CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway

Acta Pharmacologica Sinica

Volumn 26, Issue 11, 2005, Pages 1309-1316

  Zhang, Tian Tai ^a   Cui, Bing ^a   Dai, De Zai ^a   Su, Wei ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

CPU 86017; Endothelin 1; Hypertension; Monocrotaline; Nitric oxide synthase; Pulmonary artery; Reactive oxygen species

Indexed keywords

4 CHLOROBENZYLTETRAHYDROBERBERINE; BERBERINE DERIVATIVE; CALCIUM ION; CPU 86017; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; INDUCIBLE NITRIC OXIDE SYNTHASE; MALONALDEHYDE; MESSENGER RNA; MONOCROTALINE; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHLORIDE; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTERY TONE; ARTICLE; BLOOD PRESSURE; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; HEART RIGHT VENTRICLE PRESSURE; HEART WEIGHT; HEMODYNAMICS; LUNG PARENCHYMA; LUNG WEIGHT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERUM; VASOCONSTRICTION;

ANIMALS; BERBERINE; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; ENDOTHELIN-1; HYPERTENSION, PULMONARY; LUNG; MALE; MONOCROTALINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; VASOCONSTRICTION;

EID: 27744447851     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2005.00214.x     Document Type: Article

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