Use of parallel synthesis to probe structure-activity relationships among 12-helical β-peptides: Evidence of a limit on antimicrobial activity

Journal of the American Chemical Society

Volumn 127, Issue 32, 2005, Pages 11516-11529

  Porter, Emilie A ^a   Weisblum, Bernard ^a   Gellman, Samuel H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; HYDROPHOBICITY; MICROBIOLOGY; OLIGOMERS;

ANTIMICROBIAL ACTIVITY; HELIX; PARALLEL SYNTHESIS; PEIPTIDES;

BIOSYNTHESIS;

BETA AMINO ACID; BETA PEPTIDE; MAGAININ DERIVATIVE; PEPTIDE; PEPTIDE LIBRARY; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ALPHA HELIX; ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; ERYTHROCYTE; HOST RESISTANCE; HYDROPHOBICITY; NONHUMAN; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; GRAM-POSITIVE BACTERIA; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 23844534446     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0519785     Document Type: Article

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