-
1
-
-
0345167834
-
Expression of self-antigen in the thymus: A little goes a long way
-
Anderson AC, Kuchroo VK 2003 Expression of self-antigen in the thymus: a little goes a long way. J Exp Med 198:1627-1629
-
(2003)
J Exp Med
, vol.198
, pp. 1627-1629
-
-
Anderson, A.C.1
Kuchroo, V.K.2
-
2
-
-
3042698329
-
Remapping the insulin gene/IDDM2 locus in type 1 diabetes
-
Barratt BJ, Payne F, Lowe CE et al 2004 Remapping the insulin gene/IDDM2 locus in type 1 diabetes. Diabetes 53:1884-1889
-
(2004)
Diabetes
, vol.53
, pp. 1884-1889
-
-
Barratt, B.J.1
Payne, F.2
Lowe, C.E.3
-
3
-
-
3242713277
-
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
Begovich AB, Carlton VE, Honigberg LA et al 2004 A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 75:504-507
-
(2004)
Am J Hum Genet
, vol.75
, pp. 504-507
-
-
Begovich, A.B.1
Carlton, V.E.2
Honigberg, L.A.3
-
4
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini N, Musumeci L, Alonso A et al 2004 A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 36:337-338
-
(2004)
Nat Genet
, vol.36
, pp. 337-338
-
-
Bottini, N.1
Musumeci, L.2
Alonso, A.3
-
5
-
-
0037220831
-
The derivation of highly germline-competent embryonic stem cells containing NOD-derived genome
-
Brook FA, Evans EP, Lord CJ et al 2003 The derivation of highly germline-competent embryonic stem cells containing NOD-derived genome. Diabetes 52:205-208
-
(2003)
Diabetes
, vol.52
, pp. 205-208
-
-
Brook, F.A.1
Evans, E.P.2
Lord, C.J.3
-
6
-
-
0036315824
-
Insulin expression levels in the thymus modulate insulinspecific autoreactive T-cell tolerance: The mechanism by which the IDDM2 locus may predispose to diabetes
-
Chentoufi AA, Polychronakos C 2002 Insulin expression levels in the thymus modulate insulinspecific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes. Diabetes 51:1383-1390
-
(2002)
Diabetes
, vol.51
, pp. 1383-1390
-
-
Chentoufi, A.A.1
Polychronakos, C.2
-
7
-
-
0842288454
-
Proinsulin expression by Hassall's corpuscles in the mouse thymus
-
Chentoufi AA, Palumbo M, Polychronakos C 2004 Proinsulin expression by Hassall's corpuscles in the mouse thymus. Diabetes 53:354-359
-
(2004)
Diabetes
, vol.53
, pp. 354-359
-
-
Chentoufi, A.A.1
Palumbo, M.2
Polychronakos, C.3
-
8
-
-
0033521596
-
Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase
-
Cloutier JF, Veillette A 1999 Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. J Exp Med 189:111-121
-
(1999)
J Exp Med
, vol.189
, pp. 111-121
-
-
Cloutier, J.F.1
Veillette, A.2
-
9
-
-
2942724439
-
The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis
-
Greve B, Vijayakrishnan L, Kubal A et al 2004 The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis. J Immunol 173:157-163
-
(2004)
J Immunol
, vol.173
, pp. 157-163
-
-
Greve, B.1
Vijayakrishnan, L.2
Kubal, A.3
-
10
-
-
0942279640
-
PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells
-
Hasegawa K, Martin F, Huang G et al 2004 PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. Science 303:685-689
-
(2004)
Science
, vol.303
, pp. 685-689
-
-
Hasegawa, K.1
Martin, F.2
Huang, G.3
-
11
-
-
0033820560
-
NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans
-
Hill NJ, Lyons PA, Armitage N et al 2000 NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans. Diabetes 49:1744-1747
-
(2000)
Diabetes
, vol.49
, pp. 1744-1747
-
-
Hill, N.J.1
Lyons, P.A.2
Armitage, N.3
-
12
-
-
0242574700
-
Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig
-
Kremer JM, Westhovens R, Leon M et al 2003 Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. N Engl J Med 349:1907-1915
-
(2003)
N Engl J Med
, vol.349
, pp. 1907-1915
-
-
Kremer, J.M.1
Westhovens, R.2
Leon, M.3
-
13
-
-
4143105691
-
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
-
Kyogoku C, Langefeld CD, Ortmann WA et al 2004 Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 75:504-507
-
(2004)
Am J Hum Genet
, vol.75
, pp. 504-507
-
-
Kyogoku, C.1
Langefeld, C.D.2
Ortmann, W.A.3
-
14
-
-
0035968259
-
A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer
-
Lynch KW, Weiss A 2001 A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. J Biol Chem 276:24341-24347
-
(2001)
J Biol Chem
, vol.276
, pp. 24341-24347
-
-
Lynch, K.W.1
Weiss, A.2
-
15
-
-
0034075807
-
Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: Identification of a candidate segment of ancestral DNA by haplotype mapping
-
Lyons PA, Armitage N, Argentina F et al 2000a Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping. Genome Res 10:446-453
-
(2000)
Genome Res
, vol.10
, pp. 446-453
-
-
Lyons, P.A.1
Armitage, N.2
Argentina, F.3
-
16
-
-
0033711184
-
The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137
-
Lyons PA, Hancock WW, Denny P et al 2000b The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137. Immunity 13:107-115
-
(2000)
Immunity
, vol.13
, pp. 107-115
-
-
Lyons, P.A.1
Hancock, W.W.2
Denny, P.3
-
17
-
-
0035515387
-
Mapping by genetic interaction: High-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse
-
Lyons PA, Armitage N, Lord CJ et al 2001 Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse. Diabetes 50:2633-2637
-
(2001)
Diabetes
, vol.50
, pp. 2633-2637
-
-
Lyons, P.A.1
Armitage, N.2
Lord, C.J.3
-
18
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
Malek TR, Yu A, Vincek V, Scibelli P, Kong L 2002 CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 17:167-178
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
19
-
-
17344383567
-
Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice
-
Penha-Goncalves C, Moule C, Smink LJ et al 2003 Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice. Diabetes 52:1551-1556
-
(2003)
Diabetes
, vol.52
, pp. 1551-1556
-
-
Penha-Goncalves, C.1
Moule, C.2
Smink, L.J.3
-
20
-
-
7144263739
-
Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3
-
Podolin PL, Denny P, Armitage N et al 1998 Localization of two insulin-dependent diabetes (Idd) genes to the Idd10 region on mouse chromosome 3. Mamm Genome 9:283-286
-
(1998)
Mamm Genome
, vol.9
, pp. 283-286
-
-
Podolin, P.L.1
Denny, P.2
Armitage, N.3
-
21
-
-
0142259712
-
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
-
Rudd CE, Schneider H 2003 Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat Rev Immunol 3:544-556
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 544-556
-
-
Rudd, C.E.1
Schneider, H.2
-
22
-
-
7044253358
-
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
-
Smyth DJ, Cooper JD, Collins JE et al 2004 Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes 53:3020-3023
-
(2004)
Diabetes
, vol.53
, pp. 3020-3023
-
-
Smyth, D.J.1
Cooper, J.D.2
Collins, J.E.3
-
23
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JM, Esposito L et al 2003 Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423:506-511
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
-
24
-
-
20244373351
-
Localization of a type 1 diabetes locus in the IL2RA/CD25 region using tag single nucleotide polymorphisms
-
in press
-
Vella A, Cooper JD, Lowe CE et al 2005 Localization of a type 1 diabetes locus in the IL2RA/CD25 region using tag single nucleotide polymorphisms. Am J Hum Genet, in press
-
(2005)
Am J Hum Genet
-
-
Vella, A.1
Cooper, J.D.2
Lowe, C.E.3
-
25
-
-
2442496304
-
An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells
-
Vijayakrishnan L, Slavik JM, Illes Z et al 2004 An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells. Immunity 20:563-575
-
(2004)
Immunity
, vol.20
, pp. 563-575
-
-
Vijayakrishnan, L.1
Slavik, J.M.2
Illes, Z.3
-
26
-
-
0037028155
-
The mosaic structure of variation in the laboratory mouse genome
-
Wade CM, Kulbokas EJ, 3rd, Kirby AW et al 2002 The mosaic structure of variation in the laboratory mouse genome. Nature 420:574-578
-
(2002)
Nature
, vol.420
, pp. 574-578
-
-
Wade, C.M.1
Kulbokas 3rd, E.J.2
Kirby, A.W.3
-
27
-
-
0027948090
-
Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes
-
Wicker LS, Todd JA, Prins JB et al 1994 Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes. J Exp Med 180:1705-1713
-
(1994)
J Exp Med
, vol.180
, pp. 1705-1713
-
-
Wicker, L.S.1
Todd, J.A.2
Prins, J.B.3
-
28
-
-
0028922437
-
Genetic control of autoimmune diabetes in the NOD mouse
-
Wicker LS, Todd JA, Peterson LB 1995 Genetic control of autoimmune diabetes in the NOD mouse. Annu Rev Immunol 13:179-200
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 179-200
-
-
Wicker, L.S.1
Todd, J.A.2
Peterson, L.B.3
-
29
-
-
2942739158
-
Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse
-
Wicker LS, Chamberlain G, Hunter K et al 2004 Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse. J Immunol 173:164-173
-
(2004)
J Immunol
, vol.173
, pp. 164-173
-
-
Wicker, L.S.1
Chamberlain, G.2
Hunter, K.3
-
30
-
-
0037452982
-
Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse
-
Wiltshire T, Pletcher MT, Batalov S et al 2003 Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc Natl Acad Sci USA 100:3380-3385
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3380-3385
-
-
Wiltshire, T.1
Pletcher, M.T.2
Batalov, S.3
-
31
-
-
3042840998
-
Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice
-
Yalcin B, Fullerton J, Miller S et al 2004 Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. Proc Natl Acad Sci USA 101:9734-9739
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9734-9739
-
-
Yalcin, B.1
Fullerton, J.2
Miller, S.3
-
32
-
-
0036699521
-
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus
-
Yokoi N, Komeda K, Wang HY et al 2002 Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet 31:391-394
-
(2002)
Nat Genet
, vol.31
, pp. 391-394
-
-
Yokoi, N.1
Komeda, K.2
Wang, H.Y.3
|