Relationship of bone morphogenetic protein expression during osteoblast differentiation to wild type p53

Journal of Orthopaedic Research

Volumn 23, Issue 6, 2005, Pages 1345-1353

  Chandar, Nalini ^a   Swindle, John ^a   Szajkovics, Ann ^a   Kolman, Kevin ^a  

^a MIDWESTERN UNIVERSITY   (United States)

Author keywords

Bone morphogenetic proteins; Osteoblast differentiation; p53

Indexed keywords

ASCORBIC ACID; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 3A; BONE MORPHOGENETIC PROTEIN 3B; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 8A; BONE MORPHOGENETIC PROTEIN 8B; GLYCEROPHOSPHATE; MUTANT PROTEIN; OSTEOGENIC PROTEIN 1; OSTEOGENIN; PROCOLLAGEN C PROTEINASE; PROTEIN P53; RIBONUCLEASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MATRIX; BONE MINERAL; CANCER CELL CULTURE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; WILD TYPE;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; OSTEOBLASTS; OSTEOCALCIN; OSTEOSARCOMA; PROMOTER REGIONS (GENETICS); RATS; RNA, MESSENGER; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 27644592501     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.orthres.2005.04.010     Document Type: Article

References (40)

1. M. Ahrens et al. Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages DNA Cell Biol 12 1993 871-880
2. R. Aloni-Grinstein I. Zan-Bar I. Alboum N. Goldfinger V. Rotter Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage Oncogene 8 1993 3297-3305
3. J. Armstrong M. Kaufman D. Harrison A. Clarke High-frequency developmental abnormalities in p-53 deficient mice Current Biol 5 1995 931-936
4. S. Bates K. Vousden p53 in signaling checkpoint arrest or apoptosis Curr Opin Genet Devel 6 1996 12-19
5. R. Bendori D. Resnitzky A. Kimchi Changes in p53 mRNA expression during terminal differentiation of murine erythroleukemia cells Virology 161 1987 607-611
6. N. Chandar B. Billig J. McMaster J. Novak Inactivation of p53 gene in human and murine osteosarcoma cells Brit J Cancer 65 1992 208-214
7. N. Chandar P. Campbell J. Novak M. Smith Dependence of induction of osteocalcin gene expression on the presence of wild-type p53 in a murine osteosarcoma cell line Mol Carcinogen 8 1993 299-305
8. N. Chandar L. Donehower N. Lanciloti Reduction in p53 dosage diminishes differentiation capacity of osteoblasts Anticancer Res 20 2000 2555-2562
9. D. Chen et al. Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts Calcif Tissue Int 60 1997 283-290
10. T.J. Cho L.C. Gerstenfeld T.A. Einhorn Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing J Bone Miner Res 17 2002 513-520
11. J. Choi L.A. Donehower p53 in embryonic development: Maintaining a fine balance Cell Mol Life Sci 55 1999 38-47
12. C.Y. Chung et al. Serial passage of MC3T3-E1 cells alters osteoblastic function and responsiveness to transforming growth factor-beta1 and bone morphogenetic protein-2 Biochem Biophys Res Commun 265 1999 246-251
13. L. Diller et al. p53 functions as a cell cycle control protein in osteosarcomas Mol Cell Biol 10 1990 5772-5781
14. S. Ebara K. Nakayama Mechanism for the action of bone morphogenetic proteins and regulation of their activity Spine 27 16 Suppl. 1 2002 S10-S15
15. D. Eliyahu S. Evans et al. p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells Breast Cancer Res Treat 30 1994 167-177
16. D. Eliyahu D. Michalovitz et al. Wild-type p53 can inhibit oncogene-mediated focus formation Proc Natl Acad Sci USA 86 1989 8763-8767
17. N. Ghosh-Choudhury M.A. Harris J.Q. Feng G.R. Mundy S.E. Harris Expression of the BMP 2 gene during bone cell differentiation Crit Rev Eukaryot Gene Exp 4 1999 345-355
18. N. Ghosh-Choudhury M.A. Harris J. Wozney G.R. Mundy S.E. Harris Clonal osteoblastic cell lines from p53 null mouse calvariae are immortalized and dependent on bone morphogenetic protein 2 for mature osteoblastic phenotype Biochem Biophys Res Commun 231 1997 196-202
19. O. Halevy p53 gene is up-regulated during skeletal muscle cell differentiation Biochem Biophys Res Commun 192 1993 714-719
20. S.E. Harris et al. Expression of bone morphogenetic protein messenger RNA in prolonged cultures of fetal rat calvarial cells J Bone Miner Res 9 1994 389-394
21. J. Hino H. Matsuo K. Kangawa Bone morphogenetic protein-3b (BMP-3b) gene expression is correlated with differentiation in rat calvarial osteoblasts Biochem Biophys Res Commun 256 1999 419-424
22. M.H. Lee et al. Transient upregulation of Cbfa1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation J Cell Biochem 73 1999 114-125
23. E. Liscia et al. Terminal differentiation in a non-small-cell bronchopulmonary carcinoma correlates with increased expression of p53 Anticancer Res 16 1996 1209-1212
24. H. Masuda C. Miller H.P. Koeffler H. Battifora M. Cline Rearrangement of the p53 gene in human osteogenic sarcoma Proc Natl Acad Sci USA 84 1987 7716-7719
25. D. Michalovitz O. Halevy et al. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53 Cell 62 1990 671-680
26. C.W. Miller A. Aslo C. Tsay D. Slamon K. Ishizaki J. Toguchida et al. Frequency and structure of p53 arrangements in human osteosarcoma Cancer Res 50 1990 7950-7954
27. I. Morimoto Y. Sasaki et al. Identification of the osteopontin gene as a direct target of TP53 Genes Chromosomes Cancer 33 2002 270-278
28. N.A. Morrison J. Shine et al. 1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene Science 246 1989 1158-1161
29. K. Ohyama C.-H. Chung E. Chen C.W. Gibson K. Misof P. Fratzl et al. p53 Influences mice skeletal development J Craniofac Genet Dev Biol 17 1997 161-171
30. T. Onishi et al. Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats Bone 22 1998 605-612
31. M. Oren Decision making by p53: Life, death and cancer Cell Death Differ 10 2003 431-442
32. V.P. Sah et al. A subset of p53-deficient embryos exhibit exencephaly Nat Genet 10 1995 175-180
33. K.A. Schwartz A.L. Campione M.K. Moore N. Chandar P53 transactivity during osteoblast differentiation Mol Carcinogen 25 1999 132-138
34. C. Shui T.C. Spelsberg B.L. Riggs S. Khosla Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells J Bone Miner Res 18 2003 213
35. S. Soddu G. Blandino G. Citro et al. Wild type p53 gene expression induces granulocytic differentiation of HL-60 cells Blood 83 1994 2230-2237
36. S. Sudhakar Y. Li M.S. Katz N. Elango Translational regulation is a control point in RUNX2/Cbfa1 gene expression Biochem Biophys Res Commun 289 2001 616-622
37. K. Tsuji Y. Ito M. Noda Expression of the PEBP2alphaA/AML3/Cbfa1 gene is regulated by BMP4/7 heterodimer and its overexpression suppresses type I collagen and osteocalcin gene expression in osteoblastic and nonosteoblastic mesenchymal cells Bone 22 1998 87-92
38. S.D. Tyner S. Venkatachalam J. Choi S. Jones N. Ghebranious H. Igelmann et al. p53 mutant mice that display early ageing-associated phenotypes Nature 415 2002 45-53
39. J.M. Wozney Overview of bone morphogenetic proteins Spine 27 16 Suppl. 1 2002 S2-S8
40. A. Yamaguchi T. Komori T. Suda Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1 Endocr Rev 21 2000 393-411