Cadherins and catenins in clival chordomas: Correlation of expression with tumor aggressiveness

American Journal of Surgical Pathology

Volumn 29, Issue 11, 2005, Pages 1422-1434

  Triana, Aymara ^a   Sen, Chandranath ^a   Wolfe, David ^b   Hazan, Rachel ^c  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b MOUNT SINAI HOSPITAL   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Aggressiveness; Cadherin; Catenins; Chordoma; Expression

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CADHERIN; CATENIN; NERVE CELL ADHESION MOLECULE; PLAKOGLOBIN; UVOMORULIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CHORDOMA; CLINICAL ARTICLE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR LOCALIZATION;

ADOLESCENT; ADULT; AGED; CADHERINS; CATENINS; CHORDOMA; CRANIAL FOSSA, POSTERIOR; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; SKULL BASE NEOPLASMS;

EID: 27244456520     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000180447.25141.a4     Document Type: Article

References (70)

1. Aplin AE, Howe A, Alahari SK, et al. Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol Rev. 1998;50:197-263.
2. Al-Mefty O, Borba LA. Skull base chordomas: a management challenge. J Neurosurg. 1997;86:182-189.
3. Becker KF, Kremmer E, Schulz S, et al. Functional allelic loss detected at the protein level in archival human tumors using allele-specific E-cadherin monoclonal antibodies. J Pathol. 2002;197:567-574.
4. Birchmeier W, Behrens J, Weidner KM, et al. Epithelial differentiation and the control of metastasis in carcinomas. Curr Top Microbiol Immunol. 1996;231:117-135.
5. Bixby JL, Zhang R. Purified N-cadherin is a potent substrate for the rapid induction of neurite outgrowth. J Cell Biol. 1990;110:1253-1260.
6. Bracke M, Roy FV, Mareel M. The E-cadherin/catenin complex in invasion and metastasis. Curr Top Microbiol Immunol. 1996;213:123-161.
7. Bridge JA, Pickering D, Neff JR. Cytogenetic and molecular cytogenetic analysis of sacral chordoma. Cancer Genet Cytogenet. 1994;75:23-25.
8. Bryden AA, Hoyland JA, Freemont AJ, et al. E-cadherin and β-catenin are down-regulated in prostatic bone metastases. BJU Int. 2002;89:400-403.
9. Bukholm IK, Nesland JM, Karesen R, et al. E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma. J Pathol. 1998;185:262-266.
10. Buonamici L, Roncaroli F, Fioravanti A, et al. Cytogenetic investigation of chordomas of the skull. Cancer Genet Cytogenet. 1999;112:49-52.
11. Cavallaro U, Schaffhauser B, Christofori G. Cadherins and the tumor progression: is it all in a switch? Cancer Lett. 2002;176:123-128.
12. Crockard HA, Steel T, Plowman N, et al. A multidisciplinary team approach to skull base chordomas. J Neurosurg. 2001;95:184-189.
13. Colli B, Al-Mefty O. Chordomas of the craniocervical junction: follow-up review and prognostic factors. J Neurosurg. 2001;95:933-943.
14. Dalpra L, Malgara R, Miozzo M, et al. First cytogenetic study of a recurrent familial chordoma of the clivus. Int J Cancer. 1999;81:24-30.
15. DeBoer JM, Neff JR, Bridge JA. Cytogenetics of sacral chordoma. Cancer Genet Cytogenet. 1992;64:95-96.
16. De Lise AM, Fischer L, Tuan RS. Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage. 2000;8:309-334.
17. Deniz M, Kilic T, Almaata I, et al. Expression of growth factors and structural proteins in chordomas: basic fibroblast growth factor, transforming growth factor α, and fibronectin are correlated with recurrence. Neurosurgery. 2002;51:753-776.
18. Duband JL, Monier F, Delannet M, et al. Epithelium-mesenchyme transition during neural crest development. Acta Anat (Basel). 1995;154:63-78.
19. Eisenberg MB, Woloschak M, Sen C, et al. Loss of heterozygosity in the retinoblastoma tumor supressor gene in skull base chordomas and chondrosarcomas. Surg Neurol. 1997;47:156-160.
20. Fouquet B, Zimbelmann R, Franke WW. Identification of plakoglobin in oocytes and early embryos of Xenopus laevis: maternal expression of a gene encoding a junctional plaque protein. Differentiation. 1992;51:187-194.
21. Gofuku J, Shiozaki H, Tsujinaka T, et al. Expression of E-cadherin and alpha-catenin in patients with colorectal carcinoma: correlation with cancer invasion and metastasis. Am J Clin Pathol. 1999;111:29-37.
22. Gumbiner BM. Proteins associated with the cytoplasmic surface of adhesion molecules. Neuron. 1993;11:551-564.
23. Hanahan D, Weinberg R. The hallmarks of cancer. Cell. 2000;100:57-70.
24. Hatta K, Takeichi M. Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature. 1986;320:447-449.
25. Hatta K, Takagi S, Fujisawa H, et al. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Dev Biol. 1987;120:215-227.
26. Hazan R, Kang L, Whooley B, et al. N-cadherin promotes adhesion between invasive breast cancer cells and the stroma. Cell Adhes Commun. 1997;4:399-411.
27. Hazan R, Phillips G, Qiao R, et al. Exogenous expression of N-cadherin in breast cancer cell induces cell migration, invasion, and metastasis. J Cell Biol. 2000;148:779-790.
28. Hazan R, Qiao R, Keren R, et al. Cadherin switch in tumor progression. Ann NY Acad Sci. 2004;1014:155-163.
29. Hecht A, Litterst CM, Huber O, et al. Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro. J Biol Chem. 1999;274:18017-18025.
30. Holton J, Steel T, Luxsuwong M, et al. Skull base chordomas: correlation of tumour doubling time with age, mitosis and Ki 67 proliferation index. Neuropathol Appl Neurobiol. 2000;26:497-503.
31. Hsu MY, Wheelock M, Johnson KR, et al. Shifts in cadherin profiles between human normal melanocytes and melanomas. J Invest Dermatol Symp Proc. 1996;1:188-194.
32. Islam S, Carey T, Wolf G, et al. Expression of N-cadherin by human squamous carcinoma cells induced a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J Cell Biol. 1996;135:1643-1654.
33. Kemler R. Classical cadherins. Semin Cell Biol. 1992;3:149-155.
34. Klingler L, Shocks J, Fiedler PN, et al. Microsatellite instability in sacral chordoma. J Surg Oncol. 2000;73:100-103.
35. Knudsen KA, Soler AP, Johson KR, et al. Interaction of alpha-actinin with the N-cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol. 1995;130:67-77.
36. Laskin W, Miettinen M. Epithelial-type and Neural-type cadherin expression in malignant noncarcinomatous neoplasms with epitheliod features that involve the soft tissues. Arch Pathol Lab Med. 2002;126:425-431.
37. Li G, Satyamoorthy K, Herlyn M. N-cadherin mediated intercellular interactions promote survival and migration of melanoma cells. Cancer Res. 2001;61:3819-3825.
38. Liotta L, Steeg P, Stetler-Stevenson W. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell. 1991; 64:327-336.
39. Matsuno A, Sasaki T, Nagashima T, et al. Immunohistochemical examination of proliferative potentials and the expression of cell cycle-related proteins of intracranial chordomas. Hum Pathol. 1997;28:714-719.
40. Menezes AH, Gantz BJ, Traynelis VC, et al. Cranial base chordomas. Clin Neurosurg. 1997;44:491-509.
41. Mori K, Chano T, Kushima R, et al. Expression of E-cadherin in chordomas: diagnostic marker and possible role of tumor cell affinity. Virchows Arch. 2002;440:123-127.
42. Nagafuchi A, Ishihara S, Tskukita S. The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-α- catenin fusion molecules. J Cell Biol. 1994;127:235-245.
43. Nagafuchi A, Takeichi M. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 1988;7:3679-3684.
44. Naka T, Oda Y, Iwamoto Y, et al. Immunohistochemical analysis of E-cadherin, alpha-catenin, beta-catenin and gamma-catenin, and neural adhesion molecule (NCAM) in chordoma. J Clin Pathol. 2001;54:945-950.
45. Naka T, Fukuda T, Chuman H, et al. Proliferative activities in conventional chordoma: a clinicopathologic, DNA flow cytometric, and immunohistochemical analysis of 17 specimens with special reference to anaplastic chordoma showing a diffuse proliferation and nuclear atypia. Hum Pathol. 1996;27:381-388.
46. Nieman MT, Prudoff RS, Johnson KR, et al. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. J Cell Biol. 1999;147:631-634.
47. O'Connell JK, Renard LG, Liebsch NJ, et al. Base of skull chordoma: a correlative study of histologic and clinical features of 62 cases. Cancer. 1994;74:2261-2267.
48. Oberlender SA, Tuan RS. Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development. 1994;120: 177-187.
49. Overduin M, Harvey TS, Bagby S, et al. Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science. 1995;267:386-389.
50. Ozawa M, Ringwald M, Kemler R. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Natl Acad Sci USA. 1990;87:4246-4250.
51. Pallini R, Maira G, Anile C, et al. Chordoma of the skull base: predictors of tumor recurrence. J Neurosurg. 2003;98:812-822.
52. Pertz O, Bozic D, Koch AW, et al. A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation. EMBO J. 1999;18:1738-1747.
53. Redies C, Takeichi M. Expression of N-cadherin mRNA during dvelopment of the mousse brain. Dev Dyn. 1993;197:26-39.
54. Riethmacher D, Brinkmann V, Bierchmeier C. A targeted mutation in the mousse E-cadherin gene results in defective preimplantation development. Proc Natl Acad Sci USA. 1995;92:855-859.
55. Rimm D, Sinard J, Morrow J. Reduced alpha-catenin and E-cadherin expression in breast cancer. Lab Invest. 1995;72:506-512.
56. Sandig M, Voura E, Kalnins Y et al. Role of cadherins in the transendothelial migration of melanoma cells in culture. Cell Motil Cytoskeleton. 1997;38:351-364.
57. Sato H, Hazegawa T, Abe Y, et al. Expression of E-cadherin in bone and soft tissue sarcomas: a possible role in epithelial differentiation. Hum Pathol. 1999;30:1344-1349.
58. Scheil S, Bruderlain S, Liehr T, et al. Genome-wide analysis of 16 chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CHI. Genes Chromosomes Cancer. 2001;32:203-211.
59. Shapiro L, Fannon A, Kwong P, et al. Structural basis of cell-cell adhesion by cadherins. Nature. 1995;374:327-337.
60. Sen C, Triana A. Cranial chordomas: results of radical excision. Available from: Am Assoc of Neurol Surg, VA. Accessed February 15, 2001. Neurosurg Focus. 2001;10:1-7. (serial online)
61. Suyama K, Shapiro I, Guttman M, et al. A signaling pathway leading to metastasis is controlled by the N-cadherin and the FGF receptor. Cancer Cell. 2002;2:301-314.
62. Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science. 1991;251:1451-1455.
63. Takeichi M. Cadherins in cancer: implications for invasion and metastasis. Curr Opin Cell Biol. 1993;5:806-811.
64. Tomita K, van Bokhoven A, van Leenders G, et al. Cadherin switching in human prostate cancer progression. Cancer Res. 2000;60:3650-3654.
65. Tran N, Nagle R, Cress A, et al. N-cadherin expression in human prostate carcinoma cell lines: an epithelial-mesenchymal transformation mediating adhesion with stromal cells. Am J Pathol. 1999;155:787-798.
66. Triana A, Sen C, Patel N, et al. Approaches to the posterior skull base. In: Batjer H, Loftus C, eds. Textbook of Neurological Surgery. Philadelphia: Lippincott Williams & Wilkins, 2001:1423-1438.
67. Viebahn C. Epithelio-mesenchymal transformation during formation of the mesoderm in the mammalian embryo. Acta Anat (Basel). 1995;154: 79-97.
68. Volpe R, Mazabraud A. A clinicopathological review of 25 cases of chordoma (a pleomorphic and metastasizing neoplasm). Am J Surg Pathol. 1983;7:161-170.
69. Watkins L, Khudados ES, Kaleoglu M, et al. Skull base chordomas: a review of 38 patients, 1958-88. Br J Neurosurg. 1993;7:241-248.
70. Wijnhoven BPL, Dinjens WNM, Pignatelli M. E-cadherin-catenin cell-cell adhesion complex and human cancer. Br J Surg. 2000;87:992-1005.