Aspergillus pulmonary infections in transplant recipients

Clinics in Chest Medicine

Volumn 26, Issue 4, 2005, Pages 661-674

  White, Dorothy A ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; AMPHOTERICIN B; ANTIFUNGAL AGENT; CASPOFUNGIN; CYCLOSPORIN A; ECHINOCANDIN; FLUCONAZOLE; GRANULOCYTE COLONY STIMULATING FACTOR; INFLIXIMAB; ITRACONAZOLE; PIPERACILLIN PLUS TAZOBACTAM; POSACONAZOLE; RAPAMYCIN; RECOMBINANT GAMMA INTERFERON; TACROLIMUS; VORICONAZOLE;

ARTICLE; ASPERGILLOSIS; ASPERGILLUS; BRONCHITIS; BRONCHOSPASM; CLINICAL TRIAL; DIAGNOSTIC TEST; DISEASE EXACERBATION; FUNGAL VIRULENCE; FUNGUS CULTURE; GASTROINTESTINAL TOXICITY; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; HOST RESISTANCE; HUMAN; INFECTION COMPLICATION; INFECTION PREVENTION; LOBECTOMY; LUNG INFECTION; LUNG LAVAGE; NAUSEA; NEPHROTOXICITY; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RECIPIENT; SALVAGE THERAPY; SYMPTOMATOLOGY; VOMITING;

EID: 27644433148     PISSN: 02725231     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccm.2005.06.007     Document Type: Review

References (124)

1. N. Singh, and D.L. Paterson Aspergillus infections in transplant recipients Clin Micro Rev 44 2005 1 56
2. R.M. Kotloff, V.N. Ahya, and S.W. Crawford Pulmonary complications of solid organ and hematopoietic stem cell transplantation Am J Respir Crit Care Med 170 2004 22 78
3. A. Wald, W. Leisenring, and J.A. van Burik Epidemiology of Aspergillus infections in a large cohort of patients undergoing bone marrow transplantation J Infect Dis 175 1997 1459 1466
4. T.M. Fukuda, M. Boeckh, and R.A. Carter Risks and outcomes of invasive fungal infections in recipients of allogeneic hematopoietic stem cell transplants after non myeloablative conditioning Blood 102 2003 827 833
5. J.R. Wingard, S.U. Beals, and G.W. Santos Aspergillus infection in bone marrow transplant recipients Bone Marrow Transplant 2 1987 175 180
6. K.A. Marr, R.A. Carter, and F. Crippa Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients Clin Infect Dis 34 2002 909 917
7. A. Wald, W. Leisenring, and J.A. van Burik Epidemiology of Aspergillus infections in a large cohort of patients undergoing bone marrow transplantation J Infect Dis 175 1997 1459 1466
8. N. Singh, N.M. Wagener, and I.R. Marino Trends in invasive fungal infections in liver transplant recipients: correlation with evolution in transplantation practices Transplantation 73 2002 63 67
9. D.L. Paterson, and N. Singh Invasive aspergillosis in transplant recipients Medicine 78 1999 123 138
10. P. Munoz, L. Alcala, and M. Sanchez Conde The isolation of Aspergillus fumigatus from respiratory tract specimens in heart transplant recipients is highly predictive of invasive aspergillosis Transplantation 75 2003 326 329
11. B. Mehrad, G. Paciocco, and F.J. Martinez Spectrum of Aspergillus infection in lung transplant recipients: case series and review of the literature Chest 119 2001 169 175
12. G.E. Westney, S. Kesten, and A. De Hoyos Aspergillus infection in single and double lung transplant recipients Transplantation 61 1996 915 919
13. J.P. Fortun, P. Martin-Davila, and S. Moreno Risk factors for invasive aspergillosis in liver transplant recipients Liver Transplant 8 2002 1065 1070
14. J.W. Baddley, T.P. Stroud, and D. Salzman Invasive mold infections in allogeneic bone marrow transplant recipients Clin Infect Dis 32 2001 1319 1324
15. A. Schaffner, H. Douglas, and A. Braud Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus: observations on these two lines of defense in vitro with human and mouse phagocytes J Clin Invest 69 1982 617 631
16. E. Roilides, A. Dimitriadou-Georgiadou, and T. Sein Tumor necrosis factor alpha enhances antifungal activities of polymorphonuclear and mononuclear phagocytes against Aspergillus fumigatus Infect Immun 66 1998 5999 6003
17. A.R. Waldorf, S. Levitz, and R.D. Diamond In vivo bronchoalveolar macrophage defense against Rhizopus oryzae and Aspergillus fumigatus J Infect Dis 150 1984 752 760
18. M.S. Lionakis, and D.A. Kontoyiannis Glucocorticoids and invasive fungal infections Lancet 362 2003 1828 1838
19. E. Cenci, A. Mencacci, and A. Bacci T cell vaccination in mice with invasive pulmonary aspergillosis J Immunol 165 2000 381 388
20. E. Cenci, A. Mencacci, and G. Del Sero Interleukin-4 causes susceptibility to invasive pulmonary aspergillosis through suppression of protective type I responses J Infect Dis 180 1999 1957 1968
21. K.V. Clemons, G. Grunig, and A. Sobel Role of IL-10 in invasive aspergillosis: increased resistance of IL-10 gene knockout mice to lethal systemic aspergillosis Clin Exp Immunol 122 2000 186 191
22. B. Mehrad, R.M. Striete, and T.J. Standiford Role of TNF-α in pulmonary host defense in murine invasive aspergillosis J Immunol 162 1999 1633 1640
23. J. Parkin, and B. Cohen An overview of the immune system Lancet 357 2001 1777 1789
24. E. Roilides, A. Dimitriadou, and I. Kadiltsoglou IL-10 exerts suppressive and enhancing effects on antifungal activity of mononuclear phagocytes against Aspergillus fumigatus J Immunol 158 1997 322 329
25. M.G. Netea, A. Warris, and W.M. Van der Meer Aspergillus fumigatus evades immune recognition during germination through loss of Toll-like receptor-4-mediated signal transduction J Infect Dis 188 2003 320 326
26. K.A. Marr, R.A. Carter, and M. Boeckh Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors Blood 00 2002 4358 4366
27. W.I. Bensinger Blood or marrow? Lancet 355 2000 1199 1200
28. D. Nachbaur, F.M. Fink, and W. Nussbaumer CD34 + -selected autologous peripheral blood stem cell transplantation (PBSCT) in patients with poor-risk hematological malignancies and solid tumors. A single-centre experience Bone Marrow Transplant 20 1997 827 834
29. M.R. O'Donnell, G.M. Schmidt, and B.R. Tegtmeier Prediction of systemic fungal infection in allogeneic marrow recipients: impact of amphotericin prophylaxis in high-risk patients J Clin Oncol 12 1994 827 834
30. F.M. Marty, S.J. Lee, and E.P. Alyes Infliximab use in patients with severe graft-versus-host disease and other emerging risk factors of non-Candida invasive fungal infections in allogeneic hematopoietic stem cell transplant recipients: a cohort study Blood 102 2003 2768 2776
31. N. Singh, and J. Heitman Antifungal attributes of immunosuppressive agents: new paradigms in management and elucidating the pathophysiologic basis of opportunistic mycoses in organ transplant recipients Transplantation 77 2004 795 800
32. K.P. High, and R.G. Washburn Invasive aspergillosis in mice immunosuppressed with cyclosporin A, tacrolimus (FK506), or sirolimus (rapamycin) J Infect Dis 175 1997 222 225
33. N. Singh, and S. Husain Aspergillus infections after lung transplantation: clinical differences in type of transplant and implications for management J Heart Lung Transplant 21 2003 258 266
34. D.H. Hadjiliadis, D.N. Howell, and R.D. Davis Anastomotic infections in lung transplant recipients Ann Transplant 3 2000 13 19
35. R.N. Husni, S.M. Gordon, and D.L. Longworth Cytomegalovirus infection is a risk factor for invasive aspergillosis in lung transplant recipients Clin Infect Dis 26 1998 753 755
36. P.A. Flume, T.M. Egan, and L.J. Paradowski Infectious complications of lung transplantation. Impact of cystic fibrosis Am J Respir Crit Care Med 149 1994 1601 1607
37. B.C. Cahill, J.R. Hibbs, and K. Savik Aspergillus airway colonization and invasive disease after lung transplantation Chest 112 1997 1160 1164
38. P. Grossi, C. Farina, and R. Fiocchi Prevalence and outcome of invasive fungal infections in 1,963 thoracic organ transplant recipients Transplantation 70 2000 112 116
39. R. Lenner, M.L. Padilla, and A.S. Teirstein Pulmonary complications in cardiac transplant recipients Chest 120 2001 508 513
40. J.M. Cisneros, P. Munoz, J. Torre-Cisneros Spanish Transplantation Infection Study Group Pneumonia after heart transplantation: a multi-institutional study Clin Infect Dis 27 1998 324 331
41. P. Munoz, C. Rodriguez, and E. Bouza Risk factors of invasive aspergillosis after heart transplantation: protective role of oral itraconazole prophylaxis Am J Transplant 4 2004 636 643
42. N. Singh, P.M. Arnow, and A. Bonham Invasive aspergillosis in liver transplant recipients in the 1990s Transplantation 64 1997 716 720
43. J. Torre-Cisneros, O.L. Lopez, and S. Kusne CNS aspergillosis in organ transplantation: a clinicopathologic study J Neurol Neurosurg Psychiatr 56 1993 188 193
44. C.A. Bonham, E.A. Dominguez, and M.B. Fukui Central nervous system lesions in liver transplant recipients: prospective assessment of indications for biopsy and implications for management Transplantation 66 1998 1596 1604
45. N. Singh, R.K. Avery, and P. Munoz Trends in risk profiles for and mortality associated with invasive aspergillosis among liver transplant recipients Clin Infect Dis 36 2003 46 52
46. S. Husain, J. Tollemar, and E.A. Dominguez Changes in the spectrum and risk factors for invasive candidiasis in liver transplant recipients: prospective, multicenter, case-controlled study Transplantation 75 2003 2023 2029
47. M.R. Altiparmak, S. Apaydin, and S. Trablus Systemic fungal infections after renal transplantation Scand J Infect Dis. 34 2002 284 288
48. H.A. Gallis, R.A. Berman, and T.R. Cate Fungal infection following renal transplantation Arch Intern Med 135 1975 1163 1172
49. T.L. Gustafson, W. Schaffner, and G.B. Lavely Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy J Infect Dis 148 1983 230 238
50. A.A. Panackal, A. Dahlman, and K.T. Keil Outbreak of invasive aspergillosis among renal transplant recipients Transplantation 15 2003 1050 1053
51. E. Jantunen, P. Ruutu, and L. Niskanen Incidence and risk factors for invasive fungal infections in allogeneic BMT recipients Bone Marrow Transplant 19 1997 801 808
52. E. Jantunen, A. Piilonen, and L. Volin Diagnostic aspects of invasive Aspergillus infections in allogeneic BMT recipients Bone Marrow Transplant 25 2000 867 871
53. M.J. Kim, K.S. Lee, and J. Kim Crescent sign in invasive pulmonary aspergillosis: frequency and related CT and clinical factors J Comput Assist Tomogr 25 2001 305 310
54. D. Caillot, O. Casasnovas, and A. Bernard Improved management of invasive pulmonary aspergillosis in neutropenic patients using early thoracic computed tomographic scan and surgery J Clin Oncol 15 1997 139 147
55. D.W. Hines, M.H. Haber, and L. Yaremko Pseudomenbranous tracheobronchitis caused by Aspergillus Am Rev Respir Dis 143 1991 1408 1411
56. C.A. Kemper, J.S. Hostetler, and S.E. Follansbee Ulcerative and plaque-like tracheobronchitis due to infection with Aspergillus in patients with AIDS Clin Infect Dis 17 1993 344 352
57. M.R. Kramer, D.W. Denning, and S.E. Marshall Ulcerative tracheobronchitis after lung transplantation: a new form of invasive aspergillosis Am Rev Respir Dis 144 3 pt 1 1991 552 556
58. R. Kessler, G. Massard, and A. Warter Bronchial-pulmonary artery fistula after unilateral lung transplantation: a case report J Heart Lung Transplant 16 1997 674 677
59. B.M. Sterman Sinus surgery in bone marrow transplantation patients Am J Rhinol 13 1999 315 317
60. P. Iwen, E. Reed, and J.O. Armitage Nosocomial invasive aspergillosis in lymphoma patients treated with bone or peripheral stem cell transplants Infect Control Hosp Epidemiol 14 1993 131 139
61. S. Ascioglu, J.H. Rex, and B. de Pauw Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus Clin Infect Dis 34 2002 7 14
62. J.A. Horvath, and S. Dummer The use of respiratory tract cultures in the diagnosis of invasive pulmonary aspergillosis Am J Med 100 1996 171 178
63. H.D. Levy, D.A. Horak, and B.R. Tegtmeier The value of bronchoalveolar lavage and bronchial washings in the diagnosis of invasive pulmonary aspergillosis Respir Med 86 1992 243 248
64. S.W. Crawford, R.C. Hackman, and J.G. Clark Biopsy diagnosis and clinical outcome of persistent focal pulmonary lesions after marrow transplantation Transplantation 48 1989 266 271
65. E. Jantunen, A. Piilonen, and L. Violin Radiologically guided fine needle lung biopsies in the evaluation of focal pulmonary lesions in allogeneic stem cell transplant recipients Bone Marrow Transplant 29 2002 353 356
66. J. Maertens, J. Verhaegen, and K. Lagrou Screening for circulating galactomannan as a non invasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation; a prospective validation Blood 97 2001 1604 1610
67. J. Maertens, J. Verhaegen, and K. Lagrou Use of circulating galactomannan screening for early diagnosis of invasive aspergillosis in allogeneic stem cell transplant recipients J Infect Dis 186 2002 1297 1306
68. J.J. Maertens, J. Verhaegan, and H. Demuynck Autopsy-controlled prospective evaluation of serial screening for circulating galactomannan by a sandwich enzyme-linked immunosorbent assay for hematological patients at risk for invasive Aspergillosis J Clin Microbiol 37 1999 3223 3228
69. A. Sulahian, F. Boutboul, and P. Ribaud Value of antigen detection using an enzyme immunoassay in the diagnosis and prediction of invasive aspergillosis in two adult an pediatric hematology units during a 4-year prospective study Cancer 91 2001 311 318
70. R. Herbrecht, V. Letscher-Bru, and C. Oprea Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patients J Clin Oncol 20 2002 1898 1906
71. C. Pinel, H. Fricker-Hidalgo, and B. Lebeau Detection of circulating Aspergillus fumigatus galactomannan; value and limits of the Platelia test for diagnosing invasive aspergillosis J Clin Microbiol 41 2003 2184 2186
72. R.B. Ferns, H. Fletcher, and S. Bradley The prospective evaluation of a nested polymerase chain reaction assay for the early detection of Aspergillus infection in patients with leukemia or undergoing allograft treatment Br J Haematol 119 2002 720 725
73. S. Husain, E. Kwak, and A. Obman Prospective assessment of Platelia Aspergillus galactomannan antigen for the diagnosis of invasive aspergillosis in lung transplant recipients Am J Transplant 4 2004 796 802
74. J. Fortun, P. Martin-Davila, and M.E. Alvarez Aspergillus antigenemia sandwich enzyme immunoassay test as a serodiagnostic method for invasive aspergillosis in liver transplant recipients Transplantation 71 2001 145 149
75. E. Kwak, S. Husain, and A. Obman Efficacy of galactomannan antigen using Platelia Aspergillus enzyme immunoassay for the diagnosis of invasive aspergillosis in liver transplant recipients J Clin Microbiol 42 2004 435 438
76. B. Musher, D. Fredricks, and W. Leisenring Aspergillus galactomannan enzyme immunoassay and quantitative PCR for diagnosis of invasive aspergillosis with bronchoalveolar fluid J Clin Microbiol 42 2004 5517 5522
77. M.J. Becker, E.J. Lugtenburg, and J.J. Cornelissen Galactomannan detection in computerized tomography-based broncho-alveolar lavage fluid and serum in hematological patients at risk for invasive pulmonary aspergillosis Br J Haematol 121 2003 448 457
78. D. Buchheidt, C. Baust, and H. Skladny Detection of Aspergillus species in blood and bronchoalveolar lavage samples from immunocompromised patients by means of 2-step polymerase chain reaction: clinical results Clin Infect Dis 33 2001 428 435
79. M. Sanguinetti, B. Posteraro, and L. Pagano Comparison of real-time PCR, conventional PCR, and galactomannan antigen detection by enzyme-linked immunosorbent assay using bronchoalveolar lavage fluid samples from hematology patients for diagnosis of invasive pulmonary aspergillosis J Clin Microbiol 41 2003 3922 3925
80. P.E. Verweij, J.P. Latge, and A.J. Rijs Comparison of antigen detection and PCR assay using bronchoalveolar lavage fluid for diagnosing invasive pulmonary aspergillosis in patients receiving treatment for hematological malignancies J Clin Microbiol 33 1995 3150 3153
81. N. Singh, A. Obman, and S. Husain Reactivity of Platelia Aspergillus galactomannan antigen with piperacillin-tazobactam: clinical implications based on achievable serum concentrations Antimicrob Agents Chemother 48 2004 1989 1992
82. J. Loeffler, K. Kloepfer, and H. Hebart Polymerase chain reaction detection of Aspergillus DNA in experimental models of invasive aspergillosis J Infect Dis 158 2002 1203 1206
83. R. Herbrecht, D.W. Denning, and T.F. Patterson Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis N Engl J Med 347 2002 408 415
84. D.W. Denning, P. Ribaud, and N. Milpied Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis Clin Infect Dis 34 2002 563 571
85. D. Mattei, N. Mordani, and C. Lo Nigro Voriconazole in the management of invasive aspergillosis in two patients with acute myeloid leukemia undergoing stem cell transplantation Bone Marrow Transplant 30 2002 967 970
86. P. Linden, K. Cole, and D. Kramer Invasive aspergillosis in liver transplant recipients: comparison of outcome with amphotericin B lipid complex and conventional amphotericin B therapy Transplantation 67 1999 S232
87. R. Bowden, P. Chandrasekar, and M.H. White A double-blind, randomized, controlled trial of amphotericin B colloidal dispersion versus amphotericin B for treatment of invasive aspergillosis in immunocompromised patients Clin Infect Dis 35 2002 359 366
88. N.A. Kartsonis, A.J. Saah, and J. Lipka Salvage therapy with caspofungin for invasive aspergillosis; results from the caspofungin compassionate use study J Infect 50 2005 196 205
89. J. Maertens, I. Raad, and G. Petrikkos Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapy Clin Infect Dis 39 2004 1563 1571
90. T.B. Aliff, P.G. Maslak, and J.G. Jurcic Refractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin Cancer 97 2003 1025 1032
91. A. Schaffner, and P.G. Frick The effect of ketoconazole on amphotericin B in a model of disseminated aspergillosis J Infect Dis 151 1985 901 910
92. A. Polak Combination therapy of experimental candidiasis, cryptococcosis, aspergillosis and wangiellosis in mice Chemotherapy 33 1987 381 395
93. A. Polak, H.J. Scholer, and M. Wall Combination therapy of experimental candidiasis, cryptococcosis and aspergillosis in mice Chemotherapy 28 1982 461 479
94. J.R. Graybill, R. Bocanegra, and G.M. Gonzalez Combination antifungal therapy of murine aspergillosis: liposomal amphotericin B and micafungin J Antimicrob Chemother 52 2003 656 662
95. S. Perea, G. Gonzalez, and A.W. Fothergill In vitro interaction of caspofungin acetate with voriconazole against clinical isolates of Aspergillus spp Antimicrob Agents Chemother 46 2002 3039 3041
96. D.P.R. Kontoyiannis, R. Hachem, and R.E. Lewis Efficacy and toxicity of caspofungin in combination with liposomal amphotericin B as primary or salvage treatment of invasive aspergillosis in patients with hematologic malignancies Cancer 98 2003 292 299
97. K.A. Marr, M. Boeckh, and R.A. Carter Combination antifungal therapy for invasive aspergillosis Clin Infect Dis 39 2004 797 802
98. G.E. Westney, S. Kesten, and A. De Hoyos Aspergillus infection in single and double lung transplant recipients Transplantation 61 1996 915 919
99. V. Monforte, A. Roman, and J. Gavalda Nebulized amphotericin B prophylaxis for Aspergillus infection in lung transplantation study of risk factors J Heart Lung Transplant 20 2001 1274 1281
100. M.D. Dignani, E.J. Anaissie, and J.P. Hester Treatment of neutropenia-related fungal infections with granulocyte colony-stimulating factor-elicited white blood cell transfusions: a pilot study Leukemia 11 1997 1621 1630
101. L. Catalano, R. Fontane, and N. Scarpato Combined treatment with amphotericin B and granulocyte infusion from G-CSF stimulated donors in an aplastic patient with invasive aspergillosis undergoing bone marrow transplantation Haematologica 82 1997 71 72
102. A. Safdar, G. Rodriquez, and N. Ohmagari The safety of interferon-γ-1b therapy for invasive fungal infections after hematopoietic stem cell transplantation Cancer 103 2005 731 739
103. I. Pidhorecky, J. Urschel, and T. Anderson Resection of invasive pulmonary aspergillosis in immunocompromised patients Ann Surg Oncol 7 2000 312 317
104. D. Gossot, P. Validire, and R. Vaillancourt Full thoracoscopic approach for surgical management of invasive pulmonary aspergillosis Ann Thorac Surg 73 2002 240 244
105. J.M. Habicht, F. Reichenberger, and A. Gratwohl Surgical aspects of resection for suspected invasive pulmonary fungal infection in neutropenic patients Ann Thorac Surg 68 1999 321 325
106. K.W. Gow, A.A. Hayes-Jordan, and C.A. Billups Benefit of surgical resection of invasive pulmonary aspergillosis in pediatric patients undergoing treatment for malignancies and immunodeficiency syndromes J Pediatr Surg 38 2003 1354 1360
107. P. Matt, F. Bernet, and J. Habicht Predicting outcome after lung resection for invasive pulmonary aspergillosis in patients with neutropenia Chest 126 2004 1783 1788
108. J.M. Habicht, P. Matt, and J.R. Passweg Invasive pulmonary fungal infection in hematologic patients; is resection effective? Hematol J 2 2001 250 256
109. S.N. Wolff, J. Fay, and D. Stevens Fluconazole vs. low-dose amphotericin B for the prevention of fungal infections in patients undergoing bone marrow transplantation: a study of the North American Marrow Transplant Group Bone Marrow Transplant 25 2000 853 859
110. S.M. Kelsey, J.M. Goldman, and S. McCann Liposomal amphotericin (AmBisome) in the prophylaxis of fungal infections in neutropenic patients: a randomized, double-blind placebo-controlled study Bone Marrow Transplant 23 1999 163 168
111. E. Conneally, M.T. Cafferkey, and P.A. Daly Nebulized amphotericin B as prophylaxis against invasive aspergillosis in granulocytic patients Bone Marrow Transplant 5 1990 403 406
112. G.F. Behre, S. Schwartz, and K. Lenz Aerosol amphotericin B inhalations for prevention of invasive pulmonary aspergillosis in neutropenic cancer patients Ann Hematol 71 1995 287 291
113. L. Harousseau, A.W. Dekker, and A. Stamatoullas-Bastard Itraconazole oral solution for primary prophylaxis of fungal infections in patients with hematological malignancy and profound neutropenia: a randomized, double-blind, double-placebo multicenter trial comparing itraconazole and amphotericin B Antimicrob Agents Chemother 44 2000 1887 1893
114. G.R. Morgentern, A.G. Prentice, and H.G. Prentice A randomized controlled trial of itraconazole versus fluconazole for the prevention of fungal infections in patients with hematological malignancies Br J Haematol 105 1999 901 911
115. K.A. Marr, F. Crippa, and W. Leisenring Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplants Blood 103 2004 1527 1533
116. A. Imhof, A. Balajee, and D.N. Fredricks Breakthrough fungal infections in stem cell transplant recipients receiving voriconazole Clin Infect Dis 39 2004 743 746
117. J.S. Dummer, N. Lazariashvilli, and J. Barnes A survey of anti-fungal management in lung transplantation J Heart Lung Transpl 23 2004 1376 1381
118. S. Palmer, R.H. Drew, and J.D. Whitehouse Safety of aerosolized amphotericin B lipid complex in lung transplant recipients Transplantation 72 2001 545 548
119. A. Minari, R. Husni, and R.K. Avery The incidence of invasive aspergillosis among solid organ transplant recipients and implications for prophylaxis in lung transplants Transpl Infect Dis 4 2002 195 200
120. R.H. Drew, A. Dodds, and D.K. Benjamin Comparative safety of amphotericin B lipid complex and amphotericin B deoxycholate as aerosolized antifungal prophylaxis in lung-transplant recipients Transplantation 77 2004 232 237
121. J. Hamacher, A. Spiliopoulos, A.-M. Kurt for the Geneva Lung Transplantation Group Pre-emptive therapy with azoles in lung transplant patients Eur Respir J 13 1999 180 186
122. V. Calvo, J.M. Borro, and P. Morales Antifungal prophylaxis during the early postoperative period of lung transplantation Chest 115 1999 1301 1304
123. N. Singh, D.L. Paterson, and T. Gayowski Preemptive prophylaxis with a lipid preparation of amphotericin B for invasive fungal infections in liver transplant recipients requiring replacement therapy Transplantation 71 2001 910 913
124. S. Singhal, R.W. Ellis, and S.G. Jones Targeted prophylaxis with amphotericin B lipid complex in liver transplantation Liver Transplant 6 2000 588 595