p53 Transactivity during in vitro osteoblast differentiation in a rat osteosarcoma cell line

Molecular Carcinogenesis

Volumn 25, Issue 2, 1999, Pages 132-138

  Schwartz, Karin A ^a   Lanciloti, Natalie J ^a   Moore, Michael K ^a   Campione, Allan L ^a   Chandar, Nalini ^a  

^a MIDWESTERN UNIVERSITY   (United States)

Author keywords

Bone; Differentiation; Osteocalcin; Osteosarcoma; P53

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; COLECALCIFEROL; HYDROXYUREA; OSTEOCALCIN; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; GENE EXPRESSION; GENETIC TRANSFECTION; NONHUMAN; ONCOGENE; OSTEOBLAST; OSTEOSARCOMA; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL MARKERS; CELL CYCLE; CELL DIFFERENTIATION; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CHOLECALCIFEROL; GENES, P53; HYDROXYUREA; OSTEOBLASTS; OSTEOCALCIN; OSTEOSARCOMA; RATS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; UP-REGULATION;

ANIMALIA;

EID: 0032991451     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199906)25:2<132::AID-MC8>3.0.CO;2-2     Document Type: Article

References (24)

1. Diller I, Kassel J, Nelson CE, et al. p53 functions as a cell cycle control protein in osteosarcomas. Mol Cell Biol 1993;13:1415-1423.
2. Yin Y, Tainsky MA, Bischoff FZ, Strong IC, Wahl GM. Wild type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 1992;70:937-948.
3. Dulic V, Kaufmann WK, Wilson SJ, et al. p53 dependent inhibition of cyclin dependent kinase activities in human fibroblasts during radiation induced G1 arrest. Cell 1994;76: 1013-1023.
4. Kern SE, Pietenpol JA, Thiagalingam S, et al. Oncogenic forms of p53 inhibit p53 regulated gene expression. Science 1992; 256:829-830.
5. Kastan MB, Zhan Q, El-Deiry WS, Carrier F, Jacks T, Tlsty TD. Altered cell cycle arrest and gene amplification potential accompany loss of wild type p53. Cell 1992;70:923-935.
6. Masuda H, Miller C, Koeffler HP, Battifora H, Cline M. Rearrangement of the p53 gene in human osteogenic sarcoma. Proc Natl Acad Sci USA 1987;84:7716-7719.
7. Miller CW, Aslo A, Tsay C, et al. Frequency and structure of p53 rearrangements in human osteosarcoma. Cancer Res 1990; 50:7950-7954.
8. Chandar N, Billig B, McMaster J, Novak J. Inactivation of p53 gene in human and murine osteosarcoma cells. Br J Cancer 1992;65:208-214.
9. Chandar N, Campbell P, Novak J, Smith M. Dependence of induction of osteocalcin gene expression on the presence of wild-type p53 in a murine osteosarcoma cell line. Mol Carcinog 1993;8:299-305.
10. Chandar N, McMaster JH, Novak JF. Site specific alterations of the p53 gene in osteosarcomas. In: McMaster JH, Novak JF, editors. Frontiers in osteosarcoma research. Kirkland, WA: Hogrefe and Huber Publishers; 1993. p 431-436.
11. Aloni-Grinstein R, Zan-Bar I, Alboum I, Goldfinger N, Rotter V. Wild type p53 functions as a control protein in the differentiation pathway of the B-cell lineage. Oncogene 1993;8:3297-3305.
12. Soddu S, Blandino G, Citro G, et al. Wild type p53 gene expression induces granulocytic differentiation of HL-60 cells. Blood 1994;83:2230-2237.
13. Almog N, Rotter V. Involvement of p53 in cell differentiation and development. Biochem Biophys Acta 1997;1333:F1-F27.
14. Aronow MA, Gerstenfeld IC, Owen TA, Tassinari MS, Stein GS, Lian JB. Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells. J Cell Physiol 1990;143:213-221.
15. Dworetzky SI, Fey EG, Penman S, Lian JB, Stein JL, Stein GS. Progressive changes in protein composition of the nuclear matrix during rat osteoblast differentiation. Proc Natl Acad Sci USA 1990;87:4605-4609.
16. Stein GS, Lian GB. Molecular mechanisms mediating proliferation-differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr Rev 1993;14: 424-442.
17. Gottlieb TM, Oren M. p53 in growth control and neoplasia. Biochem Biophys Acta 1996;1287:77-102.
18. Kockx M, McCabe I, Stein JL. Influence of DNA replication inhibition on expression of cell growth and tissue specific genes in osteoblasts. J Cell Biochem 1994;54:47-55.
19. Eliyahu D, Michalovitz D, Eliyahu S, et al. Wild type p53 can inhibit oncogene mediated focus formation. Proc Natl Acad Science USA 1989;86:8763-8767.
20. Isfort RJ, Cody DB, Lovell G, Doersen CJ. Comparable oncogene and tumor suppressor gene alterations in rat and human osteosarcomas. Abstract. Proceedings of the American Association for Cancer Research 1992;33:111.
21. Young MF, Kerr JM, Ibaraki K, Heegaard AM, Robey PG. Structure, expression, and regulation of the major noncollagenous matrix proteins of bone. Clin Orthop 1992;281:275-294.
22. Ducy P, Desbois C, Boyce B, et al. Increased bone formation in osteocalcin deficient mice. Nature 1996;382:448-452.
23. Ghosh-Chowdury N, Harris ME, Mundy GR, Harris SE. Transcriptional activation of BMP-2 gene by p53. J Bone Miner Res 1994;9:s138.
24. Buckbinder I, Talbott R, Velasco-Miguel S, Takenaka I, Faha B, Seizinger BR, Kley N. Induction of the growth inhibitor IGF-binding protein-3 by p53. Nature 1995;377:646-649.