Steroidal and triterpenoidal fungal metabolites as ligands of liver X receptors

Journal of Antibiotics

Volumn 58, Issue 9, 2005, Pages 559-565

  Ondeyka, John G ^a   Jayasuriya, Hiranthi ^a   Herath, Kithsiri B ^a   Guan, Ziqiang ^a   Schulman, Marvin ^a   Collado, Javier ^a   Dombrowski, Anne W ^a   Kwon, Soojin S ^a   McCallum, Christine ^a   Sharma, Neelam ^a   MacNaul, Karen ^a   Hayes, Nancy ^a   Menke, John G ^a   Singh, Sheo B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cholesterol lowering agents; LXR receptor agonists; Microbial products; Steroids; Triterpenoids

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; CHOLESTEROL; CYCLOARTANE DERIVATIVE; CYCLOEUCALENONE; ERGOSTANE DERIVATIVE; ERGOSTEROL; ERGOSTEROL PEROXIDE; HIGH DENSITY LIPOPROTEIN; HYPOCHOLESTEROLEMIC AGENT; LIGAND; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN; STEROID; TRIENONE; TRITERPENOID; UNCLASSIFIED DRUG;

ACANTHAMOEBA POLYPHAGA; ACREMONIUM SORDIDULUM; ARTICLE; BINDING ASSAY; BIOASSAY; CHOLESTEROL METABOLISM; COLLETOTRICHUM DEMATIUM; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; FUNGUS; IC 50; IN VITRO STUDY; LIGAND BINDING; LIVER X RECEPTOR SCINTILLATION PROXIMITY ASSAY; METABOLITE; MONOTROPA UNIFLORA; MUSA SAPIENTUM; NAEGLERIA GRUBERI; NAEGLERIA LOVANIENSIS; NONHUMAN; PLEUROTUS OSTREATUS; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; TOLYPOCLADIUM NIVEUM;

ACANTHAMOEBA POLYPHAGA; ACREMONIUM (ASCOMYCOTA); COLLETOTRICHUM DEMATIUM; FUNGI; MONOTROPA UNIFLORA; MUSA X PARADISIACA; NAEGLERIA GRUBERI; NAEGLERIA LOVANIENSIS; PLEUROTUS OSTREATUS; TOLYPOCLADIUM INFLATUM;

EID: 27244453583     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2005.76     Document Type: Article

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