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Volumn 6, Issue 11, 2005, Pages 2014-2022

Recombinant production of human microsomal cytochrome P450 2D6 in the methylotrophic yeast Pichia pastoris

(7) Dietrich, Matthias a Grundmann, Lisa a Kurr, Katja a Valinotto, Laura a Saussele, Tanja b Schmid, Rolf D a Lange, Stefan a

a UNIVERSITY OF STUTTGART (Germany)

b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY (Germany)

Author keywords

Ab initio calculations; Activity; Cytochromes; Oxidoreductases; Pichia pastoris; Xenobiotics

Indexed keywords

7 ETHOXYCOUMARIN; ALCOHOL OXIDASE; COMPLEMENTARY DNA; CYTOCHROME P450 2D6; DEXTROMETHORPHAN; HOLOENZYME; METHANOL; PARATHION; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ARTICLE; CIRCULAR DICHROISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ENGINEERING; ENZYME INDUCTION; ENZYME ISOLATION; ENZYME KINETICS; ENZYME SUBSTRATE; ENZYME SYNTHESIS; FUNGAL STRAIN; LIVER MICROSOME METABOLISM; PHASE TRANSITION; PICHIA PASTORIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; XENOBIOTIC METABOLISM;

CYTOCHROME P-450 CYP2D6; HUMANS; METHANOL; METHYLOBACTERIUM; MICROSOMES; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PICHIA; RECOMBINANT PROTEINS;

PICHIA PASTORIS;

EID: 27744441015 PISSN: 14394227 EISSN: None Source Type: Journal
DOI: 10.1002/cbic.200500200 Document Type: Article

Times cited : (35)

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