-
1
-
-
0842346436
-
Beginning to understand the end of the chromosome
-
Cech, T. R. (2004) Beginning to understand the end of the chromosome, Cell 116, 273-279.
-
(2004)
Cell
, vol.116
, pp. 273-279
-
-
Cech, T.R.1
-
2
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E. H. (2001) Switching and signaling at the telomere, Cell 106, 661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
3
-
-
0032522443
-
The telomerase reverse transcriptase: Components and regulation
-
Nugent, C. I., and Lundblad, V. (1998) The telomerase reverse transcriptase: Components and regulation, Genes Dev. 12, 1073-1085.
-
(1998)
Genes Dev.
, vol.12
, pp. 1073-1085
-
-
Nugent, C.I.1
Lundblad, V.2
-
4
-
-
0038701907
-
Biochemical aspects of telomerase function
-
Harrington, L. (2003) Biochemical aspects of telomerase function, Cancer Lett. 194, 139-154.
-
(2003)
Cancer Lett.
, vol.194
, pp. 139-154
-
-
Harrington, L.1
-
5
-
-
0030938901
-
Reverse transcriptase motifs in the catalytic subunit of telomerase
-
Lingner, J., Hughes, T. R., Shevchenko, A., Mann, M., Lundblad, V., and Cech, T. R. (1997) Reverse transcriptase motifs in the catalytic subunit of telomerase, Science 276, 561-567.
-
(1997)
Science
, vol.276
, pp. 561-567
-
-
Lingner, J.1
Hughes, T.R.2
Shevchenko, A.3
Mann, M.4
Lundblad, V.5
Cech, T.R.6
-
6
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. (1997) Telomerase catalytic subunit homologs from fission yeast and human, Science 277, 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
7
-
-
0031266239
-
Telomerase is a true reverse transcriptase. A review
-
Cech, T. R., Nakamura, T. M., and Lingner, J. (1997) Telomerase is a true reverse transcriptase. A review, Biochemistry (Moscow) 62, 1202-1205.
-
(1997)
Biochemistry (Moscow)
, vol.62
, pp. 1202-1205
-
-
Cech, T.R.1
Nakamura, T.M.2
Lingner, J.3
-
8
-
-
6944256804
-
An emerging consensus for telomerase RNA structure
-
Chen, J. L., and Greider, C. W. (2004) An emerging consensus for telomerase RNA structure, Proc. Natl. Acad. Sci. U.S.A. 101, 14683-14684.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 14683-14684
-
-
Chen, J.L.1
Greider, C.W.2
-
9
-
-
3042798454
-
Yeast telomerase RNA: A flexible scaffold for protein subunits
-
Zappulla, D. C., and Cech, T. R. (2004) Yeast telomerase RNA: A flexible scaffold for protein subunits, Proc. Natl. Acad. Sci. U.S.A. 101, 10024-10029.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10024-10029
-
-
Zappulla, D.C.1
Cech, T.R.2
-
10
-
-
6944242754
-
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein
-
Lin, J., Ly, H., Hussain, A., Abraham, M., Pearl, S., Tzfati, Y., Parslow, T. G., and Blackburn, E. H. (2004) A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein, Proc. Natl. Acad. Sci. U.S.A. 101, 14713-14718.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 14713-14718
-
-
Lin, J.1
Ly, H.2
Hussain, A.3
Abraham, M.4
Pearl, S.5
Tzfati, Y.6
Parslow, T.G.7
Blackburn, E.H.8
-
11
-
-
3342875215
-
Structural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase
-
Chappell, A. S., and Lundblad, V. (2004) Structural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase, Mol. Cell. Biol. 24, 7720-7736.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7720-7736
-
-
Chappell, A.S.1
Lundblad, V.2
-
12
-
-
3142532677
-
A phylogenetically based secondary structure for the yeast telomerase RNA
-
Dandjinou, A. T., Levesque, N., Larose, S., Lucier, J. F., Abou Elela, S., and Wellinger, R. J. (2004) A phylogenetically based secondary structure for the yeast telomerase RNA, Curr. Biol. 14, 1148-1158.
-
(2004)
Curr. Biol.
, vol.14
, pp. 1148-1158
-
-
Dandjinou, A.T.1
Levesque, N.2
Larose, S.3
Lucier, J.F.4
Abou Elela, S.5
Wellinger, R.J.6
-
13
-
-
0035912746
-
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity
-
Sperger, J. M., and Cech, T. R. (2001) A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity, Biochemistry 40, 7005-7016.
-
(2001)
Biochemistry
, vol.40
, pp. 7005-7016
-
-
Sperger, J.M.1
Cech, T.R.2
-
14
-
-
0033134835
-
Telomerase RNA function in recombinant Tetrahymena telomerase
-
Licht, J. D., and Collins, K. (1999) Telomerase RNA function in recombinant Tetrahymena telomerase, Genes Dev. 13, 1116-1125.
-
(1999)
Genes Dev.
, vol.13
, pp. 1116-1125
-
-
Licht, J.D.1
Collins, K.2
-
15
-
-
0037076276
-
Telomerase recognizes its template by using an adjacent RNA motif
-
Miller, M. C., and Collins, K. (2002) Telomerase recognizes its template by using an adjacent RNA motif, Proc. Natl. Acad. Sci U.S.A. 99, 6585-6590.
-
(2002)
Proc. Natl. Acad. Sci U.S.A.
, vol.99
, pp. 6585-6590
-
-
Miller, M.C.1
Collins, K.2
-
16
-
-
0037083759
-
Template boundary definition in Tetrahymena telomerase
-
Lai, C. K., Miller, M. C., and Collins, K. (2002) Template boundary definition in Tetrahymena telomerase, Genes Dev. 16, 415-420.
-
(2002)
Genes Dev.
, vol.16
, pp. 415-420
-
-
Lai, C.K.1
Miller, M.C.2
Collins, K.3
-
17
-
-
0032004614
-
Mutational analysis of the Tetrahymena telomerase RNA: Identification of residues affecting telomerase activity in vitro
-
Autexier, C., and Greider, C. W. (1998) Mutational analysis of the Tetrahymena telomerase RNA: Identification of residues affecting telomerase activity in vitro, Nucleic Acids Res. 26, 787-795.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 787-795
-
-
Autexier, C.1
Greider, C.W.2
-
18
-
-
0041631045
-
Stem-loop IV of Tetrahymena telomerase RNA stimulates processivity in trans
-
Mason, D. X., Goneska, E., and Greider, C. W. (2003) Stem-loop IV of Tetrahymena telomerase RNA stimulates processivity in trans, Mol. Cell. Biol. 23, 5606-5613.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5606-5613
-
-
Mason, D.X.1
Goneska, E.2
Greider, C.W.3
-
19
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
Greider, C. W., and Blackburn, E. H. (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts, Cell 43, 405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
20
-
-
0032555261
-
The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex
-
Collins, K., and Gandhi, L. (1998) The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex, Proc. Natl. Acad. Sci. U.S.A. 95, 8485-8490.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 8485-8490
-
-
Collins, K.1
Gandhi, L.2
-
21
-
-
0034604578
-
A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity
-
Bryan, T. M., Goodrich, K. J., and Cech, T. R. (2000) A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity, J. Biol. Chem. 275, 24199-24207.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24199-24207
-
-
Bryan, T.M.1
Goodrich, K.J.2
Cech, T.R.3
-
22
-
-
0033535962
-
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
-
Gilley, D., and Blackburn, E. H. (1999) The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein, Proc. Natl. Acad. Sci. U.S.A. 96, 6621-6625.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 6621-6625
-
-
Gilley, D.1
Blackburn, E.H.2
-
23
-
-
0038433298
-
Roles for RNA in telomerase nucleotide and repeat addition processivity
-
Lai, C. K., Miller, M. C., and Collins, K. (2003) Roles for RNA in telomerase nucleotide and repeat addition processivity, Mol. Cell 11, 1673-1683.
-
(2003)
Mol. Cell
, vol.11
, pp. 1673-1683
-
-
Lai, C.K.1
Miller, M.C.2
Collins, K.3
-
24
-
-
0024978857
-
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
-
Greider, C. W., and Blackburn, E. H. (1989) A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis, Nature 337, 331-337.
-
(1989)
Nature
, vol.337
, pp. 331-337
-
-
Greider, C.W.1
Blackburn, E.H.2
-
25
-
-
0032481419
-
A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase
-
Wang, H., Gilley, D., and Blackburn, E. H. (1998) A novel specificity for the primer-template pairing requirement in Tetrahymena telomerase, EMBO J. 17, 1152-1160.
-
(1998)
EMBO J.
, vol.17
, pp. 1152-1160
-
-
Wang, H.1
Gilley, D.2
Blackburn, E.H.3
-
26
-
-
0034664006
-
Template definition by Tetrahymena telomerase reverse transcriptase
-
Miller, M. C., Liu, J. K., and Collins, K. (2000) Template definition by Tetrahymena telomerase reverse transcriptase, EMBO J. 19, 4412-4422.
-
(2000)
EMBO J.
, vol.19
, pp. 4412-4422
-
-
Miller, M.C.1
Liu, J.K.2
Collins, K.3
-
27
-
-
0029128539
-
Boundary elements of the Tetrahymena telomerase RNA template and alignment domains
-
Autexier, C., and Greider, C. W. (1995) Boundary elements of the Tetrahymena telomerase RNA template and alignment domains, Genes Dev. 9, 2227-2239.
-
(1995)
Genes Dev.
, vol.9
, pp. 2227-2239
-
-
Autexier, C.1
Greider, C.W.2
-
28
-
-
0028269621
-
Functional reconstitution of wild-type and mutant Tetrahymena telomerase
-
Autexier, C., and Greider, C. W. (1994) Functional reconstitution of wild-type and mutant Tetrahymena telomerase, Genes Dev. 8, 563-575.
-
(1994)
Genes Dev.
, vol.8
, pp. 563-575
-
-
Autexier, C.1
Greider, C.W.2
-
29
-
-
0029144984
-
Altering specific telomerase RNA template residues affects active site function
-
Gilley, D., Lee, M. S., and Blackburn, E. H. (1995) Altering specific telomerase RNA template residues affects active site function, Genes Dev. 9, 2214-2226.
-
(1995)
Genes Dev.
, vol.9
, pp. 2214-2226
-
-
Gilley, D.1
Lee, M.S.2
Blackburn, E.H.3
-
30
-
-
0034659801
-
Three telomerases with completely non-telomeric template replacements are catalytically active
-
Ware, T. L., Wang, H., and Blackburn, E. H. (2000) Three telomerases with completely non-telomeric template replacements are catalytically active, EMBO J. 19, 3119-3131.
-
(2000)
EMBO J.
, vol.19
, pp. 3119-3131
-
-
Ware, T.L.1
Wang, H.2
Blackburn, E.H.3
-
31
-
-
0347724051
-
Inhibition of telomerase activity by preventing proper assemblage
-
Keppler, B. R., and Jarstfer, M. B. (2004) Inhibition of telomerase activity by preventing proper assemblage, Biochemistry 43, 334-343.
-
(2004)
Biochemistry
, vol.43
, pp. 334-343
-
-
Keppler, B.R.1
Jarstfer, M.B.2
-
33
-
-
0033636319
-
Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase
-
Bryan, T. M., Goodrich, K. J., and Cech, T. R. (2000) Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase, Mol. Cell 6, 493-499.
-
(2000)
Mol. Cell
, vol.6
, pp. 493-499
-
-
Bryan, T.M.1
Goodrich, K.J.2
Cech, T.R.3
-
34
-
-
0029312758
-
Analysis of the structure of Tetrahymena nuclear RNAs in vivo: Telomerase RNA, the self-splicing rRNA intron, and U2 snRNA
-
Zaug, A. J., and Cech, T. R. (1995) Analysis of the structure of Tetrahymena nuclear RNAs in vivo: Telomerase RNA, the self-splicing rRNA intron, and U2 snRNA, RNA 1, 363-374.
-
(1995)
RNA
, vol.1
, pp. 363-374
-
-
Zaug, A.J.1
Cech, T.R.2
-
35
-
-
0026680843
-
Site-specific modification of pre-mRNA: The 2′-hydroxyl groups at the splice sites
-
Moore, M. J., and Sharp, P. A. (1992) Site-specific modification of pre-mRNA: The 2′-hydroxyl groups at the splice sites, Science 256, 992-997.
-
(1992)
Science
, vol.256
, pp. 992-997
-
-
Moore, M.J.1
Sharp, P.A.2
-
36
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
37
-
-
0027275438
-
Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation
-
Collins, K., and Greider, C. W. (1993) Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation, Genes Dev. 7, 1364-1376.
-
(1993)
Genes Dev.
, vol.7
, pp. 1364-1376
-
-
Collins, K.1
Greider, C.W.2
-
38
-
-
4644354584
-
Adding to the ends: What makes telomerase processive and how important is it?
-
Lue, N. F. (2004) Adding to the ends: What makes telomerase processive and how important is it? Bioessays 26, 955-962.
-
(2004)
Bioessays
, vol.26
, pp. 955-962
-
-
Lue, N.F.1
-
39
-
-
0242286004
-
The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity
-
Huard, S., Moriarty, T. J., and Autexier, C. (2003) The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity, Nucleic Acids Res. 31, 4059-4070.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4059-4070
-
-
Huard, S.1
Moriarty, T.J.2
Autexier, C.3
-
40
-
-
0035895954
-
Requirements for the dGTP-dependent repeat addition processivity of recombinant Tetrahymena telomerase
-
Hardy, C. D., Schultz, C. S., and Collins, K. (2001) Requirements for the dGTP-dependent repeat addition processivity of recombinant Tetrahymena telomerase, J. Biol. Chem. 276, 4863-4871.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4863-4871
-
-
Hardy, C.D.1
Schultz, C.S.2
Collins, K.3
-
41
-
-
0028222581
-
The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena
-
Strahl, C., and Blackburn, E. H. (1994) The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena, Nucleic Acids Res. 22, 893-900.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 893-900
-
-
Strahl, C.1
Blackburn, E.H.2
-
42
-
-
0028856541
-
Utilization of ribonucleotides and RNA primers by Tetrahymena telomerase
-
Collins, K., and Greider, C. W. (1995) Utilization of ribonucleotides and RNA primers by Tetrahymena telomerase, EMBO J. 14, 5422-5432.
-
(1995)
EMBO J.
, vol.14
, pp. 5422-5432
-
-
Collins, K.1
Greider, C.W.2
-
43
-
-
3042533374
-
The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro
-
Aigner, S., and Cech, T. R. (2004) The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro, RNA 10, 1108-1118.
-
(2004)
RNA
, vol.10
, pp. 1108-1118
-
-
Aigner, S.1
Cech, T.R.2
-
45
-
-
2342419732
-
DNA replication fidelity
-
Kunkel, T. A. (2004) DNA replication fidelity, J. Biol. Chem. 279, 16895-16898.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16895-16898
-
-
Kunkel, T.A.1
-
46
-
-
0029439048
-
The fidelity of human telomerase
-
Kreiter, M., Irion, V., Ward, J., and Morin, G. (1995) The fidelity of human telomerase, Nucleic Acids Symp. Ser. 137-139.
-
(1995)
Nucleic Acids Symp. Ser.
, pp. 137-139
-
-
Kreiter, M.1
Irion, V.2
Ward, J.3
Morin, G.4
-
47
-
-
0942276311
-
Influences of ribonucleotide on a duplex conformation and its thermal stability: Study with the chimeric RNA-DNA strands
-
Nakano, S., Kanzaki, T., and Sugimoto, N. (2004) Influences of ribonucleotide on a duplex conformation and its thermal stability: Study with the chimeric RNA-DNA strands, J. Am. Chem. Soc. 126, 1088-1095.
-
(2004)
J. Am. Chem. Soc.
, vol.126
, pp. 1088-1095
-
-
Nakano, S.1
Kanzaki, T.2
Sugimoto, N.3
-
48
-
-
0016768294
-
Conformations and structural transitions in polydeoxynucleotides
-
Pilet, J., Blicharski, J., and Brahms, J. (1975) Conformations and structural transitions in polydeoxynucleotides, Biochemistry 14, 1869-1876.
-
(1975)
Biochemistry
, vol.14
, pp. 1869-1876
-
-
Pilet, J.1
Blicharski, J.2
Brahms, J.3
-
49
-
-
0035937262
-
A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC)
-
Stefl, R., Trantirek, L., Vorlickova, M., Koca, J., Sklenar, V., and Kypr, J. (2001) A-like guanine-guanine stacking in the aqueous DNA duplex of d(GGGGCCCC), J. Mol. Biol. 307, 513-524.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 513-524
-
-
Stefl, R.1
Trantirek, L.2
Vorlickova, M.3
Koca, J.4
Sklenar, V.5
Kypr, J.6
-
50
-
-
0023051844
-
1H NMR study of poly(dG)-poly(dC) in solution using one-dimensional nuclear Overhauser effect
-
1H NMR study of poly(dG)-poly(dC) in solution using one-dimensional nuclear Overhauser effect, Biochemistry 25, 3659-3665.
-
(1986)
Biochemistry
, vol.25
, pp. 3659-3665
-
-
Sarma, M.H.1
Gupta, G.2
Sarma, R.H.3
-
51
-
-
0022419269
-
The crystal structure of d(G-G-G-G-C-C-C-C). A model for poly(dG)·poly-(dC)
-
McCall, M., Brown, T., and Kennard, O. (1985) The crystal structure of d(G-G-G-G-C-C-C-C). A model for poly(dG)·poly-(dC), J. Mol. Biol 183, 385-396.
-
(1985)
J. Mol. Biol.
, vol.183
, pp. 385-396
-
-
McCall, M.1
Brown, T.2
Kennard, O.3
-
52
-
-
0022828754
-
CC/GG contacts facilitate the B to A transition of DNA in solution
-
Minchenkova, L. E., Schyolkina, A. K., Chernov, B. K., and Ivanov, V. I. (1986) CC/GG contacts facilitate the B to A transition of DNA in solution, J. Biomol. Struct. Dyn. 4, 463-476.
-
(1986)
J. Biomol. Struct. Dyn.
, vol.4
, pp. 463-476
-
-
Minchenkova, L.E.1
Schyolkina, A.K.2
Chernov, B.K.3
Ivanov, V.I.4
-
55
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang, H., Chopra, R., Verdine, G. L., and Harrison, S. C. (1998) Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance, Science 282, 1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
56
-
-
0032518524
-
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal
-
Kiefer, J. R., Mao, C., Braman, J. C., and Beese, L. S. (1998) Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal, Nature 391, 304-307.
-
(1998)
Nature
, vol.391
, pp. 304-307
-
-
Kiefer, J.R.1
Mao, C.2
Braman, J.C.3
Beese, L.S.4
|