-
1
-
-
2942536597
-
New concepts in breast cancer therapy
-
Snyder RD. New concepts in breast cancer therapy. Intern Med J 2004;34:266-9.
-
(2004)
Intern Med J
, vol.34
, pp. 266-269
-
-
Snyder, R.D.1
-
2
-
-
4043101164
-
Advances in diagnosis and therapy of breast cancer between the 20th and the 21st centuries
-
Losacco T, Ventrella N, Casale F, Logrieco S, Santacroce L. Advances in diagnosis and therapy of breast cancer between the 20th and the 21st centuries. Clin Ther 2004;155:33-40.
-
(2004)
Clin Ther
, vol.155
, pp. 33-40
-
-
Losacco, T.1
Ventrella, N.2
Casale, F.3
Logrieco, S.4
Santacroce, L.5
-
3
-
-
1642349616
-
Genomic medicine. Gene expression tests foretell breast cancer's future
-
Garber K. Genomic medicine. Gene expression tests foretell breast cancer's future. Science 2004;303:1754-5.
-
(2004)
Science
, vol.303
, pp. 1754-1755
-
-
Garber, K.1
-
5
-
-
0028984843
-
Bcl-xL and Bcl-2 repress a common pathway of cell death
-
Chao DT, Linette GP, Boise LH, White LS, Thompson CB, Korsmeyer SJ. Bcl-xL and Bcl-2 repress a common pathway of cell death. J Exp Med 1995;182:821-8.
-
(1995)
J Exp Med
, vol.182
, pp. 821-828
-
-
Chao, D.T.1
Linette, G.P.2
Boise, L.H.3
White, L.S.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
6
-
-
0028979439
-
Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis
-
Dole MG, Jasty R, Cooper MJ, Thompson CB, Nunez G, Castle VP. Bcl-xL is expressed in neuroblastoma cells and modulates chemotherapy-induced apoptosis. Cancer Res 1995;55:2576-82.
-
(1995)
Cancer Res
, vol.55
, pp. 2576-2582
-
-
Dole, M.G.1
Jasty, R.2
Cooper, M.J.3
Thompson, C.B.4
Nunez, G.5
Castle, V.P.6
-
7
-
-
0030615086
-
Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL-60 cells
-
Ibrado AM, Liu L, Bhalla K. Bcl-xL overexpression inhibits progression of molecular events leading to paclitaxel-induced apoptosis of human acute myeloid leukemia HL-60 cells. Cancer Res 1997;57:1109-15.
-
(1997)
Cancer Res
, vol.57
, pp. 1109-1115
-
-
Ibrado, A.M.1
Liu, L.2
Bhalla, K.3
-
8
-
-
0242317385
-
Small RNA: Can RNA interference be exploited for therapy?
-
Wall NR, Shi Y. Small RNA: can RNA interference be exploited for therapy? Lancet 2003;362:1401-3.
-
(2003)
Lancet
, vol.362
, pp. 1401-1403
-
-
Wall, N.R.1
Shi, Y.2
-
9
-
-
1642282641
-
Silencing expression of the clusterin/apolipoprotein i gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress
-
Trougakos IP, So A, Jansen B, et al. Silencing expression of the clusterin/apolipoprotein i gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress. Cancer Res 2004;64:1834-42.
-
(2004)
Cancer Res
, vol.64
, pp. 1834-1842
-
-
Trougakos, I.P.1
So, A.2
Jansen, B.3
-
10
-
-
8544229212
-
A novel human phosphatidylethanolamine-binding protein resists TNFα-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization
-
Wang X, Li N, Liu B, et al. A novel human phosphatidylethanolamine- binding protein resists TNFα-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization. J Biol Chem 2004;279:45855-64.
-
(2004)
J Biol Chem
, vol.279
, pp. 45855-45864
-
-
Wang, X.1
Li, N.2
Liu, B.3
-
11
-
-
4444243683
-
A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death
-
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death. Science 2004;305:1471-4.
-
(2004)
Science
, vol.305
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
12
-
-
0642283970
-
Regulation of proliferation, survival and apoptosis by members of the TNF superfamily
-
Gaur U, Aggarwal BB. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol 2003;66:1403-8.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1403-1408
-
-
Gaur, U.1
Aggarwal, B.B.2
-
14
-
-
0027298576
-
Induction of cellular p53 activity by DNA-damaging agents and growth arrest
-
Zhan Q, Carrier F, Fornace AJ. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 1993;13:4242-50.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4242-4250
-
-
Zhan, Q.1
Carrier, F.2
Fornace, A.J.3
-
15
-
-
1842687879
-
Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin
-
Yannada T, Hiraoka Y, Ikehata M, et al. Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin. Proc Natl Acad Sci USA 2004;101:4770-5.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4770-4775
-
-
Yannada, T.1
Hiraoka, Y.2
Ikehata, M.3
-
16
-
-
0037039381
-
Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent
-
Chang BD, Swift ME, Shen M, Fang J, Broude EV, Roninson IB. Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent. Proc Natl Acad Sci U S A 2002;99:389-94.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 389-394
-
-
Chang, B.D.1
Swift, M.E.2
Shen, M.3
Fang, J.4
Broude, E.V.5
Roninson, I.B.6
-
17
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995;80:293-9.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
18
-
-
0028292480
-
Identification of a p53-dependent negative response element in the bcl-2 gene
-
Miyashita T, Harigai M, Hanada M, Reed JC. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 1994;54:3131-5.
-
(1994)
Cancer Res
, vol.54
, pp. 3131-3135
-
-
Miyashita, T.1
Harigai, M.2
Hanada, M.3
Reed, J.C.4
-
19
-
-
0034617077
-
ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UVradiation
-
She QB, Chen N, Dong Z. ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UVradiation. J Biol Chem 2000;275:20444-9.
-
(2000)
J Biol Chem
, vol.275
, pp. 20444-20449
-
-
She, Q.B.1
Chen, N.2
Dong, Z.3
-
21
-
-
0035863395
-
Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites
-
Idres N, Benoit G, Flexor MA, Lanotte M, Chabot GG. Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites. Cancer Res 2001;61:700-5.
-
(2001)
Cancer Res
, vol.61
, pp. 700-705
-
-
Idres, N.1
Benoit, G.2
Flexor, M.A.3
Lanotte, M.4
Chabot, G.G.5
-
22
-
-
0031149132
-
Exposure of phosphatidylethanolamine on the surface of apoptotic cells
-
Emoto K, Toyama SN, Karasuyama H, Inoue K, Umeda M. Exposure of phosphatidylethanolamine on the surface of apoptotic cells. Exp Cell Res 1997;232:430-4.
-
(1997)
Exp Cell Res
, vol.232
, pp. 430-434
-
-
Emoto, K.1
Toyama, S.N.2
Karasuyama, H.3
Inoue, K.4
Umeda, M.5
-
23
-
-
0034931503
-
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
-
Han Z, Boyle DL, Chang L, et al. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 2001;108:73-81.
-
(2001)
J Clin Invest
, vol.108
, pp. 73-81
-
-
Han, Z.1
Boyle, D.L.2
Chang, L.3
-
24
-
-
0033563101
-
Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
-
Baud V, Liu ZG, Bennett B, Suzuki N, Xia Y, Karin M. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev 1999;13:1297-308.
-
(1999)
Genes Dev
, vol.13
, pp. 1297-1308
-
-
Baud, V.1
Liu, Z.G.2
Bennett, B.3
Suzuki, N.4
Xia, Y.5
Karin, M.6
-
25
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z, Xiong J, Takeuchi M, Kurama T, Goeddel DV. TRAF6 is a signal transducer for interleukin-1. Nature 1996;383:443-6.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
26
-
-
2342461756
-
To die or not to die: How does p53 decide?
-
Slee EA, O'Connor DJ, Lu X. To die or not to die: how does p53 decide? Oncogene 2004;23:2809-18.
-
(2004)
Oncogene
, vol.23
, pp. 2809-2818
-
-
Slee, E.A.1
O'Connor, D.J.2
Lu, X.3
-
27
-
-
0032169459
-
JNK targets p53 ubiquitination and degradation in nonstressed cells
-
Fuchs SY, Adler V, Buschmann T. JNK targets p53 ubiquitination and degradation in nonstressed cells. Genes Dev 1998;12:2658-63.
-
(1998)
Genes Dev
, vol.12
, pp. 2658-2663
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
-
28
-
-
0034680896
-
Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin
-
Persons DL, Yazlovitskaya EM, Pelling JC. Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin. J Biol Chem 2000;275:35778-85.
-
(2000)
J Biol Chem
, vol.275
, pp. 35778-35785
-
-
Persons, D.L.1
Yazlovitskaya, E.M.2
Pelling, J.C.3
-
29
-
-
0037066686
-
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
-
Tang D, Wu D, Hirao A, et al. ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J Biol Chem 2002;277:12710-7.
-
(2002)
J Biol Chem
, vol.277
, pp. 12710-12717
-
-
Tang, D.1
Wu, D.2
Hirao, A.3
-
31
-
-
2442639165
-
Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death
-
Yeh PY, Chuang SE, Yeh KH, Song YC, Chang LL, Cheng AL. Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death. Oncogene 2004;23:3580-8.
-
(2004)
Oncogene
, vol.23
, pp. 3580-3588
-
-
Yeh, P.Y.1
Chuang, S.E.2
Yeh, K.H.3
Song, Y.C.4
Chang, L.L.5
Cheng, A.L.6
-
32
-
-
0028966941
-
p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1
-
Milne DM, Campbell LE, Campbell DG, Meek DW. p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1. J Biol Chem 1995;270:5511-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 5511-5518
-
-
Milne, D.M.1
Campbell, L.E.2
Campbell, D.G.3
Meek, D.W.4
-
33
-
-
0030835430
-
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1
-
Woods D, Parry D, Cherwinski H, Bosch E, Lees E, McMahon M. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1. Mol Cell Biol 1997;17:5598-611.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5598-5611
-
-
Woods, D.1
Parry, D.2
Cherwinski, H.3
Bosch, E.4
Lees, E.5
McMahon, M.6
-
34
-
-
0030871667
-
High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1
-
Sewing A, Wiseman B, Lloyd AC, Land H. High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1. Mol Cell Biol 1997;17:5588-97.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5588-5597
-
-
Sewing, A.1
Wiseman, B.2
Lloyd, A.C.3
Land, H.4
-
36
-
-
0032955729
-
Adenovirus-mediated TNFα gene transfer induces significant tumor regression in mice
-
Wright P, Braun R, Babiuk L, et al. Adenovirus-mediated TNFα gene transfer induces significant tumor regression in mice. Cancer Biother Radiopharm 1999;14:49-57.
-
(1999)
Cancer Biother Radiopharm
, vol.14
, pp. 49-57
-
-
Wright, P.1
Braun, R.2
Babiuk, L.3
-
37
-
-
0033847207
-
Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature
-
Stoelcker B, Ruhland B, Hehlgans T, Bluethmann H, Luther T, Mannel DN. Tumor necrosis factor induces tumor necrosis via tumor necrosis factor receptor type 1-expressing endothelial cells of the tumor vasculature. Am J Pathol 2000;156:1171-6.
-
(2000)
Am J Pathol
, vol.156
, pp. 1171-1176
-
-
Stoelcker, B.1
Ruhland, B.2
Hehlgans, T.3
Bluethmann, H.4
Luther, T.5
Mannel, D.N.6
-
38
-
-
0037421484
-
NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia
-
Dajee M, Lazarov M, Zhang JY, et al. NF-κB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature 2003;421:639-43.
-
(2003)
Nature
, vol.421
, pp. 639-643
-
-
Dajee, M.1
Lazarov, M.2
Zhang, J.Y.3
-
39
-
-
0037651115
-
PPAR-γ receptor ligands: Novel therapy for pituitary adenomas
-
Heaney AP, Fernando M, Melmed S. PPAR-γ receptor ligands: novel therapy for pituitary adenomas. J Clin Invest 2003;111:1381-8.
-
(2003)
J Clin Invest
, vol.111
, pp. 1381-1388
-
-
Heaney, A.P.1
Fernando, M.2
Melmed, S.3
-
40
-
-
0038751860
-
p53 downstream targets and chemosensitivity
-
Sax JK, El-Deiry WS. p53 downstream targets and chemosensitivity. Cell Death Differ 2003;10:413-7.
-
(2003)
Cell Death Differ
, vol.10
, pp. 413-417
-
-
Sax, J.K.1
El-Deiry, W.S.2
-
41
-
-
0034656243
-
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
-
Zhao R, Gish K, Murphy M, et al. Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev 2000;14:981-93.
-
(2000)
Genes Dev
, vol.14
, pp. 981-993
-
-
Zhao, R.1
Gish, K.2
Murphy, M.3
-
42
-
-
0035953394
-
DNA microarrays identification of primary and secondary target genes regulated by p53
-
Kannan K, Amariglio N, Rechavi G, et al. DNA microarrays identification of primary and secondary target genes regulated by p53. Oncogene 2001;20:2225-34.
-
(2001)
Oncogene
, vol.20
, pp. 2225-2234
-
-
Kannan, K.1
Amariglio, N.2
Rechavi, G.3
-
43
-
-
0034745050
-
2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress
-
2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress. Mol Cell Biol 2001;21:2743-54.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 2743-2754
-
-
Bushmann, T.1
Potapova, O.2
Ivanov, V.N.3
|