메뉴 건너뛰기




Volumn 7, Issue 9, 1996, Pages 1429-1442

The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYTOCHALASIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATASE; PHALLOIDIN; RHO FACTOR;

EID: 0029809141     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.9.1429     Document Type: Article
Times cited : (113)

References (47)
  • 1
    • 0026795613 scopus 로고
    • Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: P67-phox, p47-phox, p21-rac1, and cytochrome b245
    • Abo, A., Boyhan, A., West, I., Thrasher, A., and Segal, A. (1992). Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21-rac1, and cytochrome b245. J. Biol. Chem. 267, 16767-16770.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16767-16770
    • Abo, A.1    Boyhan, A.2    West, I.3    Thrasher, A.4    Segal, A.5
  • 2
    • 0024584734 scopus 로고
    • The Rho gene product expressed in E. coli is a substrate for botulinum ADP-ribosyltransferase C3
    • Aktories, K., Braun, S., Rosener, S., Just, I., and Hall, A. (1989). The Rho gene product expressed in E. coli is a substrate for botulinum ADP-ribosyltransferase C3. Biochem. Biophys. Res. Commun. 158, 209-213.
    • (1989) Biochem. Biophys. Res. Commun. , vol.158 , pp. 209-213
    • Aktories, K.1    Braun, S.2    Rosener, S.3    Just, I.4    Hall, A.5
  • 3
    • 0025075352 scopus 로고
    • Exocytosis in mast cells by basic secretagogues: Evidence for direct activation of GTP-binding proteins
    • Aridor, M., Traub, L.M., and Sagi-Eisenberg, R. (1990). Exocytosis in mast cells by basic secretagogues: evidence for direct activation of GTP-binding proteins. J. Cell Biol. 111, 909-917.
    • (1990) J. Cell Biol. , vol.111 , pp. 909-917
    • Aridor, M.1    Traub, L.M.2    Sagi-Eisenberg, R.3
  • 4
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • Boguski, M.S., and McCormick, F. (1993). Proteins regulating Ras and its relatives. Nature 366, 643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 5
    • 0028937025 scopus 로고
    • Secretion from permeabilised mast cells is enhanced by addition of gelsolin: Contrasting effects of endogenous gelsolin
    • Borovikov, Y.S., Norman, J.C., Price, L.S., Weeds, A., and Koffer, A. (1995). Secretion from permeabilised mast cells is enhanced by addition of gelsolin: contrasting effects of endogenous gelsolin. J. Cell Sci. 108, 657-666.
    • (1995) J. Cell Sci. , vol.108 , pp. 657-666
    • Borovikov, Y.S.1    Norman, J.C.2    Price, L.S.3    Weeds, A.4    Koffer, A.5
  • 6
    • 0027372389 scopus 로고
    • Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein
    • Bowman, E.P., Uhlinger, D.J., and Lambeth, J.D. (1993). Neutrophil phospholipase D is activated by a membrane-associated Rho family small molecular weight GTP-binding protein. J. Biol. Chem. 268, 21509-21512.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21509-21512
    • Bowman, E.P.1    Uhlinger, D.J.2    Lambeth, J.D.3
  • 7
    • 0023321856 scopus 로고
    • Reorganisation of peripheral actin filaments as a prelude to exocytosis
    • Burgoyne, R.D., and Cheek, T.R. (1985). Reorganisation of peripheral actin filaments as a prelude to exocytosis. Biosci. Rep. 7, 281-288.
    • (1985) Biosci. Rep. , vol.7 , pp. 281-288
    • Burgoyne, R.D.1    Cheek, T.R.2
  • 8
    • 0028036684 scopus 로고
    • The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells
    • Chong, L.D., Traynor Kaplan, A., Bokoch, G.M., and Schwartz, M.A. (1994). The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 79, 507-513.
    • (1994) Cell , vol.79 , pp. 507-513
    • Chong, L.D.1    Traynor Kaplan, A.2    Bokoch, G.M.3    Schwartz, M.A.4
  • 9
    • 0023575327 scopus 로고
    • Two G-proteins act in series to control stimulus-secretion coupling in mast cells: Use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis
    • Cockcroft, S., Howell, T.W., and Gomperts, B.D. (1987). Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis. J. Cell Biol. 105, 2745-2750.
    • (1987) J. Cell Biol. , vol.105 , pp. 2745-2750
    • Cockcroft, S.1    Howell, T.W.2    Gomperts, B.D.3
  • 10
    • 0023427610 scopus 로고
    • Effects of cytochalasin and phalloidin on actin
    • Cooper, J.A. (1987). Effects of cytochalasin and phalloidin on actin. J. Cell Biol. 105, 1473-1478.
    • (1987) J. Cell Biol. , vol.105 , pp. 1473-1478
    • Cooper, J.A.1
  • 12
    • 0027459033 scopus 로고
    • A role for synaptotagmin (p65) in regulated exocytosis
    • Elferink, L.A., Peterson, M.R., and Scheller, R.H. (1993). A role for synaptotagmin (p65) in regulated exocytosis. Cell 72, 153-159.
    • (1993) Cell , vol.72 , pp. 153-159
    • Elferink, L.A.1    Peterson, M.R.2    Scheller, R.H.3
  • 14
    • 0027052132 scopus 로고
    • Ras-related GTPases and the cytoskeleton
    • Hall, A. (1992). Ras-related GTPases and the cytoskeleton. Mol. Biol. Cell 3, 475-479.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 475-479
    • Hall, A.1
  • 15
    • 0029117595 scopus 로고
    • Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilised human platelets
    • Hartwig, J.H., Bokoch, G.M., Carpenter, C.L., Janmey, P.A., Taylor, L.A., Toker, A., and Stossel, T.P. (1995). Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilised human platelets. Cell 82, 643-653.
    • (1995) Cell , vol.82 , pp. 643-653
    • Hartwig, J.H.1    Bokoch, G.M.2    Carpenter, C.L.3    Janmey, P.A.4    Taylor, L.A.5    Toker, A.6    Stossel, T.P.7
  • 17
    • 0023374395 scopus 로고
    • 2+ and guanine nucleotides in exocytotic secretion from permeabilised mast cells
    • 2+ and guanine nucleotides in exocytotic secretion from permeabilised mast cells. J. Cell Biol. 105, 191-197.
    • (1987) J. Cell Biol. , vol.105 , pp. 191-197
    • Howell, T.W.1    Cockcroft, S.2    Gomperts, B.D.3
  • 18
    • 0028282547 scopus 로고
    • Cellular tensegrity: Exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis
    • Ingber, D.E., et al. (1994). Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. Int. Rev. Cytol. 150, 173-224.
    • (1994) Int. Rev. Cytol. , vol.150 , pp. 173-224
    • Ingber, D.E.1
  • 19
    • 0027403049 scopus 로고
    • Calcium-induced secretion from permeabilised rat mast cells: Requirements for guanine nucleotides
    • Koffer, A. (1993). Calcium-induced secretion from permeabilised rat mast cells: requirements for guanine nucleotides. Biochim. Biophys. Acta 1176, 236-244.
    • (1993) Biochim. Biophys. Acta , vol.1176 , pp. 236-244
    • Koffer, A.1
  • 20
    • 0025103774 scopus 로고
    • Changes in the state of actin during the exocytotic reaction of permeabilised rat mast cells
    • Koffer, A., Tatham, P.E.R., and Gomperts, B.D. (1990). Changes in the state of actin during the exocytotic reaction of permeabilised rat mast cells. J. Cell Biol. 111, 919-927.
    • (1990) J. Cell Biol. , vol.111 , pp. 919-927
    • Koffer, A.1    Tatham, P.E.R.2    Gomperts, B.D.3
  • 21
  • 22
    • 0023854786 scopus 로고
    • Evidence that the phosphatidylinositol cycle is linked to cell motility
    • Lassing, I., and Lindberg, U. (1988). Evidence that the phosphatidylinositol cycle is linked to cell motility. Exp. Cell Res. 174, 1-15.
    • (1988) Exp. Cell Res. , vol.174 , pp. 1-15
    • Lassing, I.1    Lindberg, U.2
  • 23
    • 0027538024 scopus 로고
    • The membrane fusion events in degranulating guinea pig eosinophils
    • Lindau, M., Nüsse, O., Bennett, J.P., and Cromwell, O. (1993). The membrane fusion events in degranulating guinea pig eosinophils. J. Cell Sci. 104, 203-209.
    • (1993) J. Cell Sci. , vol.104 , pp. 203-209
    • Lindau, M.1    Nüsse, O.2    Bennett, J.P.3    Cromwell, O.4
  • 24
    • 0007114441 scopus 로고
    • Overcoming barriers to exocytosis
    • Linstedt, A.D., and Kelly, R.B. (1987). Overcoming barriers to exocytosis. Trends Neurosci. 10, 446-448.
    • (1987) Trends Neurosci. , vol.10 , pp. 446-448
    • Linstedt, A.D.1    Kelly, R.B.2
  • 25
    • 0027999909 scopus 로고
    • Activation of rat liver phospholipase D by the small GTP-binding protein RhoA
    • Malcolm, C.K., Ross, A.H., Qiu, R.G., Symons, M., and Exton, J.H. (1994). Activation of rat liver phospholipase D by the small GTP-binding protein RhoA. J. Biol. Chem. 269, 25951-25954.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25951-25954
    • Malcolm, C.K.1    Ross, A.H.2    Qiu, R.G.3    Symons, M.4    Exton, J.H.5
  • 26
    • 0028078824 scopus 로고
    • A brain serine/threonine protein kinase activated by cdc42 and Rac1
    • Manser, E., Leung, T., Salihuddin, H., Zhao, Z., and Lim, L. (1994). A brain serine/threonine protein kinase activated by cdc42 and Rac1. Nature 367, 40-46.
    • (1994) Nature , vol.367 , pp. 40-46
    • Manser, E.1    Leung, T.2    Salihuddin, H.3    Zhao, Z.4    Lim, L.5
  • 28
    • 0026700090 scopus 로고
    • A Rho gene product in human blood platelets. II. Effects of the ADP-ribosylation by botulinum C3 ADP-ribosyltransferase on platelet aggregation
    • Morii, N., Teru-uchi, T., Tominaga, T., Kumagai, N., Kozaki, S., Ushikubi, F., and Narumiya, S. (1992). A Rho gene product in human blood platelets. II. Effects of the ADP-ribosylation by botulinum C3 ADP-ribosyltransferase on platelet aggregation. J. Biol. Chem. 267, 20921-20926.
    • (1992) J. Biol. Chem. , vol.267 , pp. 20921-20926
    • Morii, N.1    Teru-uchi, T.2    Tominaga, T.3    Kumagai, N.4    Kozaki, S.5    Ushikubi, F.6    Narumiya, S.7
  • 29
    • 0028889137 scopus 로고
    • Actin disassembly is a sufficient final trigger for exocytosis in nonexcitable cells
    • Muallem, S., Kwiatkowska, K., Xu, X., and Yin, H.L. (1995). Actin disassembly is a sufficient final trigger for exocytosis in nonexcitable cells. J. Cell Biol. 128, 589-598.
    • (1995) J. Cell Biol. , vol.128 , pp. 589-598
    • Muallem, S.1    Kwiatkowska, K.2    Xu, X.3    Yin, H.L.4
  • 30
    • 0028961293 scopus 로고
    • Rho, Rac, and Cdc42 regulate the assembly of multi-molecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes, C.D., and Hall, A. (1995). Rho, Rac, and Cdc42 regulate the assembly of multi-molecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 31
    • 0028070036 scopus 로고
    • Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins
    • Norman, J.C., Price, L.S., Ridley, A.J., Hall, A., and Koffer, A. (1994). Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins. J. Cell Biol. 126, 1005-1015.
    • (1994) J. Cell Biol. , vol.126 , pp. 1005-1015
    • Norman, J.C.1    Price, L.S.2    Ridley, A.J.3    Hall, A.4    Koffer, A.5
  • 32
  • 34
    • 0021847682 scopus 로고
    • Reorganization of a-fodrin by stimulation in secretory cells
    • Perrin, D., and Aunis, D. (1985). Reorganization of a-fodrin by stimulation in secretory cells. Nature 315, 589-592.
    • (1985) Nature , vol.315 , pp. 589-592
    • Perrin, D.1    Aunis, D.2
  • 35
    • 0026515691 scopus 로고
    • 2+-mediated secretion in parotid acinar cells is associated with reversible changes in the organization of the cytoskeleton
    • 2+-mediated secretion in parotid acinar cells is associated with reversible changes in the organization of the cytoskeleton. J. Cell Biol. 116, 127-134.
    • (1992) J. Cell Biol. , vol.116 , pp. 127-134
    • Perrin, D.1    Möller, K.2    Hanke, K.3    Söling, H.4
  • 36
    • 0029139385 scopus 로고
    • Small GTPases, Rac and Rho, as regulators of secretion in mast cells
    • Price, L.S., Norman, J.C., Ridley, A.J., and Koffer, A. (1995). Small GTPases, Rac and Rho, as regulators of secretion in mast cells. Curr. Biol. 5, 68-73.
    • (1995) Curr. Biol. , vol.5 , pp. 68-73
    • Price, L.S.1    Norman, J.C.2    Ridley, A.J.3    Koffer, A.4
  • 37
    • 0026778133 scopus 로고
    • The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley, A.J., and Hall, A. (1992). The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 38
    • 0028321785 scopus 로고
    • Signal transduction pathways regulating Rho-mediated stress fiber formation: Requirement for a tyrosine kinase
    • Ridley, A.J., and Hall, A. (1994). Signal transduction pathways regulating Rho-mediated stress fiber formation: requirement for a tyrosine kinase. EMBO J. 13, 2600-2610.
    • (1994) EMBO J. , vol.13 , pp. 2600-2610
    • Ridley, A.J.1    Hall, A.2
  • 39
    • 0026654125 scopus 로고
    • The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling
    • Ridley, A.J., Paterson, H.F., Johnston, C.L., Diekmann, D., and Hall, A. (1992). The small GTP-binding protein Rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 40
    • 0027441940 scopus 로고
    • Rho family GTPase-activating proteins p190, bcr, and RhoGAP show distinct specificities in vitro and in vivo
    • Ridley, A.J., Self, A.J., Kasmi, F., Paterson, H.F., Hall, A., Marshall, C.J., and Ellis, C. (1993). Rho family GTPase-activating proteins p190, bcr, and RhoGAP show distinct specificities in vitro and in vivo. EMBO J. 12, 5151-5160.
    • (1993) EMBO J. , vol.12 , pp. 5151-5160
    • Ridley, A.J.1    Self, A.J.2    Kasmi, F.3    Paterson, H.F.4    Hall, A.5    Marshall, C.J.6    Ellis, C.7
  • 41
    • 0026613011 scopus 로고
    • Cytochrome b558: The flavin-binding component of the phagocyte NADPH oxidase
    • Rotrosen, D., Yeung, C.L., Leto, T.L., Malech, H.L., and Kwong, C.H. (1992). Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase. Science 256, 1459-1462.
    • (1992) Science , vol.256 , pp. 1459-1462
    • Rotrosen, D.1    Yeung, C.L.2    Leto, T.L.3    Malech, H.L.4    Kwong, C.H.5
  • 42
    • 0023931882 scopus 로고
    • Peripheral actin filaments control calcium-mediated catecholamine release from streptolysin-O-permeabilized chromaffin cells
    • Sontag, J., Aunis, D., and Bader, M. (1988). Peripheral actin filaments control calcium-mediated catecholamine release from streptolysin-O-permeabilized chromaffin cells. Eur. J. Cell Biol. 46, 316-326.
    • (1988) Eur. J. Cell Biol. , vol.46 , pp. 316-326
    • Sontag, J.1    Aunis, D.2    Bader, M.3
  • 43
    • 0024457508 scopus 로고
    • From signal to pseudopod
    • Stossel, T.P. (1989). From signal to pseudopod. J. Biol. Chem. 264, 18261-18264.
    • (1989) J. Biol. Chem. , vol.264 , pp. 18261-18264
    • Stossel, T.P.1
  • 45
    • 0027471215 scopus 로고
    • Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP-binding protein
    • Tominaga, T., Sugie, K., Hirata, M., Morii, N., Fukata, J., Uchida, A., Imura, H., and Narumiya, S. (1993). Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP-binding protein. J. Cell Biol. 120, 1529-1537.
    • (1993) J. Cell Biol. , vol.120 , pp. 1529-1537
    • Tominaga, T.1    Sugie, K.2    Hirata, M.3    Morii, N.4    Fukata, J.5    Uchida, A.6    Imura, H.7    Narumiya, S.8
  • 46
    • 0025840196 scopus 로고
    • Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin
    • Vitale, M.L., Rodriguez del Castillo, A., Tchakarov, L., and Trifaro, J. (1991). Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin. J. Cell Biol. 113, 1057-1067.
    • (1991) J. Cell Biol. , vol.113 , pp. 1057-1067
    • Vitale, M.L.1    Rodriguez Del Castillo, A.2    Tchakarov, L.3    Trifaro, J.4
  • 47
    • 0029145073 scopus 로고
    • Rho family members: Activators of MAP kinase cascades
    • Vojtek, A.B., and Cooper, J.A. (1995). Rho family members: activators of MAP kinase cascades. Cell 82, 527-529.
    • (1995) Cell , vol.82 , pp. 527-529
    • Vojtek, A.B.1    Cooper, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.