Association of angiotensinogen gene polymorphisms with essential hypertension in African-Americans and caucasians

Human Heredity

Volumn 60, Issue 2, 2005, Pages 89-96

  Markovic, Daniela ^a   Tang, Xiagna ^b   Guruju, Mallikarjunrao ^b   Levenstien, Mark A ^a   Hoh, Josephine ^a   Kumar, Ashok ^b   Ott, Jurg ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Angiotensinogen; Hypertension; Polymorphism

Indexed keywords

ANGIOTENSINOGEN;

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; CASE CONTROL STUDY; CAUCASIAN; DNA POLYMORPHISM; ESSENTIAL HYPERTENSION; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PROMOTER REGION;

AFRICAN AMERICANS; AGED; ANGIOTENSINOGEN; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; HUMANS; HYPERTENSION; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS);

EID: 27544480881     PISSN: 00015652     EISSN: None     Source Type: Journal    
DOI: 10.1159/000088657     Document Type: Article

References (44)

1. Ward R: Familial aggregation and genetic epidemiology of blood pressure; in Laragh J, Brenner B (eds): Hypertension: Pathophysiology, Diagnosis, and Management. New York, Raven Press, 1990, pp 81-100.
2. Pickering G: Hyperpiesis: High blood-pressure without evident cause: Essential hypertension. Br Med J 1965;5469:1021-1026 concl.
3. Inagami T: The renin-angiotensin system. Essays Biochem 1994;28:147-164.
4. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, Hunt SC, Hopkins PN, Williams RR, Lalouel JM, et al: Molecular basis of human hypertension: role of angiotensinogen. Cell 1992;71:169-180.
5. Martinez E, Puras A, Escribano J, Sanchis C, Carrion L, Artigao M, Divison JA, Masso J, Fernandez JA: Threonines at position 174 and 235 of the angiotensinogen polypeptide chain are related to familial history of hypertension in a Spanish-Mediterranean population. Br J Biomed Sci 2002;59:95-100.
6. Pan WH, Chen JW, Fann C, Jou YS, Wu SY: Linkage analysis with candidate genes: the Taiwan young-onset hypertension genetic study. Hum Genet 2000;107:210-215.
7. Pereira AC, Mota GF, Cunha RS, Herbenhoff FL, Mill JG, Krieger JE: Angiotensinogen 235T allele 'dosage' is associated with blood pressure phenotypes. Hypertension 2003;41:25-30.
8. Sato N, Katsuya T, Nakagawa T, Ishikawa K, Fu Y, Asai T, Fukuda M, Suzuki F, Nakamura Y, Higaki J, Ogihara T: Nine polymorphisms of angiotensinogen gene in the susceptibility to essential hypertension. Life Sci 2000;68:259-272.
9. Rankinen T, Gagnon J, Perusse L, Chagnon YC, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C: AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study. Am J Physiol Heart Circ Physiol 2000;279:H368-H374.
10. Jeunemaitre X, Inoue I, Williams C, Charru A, Tichet J, Powers M, Sharma AM, Gimenez-Roqueplo AP, Hata A, Corvol P, Lalouel JM: Haplotypes of angiotensinogen in essential hypertension. Am J Hum Genet 1997;60:1448-1460.
11. Iso H, Harada S, Shimamoto T, Sato S, Kitamura A, Sankai T, Tanigawa T, Iida M, Komachi Y: Angiotensinogen T174M and M235T variants, sodium intake and hypertension among non-drinking, lean Japanese men and women. J Hypertens 2000;18:1197-1206.
12. Rotimi C, Morrison L, Cooper R, Oyejide C, Effiong E, Ladipo M, Osotemihen B, Ward R: Angiotensinogen gene in human hypertension. Lack of an association of the 235T allele among African Americans. Hypertension 1994;24:591-594.
13. Province MA, Boerwinkle E, Chakravarti A, Cooper R, Fornage M, Leppert M, Risch N, Ranade K: Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood Institute. J Hypertens 2000;18:867-876.
14. Kato N, Sugiyama T, Morita H, Kurihara H, Furukawa T, Isshiki T, Sato T, Yamori Y, Yazaki Y: Comprehensive analysis of the renin-angiotensin gene polymorphisms with relation to hypertension in the Japanese. J Hypertens 2000;18:1025-1032.
15. Larson N, Hutchinson R, Boerwinkle E: Lack of association of 3 functional gene variants with hypertension in African Americans. Hypertension 2000;35:1297-1300.
16. Caulfield M, Lavender P, Newell-Price J, Kamdar S, Farrall M, Clark AJ: Angiotensinogen in human essential hypertension. Hypertension 1996;28:1123-1125.
17. Caulfield M, Lavender P, Newell-Price J, Farrall M, Kamdar S, Daniel H, Lawson M, De Freitas P, Fogarty P, Clark AJ: Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans. J Clin Invest 1995;96:687-692.
18. Inoue I, Nakajima T, Williams CS, Quackenbush J, Puryear R, Powers M, Cheng T, Ludwig EH, Sharma AM, Hata A, Jeunemaitre X, Lalouel JM: A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997;99:1786-1797.
19. Sethi AA, Nordestgaard BG, Tybjaerg-Hansen A: Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysis. Arterioscler Thromb Vasc Biol 2003;23:1269-1275.
20. Sethi AA, Nordestgaard BG, Gronholdt ML, Steffensen R, Jensen G, Tybjaerg-Hansen A: Angiotensinogen single nucleotide polymorphisms, elevated blood pressure, and risk of cardiovascular disease. Hypertension 2003;41:1202-1211.
21. Zhu X, Chang YP, Yan D, Weder A, Cooper R, Luke A, Kan D, Chakravarti A: Associations between hypertension and genes in the renin-angiotensin system. Hypertension 2003;41:1027-1034.
22. Jain S, Tang X, Narayanan CS, Agarwal Y, Peterson SM, Brown CD, Ott J, Kumar A: Angiotensinogen gene polymorphism at -217 affects basal promoter activity and is associated with hypertension in African-Americans. J Biol Chem 2002;277:36889-36896.
23. Jain S, Li Y, Patil S, Kumar A: A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity. J Mol Med 2005;83:121-131.
24. Wu SJ, Chiang FT, Chen WJ, Liu PH, Hsu KL, Hwang JJ, Lai LP, Lin JL, Tseng CD, Tseng YZ: Three single-nucleotide polymorphisms of the angiotensinogen gene and susceptibility to hypertension: single locus genotype vs. haplotype analysis. Physiol Genomics 2004;17:79-86.
25. Zhao YY, Zhou J, Narayanan CS, Cui Y, Kumar A: Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene. Hypertension 1999;33:108-115.
26. Walker WG, Whelton PK, Saito H, Russell RP, Hermann J: Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ambulatory subjects. Hypertension 1979;1:287-291.
27. Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, Smithies O: Genetic control of blood pressure and the angiotensinogen locus. Proc Natl Acad Sci USA 1995;92:2735-2739.
28. Lewontin R: The interaction of selection and linkage. I. General considerations; heterotic models. Genetics 1964;49:49-67.
29. Benjamini Y, Hochberg Y: Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Roy Stat Soc B 1995;57:289-300.
30. Yanai K, Saito T, Hirota K, Kobayashi H, Murakami K, Fukamizu A: Molecular variation of the human angiotensinogen core promoter element located between the TATA box and transcription initiation site affects its transcriptional activity. J Biol Chem 1997;272:30558-30562.
31. Iwai N, Shimoike H, Ohmichi N, Kinoshita M: Angiotensinogen gene and blood pressure in the Japanese population. Hypertension 1995;25:688-693.
32. Kunz R, Kreutz R, Beige J, Distler A, Sharma AM: Association between the angiotensinogen 235T-variant and essential hypertension in whites: A systematic review and methodological appraisal. Hypertension 1997;30:1331-1337.
33. Hata A, Namikawa C, Sasaki M, Sato K, Nakamura T, Tamura K, Lalouel JM: Angiotensinogen as a risk factor for essential hypertension in Japan. J Clin Invest 1994;93:1285-1287.
34. Kamitani A, Rakugi H, Higaki J, Yi Z, Mikami H, Miki T, Ogihara T: Association analysis of a polymorphism of the angiotensinogen gene with essential hypertension in Japanese. J Hum Hypertens 1994;8:521-524.
35. Nakajima T, Jorde LB, Ishigami T, Umemura S, Emi M, Lalouel JM, Inoue I: Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations. Am J Hum Genet 2002;70:108-123.
36. Lynch KR, Peach MJ: Molecular biology of angiotensinogen. Hypertension 1991;17:263-269.
37. Falkner B: Differences in blacks and whites with essential hypertension: Biochemistry and endocrine. State of the art lecture. Hypertension 1990;15:681-686.
38. Sethi AA, Nordestgaard BG, Agerholm-Larsen B, Frandsen E, Jensen G, Tybjaerg-Hansen A: Angiotensinogen polymorphisms and elevated blood pressure in the general population: The Copenhagen City Heart Study. Hypertension 2001;37:875-881.
39. Fornage M, Turner ST, Sing CF, Boerwinkle E: Variation at the M235T locus of the angiotensinogen gene and essential hypertension: A population-based case-control study from Rochester, Minnesota. Hum Genet 1995;96:295-300.
40. Hegele RA, Brunt JH, Connelly PW: A polymorphism of the angiotensinogen gene associated with variation in blood pressure in a genetic isolate. Circulation 1994;90:2207-2212.
41. Ward K, Hata A, Jeunemaitre X, Helin C, Nelson L, Namikawa C, Farrington PF, Ogasawara M, Suzumori K, Tomoda S, Berrebi S, Sasaki M, Corvol P, Lifton RP, Lalouel JM: A molecular variant of angiotensinogen associated with preeclampsia. Nat Genet 1993;4:59-61.
42. Azizi M, Hallouin MC, Jeunemaitre X, Guyene TT, Menard J: Influence of the M235T polymorphism of human angiotensinogen (AGT) on plasma AGT and renin concentrations after ethinylestradiol administration. J Clin Endocrinol Metab 2000;85:4331-4337.
43. Zhu X, Cooper RS, Chen G, Luke A, Elston RC: Localization of the Q1 mutation by cladistic analysis. Genet Epidemiol 2001;21(suppl 1):S594-599.
44. Darlu P, Genin E: Cladistic analysis of haplotypes as an attempt to detect disease susceptibility. Genet Epidemiol 2001;21(suppl 1):S602-607.