Immune responses in obesity models

Drug Discovery Today: Disease Models

Volumn 2, Issue 3, 2005, Pages 177-181

  Matarese, Giuseppe ^a   La Cava, Antonio ^b  

^a CNR   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; C REACTIVE PROTEIN; GHRELIN; IMMUNOGLOBULIN G; INTERLEUKIN 1; INTERLEUKIN 6; LEPTIN; LEPTIN RECEPTOR; OKT 3; PHORBOL ESTER; TETANUS TOXOID; TUBERCULIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN SPECIFICITY; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELLULAR IMMUNITY; CHRONIC INFLAMMATION; DIABETES MELLITUS; DISEASE MODEL; FATTY LIVER; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; HORMONE ACTION; HUMAN; HUMORAL IMMUNITY; IMMUNE DEFICIENCY; IMMUNE FUNCTION TEST; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; LIPID METABOLISM; MEDICAL RESEARCH; NONHUMAN; OBESITY; PHENOTYPE; PROGNOSIS; RAT STRAIN; RESPIRATORY TRACT INFECTION; REVIEW; STARVATION; T LYMPHOCYTE;

EID: 26944489607     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2005.08.008     Document Type: Review

References (23)

1. D.E. Cummings et al. Genetics and pathophysiology of human obesity Annu. Rev. Med. 54 2003 453-471
2. K.E. Wellen et al. Inflammation, stress, and diabetes J. Clin. Invest. 115 2005 1111-1119
3. G. Matarese et al. The intricate interface between immune system and metabolism Trends Immunol. 25 2004 193-200
4. A. La Cava et al. The weight of leptin in immunity Nat. Rev. Immunol. 4 2004 371-379
5. K.E. Wellen et al. Obesity-induced inflammatory changes in adipose tissue J. Clin. Invest. 112 2003 1785-1788
6. U. Hanusch-Enserer et al. Acute-phase response and immunological markers in morbid obese patients and patients following adjustable gastric banding Int. J. Obes. Relat. Metab. Disord. 27 2003 355-361
7. S.T. Weiss Obesity: Insight into the origins of asthma Nat. Immunol. 6 2005 537-539
8. D.P. Stites and C. Rodgers Clinical laboratory methods for detection of antigens and antibodies (D.P. Stites, et al. eds.) In Medical Immunology 1997 Appleton & Lange 211-254 254
9. D.P. Stites and J. Folds Clinical laboratory methods for detection of cellular immunity (D.P. Stites, et al. eds.) In Medical Immunology 1997 Appleton & Lange 254-275
10. A.K. Abbas et al. Heterogeneity of helper/inducer T lymphocytes. IV. Stimulation of resting and activated B cells by Th1 and Th2 clones J. Immunol. 144 1990 2031-2037
11. J.M. Zigman et al. Minireview: From anorexia to obesity - the yin and yang of body weight control Endocrinology 144 2003 3749-3756
12. S.I. Farooqi et al. Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency J. Clin. Invest. 110 2002 1093-1103
13. G. Matarese Leptin and the immune system: How nutritional status influences the immune response Eur. Cytokine Netw. 11 2001 7-14
14. Y. Zhang et al. Positional cloning of the mouse obese gene and its human homologue Nature 372 1994 425-432
15. J.K. Howard et al. Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice J. Clin. Invest. 104 1999 1051-1059
16. G.M. Lord et al. Leptin modulates T-cell immune response and reverses starvation-induced immunosuppression Nature 394 1998 897-901
17. J.N. Thupari et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity Proc. Natl. Acad. Sci. U S A 99 2002 9498-9502
18. J.P. McGillis White adipose tissue, inert no more! Endorinology 146 2005 2154-2156
19. S.Q. Yang et al. Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis Proc. Natl. Acad. Sci. U S A 94 1997 2557-2562
20. I.R. Wanless and J.S. Lentz Fatty liver hepatitis (steatohepatitis) and obesity: An autopsy study with analysis of risk factors Hepatology 12 1990 1106-1110
21. A.A. Steiner et al. A new function of the leptin receptor: Mediation of the recovery from lipopolysaccharide-induced hypothermia FASEB J. 18 2004 1949-1951
22. T.T. Tuomisto et al. What have we learnt about microarray analyses of atherogenesis? Curr. Opin. Lipidol. 16 2005 201-205
23. F.E. von Eyben et al. Comparison of gene expression in intra-abdominal and subcutaneous fat: A study of men with morbid obesity and nonobese men using microarray and proteomics Ann. N. Y. Acad. Sci. 1030 2004 508-536