Massive sequence perturbation of a small protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 42, 2005, Pages 14988-14993

  Campbell Valois, F X ^a   Tarassov, K ^a   Michnick, S W ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Massive mutagenesis; Protein structure topology; Protein fragment complementation assay; Raf ras binding domain; Ubiquitin superfold

Indexed keywords

BINDING PROTEIN; POLYPEPTIDE; PROTEIN; RAF PROTEIN; RAS PROTEIN; UBIQUITIN;

ARTICLE; CIRCULAR DICHROISM; ENTROPY; HYDROPHOBICITY; MUTAGENESIS; PLASMID; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

AMINO ACID SEQUENCE; DATABASES, PROTEIN; ENTROPY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE LIBRARY; PROTEIN CONFORMATION; PROTEIN FOLDING; RAF KINASES; RANDOM ALLOCATION; REPRODUCIBILITY OF RESULTS; SEQUENCE ALIGNMENT;

EID: 27244441819     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500465102     Document Type: Article

References (33)

1. Perutz, M. F., Kendrew, J. C. & Watson, H. C. (1965) J. Mol. Biol. 13, 669-678.
2. Lesk, A. M. & Chothia, C. (1980) J. Mol. Biol. 136, 225-270.
3. Lau, K. F. & Dill, K. A. (1990) Proc. Natl. Acad. Sci. USA 87, 638-642.
4. Bonneau, R., Strauss, C. E. & Baker, D. (2001) Proteins 43, 1-11.
5. Dantas, G., Kuhlman, B., Callender, D., Wong, M. & Baker, D. (2003) J. Mol. Biol. 332, 449-460.
6. Kuhlman, B., Dantas, G., Ireton, G. C., Varani, G., Stoddard, B. L. & Baker, D. (2003) Science 302, 1364-1368.
7. Scalley-Kim, M. & Baker, D. (2004) J. Mol. Biol. 338, 573-583.
8. Arkin, A. P. & Youvan, D. C. (1992) Proc. Natl. Acad. Sci. USA 89, 7811-7815.
9. Reidhaar-Olson, J. F. & Sauer, R. T. (1988) Science 241, 53-57.
10. Lim, W. A. & Sauer, R. T. (1989) Nature 339, 31-36.
11. Axe, D. D., Foster, N. W. & Fersht, A. R. (1996) Proc. Natl. Acad. Sci. USA 93, 5590-5594.
12. Finucane, M. D. & Woolfson, D. N. (1999) Biochemistry 38, 11613-11623.
13. Gu, H., Kim, D. & Baker, D. (1997) J. Mol. Biol. 274, 588-596.
14. Kim, D. E., Gu, H. & Baker, D. (1998) Proc. Natl. Acad. Sci. USA 95, 4982-4986.
15. Emerson, S. D., Madison, V. S., Palermo, R. E., Waugh, D. S., Scheffler, J. E., Tsao, K. L., Kiefer, S. E., Liu, S. P. & Fry, D. C. (1995) Biochemistry 34, 6911-6918.
16. Vallee-Belisle, A., Turcotte, J. F. & Michnick, S. W. (2004) Biochemistry 43, 8447-8458.
17. Soding, J. & Lupas, A. N. (2003) Bioessays 25, 837-846.
18. Campbell-Valois, F.-X. & Michnick, S. W. (2005) Methods and Protocols in Molecular Biology, in press.
19. Pelletier, J. N., Campbell-Valois, F.-X. & Michnick, S. W. (1998) Proc. Natl. Acad. Sci. USA 95, 12141-12146.
20. Sander, C. & Schneider, R. (1991) Proteins 9, 56-68.
21. Pelletier, J. N., Arndt, K. M., Pluckthun, A. & Michnick, S. W. (1999) Nat. Biotechnol. 17, 683-690.
22. Block, C., Janknecht, R., Herrmann, C., Nassar, N. & Wittinghofer, A. (1996) Nat. Struct. Biol. 3, 244-251.
23. Fridman, M., Maruta, H., Gonez, J., Walker, F., Treutlein, H., Zeng, J. & Burgess, A. (2000) J. Biol. Chem. 275, 30363-30371.
24. Fridman, M., Walker, F., Catimel, B., Domagala, T., Nice, E. & Burgess, A. (2000) Biochemistry 39, 15603-15611.
25. Grishin, N. V. (2001) J. Struct. Biol. 134, 167-185.
26. Drake, J. W., Charlesworth, B., Charlesworth, D. & Crow, J. F. (1998) Genetics 148, 1667-1686.
27. Simons, K. T., Strauss, C. & Baker, D. (2001) J. Mol. Biol. 306, 1191-1199.
28. Waldo, G. S. (2003) Curr. Opin. Chem. Biol 7, 33-38.
29. Riddle, D. S., Santiago, J. V., Bray-Hall, S. T., Doshi, N., Grantcharova, V. P., Yi, Q. & Baker, D. (1997) Nat. Struct. Biol. 4, 805-809.
30. Lockless, S. W. & Ranganathan, R. (1999) Science 286, 295-299.
31. Liang, J. & Dill, K. A. (2001) Biophys. J. 81, 751-766.
32. Kannan, N. & Vishveshwara, S. (1999) J. Mol. Biol. 292, 441-464.
33. Lindorff-Larsen, K., Rogen, P., Paci, E., Vendruscolo, M. & Dobson, C. M. (2005) Trends Biochem. Sci. 30, 13-19.