N.7
  • 61
    • 0014822836 scopus 로고
    • Influence of fasting on changes in glucose metabolism induced by growth hormone injection in the normal dog
    • Rathgeb I, Steele R, Winkler B, Altszuler N: Influence of fasting on changes in glucose metabolism induced by growth hormone injection in the normal dog. Diabetes 1970;19:487-491.
    • (1970) Diabetes , vol.19 , pp. 487-491
    • Rathgeb, I.1    Steele, R.2    Winkler, B.3    Altszuler, N.4
  • 62
    • 0024433845 scopus 로고
    • Dietary carbohydrate content determines responsiveness to growth hormone in energy-restricted humans
    • Snyder DK, Clemmons DR, Underwood LE: Dietary carbohydrate content determines responsiveness to growth hormone in energy-restricted humans. J Clin Endocrinol Metab 1989;69:745-752.
    • (1989) J Clin Endocrinol Metab , vol.69 , pp. 745-752
    • Snyder, D.K.1    Clemmons, D.R.2    Underwood, L.E.3
  • 63
    • 0025146127 scopus 로고
    • Anabolic effects of growth hormone in obese diet-restricted subjects are dose-dependent
    • Snyder DK, Underwood LE, Clemmons DR: Anabolic effects of growth hormone in obese diet-restricted subjects are dose-dependent. Am J Clin Nutr 1990;52:431-437.
    • (1990) Am J Clin Nutr , vol.52 , pp. 431-437
    • Snyder, D.K.1    Underwood, L.E.2    Clemmons, D.R.3
  • 64
    • 0020145602 scopus 로고
    • Glucose transport in adipocytes and its control by growth hormone in vivo
    • Schoenle E, Zapf J, Froesch ER: Glucose transport in adipocytes and its control by growth hormone in vivo. Am J Physiol 1982;242:E368-E372.
    • (1982) Am J Physiol , vol.242
    • Schoenle, E.1    Zapf, J.2    Froesch, E.R.3
  • 65
    • 0022625026 scopus 로고
    • Pituitary and recombinant deoxyribonucleic acid-derived human growth hormone alter glucose metabolism in 3T3 adipocytes
    • Schwartz J, Foster CM: Pituitary and recombinant deoxyribonucleic acid-derived human growth hormone alter glucose metabolism in 3T3 adipocytes. J Clin Endocrinol Metab 1986;62:791-794.
    • (1986) J Clin Endocrinol Metab , vol.62 , pp. 791-794
    • Schwartz, J.1    Foster, C.M.2
  • 66
    • 0025367528 scopus 로고
    • Growth hormone requirement for a normal human adipocyte glucose carrier function
    • Schoenle E, Qing QR, Zachmann M: Growth hormone requirement for a normal human adipocyte glucose carrier function. J Clin Endocrinol Metab 1990;70:1674-1677.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1674-1677
    • Schoenle, E.1    Qing, Q.R.2    Zachmann, M.3
  • 67
    • 0023678685 scopus 로고
    • Effects of human growth hormone on insulin-stimulated glucose metabolism in 3T3-F442A adipocytes
    • Foster CM, Hale PM, Jing HW, Schwartz J: Effects of human growth hormone on insulin-stimulated glucose metabolism in 3T3-F442A adipocytes. Endocrinology 1988;123:1082-1088.
    • (1988) Endocrinology , vol.123 , pp. 1082-1088
    • Foster, C.M.1    Hale, P.M.2    Jing, H.W.3    Schwartz, J.4
  • 68
    • 0024466139 scopus 로고
    • Antagonism by growth hormone of insulin sensitive hexose transport in 3T3-F442A adipocytes
    • Silverman MS, Mynarcik DC, Corin RE, Haspel HC, Sonenberg M: Antagonism by growth hormone of insulin sensitive hexose transport in 3T3-F442A adipocytes. Endocrinology 1989;125:2600-2604.
    • (1989) Endocrinology , vol.125 , pp. 2600-2604
    • Silverman, M.S.1    Mynarcik, D.C.2    Corin, R.E.3    Haspel, H.C.4    Sonenberg, M.5
  • 69
    • 0025090016 scopus 로고
    • The inhibition of insulin action and glucose metabolism by porcine growth hormone in porcine adipocytes is not the result of any decrease in insulin binding or insulin receptor kinase activity
    • Magri KA, Adamo M, LeRoith D, Etherton TD: The inhibition of insulin action and glucose metabolism by porcine growth hormone in porcine adipocytes is not the result of any decrease in insulin binding or insulin receptor kinase activity. Biochem J 1990;266:107-113.
    • (1990) Biochem J , vol.266 , pp. 107-113
    • Magri, K.A.1    Adamo, M.2    LeRoith, D.3    Etherton, T.D.4
  • 70
    • 0030740995 scopus 로고    scopus 로고
    • Growth hormone-induced insulin resistance: Role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4
    • Smith TR, Elmendorf JS, David TS, Turinsky J: Growth hormone-induced insulin resistance: Role of the insulin receptor, IRS-1, GLUT-1, and GLUT-4. Am J Physiol 1997;272:E1071-E1079.
    • (1997) Am J Physiol , vol.272
    • Smith, T.R.1    Elmendorf, J.S.2    David, T.S.3    Turinsky, J.4
  • 71
    • 0014146768 scopus 로고
    • Effects of growth hormone on glucose utilization in diaphragm muscle in the absence of increased lipolysis
    • Goodman HM: Effects of growth hormone on glucose utilization in diaphragm muscle in the absence of increased lipolysis. Endocrinology 1967;81:1099-1103.
    • (1967) Endocrinology , vol.81 , pp. 1099-1103
    • Goodman, H.M.1
  • 72
    • 0025752274 scopus 로고
    • Effects of growth hormone on fuel utilization and muscle glycogen synthase activity in normal humans
    • Bak JF, Moller N, Schmitz O: Effects of growth hormone on fuel utilization and muscle glycogen synthase activity in normal humans. Am J Physiol 1991;260:E736-E742.
    • (1991) Am J Physiol , vol.260
    • Bak, J.F.1    Moller, N.2    Schmitz, O.3
  • 73
    • 0032711559 scopus 로고    scopus 로고
    • Acute effect of growth hormone to induce peripheral insulin resistance is independent of FFA and insulin levels in rats
    • Kim JK, Choi CS, Youn JH: Acute effect of growth hormone to induce peripheral insulin resistance is independent of FFA and insulin levels in rats. Am J Physiol 1999;277:E742-E749.
    • (1999) Am J Physiol , vol.277
    • Kim, J.K.1    Choi, C.S.2    Youn, J.H.3
  • 75
    • 0025813218 scopus 로고
    • Characterization of the insulin-antagonistic effect of growth hormone in man
    • Fowelin J, Attvall S, von Schenck H, Smith U, Lager I: Characterization of the insulin-antagonistic effect of growth hormone in man. Diabetologia 1991;34:500-506.
    • (1991) Diabetologia , vol.34 , pp. 500-506
    • Fowelin, J.1    Attvall, S.2    Von Schenck, H.3    Smith, U.4    Lager, I.5
  • 77
    • 0025835909 scopus 로고
    • Effect of free fatty acids on glucose uptake and nonoxidative glycolysis across human forearm tissues in the basal state and during insulin stimulation
    • Yki-Jarvinen H, Puhakainen I, Koivisto VA: Effect of free fatty acids on glucose uptake and nonoxidative glycolysis across human forearm tissues in the basal state and during insulin stimulation. J Clin Endocrinol Metab 1991;72:1268-1277.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 1268-1277
    • Yki-Jarvinen, H.1    Puhakainen, I.2    Koivisto, V.A.3
  • 79
    • 0025949378 scopus 로고
    • Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin dependent diabetes mellitus
    • Vaag A, Skott P, Damsbo P, Gall MA, Richter EA, Beck-Nielsen H: Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin dependent diabetes mellitus. J Clin Invest 1991;88:1282-1290.
    • (1991) J Clin Invest , vol.88 , pp. 1282-1290
    • Vaag, A.1    Skott, P.2    Damsbo, P.3    Gall, M.A.4    Richter, E.A.5    Beck-Nielsen, H.6
  • 81
    • 0032829745 scopus 로고    scopus 로고
    • Overnight lowering of free fatty acids with acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects
    • Santomauro AT, Boden G, Silva MER, Rocha DM, Santos RF, Ursich MJM, Strassmann PG, Wajchenberg BL: Overnight lowering of free fatty acids with acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes 1999;48:1836-1841.
    • (1999) Diabetes , vol.48 , pp. 1836-1841
    • Santomauro, A.T.1    Boden, G.2    Silva, M.E.R.3    Rocha, D.M.4    Santos, R.F.5    Ursich, M.J.M.6    Strassmann, P.G.7    Wajchenberg, B.L.8
  • 82
    • 0035491321 scopus 로고    scopus 로고
    • Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure
    • Nielsen S, Møller N, Christiansen JS, Jørgensen JO: Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure. Diabetes 2001;50:2301-2308.
    • (2001) Diabetes , vol.50 , pp. 2301-2308
    • Nielsen, S.1    Møller, N.2    Christiansen, J.S.3    Jørgensen, J.O.4
  • 83
    • 0035218344 scopus 로고    scopus 로고
    • Inhibition of the rise in FFA by acipimox partially prevents GH-induced insulin resistance in GH-deficient adults
    • Segerlantz M, Bramnert M, Manhem P, Laurila E, Groop LC: Inhibition of the rise in FFA by acipimox partially prevents GH-induced insulin resistance in GH-deficient adults. J Clin Endocrinol Metab 2001;86:5813-5818.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5813-5818
    • Segerlantz, M.1    Bramnert, M.2    Manhem, P.3    Laurila, E.4    Groop, L.C.5
  • 84
    • 3242719566 scopus 로고    scopus 로고
    • Modulation of basal glucose metabolism and insulin sensitivity by growth hormone and free fatty acids during short-term fasting
    • Nørrelund H, Nielsen S, Christiansen JS, Jørgensen JOL, Møller N: Modulation of basal glucose metabolism and insulin sensitivity by growth hormone and free fatty acids during short-term fasting. Eur J Endocrinol 2004;150:779-787.
    • (2004) Eur J Endocrinol , vol.150 , pp. 779-787
    • Nørrelund, H.1    Nielsen, S.2    Christiansen, J.S.3    Jørgensen, J.O.L.4    Møller, N.5
  • 85
    • 0026527113 scopus 로고
    • Dose-response studies on the metabolic effects of a growth hormone pulse in humans
    • Møller N, Schmitz O, Møller J, Pørksen N, Jørgensen JOL: Dose-response studies on the metabolic effects of a growth hormone pulse in humans. Metabolism 1992;41:172-175.
    • (1992) Metabolism , vol.41 , pp. 172-175
    • Møller, N.1    Schmitz, O.2    Møller, J.3    Pørksen, N.4    Jørgensen, J.O.L.5
  • 86
    • 0023913827 scopus 로고
    • Nocturnal regulation of free fatty acids in healthy young and elderly men
    • Rosenthal MJ, Woodside WF: Nocturnal regulation of free fatty acids in healthy young and elderly men. Metabolism 1988;37:645-648.
    • (1988) Metabolism , vol.37 , pp. 645-648
    • Rosenthal, M.J.1    Woodside, W.F.2
  • 88
    • 0025100794 scopus 로고
    • Evening versus morning injections of growth hormone (GH) in GH-deficient patients: Effects on 24-hour patterns of circulating hormones and metabolites
    • Jørgensen JOL, Møller N, Lauritzen T, Alberti KG, Ørskov H, Christiansen JS: Evening versus morning injections of growth hormone (GH) in GH-deficient patients: Effects on 24-hour patterns of circulating hormones and metabolites. J Clin Endocrinol Metab 1990;70:207-214.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 207-214
    • Jørgensen, J.O.L.1    Møller, N.2    Lauritzen, T.3    Alberti, K.G.4    Ørskov, H.5    Christiansen, J.S.6
  • 89
    • 0024854194 scopus 로고
    • The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
    • Salomon F, Cuneo RC, Hesp R, Sonksen PH: The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 1989;321:1797-1803.
    • (1989) N Engl J Med , vol.321 , pp. 1797-1803
    • Salomon, F.1    Cuneo, R.C.2    Hesp, R.3    Sonksen, P.H.4
  • 91
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • Reaven G: Role of insulin resistance in human disease. Diabetes 1988;37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.1
  • 92
    • 0025333249 scopus 로고
    • Premature mortality due to cardiovascular disease in hypopituitarism
    • Rosen T, Bengtsson BA: Premature mortality due to cardiovascular disease in hypopituitarism. Lancet 1990;336:285-288.
    • (1990) Lancet , vol.336 , pp. 285-288
    • Rosen, T.1    Bengtsson, B.A.2
  • 93
    • 0026484137 scopus 로고
    • Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults
    • Markussis V, Beshyah SA, Fisher C, Sharp PS, Nicolaides A, Johnston DG: Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults. Lancet 1992;340:1188-1192.
    • (1992) Lancet , vol.340 , pp. 1188-1192
    • Markussis, V.1    Beshyah, S.A.2    Fisher, C.3    Sharp, P.S.4    Nicolaides, A.5    Johnston, D.G.6
  • 94
    • 0025677464 scopus 로고
    • Acute changes in plasma non-esterified fatty acid concentration do not change hepatic glucose production in people with type 2 diabetes
    • Johnston P, Hollenbeck C, Sheu W, Chen Y-D. I, Reaven G: Acute changes in plasma non-esterified fatty acid concentration do not change hepatic glucose production in people with type 2 diabetes. Diabet Med 1990;7:871-875.
    • (1990) Diabet Med , vol.7 , pp. 871-875
    • Johnston, P.1    Hollenbeck, C.2    Sheu, W.3    Chen, Y.-D.I.4    Reaven, G.5
  • 95
    • 0028154380 scopus 로고
    • Growth hormone treatment of obese women for 5 wk: Effect on body composition and adipose tissue LPL activity
    • Richelsen B, Pedersen SB, Børglum J: Growth hormone treatment of obese women for 5 wk: Effect on body composition and adipose tissue LPL activity. Am J Physiol 1994;266:E211-E216.
    • (1994) Am J Physiol , vol.266
    • Richelsen, B.1    Pedersen, S.B.2    Børglum, J.3
  • 96
    • 0027477523 scopus 로고
    • Evidence for increased sensitivity of fuel mobilization to growth hormone during short-term fasting in humans
    • Møller N, Pørksen N, Ovesen P, Alberti KG: Evidence for increased sensitivity of fuel mobilization to growth hormone during short-term fasting in humans. Horm Metab Res 1993;25:175-179.
    • (1993) Horm Metab Res , vol.25 , pp. 175-179
    • Møller, N.1    Pørksen, N.2    Ovesen, P.3    Alberti, K.G.4
  • 98
    • 0034235093 scopus 로고    scopus 로고
    • Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients
    • Richelsen B, Pedersen SB, Kristensen K, Børglum JD, Nørrelund H, Christiansen JS, Jørgensen JOL: Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients. Metabolism 2000;49:906-911.
    • (2000) Metabolism , vol.49 , pp. 906-911
    • Richelsen, B.1    Pedersen, S.B.2    Kristensen, K.3    Børglum, J.D.4    Nørrelund, H.5    Christiansen, J.S.6    Jørgensen, J.O.L.7
  • 99
    • 0016723614 scopus 로고
    • Human pituitary growth hormone. Intrinsic lipolytic activity on rabbit fat cells
    • Lee V, Ramachandran J, Li CH: Human pituitary growth hormone. Intrinsic lipolytic activity on rabbit fat cells. Arch Biochem Biophys 1975;169:669-677.
    • (1975) Arch Biochem Biophys , vol.169 , pp. 669-677
    • Lee, V.1    Ramachandran, J.2    Li, C.H.3
  • 100
    • 0019415546 scopus 로고
    • Separation of early and late responses of adipose tissue to growth hormone
    • Goodman HM: Separation of early and late responses of adipose tissue to growth hormone. Endocrinology 1981;109:120-129.
    • (1981) Endocrinology , vol.109 , pp. 120-129
    • Goodman, H.M.1
  • 101
    • 0021711198 scopus 로고
    • A comparison of the growth promoting, lipolytic, diabetogenic and immunological properties of pituitary and recombinant-DNA-derived bovine growth hormone (somatotropin)
    • Hart IC, Chadwick PM, Boone TC, Langley KE, Rudman C, Souza LM: A comparison of the growth promoting, lipolytic, diabetogenic and immunological properties of pituitary and recombinant-DNA-derived bovine growth hormone (somatotropin). Biochem J 1984;224:93-100.
    • (1984) Biochem J , vol.224 , pp. 93-100
    • Hart, I.C.1    Chadwick, P.M.2    Boone, T.C.3    Langley, K.E.4    Rudman, C.5    Souza, L.M.6
  • 102
    • 0024322191 scopus 로고
    • Different growth hormone-receptor interactions mediate insulin-like and lipolytic responses of rat adipose tissue
    • Chipkin SR, Szecowka J, Tai LR, Kostyo JL, Goodman HM: Different growth hormone-receptor interactions mediate insulin-like and lipolytic responses of rat adipose tissue. Endocrinology 1989;125:450-458.
    • (1989) Endocrinology , vol.125 , pp. 450-458
    • Chipkin, S.R.1    Szecowka, J.2    Tai, L.R.3    Kostyo, J.L.4    Goodman, H.M.5
  • 103
    • 50549202600 scopus 로고
    • The glucose-fatty acid cycle, its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA: The glucose-fatty acid cycle, its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet, 1963;i:785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 104
    • 0027445831 scopus 로고
    • Growth hormone acutely stimulates skeletal muscle but not whole-body protein synthesis in humans
    • Fryburg DA Barrett EJ: Growth hormone acutely stimulates skeletal muscle but not whole-body protein synthesis in humans. Metabolism 1993;42:1223-1227.
    • (1993) Metabolism , vol.42 , pp. 1223-1227
    • Fryburg, D.A.1    Barrett, E.J.2


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