Inhibition of the RhoA/Rho kinase system attenuates catecholamine biosynthesis in PC 12 rat pheochromocytoma cells

Biochimica et Biophysica Acta - General Subjects

Volumn 1726, Issue 1, 2005, Pages 28-33

  Fukuda, Toshiyuki ^a   Takekoshi, Kazuhiro ^a   Nanmoku, Toru ^a   Ishii, Kiyoaki ^a   Isobe, Kazumasa ^a   Kawakami, Yasushi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

C3 toxin; PC12 cell; RhoA Rho kinase system; Tyrosine hydroxylase (TH); Y27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CATECHOLAMINE; NICOTINE; PROTEIN INHIBITOR; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RHO KINASE; RHO KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE; TOXIN; TYROSINE 3 MONOOXYGENASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTICHOLINERGIC EFFECT; ARTICLE; CATECHOLAMINE RELEASE; CATECHOLAMINE SYNTHESIS; CHROMAFFIN CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INHIBITION KINETICS; MOLECULAR DYNAMICS; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT;

AMIDES; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BOTULINUM TOXINS; CATECHOLAMINES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA PRIMERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE TRANSFERASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NICOTINE; PC12 CELLS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RATS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 27144504449     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2005.08.008     Document Type: Article

References (31)

1. L. Van Aelst, and C. D'Souza-Schorey Rho GTPases and signaling networks Genes Dev. 11 1997 2295 2322
2. A. Hall Rho GTPases and the actin cytoskeleton Science 279 1998 509 514
3. K. Kaibuchi, S. Kuroda, and M. Amano Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells Annu. Rev. Biochem. 68 1999 459 486
4. U. Laufs, and J.K. Liao Targeting Rho in cardiovascular disease Circ. Res. 87 2000 526 528
5. J.C. Norman, L.S. Price, A.J. Ridley, and A. Koffer The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways Mol. Cell. Biol. 7 1996 1429 1442
6. T. Matsui, M. Amano, T. Yamamoto, K. Chihara, M. Nakafuku, M. Ito, T. Nakano, K. Okawa, A. Iwamatsu, and K. Kaibuchi Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho EMBO J. 15 1996 2208 2216
7. H. Katoh, J. Aoki, Y. Yamaguchi, Y. Kitano, A. Ichikawa, and M. Negishi Constitutively active Galpha12, Galpha13, and Galphaq induce Rho-dependent neurite retraction through different signaling pathways J. Biol. Chem. 273 1998 28700 28707
8. Y. Yamaguchi, H. Katoh, H. Yasui, J. Aoki, K. Nakamura, and M. Negishi Galpha(12) and galpha(13) inhibit Ca(2+)-dependent exocytosis through Rho/Rho-associated kinase-dependent pathway J. Neurochem. 75 2000 708 717
9. C. Frantz, T. Coppola, and R. Regazzi Involvement of Rho GTPases and their effectors in the secretory process of PC12 cells Exp. Cell Res. 273 2002 119 126
10. S. Gasman, S. Chasserot-Golaz, M.R. Popoff, D. Aunis, and M.F. Bader Involvement of Rho GTPases in calcium-regulated exocytosis from adrenal chromaffin cells J. Cell Sci. 112 1999 4763 4771
11. S. Gasman, S. Chasserot-Golaz, M.F. Bader, and N. Vitale Regulation of exocytosis in adrenal chromaffin cells: focus on ARF and Rho GTPases Cell Signal 15 2003 893 899
12. J.W. Haycock Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40 J. Biol. Chem. 265 1990 11682 11691
13. J.W. Haycock, and A.R. Wakade Activation and multiple-site phosphorylation of tyrosine hydroxylase in perfused rat adrenal glands J. Neurochem. 58 1992 57 64
14. R.E. Zigmond, M.A. Schwarzschild, and A.R. Rittenhouse Acute regulation of tyrosine hydroxylase by nerve activity and by neurotransmitters via phosphorylation Annu. Rev. Neurosci. 12 1989 415 461
15. J.W. Haycock Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40 J. Biol. Chem. 265 1990 11682 11691
16. L.R. Bevilaque, M.E. Graham, P.R. Dunkley, E.I. von Nagy-Felsobuki, and P.W. Dickson Phosphorylation of Ser(19) alters the conformation of tyrosine hydroxylase to increase the rate of phosphorylation of Ser(40) J. Biol. Chem. 276 2001 40411 40416
17. D.G. Campbell, D.G. Hardie, and P.R. Vulliet Identification of four phosphorylation sites in the N-terminal region of tyrosine hydroxylase J. Biol. Chem. 261 1986 10489 10492
18. O. Hwang, M.L. Kim, and J.D. Lee Differential induction of gene expression of catecholamine biosynthetic enzymes and preferential increase in norepinephrine by forskolin Biochem. Pharmacol. 48 1994 1927 1934
19. B. Le Bourdelles, S. Boularand, C. Boni, P. Horellou, S. Dumas, B. Grima, and J. Mallet Analysis of the 5′ region of the human tyrosine hydroxylase gene: combinatorial patterns of exon splicing generate multiple regulated tyrosine hydroxylase isoforms J. Neurochem. 50 1988 988 991
20. F. Cambi, B. Fung, and D. Chikaraishi 5′ flanking DNA sequences direct cell-specific expression of rat tyrosine hydroxylase J. Neurochem. 53 1989 1656 1659
21. K. Takekoshi, K. Ishii, Y. Kawakami, K. Isobe, and T. Nakai kappa-opioid inhibits catecholamine biosynthesis in PC12 rat pheochromocytoma cell FEBS Lett. 477 2000 273 277
22. X.D. Ren, W.B. Kiosses, and M.A. Schwartz Regulation of the small GTP-binding protein Rho listtext1. by cell adhesion and the cytoskeleton EMBO J. 18 1999 578 585
23. T. Kumai, M. Tanaka, T. Tateishi, M. Watanabe, H. Nakura, M. Asoh, and S. Kobayashi Effects of anti-androgen treatment on the catecholamine synthetic pathway in the adrenal medulla of spontaneously hypertensive rats Naunyn-Schmiedeberg's Arch. Pharmacol. 357 1998 620 624
24. Y. Kitaoka, T. Kumai, K. Isenoumi, Y. Kitaoka, M. Motoki, S. Kobayashi, and S. Ueno Neuroprotective effect of nitric oxide against NMDA-induced neurotoxicity in the rat retina is associated with tyrosine hydroxylase expression Brain Res. 977 2003 46 54
25. L.i. Quanwen, C.S. Ho, V. Marinescu, H. Bhatti, G.M. Bokoch, S.A. Ernst, W.R. Holz, and E.L. Stuenkel Facilitation of Ca(2+)-dependent exocytosis by Rac1-GTPase in bovine chromaffin cells J. Physiol. 550 2003 431 445
26. L. Bobrovskaya, P.R. Dunkley, and P.W. Dickson Phosphorylation of Ser19 increases both Ser40 phosphorylation and enzyme activity of tyrosine hydroxylase in intact cells J. Neurochem. 90 2004 857 864
27. T. Ishizaki, M. Uehata, I. Tamechika, J. Keel, K. Nonomura, M. Maekawa, and S. Narumiya Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases Mol. Pharmacol. 57 2000 976 983
28. M. Uehata, T. Ishizaki, H. Satoh, T. Ono, T. Kawahara, T. Morishita, H. Tamakawa, K. Yamagami, and J. Inui Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension Nature 389 1997 990 994
29. T.J. Batchelor, J.R. Sadaba, A. Ishola, P. Pacaud, C.M. Munsch, and D.J. Beech Rho-kinase inhibitors prevent agonist-induced vasospasm in human internal mammary artery Br. J. Pharmacol. 132 2001 302 308
30. M. Tsutsui, N. Yanagihara, E. Miyamoto, A. Kuroiwa, and F. Izumi Correlation of activation of Ca2+/calmodulin-dependent protein kinase II with catecholamine secretion and tyrosine hydroxylase activation in cultured bovine adrenal medullary cells Mol. Pharmacol. 46 1994 1041 1047
31. Y. Kureishi, S. Kobayashi, M. Amano, K. Kimura, H. Kanaide, T. Nakano, K. Kaibuchi, and M. Ito Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation J. Biol. Chem. 272 1997 12257 12260