메뉴 건너뛰기




Volumn 26, Issue SUPPL.2, 1997, Pages 81-85

Simulation of human xenobiotic metabolism in microorganisms: Yeast a good compromise between E. coli and human cells

Author keywords

Drug; Metabolism, Metabolism in microorganisms; Xenobiotics

Indexed keywords

CYTOCHROME P450; XENOBIOTIC AGENT;

EID: 1242334120     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0168-8278(97)80500-4     Document Type: Article
Times cited : (8)

References (19)
  • 2
    • 10144234646 scopus 로고
    • Heterologous expression of mammalian P450 enzymes
    • Waterman MR. Heterologous expression of mammalian P450 enzymes. Adv Enzymol Mol Biol 1993; 17: 37-66.
    • (1993) Adv Enzymol Mol Biol , vol.17 , pp. 37-66
    • Waterman, M.R.1
  • 3
    • 1542491248 scopus 로고
    • Recombinant DNA approaches for the development of metabolic systems used in in vitro toxicology
    • Langenbach R, Smith PB, Crespi C. Recombinant DNA approaches for the development of metabolic systems used in in vitro toxicology. Mutation Res 1992; 277: 251-75.
    • (1992) Mutation Res , vol.277 , pp. 251-275
    • Langenbach, R.1    Smith, P.B.2    Crespi, C.3
  • 6
    • 0026336750 scopus 로고
    • Expression of mammalian cytochrome P450 enzymes using yeast-based vectors
    • Guengerich FR Brian WR, Sari MA, Ross JT. Expression of mammalian cytochrome P450 enzymes using yeast-based vectors. Methods Enzymol 1991; 206: 130-45.
    • (1991) Methods Enzymol , vol.206 , pp. 130-145
    • Guengerich, F.R.1    Brian, W.R.2    Sari, M.A.3    Ross, J.T.4
  • 9
    • 0025994649 scopus 로고
    • Expression and enzymatic activity of recombinant cytochrome P450 17a-hydroxylase in Escherichia coli
    • Barnes HJ, Arlotto MP, Waterman MR. Expression and enzymatic activity of recombinant cytochrome P450 17a-hydroxylase in Escherichia coli. Proc Natl Acad Sci USA 1991; 88: 5597-601.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5597-5601
    • Barnes, H.J.1    Arlotto, M.P.2    Waterman, M.R.3
  • 10
    • 10144226249 scopus 로고
    • The use of bacteria for cytochrome P450 expression
    • Waterman MR, Hildebrand M, eds. Berlin: Springer-Verlag
    • Waterman MR. The use of bacteria for cytochrome P450 expression. In: Waterman MR, Hildebrand M, eds. Assessment of the use of single cytochrome P450 enzymes in drug research. Berlin: Springer-Verlag, 1994; 81-95.
    • (1994) Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research , pp. 81-95
    • Waterman, M.R.1
  • 11
    • 0026324032 scopus 로고
    • Expression of mammalian cytochrome P450 using vaccinia virus
    • Gonzalez FJ, Aoyama T, Gelboin HV. Expression of mammalian cytochrome P450 using vaccinia virus. Methods Enzymol 1991; 206: 85-92.
    • (1991) Methods Enzymol , vol.206 , pp. 85-92
    • Gonzalez, F.J.1    Aoyama, T.2    Gelboin, H.V.3
  • 12
    • 10144259194 scopus 로고
    • Strategies for the use of single cytochrome P450 enzymes in drug research and future prospects
    • Waterman MR, Hildebrand M, eds. Berlin: SpringerVerlag
    • Doehmer J. Strategies for the use of single cytochrome P450 enzymes in drug research and future prospects. In: Waterman MR, Hildebrand M, eds. Assessment of the use of single cytochrome P450 enzymes in drug research. Berlin: SpringerVerlag, 1994; 213-23.
    • (1994) Assessment of the Use of Single Cytochrome P450 Enzymes in Drug Research , pp. 213-223
    • Doehmer, J.1
  • 13
    • 0026319299 scopus 로고
    • Expression of cytochrome P450 cDNAs in human B lymphoblastoid cells, applications to toxicology and metabolite analysis
    • Crespi C. Expression of cytochrome P450 cDNAs in human B lymphoblastoid cells, applications to toxicology and metabolite analysis. Methods Enzymol 1991; 206: 123-9.
    • (1991) Methods Enzymol , vol.206 , pp. 123-129
    • Crespi, C.1
  • 14
    • 0021993827 scopus 로고
    • A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus
    • Sugden B, Marsh K, Yates J. A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus. Mol Cell Biol 1985; 5: 410-3.
    • (1985) Mol Cell Biol , vol.5 , pp. 410-413
    • Sugden, B.1    Marsh, K.2    Yates, J.3
  • 15
    • 85047694578 scopus 로고
    • cDNA cloning and functional expression in yeast Saccharomyces cerevisia of β-naphthoflavone-induced rabbit liver P450 LM4 and LM6
    • Pompon D. cDNA cloning and functional expression in yeast Saccharomyces cerevisia of β-naphthoflavone-induced rabbit liver P450 LM4 and LM6. Eur J Biochem 1987; 177: 285-93.
    • (1987) Eur J Biochem , vol.177 , pp. 285-293
    • Pompon, D.1
  • 16
    • 0027480346 scopus 로고
    • Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-cytochrome P450 reductase and human cytochrome b5
    • Truan G, Cullin C, Reisdorf P, Urban P, Pompon D. Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-cytochrome P450 reductase and human cytochrome b5. Gene 1993; 125: 49-55.
    • (1993) Gene , vol.125 , pp. 49-55
    • Truan, G.1    Cullin, C.2    Reisdorf, P.3    Urban, P.4    Pompon, D.5
  • 17
    • 0027742081 scopus 로고
    • Xenobiotic metabolism in humanized yeast: Engineered yeast cells producing human NADPH-cytochrome P450 reductase, cytochrome b5, epoxide hydrolase and P450s
    • Urban P, Truan G, Gautier JC, Pompon D. Xenobiotic metabolism in humanized yeast: engineered yeast cells producing human NADPH-cytochrome P450 reductase, cytochrome b5, epoxide hydrolase and P450s. Biochem Soc Transac 1993; 21: 1028-33.
    • (1993) Biochem Soc Transac , vol.21 , pp. 1028-1033
    • Urban, P.1    Truan, G.2    Gautier, J.C.3    Pompon, D.4
  • 18
    • 0027339015 scopus 로고
    • Engineered yeast cells as model to study coupling between human xenobiotic metabolizing enzymes: Simulation of the two first steps of benzo[a]pyrene activation
    • Gautier JC, Urban P, Beaune PH, Pompon D. Engineered yeast cells as model to study coupling between human xenobiotic metabolizing enzymes: simulation of the two first steps of benzo[a]pyrene activation. Eur J Biochem 1993; 211: 63-72.
    • (1993) Eur J Biochem , vol.211 , pp. 63-72
    • Gautier, J.C.1    Urban, P.2    Beaune, P.H.3    Pompon, D.4
  • 19
    • 0029964690 scopus 로고    scopus 로고
    • Simulation of human benzo(a)pyrene metabolism deduced from the analysis of individual kinetic steps in recombinant yeast
    • Gautier JC, Urban P, Beaune PH, Pompon D. Simulation of human benzo(a)pyrene metabolism deduced from the analysis of individual kinetic steps in recombinant yeast. Chem Res Toxicol 1996; 9: 418-25.
    • (1996) Chem Res Toxicol , vol.9 , pp. 418-425
    • Gautier, J.C.1    Urban, P.2    Beaune, P.H.3    Pompon, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.