RKTS-33, an epoxycyclohexenone derivative that specifically inhibits Fas ligand-dependent apoptosis in CTL-mediated cytotoxicity

Bioscience, Biotechnology and Biochemistry

Volumn 69, Issue 10, 2005, Pages 1923-1928

  Mitsui, Tomokazu ^a   Miyake, Yasunobu ^a,b   Kakeya, Hideaki ^b   Hayashi, Yujiro ^c   Osada, Hiroyuki ^b   Kataoka, Takao ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b Japan Science and Technology Agency   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

(2R,3R,4S) 2,3 epoxy 4 hydroxy 5 hydroxymethyl 6 (1E) propenyl cyclohex 5 en 1 one (ECH); (2R,3R,4S) 2,3 epoxy 4 hydroxy 5 hydroxymethyl cyclohex 5 en 1 one (RKTS 33); Apoptosis; Cytotoxic T lymphocyte (CTL); Fas ligand

Indexed keywords

CELL CULTURE; CYTOLOGY; ENZYME INHIBITION; MOLECULAR STRUCTURE; SYNTHESIS (CHEMICAL); VIRUSES;

APOPTOSIS; CYTOTOXIC T LYMPHOCYTE (CTL); FAS LIGAND;

DERIVATIVES;

CYCLOHEXANONE DERIVATIVE; DNA FRAGMENT; EPOXIDE; FAS LIGAND; FASL PROTEIN, MOUSE; MEMBRANE PROTEIN; PERFORIN; PORE FORMING CYTOTOXIC PROTEIN; TUMOR NECROSIS FACTOR;

ANIMAL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL GRANULE; CELL LINE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DRUG EFFECT; EXOCYTOSIS; IMMUNOLOGY; MOUSE; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CYCLOHEXANONES; CYTOPLASMIC GRANULES; CYTOTOXICITY, IMMUNOLOGIC; DNA FRAGMENTATION; EPOXY COMPOUNDS; EXOCYTOSIS; FAS LIGAND PROTEIN; MEMBRANE GLYCOPROTEINS; MICE; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TUMOR NECROSIS FACTORS;

EID: 27644443160     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.69.1923     Document Type: Article

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